cep290 (cep290)


Basic Information

Item Value
gene id cep290
gene name cep290
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035920.1
NCBI id CM008323.1
chromosome length 47266144
location 26673606 ~ 26715253 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022684351.1
AGCCCCagttttacatgtttaaagTGACTGGTGTTGTAGTATAAAGGCTGTTTGGAGGCTGTGGACAGATTTTGGACACCAAACAAACCGCAAGATGCCTCCAACTACAGACTGGAAAACAGTGATGACTGTTGATCCTGATCTTCTGGGAAGCGAAGAGGAGGAAACCATCTGTGATATTATTCTGCAGGTCCATCCAGGAGAACTGAAGGAGAGCGAGCCTGAGAAAATGGTTCAGCTCTTCAGACTTTCACAGACCTTACTGAGGCTGAAATTGGAGGAAATAATCTGTGCCTATGATGTTGTCGACAAAGCTGGTACTGAACAAGCAAGAATCGAATCAGAACTCAAGGCAAAGATTCTTAAATTAGAAAAGGAACTTGAGATGGCACAGCGCACAACGGGGGGGCGGGACACTCGCTTCCTTCGGGACGAAATTCGCCAACTGGAGAGTCACTTAGAGCGCAAGGAGAAGGAactggtccagttagagaaggaAATGAGTAAAGAGAGGAAAACCAATGAGGAGctgtCACTACGAGCAGAGGAGGCCGAAGATGAAAACAAAAAGCTCAAAAGAGAGAACGAGCAGCTTCATCAGGATGTGGACTTCTACAGGAGAGAACTGGAGCAGAAGGACTCCCTCCAGACCAGAGAGGAAAGCACTGACACTCAAAGGAGACTCAACAAAGCCAGCCAGCAGCTCTACCAGTGCATGGAGGACCTGCAGGTTCTCtggaacacacaaacacacaatccGTTTCTGTTTTATGTTGACTTTCAAATGTATAGACATGTTTTAAGAATCTGGGGTCAGATTCATAAAAGTATCTTAAAAAGAAATCCTGTGAGAGAGCTAACTGAGCAGATCCAGTCTCGGGCTGAGGAGGACGACCCAGTGATGGCTGCAGTCAGTGCTAAAGTGGAGGAGTGGAAGAATGTGTTATCAGAAAAAGATGTGGAAATCATGGAGTACCAGCAGATGATCCGGGACCTGAGAGAAAAGCTAAGAGCTGCTCATTTGGATTCAGACAAAAGCAACATCATCGCACTGCAGCAGGCTGTGCAAGAGAGGGACCATCAGATCAAGCTGCTGTCTGCTCGAGTGGAACAGTACACTGGTGAGATGGAGAAGAATGCCCTGCTTATAGAGGAGCTAAAGAAGccaatgaagaaagaaaaagGTATGGGCTCTACACTGCAGCTGAGGaagctggaggagctgcaggccAAGCTGCAGGCAGCAGAACGACGGGTGCAGCAAGCTGAACGAGAAGCCCATCTAGCTGAGGCCGATGCCCATGAGAAAGACAAGGAGCTGAGCGAGAGCCTCAGCCGTATCCGCCTGTATGAGGCTGGCACTGATGGACTTGAAGCTGCCATAGCTGAGATCAGAGAGTGCAAAAATCAGATCAGGCTCCGAGACAGAGAGCTAGAAGTCATGACCAAGGAAATTAACCAACTGGAACTAAAAATCaatgaccttctggatgagAATGAAGAGCTAAGAGAGAAGCTGGGAATGAATCCAAAAGAAGAAGTGGATTTGACTGAGTTCCGGAGAACAAAGGCACTAAAACAGAGACAGTACAGGGCAGAAAACCAGGTCCTGTTAAAGGAGATTGAGCGTCTGGAGGAGGAgaggctggagctgaagcagcataTCCGCACGTTGGTAAAAGACAAAGGTATCACAGTGCTTAGTAGTTCACTGcttgatgatgatgctgatcaGCATCCTAGCAGGTCCATTAGAGAAAGACCAGACTTCAGAGCTTCTGATGAAAAGATCAAACAGAAAAATGAGTACCTGCAAAATCAACTGAATAGCAGAGAAaaggagctggagctgaagaaAGCAGAATCCTCACAGTTGAAAGCCAGGCTAAATAAGACACAAAAGGAGAATCAGCAACTGGAACAGGATATGAAGGAGATCCTGCAGGCCATCCAGGCACAGAGCAAAAGTCCATCACAGATTGGGATCAGCAGAATCCCCAGCCTGGAAAGACTAATCAGTGCCCTGGAAATTAAGTACTCAGAAGGGAAGGTTGATATAGGCACACATCTGAGGTTTCAGCTAGACCAACTGACCAGCAGGAATGAGGAGCTGAAGCAGGAATTGAAGGCGGCTAGAGAGGAAGCAGCAAGCACACTCTCTCAACTGATGAAGTCCAGTGACAAAGTGGCACGCTTGGAGAGTGAGATCGAGGCAGTAAGACTGTCAGCTGGTGCAGCTGTACCACAAAAGACTCTCCCTTTACCTGAGGAAAGCGCATCATCCAGTGTTAAGACCATTAACTCTCTAAATGAATACATGGTCCAGCTGTTACAGgagaataaaaacaagcaagaCCACAACAAGATGCTCGGACTGGCTTTGGAAGAGTACAAAAGGAAATTTGCAGTCATACGTCACCAACAGGGGCTACTGTACAAAGAATATCAAAGTGAGAAGGAGTCTTGGCAGAAGGAGAGACATTCTTTTGCTGAGTTGAAAGCCAAAATGGAAGAACAGAAGGAGGTGGATGCAGTAAAAATTAAAGAGTATAATAACTGGCTGGAAGCTCTGGAGAAGGACCCAGTTGAGATGAGGAGGCAGGTGTCTGAGGCTGCCCGTAGGATGACTGTGCTCAGAGTAAACGAGAAGTCCCTGACCCGACAGTACACCACCCTGCTGGAGCAGGAGCAGCACTTGAGGAAAGAGAATAACAAGTTAAAGGAAGACTTTGTCCAAATGGAGACTGCAGTCACTAAGCGGATTGGCTATCTGCAGAGATTCAAGGAGATGGCTGCGTTCAAAATGGCAGCGCTCCAGAAAGCGCTTGATGACAGTGTTCCTTCATTCGAGTTGGAGAGGGCAAACAAGCAGTATAATGATCTCACAATCAAATACAGAGATCTCCTTCAGAAGGACAATTACCTTGTTCAGAGGACCACCGGTCTAGAACATATGGAGAATGAAAATGTTTCCCTCCACGAGCAAATCAATTCAGTCAACAAAGAGCTTGAGATCACAAAAGAGAAACTTCACACTCTAGAGCAAGCCTGGGAACACATCAACGACATTGGTGAAGAGAGCAGTATAAACAAGGCAGTGAAGGCCCTGGCAAACAGTGAGATTGTTTCAGTGTCCAAACGCATCACCACGCTGGAGATGAAGGAACTGAACGAGAGGCAGAGAGCTGAGCATGCTCAGAAGATGTATGAGCACCTGAGAAATTCCCTTAAACAGGTGGAGGAGCGCAACCTGGAGCTGGAGGGCAGATTTGCAGAGATGGCCAAACAGAATCTGGAAGCGCAGCGGATCGAGCGTGAGCTACGTGACGAGCTTGCTGACAGTGTCAGTAAAGAAGTCAGTGATGCAGACCGCCAGCACATTGCAGAACTGGAGAAAAGTGAAGCCCAGCTCAGGATCGAGGTGTCCAAGTTACGAGAGGTTTCTGACGTGGCCAAAATGCAGGTTTCTGCACTGGAAGCCAGGCGACAATCCAGAGAGAAGGAGGTTGAGAGTCTCAGAAGGCAGGTGCTCGACTATCAAGCTCAGTCTGACGAGAAGTCCCTTATTGCCAAGCTTCACCAGCACATCGTGGCACTTCAGCTGAGCGAAACGGCAGCTATCAGCAAGCTGGAGGCCTCCACTGCCCGTTTGCTTAAGCTGGAGGCACAACAGTTGCGTGCAGAGCAGCACCTGGACGCTCAACAGCAGGCGTTGTGGCACGAAAGGCAAGAGGGGCGTCAACGTGCCCGGCATCTCCGCCACGCCCTGCAGGCCCTGCGGACGCAGTTCTCTGGAGCTCTGCCACTTGCCCAGCAGGAAAAGTTCTCCAACACCATGCTACAGCTACAGGAAGCACAACAGAAGGCCAGAAAGGACGCGCAAAGAATACAGGAGGAACACAAGATGGCAGAGGGGAGGGCACAGGAACTGGAACTTCGGCTGAAAAGTCTAGAAGAGCTCATGGCCACAATAAAGGATGGTAAAGGAGCACAGAAGGTGAGCGAGTGGCATAAGAAGTTGGAGGAAGCTCGTCTACAGGaactgagaaaaaacagagagctAGGAGCTCAGAGAGAGGAAATCAGGTACCTGAAGAACATGATTGATGAGCAAGAACGCATCATCAGCAGCCTAGAAGAAGAACTGGTGCAACAGAACAATCTACAGGAAGAGCGGCAGCTCTCCTGGGATCACAGGGAAGTGGAGCTCGAGCGACAACTGGAAGCCTATGATAAACAACAGCGTCAAATTATTGGCTCTGCACAAAAGTTTGAAGAAGCAACAGATTCTTTGCCGGATCCAAGCCAGCCTCTTGCCCACCAGCTGGGCCAGGcactaagtaaaataaaagaacatgTTCGCACCATTCTGGAGACACAAGCTGTATGCAAAACTCTTGAGGAGAAGCTAAAGGTGAAGGAGGCAGCACTTTGGCAAGCAGAGCAGAACGTGCTGGCACGAGATCGGGTCATCAATGAACTGCGGCTCCGCCTCCCAGCTGCTGCTGAACGGGAGAGGCTTCTCGCTGACCTGAGCAAGCAGGAAGACTTGAACAGCCAGCCAGCCCTGAAGATCGCTCATCAAACCATCAGCAACCTGCAGGGCCGCCTGGACCAGAAAGAGGAGGTTCTTAAGAAGTACCAAAACCTTCTAGTCAAGGCTAGACAGGAGCAGGAAGAGACATCAAAAAAGCATGACGAGGAGGTGAGAAACCTACACCAGAAGTTAGACCTGCACACAGACAAGTCTTTGGACCACTTCAGACAAACTGCTCAGGAGCTGATGAAGAAACCCACAATCACTGTGCCAACTACAAAGCAGCTGGCACGGCTGGCTGAATTGGAACAGACAGTGGCAGAGCAGGACACGTCCATCTTATCTCTAACACACAAGCTGAAGATGCTGAATGCTGAGCTGGAGAAACAGAGACAGGCCACTGCTTCTCAGGCAAAAGATCACACAGCACAAACAGCCAAgctggaggaGAGACATGCATCTCAAATGAAGGCTGTCTCTCAGGAGGCAGAAGAGCATAGATCCCAAGTCTCTCAGATGGAGAAGGAGCTGCAGTACCTACGTACCGAGCTGGAGGCCCAGAAAGCGGCTAATGTGCGATCTCCAAGTAATACCATGAAGAACCTTGTCGAGCGTCTAAAAGCACAACTGGCTCTCAAGGAGAAGCAACAGAAGGCTCTCAGTAAAGCTCTGCTTGAGCTTCGTGCAGAAATGACTTCCCATGCTGAGCAGCAGATCATTGCAAGTGCAGCCCAAAAGGAAGAGTCCCTCAATATTCAGCAGATTGTAGACAAGCAAACCAAGGATCTAAAGACCCACGTGAAGGAGCTGAGTGAGGAGCTACAGTCCTGGAAGGAGAATGTACGGGCAGCAAAATCTCGCGAGAGCTCTCTGAAGGAGGAGCTGGAAAGCCTCAGCAGAGAGCTGCAGAAGAGTCAGAAGAGCCAGAGCAGACTGCAGAGTGAGAGAGGTGCCCTGGAAGAGCAGGTGGAGGAGCTCAAACAGAAAGTCAGGAGACTCCACAGTGGCCTGCAGGGTCAGACAGAAAGTGAGATTAAAGGCCCCTCTGTAGAGACACTACAGAAGAAGATACGCAAGCTTGAGTCTGAGCTGGACAAGAAGAGTGTGTCAGAGCCTGCAGAAAGAAAAACTTTAGTTAAGGATGACAAGACCTCTAAAGAAGAACTGGTGAGATGGGAAGAAGCAAAGAAATGGCAGGCCAAGGTGGAGAAATTCCAAAACCAtttaaaggagaaagagagacagacagacttgCTTTCCAAACAACTAAATACACTGAAAGAACTCTACGGAAGGTTGGAGCAAGAAAAAGCAGGCCTGCAGAAGAAGCTGAAAAGTCGTGGGGTGACCGCAGATCAGGTGGTAGGTGCACGGACCGTGGAGACTGACAAAGAGATTGAGAGCctaaaaaacagaaactgtgagctggagcagcagattGAAATAATGAAGCTGCAGCAGGCTTTACCACGGGATGCTGCAATGGAGGACATTAACATCAGGAACCGCTATCTAGAGGAGAGGATTTACTCTTTAGAGTCTCAGCTGAAAAAAGACCCTTTTTCTAGGCCATCTACATCAGGCAGGGGCTCTGGAACACCTTCACAAAGGGAGCATGAGCTACAGAAAGACAACCTCAGACTGTCCACTGAGAACCTGGAGCTTCGCTTTCAGCTGGAACAGGCCAACAAAGACCTGCCACGTCTGAAGCATCAGGTTTCTGACCTCAAAGAAATGTGTGATGTGCTCAAAAAGGAAAAAGCTGAAGTGGAGAAGAAGCTTGGGCATGGCCATGGGACTGGGCGAAGTGGAAAGACAGTTCCTGAGCTGGAAAAGACAATTGCACTGATGAAGAAAGTGGTAGAGAAGGtgcagagagagaatgagagtctAAAAAAGAGCTCAGCCACTACGACACAAGAACAGCTCACCACTCTGGAACGTGAACACGAGAAATTCAAGGCTGAATATGACAAGATGAAGGAGAAAATGGATTTTCATCTGACATCAAGACTTGATTCAAAAATGAAAGGAATGGAGAAAATAGTGATGGAAAATGAACGTCTGCACAAAGACATCAAAAAGGTATCTGAGGCTTTAGAGAAGCTAAGAGTAGAAAACACCAGCCTGgttgtaaaaaataagaagcTAAAAGCAGAGCTTGATGAAACCACCCAGAAGCTTCTACTGGCTCAGTCTAAGGGGCCGTCTTTAGAGCGGGCAGATGGCAAGAGCTGGAAATCAACAGTTGTGACCAGGttgtatgaaaataaaatgaaagaccTCGAGAGTGAACTCTCTAAAAACAAGGCAAGTATCTCTGAGTTCAATTTAAAGCTCAAAGAGTCCCACGAGAGAGAGAAGGACGCTCAGCGCACTATCATACAGCTAAAGGAACAAGTAGAGCTCTTGAAAAATACACCCATAGAAGGAATCACTGAGGAGGGCCTTGCTCAGCAGTTTCAGTCTCATagACTCACAATCAATCAGCTGGAGAGGGAGAAGACTCACCTTCTTCATCAGATAAAGAACTATGAAGAGCAATTTGAAACCAGCAGGATTGGACCTGgaAACAAAGAGCTTCAAGCCCAATTAAATGCAGCCAATGCTGAAAGGAGTCACCTACAGGATGAAATTAGAAAAATGAGCAATGAACTGGCAAACTTTGACCCAACCTTCTTTGAGGAGCTTGAGGATTTGAAGTTCAATTATAATGTGGAGGTGAAGAAAAACATCATTCTGGAGGAACAGCTTAAAAAACTTTCAGAACGCTTTGGAGTACCAGTGGACATCCCAACAGACGGATCACTCAGCTAACACAAAACATCTGTCCAGGAGGTTGAAGAAACAGAACTTTGTACACAGAGAATAGAGAAtggtcaaagttttttttttttgtttttttttaatgattagtttTATGTGAATTTGTATAGTTATGTATATTATAAGTCAGCTGTGCTTTTTGTAATATGATAGAACAATGTGACGTTTTCTATGGTGATGATTTGTGGCCTCATACGGACaggccaaatgtcatgggatggCAACAAGTATTGTGTAGGACCCCTCCAGCTGGGCAAAGTGCAGAAACACAACAAGGCATCAGTTCTGCAAGTGGAGTTTGGAACAAGCCATTCATTAAAAAGATCTAAAAGAACA

Function

symbol description
cep290 Involved in hindbrain development. Acts upstream of or within several processes, including DNA damage response, detection of DNA damage; animal organ development; and photoreceptor cell maintenance. Predicted to be located in centrosome and nucleus. Predicted to be active in centriolar satellite and ciliary transition zone. Is expressed in gut; nervous system; notochord; and post-vent region. Used to study ciliopathy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 14; Joubert syndrome 5; Leber congenital amaurosis 10; Meckel syndrome 4; and Senior-Loken syndrome. Orthologous to human CEP290 (centrosomal protein 290).

NR:

description
centrosomal protein of 290 kDa

GO:

id name namespace
GO:0021549 cerebellum development biological_process
GO:0043010 camera-type eye development biological_process
GO:0048793 pronephros development biological_process
GO:0042462 eye photoreceptor cell development biological_process
GO:0015031 protein transport biological_process
GO:0007369 gastrulation biological_process
GO:0060271 cilium assembly biological_process
GO:0030916 otic vesicle formation biological_process
GO:0042995 cell projection cellular_component
GO:0005813 centrosome cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component

KEGG:

id description
K16533 CEP290, NPHP6; centrosomal protein CEP290

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022684351.1 True 7699 mRNA 0.47 51 26673606 26715253

Neighbor

gene id symbol gene type direction distance location
LOC103031232 arntl1a,LOC108439331,LOC107707455,LOC107753525,LOC107665721,LOC108269000 coding downstream 33383 26613862 ~ 26640223 (-)
LOC111195836 NA coding downstream 427185 26244248 ~ 26246421 (-)
LOC111195834 NA coding downstream 573779 26096805 ~ 26099827 (-)
LOC111195867 NA coding downstream 578415 26092170 ~ 26095191 (-)
LOC103040521 NA coding downstream 987995 25681230 ~ 25685611 (-)
kitlg NA coding upstream 77509 26792762 ~ 26815459 (-)
LOC111195856 NA coding upstream 231041 26946294 ~ 26949370 (-)
LOC111195857 NA coding upstream 236436 26951689 ~ 26953473 (-)
LOC103031696 ano1,LOC105911290,LOC106573096 coding upstream 311241 27026494 ~ 27233590 (-)
LOC111195765 NA coding upstream 393046 27108299 ~ 27111038 (-)
G208395 NA non-coding downstream 16190 26656489 ~ 26657416 (-)
G208392 NA non-coding downstream 24919 26648477 ~ 26648687 (-)
G208390 NA non-coding downstream 27667 26645672 ~ 26645939 (-)
G208386 NA non-coding downstream 38066 26632153 ~ 26635540 (-)
G208357 LOC108439330,LOC107665709,LOC105895626,LOC107753524 non-coding downstream 85216 26586222 ~ 26588390 (-)
G208417 NA non-coding upstream 74387 26789640 ~ 27220851 (-)
G208438 NA non-coding upstream 125036 26840289 ~ 26871460 (-)
G208445 NA non-coding upstream 144158 26859411 ~ 26863216 (-)
G208446 NA non-coding upstream 146388 26861641 ~ 26881461 (-)
G208447 NA non-coding upstream 148133 26863386 ~ 26868253 (-)
G208394 borcs5,LOC107753635 other downstream 17422 26655443 ~ 26656184 (-)
G208046 NA other downstream 460765 26212058 ~ 26212841 (-)
LOC111195835 NA other downstream 555974 26103487 ~ 26117632 (-)
LOC111195761 NA other downstream 585191 26086651 ~ 26088415 (-)
LOC111195762 NA other downstream 587102 26079764 ~ 26086504 (-)
wwp2 wwp2,LOC108439047,LOC107740243,LOC107560080 other upstream 1501142 28216395 ~ 28268369 (-)
LOC107197304 NA other upstream 1946930 28662183 ~ 28695700 (-)
lrp5 lrp5,LOC107654131,LOC107714037,LOC107581849,LOC107701817,LOC106573620 other upstream 2067830 28783083 ~ 28860774 (-)
G209090 NA other upstream 3308708 30023961 ~ 30024550 (-)
G209127 NA other upstream 3447204 30162457 ~ 30162973 (-)

Expression


Co-expression Network