Gene
RNA
| Item | Value |
|---|---|
| gene id | tcf7l2 |
| gene name | tcf7l2,LOC107755529,LOC107566231,LOC106949585 |
| gene type | misc |
| species | mexican tetra (Astyanax mexicanus) |
| category of species | ornamental fish |
| Item | Value |
|---|---|
| chromosome id | NC_035900.1 |
| NCBI id | CM008303.1 |
| chromosome length | 25652880 |
| location | 5255619 ~ 5362486 (-) |
| genome version | Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome |
| symbol | description |
|---|---|
| tcf7l2 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in digestive system development. Acts upstream of or within several processes, including diencephalon development; exocrine pancreas development; and intestinal epithelial structure maintenance. Located in nucleus. Is expressed in several structures, including anterior neural plate; brain; digestive system; gonad; and sensory system. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in colorectal cancer; diabetes mellitus (multiple); pancreatic cancer; and prostate cancer. Orthologous to human TCF7L2 (transcription factor 7 like 2). |
| description |
|---|
| PREDICTED: transcription factor 7-like 2 isoform X1 |
| id | name | namespace |
|---|---|---|
| GO:0060070 | canonical Wnt signaling pathway | biological_process |
| GO:0006357 | regulation of transcription by RNA polymerase II | biological_process |
| GO:0060729 | intestinal epithelial structure maintenance | biological_process |
| GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis | biological_process |
| GO:0007420 | brain development | biological_process |
| GO:0048699 | generation of neurons | biological_process |
| GO:0005667 | transcription regulator complex | cellular_component |
| GO:0043565 | sequence-specific DNA binding | molecular_function |
| GO:0003682 | chromatin binding | molecular_function |
| GO:0003700 | DNA-binding transcription factor activity | molecular_function |
| GO:0008013 | beta-catenin binding | molecular_function |
| id | description |
|---|---|
| K04491 | TCF7L2; transcription factor 7-like 2 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| XM_007259212.3 | False | 4426 | mRNA | 0.44 | 15 | 5255619 | 5362470 |
| XM_007259213.3 | True | 4428 | mRNA | 0.44 | 15 | 5255619 | 5362472 |
| XM_007259214.3 | False | 4410 | mRNA | 0.44 | 15 | 5255619 | 5362469 |
| XM_007259215.3 | False | 4412 | mRNA | 0.44 | 15 | 5255619 | 5362471 |
| XM_007259216.3 | False | 4395 | mRNA | 0.44 | 15 | 5255619 | 5362469 |
| XM_007259217.3 | False | 4376 | mRNA | 0.44 | 14 | 5255619 | 5362471 |
| XM_007259218.3 | False | 4360 | mRNA | 0.44 | 14 | 5255619 | 5362464 |
| XM_007259219.3 | False | 4359 | mRNA | 0.44 | 14 | 5255619 | 5362469 |
| XM_007259220.3 | False | 4360 | mRNA | 0.44 | 14 | 5255619 | 5362470 |
| XM_007259221.3 | False | 4343 | mRNA | 0.44 | 14 | 5255619 | 5362462 |
| XM_007259222.3 | False | 4328 | mRNA | 0.44 | 14 | 5255619 | 5362462 |
| XM_007259223.3 | False | 4278 | mRNA | 0.44 | 13 | 5255619 | 5362463 |
| XM_007259224.3 | False | 4279 | mRNA | 0.44 | 13 | 5255619 | 5362464 |
| XM_007259225.3 | False | 2244 | mRNA | 0.51 | 16 | 5257878 | 5362486 |
| XM_007259226.3 | False | 2156 | mRNA | 0.51 | 15 | 5260389 | 5362486 |
| XM_007259229.3 | False | 2207 | mRNA | 0.51 | 16 | 5257878 | 5362485 |
| XM_007259230.3 | False | 2119 | mRNA | 0.51 | 15 | 5260389 | 5362485 |
| XM_007259231.3 | False | 2162 | mRNA | 0.51 | 15 | 5257878 | 5362479 |
| XM_015608357.2 | False | 4375 | mRNA | 0.44 | 14 | 5255619 | 5362470 |
| XM_022668937.1 | False | 4293 | mRNA | 0.44 | 13 | 5255619 | 5362463 |
| XM_022668938.1 | False | 4260 | mRNA | 0.44 | 13 | 5255619 | 5362466 |
| XM_022668939.1 | False | 4228 | mRNA | 0.44 | 13 | 5255619 | 5362464 |
| XM_022668940.1 | False | 2167 | mRNA | 0.52 | 15 | 5261507 | 5362485 |
| XM_022668941.1 | False | 3721 | mRNA | 0.43 | 11 | 5255619 | 5282602 |
| XM_022668942.1 | False | 2156 | mRNA | 0.52 | 15 | 5257878 | 5362485 |
| XM_022668943.1 | False | 2049 | mRNA | 0.51 | 14 | 5257878 | 5362483 |
| XM_022668944.1 | False | 2005 | mRNA | 0.51 | 13 | 5257887 | 5362480 |
| XM_022668945.1 | False | 1855 | mRNA | 0.51 | 11 | 5257887 | 5362483 |
| XR_002649848.1 | False | 2251 | misc_RNA | 0.51 | 16 | 5257882 | 5362485 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| LOC103030716 | crygmxl2,LOC103030716,LOC108426411,LOC106516994,LOC104933141,LOC103368160,LOC107581669,LOC107702435 | coding | downstream | 89994 | 5163950 ~ 5165625 (-) |
| LOC103029658 | crygmx,LOC103029658,LOC108426431,LOC107684144,LOC107566847,LOC107755411,LOC107581668 | coding | downstream | 92153 | 5160908 ~ 5163466 (-) |
| entpd1 | NA | coding | downstream | 130421 | 5099968 ~ 5125198 (-) |
| mrpl43 | mrpl43,LOC107722220,LOC107581592,LOC107565786 | coding | downstream | 324912 | 4927516 ~ 4930707 (-) |
| mfsd13a | mfsd13a,LOC107565800,LOC107581593,LOC107684076,LOC107690908,LOC107755491 | coding | downstream | 376860 | 4870049 ~ 4878759 (-) |
| vti1a | vti1a,LOC107566351,LOC107702459 | coding | upstream | 38442 | 5400928 ~ 5571634 (-) |
| acsl5 | acsl5,LOC107702457,LOC107755526,LOC107566323,LOC107581566,LOC107722228,LOC107684041 | coding | upstream | 216844 | 5579330 ~ 5596438 (-) |
| tectb | tectb,LOC107755437,LOC107566341,LOC107702437,LOC107722201 | coding | upstream | 237882 | 5600368 ~ 5687159 (-) |
| nrap | nrap,LOC107755535 | coding | upstream | 409133 | 5771619 ~ 5803122 (-) |
| LOC103041412 | LOC103041412,LOC108426492 | coding | upstream | 456236 | 5818722 ~ 5822431 (-) |
| G34556 | NA | non-coding | downstream | 61760 | 5191033 ~ 5193859 (-) |
| G34543 | aldh18a1,LOC107707764 | non-coding | downstream | 103206 | 5151372 ~ 5152413 (-) |
| G34544 | aldh18a1,LOC107684039 | non-coding | downstream | 104656 | 5150310 ~ 5150963 (-) |
| G34542 | NA | non-coding | downstream | 111563 | 5143724 ~ 5144056 (-) |
| G34541 | NA | non-coding | downstream | 112284 | 5143072 ~ 5143335 (-) |
| G34682 | NA | non-coding | upstream | 28609 | 5391095 ~ 5391320 (-) |
| G34688 | zdhhc6,LOC107684040,LOC107722226,LOC107581631 | non-coding | upstream | 210987 | 5573473 ~ 5574758 (-) |
| G34708 | NA | non-coding | upstream | 282420 | 5644906 ~ 5645105 (-) |
| G34713 | NA | non-coding | upstream | 296538 | 5659024 ~ 5659904 (-) |
| G34719 | cpn1,LOC107722209,LOC107684044 | non-coding | upstream | 314932 | 5677418 ~ 5681939 (-) |
| psme4 | psme4,psme4b,LOC108426507,LOC107584369,LOC107749369 | other | downstream | 259706 | 4971698 ~ 4995913 (-) |
| G34214 | NA | other | downstream | 1372150 | 3836621 ~ 3883469 (-) |
| prr15l | prr15l | other | downstream | 1466427 | 3783125 ~ 3789192 (-) |
| G34046 | NA | other | downstream | 2061242 | 3181168 ~ 3194377 (-) |
| G33904 | NA | other | downstream | 2946290 | 2303262 ~ 2309329 (-) |
| ccdc186 | ccdc186,LOC107755417,LOC107689962 | other | upstream | 541102 | 5903588 ~ 5928154 (-) |
| G34770 | NA | other | upstream | 573349 | 5935835 ~ 5939400 (-) |
| ablim1 | ablim1 | other | upstream | 686515 | 6049001 ~ 6147311 (-) |
| LOC103026268 | bahcc1 | other | upstream | 1004198 | 6366684 ~ 6513701 (-) |
| G34953 | NA | other | upstream | 1174535 | 6537021 ~ 6541364 (-) |
