adrb1 (adrb1)



Basic Information


Item Value
gene id adrb1
gene name adrb1
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035900.1
NCBI id CM008303.1
chromosome length 25652880
location 5887044 ~ 5891991 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007259258.3
GGCTCGCGCTCCGAGTGCAGGACGGATGGAGCGCGGCGGCGAGGATGGCGCGCCACACGGGAGCGCGTGCTCGGCGGACAGCGTGAGATCGGGACGCGGAGCGCGCGGGGGTCCCAGCATGGGCGACTACGGCAACGGCTCGAGGCGCGGGCGTGCGGAGTTGCCCCCGGGCCCCTCGGAGCAGTGGGCGGTGGGCATGGCCGCGGTCATGGCCCTCATCGTGCTGGTGACTGTGGCGGGCAACGCGCTGGTGATCTTGGCCATCGCGCGCACACACCGCCTGCAGACGCTCACCAACGTGTTCATCACATCGCTCGCGTGCGCCGACCTAATCATGGGCATGCTGGTGGTCCCGTTCGGCGCCGCGCTGCAGGTGCGCGGCGCGTGGCTCTATGGCTCGTTTCTGTGCGAACTGTGGATCGCGCTGGACGTGCTGTGCGTCACGGCTAGCATCGACACCCTGTGCGTCATCGCCGTGGACCGCTACGTGGCCGTGACGCGGCCGTTTCGGTACCAGAGTTTGCTGACCAAGGCGCGCGCCAAGGTGGTCGTGTGCGCAGTGTGGGTGGTGTCGGCACTCGTGTCCTTTCCCCCCATCCTGCTGCACTGGTCCCGGAGCACGGAGGACACGGCATGCTATGAGGACCCGGAGTGCTGCGACTTTGTGACGAATGGCGCGTACGCTGTGACCTCATCCGTCATCTCCTTCTACCTGCCACTGGTGGTCATGGCCTTCGTGTACGCGCGCGTCTACGGGGAGGCCAAGAAACAGTCAAGGAAGATTGACCGCTGCGAGGGTCGCTTCCACAATGGCGGTGCCAAGGTGCTGGGTGCCAAGGAGCAGAAGGCCCTCCGGACCCTCGGCCTCATAATGGGCACCTTCACCCTCTGCTGGCTGCCCTTTTTTGTGGCCAACGTGGTGCGTGTGTTTCGCCCAAGCGCCGTCCACGACCACCTCTTTGTGTTCCTCAACTGGCTTGGCTACGCAAACTCTGCCTTCAACCCCCTCATCTACTGCCGCAGCCCAGACTTCAGGCGCGCCTTCAGGGCACTCCTGCGCTGCGATCGGACATTTGTAGGAGCCACTGAAGCACTGGATCCCTGGCGCCCCACTGCTGTCAGCACACCAGAGCCCACTGCGATGGCTATGTACTCTCGCTGTGATGAAGGTGGCATCACAACCCGGTGCTGAGGTTTGATTAATTGACTGACCCAAATAACATGCCAGTCAGAGTATGGGCTCTATGGATAGCTCAGCTAACTTGGTTGGGTCCCATGTTGGCCCCATGCACATATGGATGTCGGCGAAGGGCCACATCAGGGTCAGTGATGGAAGCAGGAGGGTTTAATCATGGGCCCCATCTGTGGCCTAGATGGGTCCAGGTGAGATTAAGGGGGGCTGTAACGATGGGTCACAGTAACAATACATCTACAAAGCCCATAACCACCTGGAACCTGCCCGGCCCACCCTCCACCCATATGGCATTTTGGCTGGGGATTGACGCACTCACAGACATGAGGATTACAGATGTGGATGGAAAACCCCACCAGTGGGATTTGGTGGGATTGGAGTGATGGGACATGTGTTGTGTCTATAAGGCAAAACAGCACGGATAGAAAACAATTTGAAACTTGATTGCGGTTTAAGATGTGATTTATTTTGTCCCATACAAACTGCCAACTTACTGCAGCCACACACATATAGGAGAGCTGGAAGAATGCAGACATGACTCTGTTGCCAGATCAAATTTTTTTCTGCCCCTATTTCAGCCCAAACCAGGACTAAATGGAGCCCAAAAATAGACCCAACATCTGACCTAGAAatggcctgttttctgcagcTATAGGGTGGCCTTAGGTATTTATTATAGGACATTCTTAAAAATGAAAGGATTCTTTGAgcgatgccatagaagaaccacttttgtttCCAAAAAGAACCTTTCTGAAGTAATGTCAAGTGTGAAGAATCTTTTAAATCTTAAGAGTAAAGACTTTTGGCCGTCGTTTAAAGAACGCTTAAAAGCATCTGTATCATTGAAAGATTTAGTGAAAGATGATGGGTGGAAAAGGTATTTCATCTGTATAATTTACTAACTGAGCAGAATGCAGATGGGTTTGGTGTAAGATGGTTTACTGGAGAgaaatttgctgttttatttttttgttctcagTGGTGCTGATAGGAACCACAGCTCACAGAGTCCACATGGATCATTTTGGAGGTCTGGTTCGATCAAGCACCACCACcatagtgaataataataatagacttAGAAAGTTTTTCTTAAACAGTGAATTTCACACCAAAGTAGAACTGgacaataattaattattattatttatcacaatataaaatgttttaattagggTCATATGATTTTCAAAcacatttctaatattttattatactattatataatattattacagtATCTGTCCCTGACTGACGTTCATTACTGGATAAATTACATCAATAggcaaattaatttttttagaaattCGTAGGTTTGTATGTTTTGTGCAAGGTCATATTAAATTCAAGGTCATATTAAGTTGTTATTTGATGCAAACAGAAAATTCAAACTATTCTCATTTTCCATGACAAATCTTACAGAGgccataataatatattttactccAACTTGGCACTGTTCCcactgttttattattgcattattaatatcatatcATGTCAAATTGGATTACTGACTGGTAACATCCTGGAAGAATcccttaatattttttaatatggcTATTTATATACAGCAGACAAAATTCtgcaatgtcagtttttattcagatattgtgtacacctgTGTCCCATTCAAGCATATATGTGTACAGTAGCATACCATCCCTGTTAACCATTTATGTCCATTAATATCTACCTATAGACCACCCAGCAAGCACAGTAATTGTGAGAGGAACTGATTGTGAGATCATACTGtgtataaatgttgttttttgtagGGTTGCCAACTTTTCTGCCCGTTTTGAAGCCCAGCTGAGGCTTAAAACTTGCAGACTCAGATAAACCCTGCCCTCTATTTCGCCCTACACTCAGGCATCTGTCCCGTATGTGCAGAAACAGACTTCCCTTATGGCTCTCAAACAATGTagatttgtttctgttttaactAAGAGAAAAATTACAAACTCATGAACATCCTCCTCCACCTTCTAGGAAAAATAAACGAGAAAGGCCAGAGTCTATTCTGATCTGCTTGTTTCTTTAGGCCTGTTTGTTTTTAGTTAGCAATCGTTCCTGAATGCTGATGTTGAATTGAATTGACTGTTTAAAAGGGACTTTAGTAAGGTTTCTTACAGTGGGAATTTCATCTTAactgaaagagaaatagagtaTGCTCTTTGTGATGCTTAATCAACCATTTAGGAATTTAGAAATTTGtgataaaatagctttttgttCACCTACAAATAAAAACCCCAAACAGCAAAACTGCTGGCAACAGTTTGATGCTGCCAGCATTGCTCCGCATGCTTATGTAATAACAGCCCACCAGTCTCAGATGTCTGGTTAATAACTGCCTGAGCCTTATGAGTGAATAAATGTGGATAAACTGGTTAATAGCTGCGTCCATAATGGCTGGGtttaaaaatctacttttttatACCAAACAATATTACTTTAAATGTTCTAATATATCGATTAACGTAAACCTGAGATTGGTCTTTAAAATGTgcctattttgaaaaaaaaaaaaacaatatataaatattaatattttaaattgtggtAAGTTGAGGGTTCCTTGTGCAATTACAACAATTCATTTTCTGAAGATCTCTTtttatatacaaacaaaatCTGTTATATAAAATGGAATTGGGAATCTGATTGAATTGGGAATCAAAATAATTTGGGGAATCAGTggtgatacccagccctaataaacagccaatcacacaaaGGACACTATCATTAGTACTGATAATTTGTCTTCATAGTAGATATAGTACAGTAGTATGTAGTATAAACTCCATGCTATTGCACTATATTGTTTTCCAGTATGCCAGAAATAGCACACTGTTATTAGTATTCCATTCCTTAGTACATAATGGAGAGGTTTCTCAGTCCAAGATTAAGCCTAGCTTTGGACTACACGGCATTTTTGAATGAAGATTTTCTACAGAAAGTAAACCATACCAATATAGTACAGTAGTACAGTATGTGGTTTCAGATGCAGCCTCAGTGTAAATAATAGCAGTgcaaaaaagccaaaaatgaggtcctttttattaaatattaaaactctCTGCTACTATTTTCCCCAAACAATATGAGAAAGTAGTTCAGTTGTGCAGAACATCGCCCAAGTTGGCAACCCTGTGAATTTGTTCTGAGTTGGCTTGAGCACTTCTGCAAATCCAGGCTTTTCATTTTCAGCAGCAGTTTTCACTAAACCTCCAGCTTTCATATTGTACATACGAATGTGACGTTTGAAGAAATCTCCTTTTACagccttactttacctcatacCTTAGAAATGTGCAAATTGTACGAAAGGaaattgtttatattaaacaaccTTTTCAaactatacagtatttatttggtACTAAGTAGGCTGTAGCTGATGGAGTAAGCTTGATAAAGTGTCAGGAAAATTATCATATAAAGGGAACTGTGATTCATTGCTACCTTTGCACCATCTATTTTGTCTAATGTGAGCGAGCTGCTTCTTTTCTCCTTTAGTATTGTAttactatttaatattttaatacatcgGTTTGcctaattattaaaaaagggGCTTAGTATTTTATTCATTGACGCACAAATAGGCCTGGTTCTGTTTTATGTAGTGCAATTTCTGCCCAAATGCCATATATCTGCATTAGTAATTCATGTAGCAATGCCTGATGTAATGTATAAGGTCTTCATGTTTACGAGTGTGGAATAAAGTGTCCTATTGAAAACACA

Function


symbol description
adrb1 Predicted to enable beta1-adrenergic receptor activity. Acts upstream of or within regulation of heart rate. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adipose tissue; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypertension (multiple); low tension glaucoma; obstructive sleep apnea; and periodontitis. Orthologous to human ADRB1 (adrenoceptor beta 1).

NR:

description
PREDICTED: beta-1 adrenergic receptor

GO:

id name namespace
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway biological_process
GO:0002027 regulation of heart rate biological_process
GO:0045823 positive regulation of heart contraction biological_process
GO:0005886 plasma membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004940 beta1-adrenergic receptor activity molecular_function

KEGG:

id description
K04141 ADRB1; adrenergic receptor beta-1

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007259258.3 True 4948 mRNA 0.43 1 5887044 5891991

Neighbor


gene id symbol gene type direction distance location
nhlrc2 nhlrc2 coding upstream 11830 5852907 ~ 5875214 (+)
plekhs1 NA coding upstream 45201 5829634 ~ 5841843 (+)
LOC107197901 NA coding upstream 59035 5824388 ~ 5828009 (+)
casp7 casp7 coding upstream 67047 5807162 ~ 5819997 (+)
LOC103045303 NA coding upstream 115167 5765856 ~ 5771877 (+)
tdrd1 NA coding downstream 12115 5904106 ~ 5948629 (+)
vwa2 vwa2 coding downstream 57553 5949544 ~ 5981217 (+)
LOC111192358 LOC108426481 coding downstream 108015 6000006 ~ 6002530 (+)
trub1 trub1,LOC107755443,LOC107702428 coding downstream 257296 6149287 ~ 6152869 (+)
LOC103024806 LOC108426520,LOC108274104,LOC107601442,LOC107755481,LOC107581599,LOC107690914,LOC107684082,LOC107722230 coding downstream 288833 6180824 ~ 6185239 (+)
G34636 dclre1a non-coding upstream 39119 5844902 ~ 5847925 (+)
G34602 NA non-coding upstream 93226 5788758 ~ 5793818 (+)
G34615 NA non-coding upstream 144600 5739614 ~ 5742444 (+)
G34606 NA non-coding upstream 227142 5659266 ~ 5659902 (+)
G34605 NA non-coding upstream 227845 5658969 ~ 5659199 (+)
G34644 ccdc186,LOC107755417,LOC107566113 non-coding downstream 22250 5914241 ~ 5916402 (+)
G34657 NA non-coding downstream 74697 5966688 ~ 5967194 (+)
G34790 NA non-coding downstream 150855 6042846 ~ 6043340 (+)
G34841 tmem235 non-coding downstream 366562 6258553 ~ 6258814 (+)
G34842 NA non-coding downstream 374318 6266309 ~ 6266668 (+)
dnmbp dnmbp,LOC107722208,LOC107684043 other upstream 130928 5692522 ~ 5756116 (+)
LOC103025551 sema4g other upstream 962278 4882556 ~ 4924766 (+)
G34309 NA other upstream 1708961 4171051 ~ 4178083 (+)
tbkbp1 tbkbp1,LOC107565677,LOC107754096,LOC107677885,LOC107743771 other upstream 2227912 3564030 ~ 3659132 (+)
amz2 amz2 other upstream 3830081 2050742 ~ 2056963 (+)
LOC103045604 LOC108426437,LOC107683136 other downstream 354655 6246646 ~ 6258050 (+)
slc38a10 slc38a10,LOC102792191,LOC107749860 other downstream 610154 6502145 ~ 6541460 (+)
LOC103029551 qki2,LOC103029551,LOC108426533,LOC107684089,LOC108274051,LOC107749853,LOC107755469 other downstream 700616 6592607 ~ 6663607 (+)
G34931 NA other downstream 838963 6730954 ~ 6731424 (+)
G35021 NA other downstream 1010426 6902417 ~ 6903997 (+)

Expression



Co-expression Network