prodh2 (prodh2,zgc:92040)



Basic Information


Item Value
gene id prodh2
gene name prodh2,zgc:92040
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035900.1
NCBI id CM008303.1
chromosome length 25652880
location 17929307 ~ 17939085 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_022669244.1
TCTGGTCTCCTTTCATTGTATATTGACCTGCTGCGTGAGTTCATGCAGGGCAAAGCTTTCACTTTGTAACAGCTGCTGTTCTTGGTGCTGCCGGCTGAAGCTTGCAACGAagacaaaacagagagagatctGGAGGAGGTCTATTGGGTCTTTTGAAGTTTCATGCCAAAGATGTCTTCTGTTCTCCGGCCGTCCACGTTCTACCCCATCCTTTCACTCCGAATTACAAGTGTGTCTTCTAGGATGTTGGCATCACAAGTTGCACCTCTGAGAACTCCTGTTCCGCCGACTCTGCTGACCTTTGAGGACCCGCGGGCGTTCCAGGCGAAGAGCTGGTGGGAGCTCACGCGAGCTCTGGGGGTTTTCAGACTCTGCTCCTTCCCTGTGCTGGTCAATCACTGTGGTAAGCTCATGTCATTTACTCGGACCATCCTGGGAAAAAGAGCTTTTGCTATGGCCCTTCGCCCGTTTGTATACGCCCAGTTTGTTGCTGGGGAAACTGAGGAGGAGATTGCAGAGTCCATGGAGAAAATGAGCTCACTGGGACTGCGCCCCATGCTGGCCGTCCCCATTGAGGAGGACCTGGGAGAGAGCACTGGAGAGCAGAGGTACGATGACAACCTGGCGTCCATGTTGGAATGTGTGCGAATGTCTCACCACAACACATGGAGCAAAGATCCTATGATGCAACTGAAGATCACTGCGCTGGTCAGCCCTGAGCTTTGTGTAAAGCTGACCTGCCTGCTACAGGAACAGCAGTATGATCTGAACCTCTTGGTTAAAGCTATGGATGGAGAGGTCATAGTGTTTCCAGGCCTCAGCGAGAGTGAAAACACACATTTCCTGTACGGCCTTCGCAGACTAAATGAAATAGGAGAGGCGAGTATAAATAAAGTCAGGGTTCTGGTGGATGCTGAATACACGTATATGAACCCTGCCCTCTCCCTCATCACTATGGCCATGATGAAGAAGTTCAATCAAGATGGAGCCTGGATTTGGAACACCTACCAGTGCTACTTAAAGGAGTCCAGGGATCTCTTGCTTGATGCCGTccgtctgtctgtggagcagtcCTTCTGTCTCGGGGTTAAGCTGGTCAGAGGAGCGTACATGGACAAGGAAAGGAAACTAGCCGACAAGGAGGGACGAGCCGACCCCGTGCACCAATCCTGGGAGTACACCAATGACTGCTACAACGGCTCTTTGGAAATCATGCTGAACCTCATCTCTCAGCATCCCCAGCGCTACAAGATCATTGTAGCAACACATAACGAAGAGTCTGTTAGAAAAGCAGTGACGAGGATGACTGAGTTAGGCATCGATCGAGACGGCGGCGCAGTTTGCTTCGGTCAGCTGTTGGGGATGTGTGACCATGTGTCTCTTACTTTGGCTCAGCAGGGTTTCTCTGTGTATAAGTCGGTTCCGTACGGCTCGGTTGACGACACTTTGCCCTATTTGGTGCGTCGGGCTCAGGAGAACCGCACTGTTCTGCAGGGCATCCGCAAAGAGAGAGACCTGCTGCGCCAGGAGCTCCGCCGCAGAGTCCGGGAGAAGATCACTGGAGCCAAATAGATCCATATTACAGGGACTGTTCAGatataaatcagatttacaCTGATTTCTTTACTCCACATGTAGAATCATGTAGCTCTTTTAGCTTCTGCTAAATATCTCAGGAAGGAGGGGGGCAGATATTATGATGATATGATTTTATGGTGACCTGTTCAGTTTTAACAGCTGTCTAACTTGGCACCTTGCTttacacaattattattattattatttttggtaacattGTGTAGCATTACCTTCAGTAATCAATACATAGCATTATCAGTATTTATCTACAATCTACACATTGTACAGTATTTGTGGACTGATATGAGAAATTTATTGTAAATTCTGTCTTAAATAAATTGATTTTGGTTTTATAATGAAACaatcattacattacttttggccgacacttttatccaaaagACAGACAGGACTTTATTTTAGGTGCGAAAGATACAGAATAAAGATATAATACtctatttttcgcactataaggcacaccagattataagggatcaataaacgtctattttctgctctattttcatacataaggcccaCTGGATTATAACGct

Function


symbol description
zgc:92040 Predicted to enable FAD binding activity and proline dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to act upstream of or within proline catabolic process. Predicted to be active in mitochondrion. Is expressed in liver; pancreas; pronephric duct; and yolk syncytial layer. Orthologous to human PRODH2 (proline dehydrogenase 2).
prodh2 Enables oxidoreductase activity, acting on the CH-NH group of donors. Predicted to be involved in proline catabolic process to glutamate. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion.

NR:

description
hydroxyproline dehydrogenase

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0006537 glutamate biosynthetic process biological_process
GO:0006562 proline catabolic process biological_process
GO:0004657 proline dehydrogenase activity molecular_function

KEGG:

id description
K11394 PRODH2; hydroxyproline dehydrogenase

RNA


RNA id representative length rna type GC content exon number start site end site
XM_022669244.1 True 2132 mRNA 0.47 12 17929307 17939085

Neighbor


gene id symbol gene type direction distance location
LOC103022355 NA coding downstream 10510 17904204 ~ 17918797 (-)
taok2 taok2b,LOC107693686,LOC108273910,LOC107562015,LOC107708977,LOC107571768 coding downstream 57153 17839427 ~ 17872154 (-)
maz maz coding downstream 92401 17822758 ~ 17836906 (-)
LOC103047174 fam57b,fam57bb,LOC108274141,LOC106583943,LOC107578766,LOC106579402 coding downstream 109027 17803734 ~ 17820280 (-)
wnk4 NA coding downstream 145029 17711000 ~ 17784278 (-)
LOC103023166 LOC108425993 coding upstream 2765 17941850 ~ 17960291 (-)
ppp4c ppp4c,ppp4cb,LOC105024361,LOC107590569,LOC107690278 coding upstream 22845 17961930 ~ 17971020 (-)
LOC103023915 NA coding upstream 33503 17972588 ~ 17986489 (-)
LOC103046263 NA coding upstream 52982 17992067 ~ 18015094 (-)
aldoa aldoa,aldoab,LOC101465268,LOC107720037 coding upstream 103957 18043042 ~ 18056729 (-)
G37333 LOC103045739 non-coding downstream 220702 17705734 ~ 17708605 (-)
G37309 NA non-coding downstream 373385 17553572 ~ 17555922 (-)
G37298 tmem101,LOC107720276 non-coding downstream 434892 17488885 ~ 17494415 (-)
G37274 tomm22,LOC107554024,LOC107584213,LOC107692102 non-coding downstream 538886 17385841 ~ 17390421 (-)
G37254 tnrc6b,LOC107690060 non-coding downstream 591985 17335591 ~ 17337322 (-)
G37443 NA non-coding upstream 187449 18126534 ~ 18126807 (-)
G37444 NA non-coding upstream 188169 18127254 ~ 18127560 (-)
G37449 NA non-coding upstream 198864 18137949 ~ 18139122 (-)
G37450 NA non-coding upstream 201707 18140792 ~ 18141076 (-)
G37451 NA non-coding upstream 202922 18142007 ~ 18142377 (-)
vps25 vps25 other downstream 133319 17789951 ~ 17795988 (-)
cntd1 NA other downstream 224284 17692497 ~ 17705023 (-)
LOC103025753 LOC108425979,LOC108274047 other downstream 239923 17534703 ~ 17689384 (-)
LOC103025140 NA other downstream 452429 17473910 ~ 17476878 (-)
G37290 NA other downstream 463283 17432972 ~ 17466024 (-)
LOC103047479 LOC108441156 other upstream 343405 18282490 ~ 18317957 (-)
G37603 NA other upstream 633606 18572691 ~ 18573176 (-)
G37616 NA other upstream 694493 18633578 ~ 18635098 (-)
LOC103045068 antxrl,antxr1c,LOC108437311,LOC105893913,LOC106589351,LOC107720085 other upstream 1605140 19544225 ~ 19601284 (-)
c4h10orf128 NA other upstream 1879183 19818268 ~ 19825652 (-)

Expression



Co-expression Network