mstn (mstn)


Basic Information

Item Value
gene id mstn
gene name mstn
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035915.1
NCBI id CM008318.1
chromosome length 35429340
location 4756744 ~ 4760314 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007253246.3
CCGGACTCCAGCACCGTGGGTTGCAGTATAAAAATGCCTGGCGGGTTTAAAGCATGCCACCTACCTGCTGGTGCCCTGGTGCATGGCGCACTGCGCGTTCGCGactaaaaagagcaaaaaaaggaaaaaagcaaGCAGCCGTGAATCCCCCCTCCGCGCCTCGGACCATGCATCTCGCGCAGGTTTTGATCGCTCTCAGCTTCGTGCTCGCGCTCGGTCCAACGGTGGACAGTGAGCTCGCGGGAGCGCAGCCGcagccacagcagcagcagccgcagcaacaacagcagcagcagcagcagcagccggcAGCCGCGCGCACCGAGGAGGAGAGCGAGGCGCACTGCTCCACGTGCGAGTTCAGGCAGCACAGCAAAATGATGCGCCTCCACGCCATCAAGTCCCAGATCCTGAGCAAGCTGCGCCTCAAACAGGCTCCCAACATCAGCCGGGACGTGGTGAAGCAGCTGCTGCCCAAAGCGCCGCCGCTGCAGCAGCTGCTGGACCAGTACGACGTGCTGGGGGACGACTGCAAGGACGGGGTGATCGAGGACGGGGACGACGACGACCACGCCACGACGGAGACTGTCATGACCATGGCTTCGGAGCCTGACCCCATCGTCCAGGTAGATCGCAAACCCAAATGCTGCTTCTTCTCCTTCAGTCCAAAGATCCAAACGAATCGCATCGTGAGGGCACAGCTGTGGGTGCATCTGCGAGCCGTGGAGGAAGCTACCACCGTCTTCCTGCAGATCTCCCGCCTGATGCCCGTTACAGATGGAAGGAGGCAAATAAGAATAAGGTCGCTGAAGATCGATGTGAAAGCCGGGGTCACGTCTTGGCAGAGCATCGATGTAAAGCAGGTGCTCACCGTGTGGCTGAGGCAGCCGGAGACAAACTGGGGGATAGAGATAAATGCCTACGACGCTAAAGGAAACGACTTGGCTGTCACCTCGCCAGATGTGGGCGACGAGGGACTGCTCCCCTTCATGGAGGTGAAAATCTCAGAGGGTCCCAAGCGCTCCAGGAGAGATTCGGGACTGGACTGTGACGAGAACTCGTCCGAGTCGCGCTGTTGTCGGTACCCCCTCACGGTGGACTTTGAAGACTTTGGCTGGGACTGGATTATTGCCCCGAAACGCTACAAAGCCAATTACTGCTCGGGGGAGTGTGATTACATGCACCTGCAGAAGTACCCACACACCCACCTGGTGAACAAGGCCAACCCCCGTGGCACAGCCGGCCCATGCTGCACCCCCACCAAGATGTCGCCCATCAACATGCTTTACTTCAACGGCAAAGAGCAGATCATCTACGGCAAGCTCCCCTCCATGGTGGTGGACCGCTGCGGCTGCTCGTGAGGCCTTCCCCGAGGCAGGAGGACTCACTCGCTCCGTCTCAAAGCCCCCCTCTTCCCACCGGATCTCCCACAACCACAACACCCGTTGACCATTATCATCAGAGCTTTCTGCAGAAACAGATAAACACTGTGCAATAGAACCAGAATAGCAGCAAGGATGCTCATCCGTTCACCGAGCACCGCTTCACTCTCACCTCTCTGACTCGTTTTTCTTCATTATCCTAAATCTTTACGGCTCGGCCACAGCGGCCAGAGGTCACGTGGATATACACAAGGAGGAATGTCATGCTGGTTGGACTTGGGAAAGGACATCAAGCTTAAAAATTACAGCATTCTCTCATAACATCTTGTTCAATGTTATGATTTaaactgtctgtctctctctctctctctctctctctctctctttctctgtgtctctctctttgtcaaAACAGTCATCAACGCATATATAGGACAAACTCACACCTGGCACAAACATTGTATTACAGTAACATTTACAGTAACCTTCTCCACAACATCCATTCATTTAGTTCTCTTCTTGCTGCAACAGCTGTGCAACAGTATCAGTGAGCTTGTTTAAGTAAGGAATCCAAGAGCAACAGAGAGGGACTCAAGgacacttaaaacaaaaaaaaaaataaaaaaagaaacaaaagaagagGAAGCTTGAAAAAACCTGTCAGAAGAAACCAGTCTTTGTCTACAGTCAaaaccagaacacacacactgcacaatcTGATCTAATCGTTTAAATGTAGCTCTCTTTCCATTACTCAACTGTTCGAACTGCCCTATACACTTGAACTGTTATGAAAATCAGTATTACTGGACAGGAGGACTTGAACCAGTGGCACTTTGAATGCAGTCTATACATTGAAATGTGTTAAAGACAGAGAACTATTGAAAATAAGTATGAATGTTAATACCGCGTCACTTAACTCTGTCTTCAAACTACACAGTTTGCACTATGGCAGACCAATAGAAAGAATtggttgctaaaaaaaaatgttgtaaaaactGATTTTGATATGTTTGCTAATTGCATTGTATACTTGCCATTGTTTCCATTAACAGTTGCCTTTTTTAACCTCTGTTAGTTTGTGTATAAGACAGCACATTAGTGACAAATGTACAATATCAAATCTATGTATctgttaaaacaaataaaggtgcTTGCTTTATA

Function

symbol description
mstn Enables identical protein binding activity and signaling receptor binding activity. Involved in several processes, including muscle cell cellular homeostasis; negative regulation of protein kinase B signaling; and negative regulation of skeletal muscle tissue growth. Located in extracellular space. Implicated in myostatin-related muscle hypertrophy.

NR:

description
PREDICTED: growth/differentiation factor 8

GO: NA

KEGG:

id description
K05497 MSTN, GDF8; growth differentiation factor 8

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007253246.3 True 2546 mRNA 0.50 3 4756744 4760314

Neighbor

gene id symbol gene type direction distance location
hibch hibch coding upstream 22523 4671132 ~ 4734221 (+)
vwc2l vwc2l,LOC107660607 coding upstream 308124 4379022 ~ 4448620 (+)
LOC103033219 NA coding upstream 713151 4039986 ~ 4043593 (+)
cps1 cps1 coding upstream 1744854 2912007 ~ 3011890 (+)
map2 map2 coding upstream 1881678 2660455 ~ 2875066 (+)
ormdl1 ormdl1,LOC107602148 coding downstream 50234 4810548 ~ 4817692 (+)
osgepl1 osgepl1 coding downstream 61989 4822303 ~ 4827751 (+)
LOC103025618 LOC108436803 coding downstream 94089 4854403 ~ 4859014 (+)
slc40a1 slc40a1,LOC107660595,LOC107602151 coding downstream 112611 4872925 ~ 4887416 (+)
stat4 stat4 coding downstream 164744 4925058 ~ 4967478 (+)
G164952 NA non-coding upstream 20034 4698332 ~ 4736710 (+)
G164944 NA non-coding upstream 105851 4616803 ~ 4650893 (+)
G164910 NA non-coding upstream 253333 4501948 ~ 4503411 (+)
G164899 NA non-coding upstream 265035 4449979 ~ 4491709 (+)
G164907 NA non-coding upstream 301929 4452048 ~ 4454815 (+)
G164990 NA non-coding downstream 133831 4894145 ~ 4896061 (+)
G165013 NA non-coding downstream 256420 5016734 ~ 5056807 (+)
G165015 NA non-coding downstream 264940 5025254 ~ 5026263 (+)
G165034 NA non-coding downstream 356601 5116915 ~ 5117115 (+)
G165053 NA non-coding downstream 545428 5305742 ~ 5306443 (+)
G164539 spopl,LOC107751611,LOC108413068,LOC102233870 other upstream 2263753 2490044 ~ 2492991 (+)
LOC103028062 cunh3orf70,zgc:162707,LOC107668408,LOC107749877,LOC107752906,LOC107596553,LOC107592986 other upstream 2918657 1802787 ~ 1838087 (+)
tspear tspear other upstream 2996184 1744406 ~ 1760560 (+)
LOC103047444 myo10l3,LOC108413799,LOC102206624,LOC102799206,LOC101480403,LOC102301787,LOC107087138,LOC108240768,LOC107677785,LOC107752883 other upstream 3260364 1404101 ~ 1496380 (+)
G164126 NA other upstream 4184551 538279 ~ 572193 (+)
LOC103021746 LOC108436791,LOC107721608 other downstream 507725 5268039 ~ 5298728 (+)
LOC107196936 NA other downstream 1357050 6117364 ~ 6123051 (+)
G165406 NA other downstream 1384623 6144937 ~ 6145969 (+)
LOC111194881 NA other downstream 1400086 6160400 ~ 6237986 (+)
wdr4 wdr4 other downstream 1579681 6339995 ~ 6345403 (+)

Expression


Co-expression Network