Item | Value |
---|---|
gene id | LOC103028241 |
gene name | runx2b,runx2,LOC103028241,LOC108410521,LOC108258149,LOC107678859,LOC107726745 |
gene type | coding |
species | mexican tetra (Astyanax mexicanus) |
category of species | ornamental fish |
Item | Value |
---|---|
chromosome id | NC_035899.1 |
NCBI id | CM008302.1 |
chromosome length | 74127438 |
location | 44525886 ~ 44575275 (-) |
genome version | Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome |
symbol | description |
---|---|
runx2b | Enables DNA-binding transcription factor activity and vitamin D receptor binding activity. Acts upstream of or within chondrocyte differentiation; dorsal/ventral pattern formation; and positive regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including EVL; cranium; fin; osteoblast; and pharyngeal arch. Human ortholog(s) of this gene implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Orthologous to human RUNX2 (RUNX family transcription factor 2). |
runx2 | Enables sequence-specific double-stranded DNA binding activity. Involved in osteoblast differentiation; positive regulation of osteoblast differentiation; and regulation of transcription, DNA-templated. Located in nucleoplasm. Implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Biomarker of esophagus squamous cell carcinoma. |
description |
---|
runt-related transcription factor 2 isoform X1 |
id | name | namespace |
---|---|---|
GO:0002062 | chondrocyte differentiation | biological_process |
GO:0009953 | dorsal/ventral pattern formation | biological_process |
GO:0045893 | positive regulation of transcription, DNA-templated | biological_process |
GO:0005634 | nucleus | cellular_component |
GO:0005524 | ATP binding | molecular_function |
GO:0003677 | DNA binding | molecular_function |
GO:0042809 | vitamin D receptor binding | molecular_function |
GO:0003700 | DNA-binding transcription factor activity | molecular_function |
id | description |
---|---|
K09278 | RUNX2, AML3; runt-related transcription factor 2 |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
XM_007229717.2 | False | 4206 | mRNA | 0.45 | 7 | 44525886 | 44575272 |
XM_007229718.3 | True | 4572 | mRNA | 0.45 | 7 | 44525886 | 44574966 |
XM_022686636.1 | False | 4047 | mRNA | 0.44 | 6 | 44525886 | 44575275 |
XM_022686637.1 | False | 4120 | mRNA | 0.45 | 7 | 44525886 | 44575132 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
LOC103042571 | stmn4,LOC108439832,LOC108257558 | coding | downstream | 158046 | 44360099 ~ 44367840 (-) |
LOC103041948 | LOC108439850 | coding | downstream | 201429 | 44321703 ~ 44324457 (-) |
LOC103028959 | NA | coding | downstream | 208049 | 44311254 ~ 44317837 (-) |
LOC103040630 | znf395 | coding | downstream | 217188 | 44298947 ~ 44308698 (-) |
LOC103039281 | si:ch211-63o20.7,LOC108439852,LOC108258100,LOC107732427,LOC107726431,LOC107698369 | coding | downstream | 262693 | 44256451 ~ 44263193 (-) |
mut | mut,LOC107726757,LOC107697172,LOC107726528 | coding | upstream | 161892 | 44737167 ~ 44760205 (-) |
LOC103027014 | mfsd2b,si:dkeyp-115a10.3,LOC107750078,LOC107697177 | coding | upstream | 233551 | 44808826 ~ 44851093 (-) |
klhl29 | klhl29,LOC107667613,LOC107742703,LOC107697176 | coding | upstream | 407969 | 44983244 ~ 45315255 (-) |
trib2 | trib2,LOC107742704,LOC107667617,LOC107717709,LOC107697179 | coding | upstream | 783635 | 45358910 ~ 45365846 (-) |
LOC103023605 | napb,LOC106610947,LOC106599679,LOC103023605,LOC108411873,LOC108258064,LOC107756672,LOC107742707,LOC107593246,LOC107667620 | coding | upstream | 866163 | 45441438 ~ 45448166 (-) |
G26158 | cdc42bpb,LOC106607646 | non-coding | downstream | 80924 | 44441661 ~ 44444962 (-) |
G26154 | NA | non-coding | downstream | 148359 | 44377323 ~ 44377527 (-) |
G26084 | elp3,LOC107732362,LOC107698368,LOC107553498,LOC107696156,LOC107599080 | non-coding | downstream | 301613 | 44221013 ~ 44224273 (-) |
G26083 | NA | non-coding | downstream | 327408 | 44195249 ~ 44198478 (-) |
G26038 | NA | non-coding | downstream | 469587 | 44054940 ~ 44056299 (-) |
LOC111197214 | NA | non-coding | upstream | 38935 | 44614210 ~ 44615581 (-) |
G26238 | NA | non-coding | upstream | 107913 | 44683188 ~ 44688822 (-) |
G26240 | NA | non-coding | upstream | 123136 | 44698411 ~ 44698915 (-) |
G26278 | NA | non-coding | upstream | 277793 | 44853068 ~ 44853571 (-) |
G26290 | NA | non-coding | upstream | 286909 | 44862184 ~ 44865066 (-) |
cbr4 | cbr4,LOC107597475,LOC107665353 | other | downstream | 626126 | 43890629 ~ 43899760 (-) |
G25967 | mcm3l,LOC108416133,LOC108258154,LOC107697457 | other | downstream | 847024 | 43675025 ~ 43678862 (-) |
LOC103027084 | LOC108416115,LOC103358919 | other | downstream | 1008729 | 43495419 ~ 43517157 (-) |
G25785 | NA | other | downstream | 1414485 | 43098822 ~ 43111401 (-) |
G25678 | NA | other | downstream | 1807497 | 42717666 ~ 42718389 (-) |
fkbp1b | fkbp1b | other | upstream | 193989 | 44769264 ~ 44799505 (-) |
ubxn2a | ubxn2a,LOC107603085,LOC107750080,LOC107697178 | other | upstream | 280824 | 44856099 ~ 44870690 (-) |
G26295 | atad2b,LOC107697175,LOC107603081 | other | upstream | 307503 | 44882778 ~ 44885801 (-) |
G26388 | NA | other | upstream | 860834 | 45436109 ~ 45437585 (-) |
G26588 | NA | other | upstream | 1359878 | 45935153 ~ 45935622 (-) |