cryab (cryab,LOC108259721)


Basic Information

Item Value
gene id cryab
gene name cryab,LOC108259721
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035899.1
NCBI id CM008302.1
chromosome length 74127438
location 1437806 ~ 1442109 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007245217.2
AGTGGGATGAGACAGCTTGCAGAGGAGAGTGGGAGGGACGCAACGAAAGGGGGGCCATCAAACAGTTTACATCATTGTTCCAGAAAGATCCGCAGCTGGCTGGGCCTGGCTCTGTGACCGCTACTGGTGGTGTATATAAGTGGGCAGGCTGGGCAGACAACAGGTTTTTCTCCAGGAGGACAACGCTAGCCTTAGGTCAGAAGACGAAATGGACGTCGCCATCCAGCATCCCTGGTTCCGCCGCTCTTTCTGGCCATCCTTCTTCCCCAGCCGGATCTTCGACCAGCATTTCGGGGAGCATATCCCAGAGAGTGAGATGTTGACCCCCTACCCCTCATTGTATTACCCACGACCCTCTTTCTTCCGCTTACCTAGTTGGGTGGAAAGTGGGCTATCAGAGATGAAAATGGAAAAGGACCGTTTTACCATCAATTTGGATGTAAAACACTTTGCACCTGAGGAATTGGCAGTTAAGGTCAACGGCGGTTACATTGAGGTTCATGCTAAACACGAGGATCGTCAgGATGACCATGGGTTTGTCTCACGAGAGTTCCTACGAAAATACCGGCTCCCTCTCGGGGTCGACCCAGCCAGTATCAcctcttcactctcttcagATGGCATCCTCATGGTTGCAGCCCCTCGCAAGCTCTCCGATGAGCCTGAGCGCTCCATTCCCATCACTCGAGAAGAAAAGCCTGCTATCTCTGGCTCACAGAAAAAGTAAAGCTGCTAGATACTTGCTCCTTTCTGTCTCCCCTCCGCTGTGGTCCCCCTGCACTTATCTTCCACCTTCACATCCCAAGTCAAGCTTTGAGGAAAAGCCAGTGCTAGCATTGAGCTGAACCTTCTAGAGGCTTGGCCTTTCCAGAGGCTAGTCCTAATCAAAGGGCTCATTTCTGAGCTAGCTAGTAACTGTTCTAGCACATGTTTCTGTGCTAAATAGTGATCACTGAATTGTCTAATTCGGTTGGCACATCAAAACCGTGTCCTCAGAGATATGTACATCATTACACCACAGGAGTATTGTTTGTGCCGCTCAGCCGCTGGACGCAAAACACATTTTGCTTCAGCAATCCCAACCACAACCACGCCAAACAAAAGTGCTCTTTGTCTTTTACAGCCAGTCAGTGGCAAACAATGGTGGCACGGAGTAGAGAATGGTGAGGGATTGAGTGTAGGAAGACTGGATGTTCGAGCATTTTTGTGATCAAGCGGTGAAAAGAAATTAGCCTACGAGGAAGAACACTGTGAGGGAATTTTCATTGAGgtaaaaaatgttgtttgtttggtttcaaACGTTTCATGTGAAGTGGGAGGTGGTGTGCCGAGAAAAAATGAGTATGTTTCGTAATTTGAAAAAAACTTCCTTTTCATGATGGACTTGGGACCAGATGATACATGAAGATCAAGTGCAGGTAGCAACAAGGTGAGGAGAAATGTTATAGAAAGAAAGTGACCTCTTTTTTTTGGTAGTTTCTGTGGGATTCTGTAGACATGACTTTTCATTGGTTTGGATGGATTGATATATGGCGTCTGGAAACATCTTGTTATAAATGGAGCAGTGAATCAAATATGATGAGGTTTGGTTTGATATTGAAAAGCTGCGTTCCAAAGTCTAGATTGGCTCCATTTCTCAGCCACTTTGTCATAAAAGCCTGTCATAAGTGAAGGGCTCTTATTATACAGCCTACAGCTGAGAAATGCAGTCAGGGTTTGGAGCAATAGACCTTGGAGTgcagatagaaaaaaaatgggGATGTGGGAATTTGGTGGAAGAGATTATAATTAGTTAAAAATTATTCAGAGGTGTTTGGATTTCCTAAAGAATGTGTCTGCTGactttttcacatattttaatgtgtttcaaTCAAGTATTTGCTCATAttctacataaaatatataatactacattttgcaaacaataaaaaagagattGGAGGTTGTTTACTATCTATAATAGCCATCTATTTTACAGCAATGCTCCCAAAAGcagacatcccacctctccCTTACCTCCCGGGATTCTCACACATACAAGGCATTAACTTGTTGAAATTAGTTTTTACAGGGCAGATTGTCTGCAAAAATATTATTGAGAAAGCTGCTTCAATAAGAAATGATGTGATGTTGTAACAAGGCACACAACGTAATACACTTTTGGAAACACTTTCTTTGTGCAAAGGTAAATGTGGACCACAGTTATTATATCAACTAAAAGGCACAAGTGAGGGGGACACACAAGTAGCTGTTTCATGTGTTCTTGGTTAGGATTGGTCTTTTACATTGTCCTGGGGTTAaaactgcttttaaacattCTACAAGGTTCTTTAACTAATACCATAGAACAGTGATGTATAGTCTATTCCACTCTCAGATTTTCATTCTAACCAACCAGCAGCacaattaataaactcatgAGTTTTTTCAGGAACTGATAATGTGCTTCTGCTTGTCTGAAATGAAAACGAAAAAAGCCACACTTGCCTTTTTCAGATAAGGCTGGACACCACTCTCATAGAAGAACCCTTTTTTACTTCCCTAAAGAACCATATTTGTATAAGAGACCCTATAAACACGTAAATATCCTTTgctttaaaaggttctttaccaatataaaggttcttcacactcacatTTCTTCAACAAATATTCTTTGGGGAAACAAAAATGAGCTTGGCTCCAAGAacctttgtagcacctttatgtTTAAGAGTGTAAAATAAGAACAAACAGGTCTCAGATCAGTGTAAAAGGCTCAGTGTTCCAGTCTTCTGCTGTTTCTGTTCACTGCTTCAACATTCCTTGTGATTCATGGCACTAAAACAATGTGTAAACACCACTtctccatgtgtgtgtaatgatggtTATAAACATCCAATAAATTCTGTGATCATTCAAAGATTCA

Function

symbol description
cryab Enables several functions, including amyloid-beta binding activity; protein homodimerization activity; and unfolded protein binding activity. Involved in several processes, including negative regulation of cellular component organization; negative regulation of transcription, DNA-templated; and protein stabilization. Acts upstream of or within cellular response to gamma radiation and regulation of cell death. Located in cytoplasm and nucleus. Part of protein-containing complex. Implicated in cataract 16 multiple types; dilated cardiomyopathy 1II; fatal infantile hypertonic myofibrillar myopathy; and myofibrillar myopathy 2.

NR:

description
alpha-crystallin B chain

GO:

id name namespace
GO:0005212 structural constituent of eye lens molecular_function
GO:0051082 unfolded protein binding molecular_function

KEGG:

id description
K09542 CRYAB; crystallin, alpha B

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007245217.2 True 2908 mRNA 0.42 3 1437806 1442109

Neighbor

gene id symbol gene type direction distance location
LOC111191737 NA coding upstream 828377 600428 ~ 609429 (+)
LOC103023152 NA coding upstream 879404 551043 ~ 558402 (+)
LOC103028849 NA coding upstream 913668 509572 ~ 524138 (+)
LOC107196798 NA coding upstream 943437 483139 ~ 494369 (+)
LOC107197531 NA coding upstream 969722 448393 ~ 468084 (+)
LOC103029064 LOC103029064,LOC108428730 coding downstream 15361 1457470 ~ 1469889 (+)
ufc1 ufc1,LOC107574697,LOC107691797,LOC107603203 coding downstream 55599 1497708 ~ 1500545 (+)
alg9 alg9,LOC107691744 coding downstream 91920 1534029 ~ 1549757 (+)
LOC103032850 ppp2r1a,LOC103032850,LOC108428700,LOC108260120,LOC107691746,LOC107745127,LOC107603174,LOC107663771 coding downstream 117740 1559849 ~ 1579498 (+)
btg4 btg4 coding downstream 222487 1664596 ~ 1669346 (+)
G15749 NA non-coding upstream 16998 1415182 ~ 1420808 (+)
G15748 NA non-coding upstream 25237 1409933 ~ 1412569 (+)
G15724 NA non-coding upstream 732004 686073 ~ 705802 (+)
LOC111194479 NA non-coding upstream 822567 613037 ~ 615239 (+)
LOC111194483 NA non-coding upstream 840076 593655 ~ 597730 (+)
G15771 NA non-coding downstream 12218 1454327 ~ 1457428 (+)
G15813 NA non-coding downstream 139404 1581513 ~ 1581946 (+)
G15818 NA non-coding downstream 144669 1586778 ~ 1636251 (+)
G15831 NA non-coding downstream 181817 1623926 ~ 1624377 (+)
G15845 NA non-coding downstream 287721 1729830 ~ 1730349 (+)
LOC103025578 NA other upstream 97006 1322516 ~ 1340800 (+)
LOC103031762 gnb2,LOC108428986,LOC107663406,LOC105023919 other upstream 1316625 70784 ~ 121181 (+)
fdxacb1 fdxacb1 other downstream 74388 1516497 ~ 1529417 (+)
G15839 NA other downstream 239050 1681159 ~ 1682022 (+)
nrgn NA other downstream 708521 2150630 ~ 2171207 (+)
LOC103038305 NA other downstream 3073888 4515997 ~ 4517309 (+)
LOC103025913 NA other downstream 4726651 6168760 ~ 6177884 (+)

Expression


Co-expression Network