dtl (dtl)


Basic Information

Item Value
gene id dtl
gene name dtl
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035899.1
NCBI id CM008302.1
chromosome length 74127438
location 31598684 ~ 31608806 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007255496.3
TGGCTTTGTGCTTCAGTTCGCGGGAAGCGGTGGGCAGCGGGATCTCAGTAGTTTTTAGGTTAAGATTGGAAAAATAAGCTTTAAAGTGTGAAGATCTTTATATCACTATGCTGTTTCAGTGCGTGGTTGACCGGGGAGTGACCAGGAGGAGAAACGttaacAGACAAGAATATCCAGTATCGTCTCTGCTGGAGTGTTATCAGTGCACTCGTCATGATGAACACATCTCATACGGAAACACTGCAGTTGCTGTTCCTCCATTTGGATGTTCATTTTCCACAGCTCCTGGACAGCACAACACTCTGGCAGTTGCGAATGAGGAGGGTGTTGTGGCCATCTATAAAACTGCTGAGAAACAAAGCTCAGTCCTAAAGGAATGGCCTGCACATGATAATGCTGTGTTTGATATTGCCTGGGTCCCTGGAGCGAACAGCTTGgtGACTGCATCCGGGGATCAGACGGCACGTTTGTGGGACGTGCTTGCAGAGGAGCTTCTAGGCAGCTTTAAGGGTCACCAGTGCAGCCTGAAGTCTGTGTCTTTCCCGAAACAAGAGAAAGctgtattcTGCACAGGAGGCAGGGACGGTAACATCATGGTGTGGGATACAAGGTGTAGTAAAAAAGATGGTTTCTACAGGCAGGTGAAGCAGATCAGTGGAGCTCACATGAAGACAGCAGGAAACACACCCCAGAACAAGAAGAAACGTTCTTCATGCAGAGGAATGGCTCCTTCTGTGGACTCTCAGAGGGGTGTGACTGTAGTTCTTTTTCGTGATGAAAACACGCTCATCTCTTCAGGAGCTGTAGACgggaTGATTAAAATGTGGGATTTGCGTAAAAACTACACTGCTTATCACCAGAACCCCATTCCTCTGCAGACGTATAAATACCCCGGCTCCAGCACCCGCAAATTAGGTTATTCAGGCCTAACGTTGGACTCCACAGGCTCCAGGCTGTTCTGCAACTGCACAGATGACAATGTGTACATGTTTGACATTAGTGGACTGAAAACAACACCAGTGGCTGTGTTCAGCGGTCATCGTAACTCCTCTTTCTACGTGAAGTCCAGCCTCAGTCCAGATGATCAGTTCCTGGCCAGCGGCTCCACCGACTGCAGTGCCTACATCTGGAAGATCTCTGAACCAGCAAAAGCTCCAGTAATGCTGCAGGGACATAGCCAGGAGGTGACCTCAGTCACGTGGTGTCCCACTGATTTCACAAAGCTTGTTACCTGCTCAGATGACAACACAGTCCGAATATGGCGTCTTAACCGAGGTGCCGAAGGAGAAAAGTCTTCTGTTGGAGAAGCTAATCTTGTAGGCTGGGCACGACGCAAAGTTCAGACACCTTCTAAGCCATCAGGCCATTTTACTCATGTGGAGCTCACCCCTGCCCGGGTCTCTAGCATGGTCCGTGTGAATGGTTTGGCTTCTCCTCAGCCTGGATCCTGTCCCTCCAGCGATGCTGATTTGCCTCCAGCGTCCAGCAGCTCCGAACCCAAACACAGCCCTGCACACCCCAAAACCCCTAAAACCCCCCGGACCCCATCCTCAATCCGGCAGTGGGTCTCCCGTACGCCTGGTTCTCACTGTAACCACACCACGCCTCCTCTCCGGAAGGTTCTAAGCCCGTGTCCACAGAGTCCTGAGCGTGTTTCTCCATCTGAGCGGAAGGCCAAGCGGCGTCTGGAGACGGGCGACAGCTCTCTAAGTCACCATGATAACAGCGACGGAGTGGCCGAGCTTTGGCCGGAAGCCAAAAGGAGCCGGGTGTCAAAAGGAACTTTTGACAATGAAGCAAAGGAGGAAGAGGGTAAATCTGAGATTTCTGAGACAAAGAACAAGCCGCTAACATTACAAGTACAAGCAGATAAAGAGAACAGCTCACCATCCAAACCTGACTGGCTCTCCGCGATGAGCCACAGACTTAAACAAGCTCAGAAAGGACCGCTTTTATCCAAAAGCCCAAATGGGGGCAAGAGACTCGATTCCAGGACACAGTCTGCTTCTgCTTTAGGTTCTCCACATTCTATGAGGAAGATCTCTTCTCCACAACCTCAGAAAACTTCTTCTCCACGTTCTATGAAAAAGATCTCTTCATACTTTCAGAAAACACCACAAAAATGATCTCCTTCTGCAAGGAAAATTTCCAGCCTTTTTCCAGACTTTTAATTACCATCACTATCTTTCTGAAACAGCAGAGATGAAAATacagtttagtttgtttaaagATGCGTTTTTTAAGAGAAACATGCTCCACTGCATGTGTTGTATATTTTAGCCTCTCTTTAAATCTGAGGTGTATTTTCATGTAAATAGACaaattatcttattattaaatgacTGTACTTTTAGCTGTACAGCTTCACAGAAAAGAATGTTGTTTTCAGTTCTAACTGTATGTTCACTAATGTTTAATGCaagtgtgttaagtgtgtgaaACACAGAATTCTGCTATTGCTTTTGTATATGTACATAAAACTgtcctgtttatttttattcttattttttattcctgTTGGCTGCTATTTTCTTAACTGGTGTTGAATTAAATGAAGACACAGGGTCTGAAATGATGTTTCCACACTGACTTTCCTGGTACTGTAGCTTGCACTCATACATAGAATTCAGAATAGGCTTTACATTTTAATCTGCTCATTTACACG

Function

symbol description
dtl Predicted to contribute to ubiquitin-protein transferase activity. Acts upstream of or within mitotic G2 DNA damage checkpoint signaling. Predicted to be located in centrosome and nucleus. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and Cul4B-RING E3 ubiquitin ligase complex. Is expressed in several structures, including central nervous system; immature eye; mesoderm; optic primordium; and tail bud. Orthologous to human DTL (denticleless E3 ubiquitin protein ligase homolog).

NR:

description
denticleless protein homolog

GO:

id name namespace
GO:0009411 response to UV biological_process
GO:0006511 ubiquitin-dependent protein catabolic process biological_process
GO:0006513 protein monoubiquitination biological_process
GO:0000209 protein polyubiquitination biological_process
GO:0007095 mitotic G2 DNA damage checkpoint biological_process
GO:0019985 translesion synthesis biological_process
GO:0005813 centrosome cellular_component
GO:0005634 nucleus cellular_component
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex cellular_component
GO:0031465 Cul4B-RING E3 ubiquitin ligase complex cellular_component
GO:0004842 ubiquitin-protein transferase activity molecular_function

KEGG:

id description
K11790 DTL, CDT2, DCAF2; denticleless

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007255496.3 True 2665 mRNA 0.46 15 31598684 31608806

Neighbor

gene id symbol gene type direction distance location
LOC103025325 NA coding upstream 164471 31427579 ~ 31434213 (+)
rhag rhag,LOC107549521,LOC107695981 coding upstream 180567 31398412 ~ 31418117 (+)
c3h12orf57 grcc10,clg18h12orf57,cssa15h12orf57,c25h12orf57,c7h12orf57,LOC103027128,LOC107695984,LOC105901913 coding upstream 417570 31175441 ~ 31181114 (+)
LOC103028275 ppp1cb,LOC107583611,LOC108426284,LOC107582864 coding upstream 436036 31150426 ~ 31162648 (+)
plb1 NA coding upstream 449507 31121395 ~ 31149177 (+)
ppp2r5a ppp2r5a coding downstream 3707 31612513 ~ 31658213 (+)
LOC103022697 NA coding downstream 56296 31665102 ~ 31691430 (+)
rnf8 rnf8 coding downstream 98248 31707054 ~ 31713807 (+)
tcte1 NA coding downstream 114199 31723005 ~ 31728361 (+)
nfkbie NA coding downstream 141361 31750167 ~ 31759510 (+)
G22845 NA non-coding upstream 50584 31547750 ~ 31548100 (+)
G22844 NA non-coding upstream 51167 31547192 ~ 31547517 (+)
G22837 NA non-coding upstream 90775 31507450 ~ 31507909 (+)
G22835 nek2,LOC107549520,LOC106571199,LOC107695968 non-coding upstream 93333 31500015 ~ 31505351 (+)
G22822 slc30a1 non-coding upstream 118513 31395732 ~ 31480171 (+)
G22937 hsp90ab1,LOC106942468,LOC102219317 non-coding downstream 180866 31789672 ~ 31792894 (+)
G23022 NA non-coding downstream 747831 32356637 ~ 32357253 (+)
G23053 NA non-coding downstream 883449 32492255 ~ 32492741 (+)
G23057 NA non-coding downstream 913208 32522014 ~ 32527724 (+)
G23062 NA non-coding downstream 916256 32525062 ~ 32547464 (+)
G22834 NA other upstream 103786 31494345 ~ 31494898 (+)
LOC103026436 LOC108411506,LOC103368653 other upstream 1085858 30449364 ~ 30512826 (+)
LOC111195794 LOC107569315,LOC107712034,LOC107751710 other upstream 1334834 30259308 ~ 30263850 (+)
LOC103034207 ube2w,LOC107585923,LOC103354920 other upstream 2416553 29171008 ~ 29182131 (+)
pabpn1 pabpn1,LOC107596039 other upstream 2430771 29152052 ~ 29167913 (+)
G23086 cpsf2,LOC107704064,LOC107548411,LOC107559080,LOC107669458 other downstream 1213538 32822344 ~ 32826939 (+)
LOC103042732 NA other downstream 1228246 32837052 ~ 32841346 (+)
LOC103037425 LOC108426312 other downstream 1467818 33076624 ~ 33081862 (+)
LOC103036694 LOC108426313,LOC108257731 other downstream 1474836 33083642 ~ 33169392 (+)
LOC107197779 LOC107197779,LOC108426271,LOC106607680,LOC108257511 other downstream 1978723 33587529 ~ 33595711 (+)

Expression


Co-expression Network