hdac2 (hdac2,LOC108416127)


Basic Information

Item Value
gene id hdac2
gene name hdac2,LOC108416127
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035899.1
NCBI id CM008302.1
chromosome length 74127438
location 38428649 ~ 38438064 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007259908.3
AGGCCCcgcctcctccttctcctccgtCTCCGTGCTCCTCATCAGCTCTGTAGTTACCTGTCTCTCTCCGCAGCTCCTGCTAGattttaatctgtatttaaTCTAATCAGCGCGCTCTGGTCGCGGGGATCGTGTGTGTGGAGCATGGCGTTCACTCTGCAGGGCACCAAGAAGAAAGTCTGCTATTATTATGACGgtgATATTGGGAATTACTACTACGGTCAAGGCCACCCTATGAAACCCCACCGTATTCGCATGACTCACAACCTCCTGCTGAACTATGGTCTCTACCGCAAGATGGAGATTTATcGTCCCCATAAAGCCACAGCTGATGAGATGACGAAGTACCACAGTGACGATTATATAAAGTTTCTGCGCTCCATCCGACCTGACAACATGTCCGAATTCAGCAAGCAGATGCAGCGCTTTAATGTAGGGGAGGACTGTCCGGTGTTTGATGGGCTGTTTGAGTTCTGTCAGCTCTCTACAGGAGGATCAGCAGctGGTGCTGTAAAGCTGAATAGGCAGCAAACGGATATTGCTGTAAATTGGGCAGGTGGACTGCACCACGCTAAGAAATCAGAGGCATCGGGTTTCTGCTACGTAAACGACATTGTACTGGCCATCCTGGAACTGCTGAaGTACCACCAAAGGGTGctgtatattgatattgatattcaTCATGGCGACGGGGTGGAAGAGGCTTTCTACACCACTGACCGCGTGATGACTGTCTCCTTCCACAAATATGGAGAATACTTTCCCGGAACTGGAGACCTGCGGGATATCGGAGCAGGCAAAGGGAAATACTATGCCGTTAATTTTCCTCTGAGAGACGGAATTGATGACGAGTCATATGAGCAGATCTTCAAGCCGgtaatGGCTAAAGTGATGGAGATGTATCAGCCCAGCGCTGTGGTTCTGCAGTGTGGAGCAGATTCCCTTTCTGGTGACCGACTGGGCTGCTTCAACCTCACTATCCGTGGTCATGCCAAATGTGTAGAGTACATGAAGTCGTTTAATCTGCCGCTGCTGATGCTGGGAGGGGGAGGGTACACTATTCGTAACGTGGCACGCTGCTGGACCTACGAGACTGCTGTGGCTCTCGACACAGACATCCCTGATGAGCTGCCATATAATGACTACTTTGAGTACTTTGGGCCAGACTTTAAACTGCACATCAGCCCATCCAACATGACCAACCAGAACACACAGGAGTACATGGACAAGATCAAGCAGAGGTTATTTGAGAATCTGCGGATGCTGCCACATGCTCCCGGGGTTCAGATGCAGGCCATTCCAGAGGATAGCCTTCCAGACGATACGGTGGATGAGGACACTGAGGATCCAGACAAACGCATGTCCAtccgTGCATCTGATAAGAGGATAGCATGTGATGAAGAGTTCTCGGACTCTGAGGATGAGGGAGAAGGTGGGAGGAGGAATGTGACCAATCACAAGAAAGGAGCCAAACGAGCTCGAGTGGAGGACGAGAAGAAGGagggagaagaaaagaaaactgaggtaaaggaggaggagaagtcTAAGGAGAGCAGCTCGGAAAAACACGAGTCTAAAAGtgtGAAGACTGACCAGACAAGCAGCACCTGAAACCACCACCAGAGGGTGCACAGATGTGTctgtttatctctgtctctgtttctctctctctctctctctctccctctctctctttctctcagcacCCCAACCACACCCCACACCCCTCCACCGGACTACACACTCATTAGCATTATATTTATtacccagtgtgtgtgtgtgcgcgagcgtgcatgtctgtctgtgtgagtgggtggatgggtgtgtgtgtgtgtgcttgtgtttttCATCTTTCTGATCCAGTTCTGTGTCCAGATGTTTTTCAATAACCATGTAGGAGTCCCTCCAGATCAGCAGGGGTGCttatgtctttgttttttatttttaatagaacGTTTGTACTGATATTTTAGAAAATATGTGGATGTTCATTTTGAAAACACATGGTGACTATTTCAAATTTCTTTAAATTGCATATTTTGTATTTGCATATTAAACTGTTTTATACTA

Function

symbol description
hdac2 Enables several functions, including NF-kappaB binding activity; histone deacetylase activity; and histone deacetylase binding activity. Contributes to nucleosomal DNA binding activity. Involved in several processes, including histone deacetylation; positive regulation of proteolysis; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleoplasm. Part of ESC/E(Z) complex; NuRD complex; and Sin3 complex. Implicated in stomach cancer. Biomarker of several diseases, including autoimmune disease (multiple); cervix uteri carcinoma in situ; gastrointestinal system cancer (multiple); prostate carcinoma; and pulmonary hypertension.

NR:

description
histone deacetylase 2

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0070932 histone H3 deacetylation biological_process
GO:0070933 histone H4 deacetylation biological_process
GO:0005634 nucleus cellular_component
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) molecular_function
GO:0097372 NAD-dependent histone deacetylase activity (H3-K18 specific) molecular_function
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific) molecular_function
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific) molecular_function

KEGG:

id description
K06067 HDAC1_2; histone deacetylase 1/2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007259908.3 True 2070 mRNA 0.48 14 38428649 38438064

Neighbor

gene id symbol gene type direction distance location
hs3st5 hs3st5 coding upstream 731 38416750 ~ 38427918 (+)
LOC103029663 NA coding upstream 28328 38381590 ~ 38400321 (+)
col10a1 col10a1,col10a1b,LOC108415286,LOC107548284,LOC107704357,LOC107710900 coding upstream 78325 38344389 ~ 38350324 (+)
LOC103045011 LOC103045011,LOC108414810 coding upstream 439716 37984712 ~ 37988933 (+)
LOC103046026 cx27.5,LOC108414812,LOC107597344,LOC107687661,LOC107680359,LOC107592389,LOC107732608 coding upstream 453390 37969234 ~ 37975259 (+)
lama4 NA coding downstream 88514 38526578 ~ 38577159 (+)
tube1 tube1 coding downstream 141899 38579963 ~ 38606640 (+)
LOC103028301 LOC108415536,LOC107709524 coding downstream 207267 38645331 ~ 38662640 (+)
LOC111191700 LOC108415880 coding downstream 283613 38721677 ~ 38726048 (+)
traf3ip2 LOC107550525 coding downstream 291248 38729312 ~ 38742584 (+)
G24437 ufl1 non-coding upstream 169400 38256201 ~ 38259249 (+)
G24432 NA non-coding upstream 182360 38243485 ~ 38246289 (+)
G24359 NA non-coding upstream 391901 38027773 ~ 38036748 (+)
G24340 fam76b,fa76b,LOC107680374,LOC107687655,LOC107592275,LOC106603374 non-coding upstream 484715 37938839 ~ 37943934 (+)
G24341 LOC108415597 non-coding upstream 518126 37906277 ~ 37910523 (+)
G24474 NA non-coding downstream 2288 38440352 ~ 38440660 (+)
G24476 NA non-coding downstream 11931 38449995 ~ 38492705 (+)
G24485 NA non-coding downstream 65163 38503227 ~ 38503518 (+)
G24531 NA non-coding downstream 143563 38581627 ~ 38582793 (+)
G24535 NA non-coding downstream 152877 38590941 ~ 38592527 (+)
G24463 NA other upstream 46339 38359335 ~ 38382310 (+)
LOC111191729 LOC108416192 other upstream 49313 38359460 ~ 38379336 (+)
G24431 NA other upstream 191608 38232593 ~ 38237041 (+)
G24390 NA other upstream 330325 38092974 ~ 38098324 (+)
G24345 cwc15,LOC107747811,LOC107597228,LOC107732607 other upstream 494660 37928355 ~ 37933989 (+)
G24534 NA other downstream 147375 38585439 ~ 38586278 (+)
fyn fynb,fyn,LOC107704353,LOC103458010 other downstream 229445 38667509 ~ 38717435 (+)
G24594 smim8 other downstream 487632 38925696 ~ 38926982 (+)
G24583 NA other downstream 501293 38939357 ~ 38947222 (+)
G24719 NA other downstream 607106 39045170 ~ 39045781 (+)

Expression


Co-expression Network