eif2b4 (eif2b4)



Basic Information


Item Value
gene id eif2b4
gene name eif2b4
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035899.1
NCBI id CM008302.1
chromosome length 74127438
location 59562829 ~ 59573611 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_022663821.1
GCGGTGCTTCTCCTGAGCACATCTCTTCTGAACCCTCAACGTGATGTCCAGCAAGTGGAAACATGGCAGATTCAGAGGGAAACGAGCGCTCTAAACAGACAGCCATCATCAACCACGCTGCAGATGAAGGAGATGAGAAGTCTCTTGCTGAAATTCAGAAAGCAAAGaATGAAGGTAAGGAGctgacaaaagaagaaaaactacGTCTGAGGAAAGAgaagaaacaacagaaaaaggGCAAGAAAGATGACAAGGGTCCAACGGAAAAAGCGcctgttaaagaaaaaacagcaaatccTCCAGCTTCCTCTCAACCAGTTACGCAAAATGCAGCACAGAAAGCCCCATCTGCAGTGTCTGTGCCGGTCAGTGAGTCCACTGCACCTACAGACAAGTCAGCTAAGAGCAAAGCAGAGTTGAAGGCTGAGAGGCGAGCACGCCAAGAAGCGGAACGGGCATCAAAACAGGCCAAGAAAGAGCCAGGTTCACAAGCCCCCTCCAGCAAGTCGAAAGCTCCGCCGAGTGAGCTCCAGCCAGCGGTAAAACGATTACCGGAGCATATCCAAGTGGACGATCCAGCTGTGGTGAGAAAACTTGCCAAGAAGCTGGAAAGACAACAGATCCCACTGAGGTCAGACTATGGCTACAAAGTCAGCCTGTTCTCGCACCTACACCAGTACAGCCGCAAAGCCCCCCTCACCCAGCAGATCAGCATTCCTGCCACAGTTATCCACCCCTCCATTGTGCGGTTGGGTCTGCAGTACTCACAGGGTATCGTAGCTGGTTCCAATGCTCGTTCTGTGGCCCTGCTGCATGCCTTTAAGCAGGTGATTCAAGACTACAGCACTCCTCCTAATGAGGAGCTGGCCAGGGACCTAGTGAATAAACTGAAGCCCTACATAAGTTTTCTCAATCAGTGTCGCCCTCTCTCTGCAAGCATGGGTAATGCAATCAAGTACATAAAGAAGGAGATCTCCAATATACCCAGTCAGTGTAAAGAAGAGGAGGCCAAGAAGAAACTGTTATCGTGTGTTGACAGCTATGTAAATGAGAAGATCACATTAGCCGCGAAAGGCATCTCTAAATATGCAATTGATAAGATTAGTGATGGAGACGTCATTCTAGTGTACGGATGCTCTTCACTAGTCAATCACATCCTGTGTGAGGCCTTTGAGAAGCAGAGGAAGTTCAGAGTCATTGTGGTGGACAGTCGGCCCAGGCTGGAGGGCAGGGAAGCACTGAGGCGTTTGGTGAACCGGGGCATACGATGTACTTACGTGCTCATTTCTGCCGTCTCCTATGTTCTGCCTGAGGTATCCAAGGTGTTTCTTGGGGCTCATGCACTTCTGGCCAACGGATACGTGATGTCCCGTGTGGGAACGTCTCAAATCGCCCTGGTGGCAAAGGCCTATAATGTGCCTGTGCTGGTCTGCTGTGAGACCTACAAGTTCTGTGAACGAGTGCAGACGGATTCCTTCGTATCTAATGAACTTGATGACCCTGACGACCTGATTGTGACTCGGAAGGGAAAGACACATCTGGCGGACTGGCAGAGCGAGACGTCCTTGGGCCTGCTGAACTTGGTGTATGATGTAACACCTCCAGACTTTGTTGACCTGGTGATCACAGAGTTAGGCATGATCCCCTGTACTTCTGTGCCTGTAGTACTACGAGTTAAGAACGTGGATCAGTAAAGAAAGCGGCTTCTGCTTTGCATTTGTGCATTCACAAACCTTAACACAGTGGGCTTTTGGCATAAAATAAACCTGTATCTAAAATGGCACATGCTTTTAAT
>XM_022663830.1
GGGCGGTGCTTCTCCTGAGCACATCTCTTCTGAACCCTCAACGTGATGTCCAGCAAGTGGAAACATGGCAGATTCAGAGGGAAACGAGCGCTCTAAACAGACAGCCATCATCAACCACGCTGCAGATGAAGGAGATGAGAAGTCTCTTGCTGAAATTCAGAAAGCAAAGaATGAAGGTAAGGAGctgacaaaagaagaaaaactacGTCTGAGGAAAGAgaagaaacaacagaaaaaggGCAAGAAAGATGACAAGGGTCCAACGGAAAAAGCGcctgttaaagaaaaaacagcaaatccTCCAGCTTCCTCTCAACCAGTTACGCAAAATGCAGCACAGAAAGCCCCATCTGCAGTGTCTGTGCCGGTCAGTGAGTCCACTGCACCTACAGACAAGTCAGCTAAGAGCAAAGCAGAGTTGAAGGCTGAGAGGCGAGCACGCCAAGAAGCGGAACGGGCATCAAAACAGGCCAAGAAAGAGCCAGGTTCACAAGCCCCCTCCAGCAAGTCGAAAGCTCCGCCGAGTGAGCTCCAGCCAGCGGTAAAACGATTACCGGAGCATATCCAAGTGGACGATCCAGCTGTGGTGAGAAAACTTGCCAAGAAGCTGGAAAGACAACAGAAGTCAGGGCAAGGAACCAGTTTAAATGTATCTCGAGTCAAGATCCCACTGAGGTCAGACTATGGCTACAAAGTCAGCCTGTTCTCGCACCTACACCAGTACAGCCGCAAAGCCCCCCTCACCCAGCAGATCAGCATTCCTGCCACAGTTATCCACCCCTCCATTGTGCGGTTGGGTCTGCAGTACTCACAGGGTATCGTAGCTGGTTCCAATGCTCGTTCTGTGGCCCTGCTGCATGCCTTTAAGCAGGTGATTCAAGACTACAGCACTCCTCCTAATGAGGAGCTGGCCAGGGACCTAGTGAATAAACTGAAGCCCTACATAAGTTTTCTCAATCAGTGTCGCCCTCTCTCTGCAAGCATGGGTAATGCAATCAAGTACATAAAGAAGGAGATCTCCAATATACCCAGTCAGTGTAAAGAAGAGGAGGCCAAGAAGAAACTGTTATCGTGTGTTGACAGCTATGTAAATGAGAAGATCACATTAGCCGCGAAAGGCATCTCTAAATATGCAATTGATAAGATTAGTGATGGAGACGTCATTCTAGTGTACGGATGCTCTTCACTAGTCAATCACATCCTGTGTGAGGCCTTTGAGAAGCAGAGGAAGTTCAGAGTCATTGTGGTGGACAGTCGGCCCAGGCTGGAGGGCAGGGAAGCACTGAGGCGTTTGGTGAACCGGGGCATACGATGTACTTACGTGCTCATTTCTGCCGTCTCCTATGTTCTGCCTGAGGTATCCAAGGTGTTTCTTGGGGCTCATGCACTTCTGGCCAACGGATACGTGATGTCCCGTGTGGGAACGTCTCAAATCGCCCTGGTGGCAAAGGCCTATAATGTGCCTGTGCTGGTCTGCTGTGAGACCTACAAGTTCTGTGAACGAGTGCAGACGGATTCCTTCGTATCTAATGAACTTGATGACCCTGACGACCTGATTGTGACTCGGAAGGGAAAGACACATCTGGCGGACTGGCAGAGCGAGACGTCCTTGGGCCTGCTGAACTTGGTGTATGATGTAACACCTCCAGACTTTGTTGACCTGGTGATCACAGAGTTAGGCATGATCCCCTGTACTTCTGTGCCTGTAGTACTACGAGTTAAGAACGTGGATCAGTAAAGAAAGCGGCTTCTGCTTTGCATTTGTGCATTCACAAACCTTAACACAGTGGGCTTTTGGCATAAAATAAACCTGTATCTAAAATGGCACATGCTTTTAAT

Function


symbol description
eif2b4 Predicted to enable translation initiation factor activity. Predicted to act upstream of or within translational initiation. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B4 (eukaryotic translation initiation factor 2B subunit delta).

NR:

description
PREDICTED: translation initiation factor eIF-2B subunit delta-like

GO:

id name namespace
GO:0019509 L-methionine salvage from methylthioadenosine biological_process
GO:0043087 regulation of GTPase activity biological_process
GO:0045947 negative regulation of translational initiation biological_process
GO:0005851 eukaryotic translation initiation factor 2B complex cellular_component
GO:0046523 S-methyl-5-thioribose-1-phosphate isomerase activity molecular_function
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function
GO:0003743 translation initiation factor activity molecular_function

KEGG:

id description
K03680 EIF2B4; translation initiation factor eIF-2B subunit delta

RNA


RNA id representative length rna type GC content exon number start site end site
XM_022663821.1 False 1795 mRNA 0.49 13 59562829 59573609
XM_022663830.1 True 1839 mRNA 0.49 14 59562829 59573611

Neighbor


gene id symbol gene type direction distance location
LOC103027424 si:ch211-278j3.3,LOC108435005,LOC108257871,LOC107723221,LOC107589055,LOC105897761 coding downstream 76086 59445511 ~ 59486743 (-)
LOC103026850 LOC108435006,LOC107589054,LOC107723250,LOC107746162,LOC107697321,LOC104922452 coding downstream 128516 59358827 ~ 59434313 (-)
ccm2 ccm2 coding downstream 566067 58976662 ~ 58996762 (-)
LOC111189957 enpp5,LOC107746078,LOC107561943,LOC107701510 coding downstream 609944 58947653 ~ 58952885 (-)
LOC103037326 enpp5,LOC107561943,LOC107701510,LOC107746078 coding downstream 620632 58934892 ~ 58942197 (-)
LOC103030505 LOC103030505,LOC108434978 coding upstream 25809 59599420 ~ 59608991 (-)
LOC107197813 NA coding upstream 126423 59700034 ~ 59704083 (-)
LOC103031863 LOC108434997,LOC108258133,LOC105920313 coding upstream 218965 59792576 ~ 59830891 (-)
LOC103032183 kcnh5a,LOC108434995,LOC107701494,LOC107563685,LOC107743971,LOC107707078,LOC107697309,LOC108257569 coding upstream 308529 59882140 ~ 60059600 (-)
LOC103032801 ppp2r5ea,LOC103032801,LOC108434994,LOC108257929,LOC107697307,LOC107701493,LOC107707079,LOC107743972,LOC107563687 coding upstream 523877 60097488 ~ 60123478 (-)
G29492 NA non-coding downstream 3165 59554331 ~ 59559664 (-)
G29480 NA non-coding downstream 119827 59442779 ~ 59443002 (-)
G29417 NA non-coding downstream 237117 59324993 ~ 59325712 (-)
G29393 NA non-coding downstream 318994 59236497 ~ 59243835 (-)
G29370 NA non-coding downstream 429157 59133411 ~ 59133672 (-)
G29494 NA non-coding upstream 717 59574328 ~ 59574536 (-)
LOC111190079 NA non-coding upstream 2627 59576238 ~ 59578395 (-)
G29509 NA non-coding upstream 33564 59607175 ~ 59607846 (-)
G29559 NA non-coding upstream 278444 59852055 ~ 59852468 (-)
G29563 NA non-coding upstream 284455 59858066 ~ 59858339 (-)
snx17 snx17 other downstream 9919 59506926 ~ 59552910 (-)
G29478 NA other downstream 124531 59437600 ~ 59438298 (-)
LOC103023855 xkr6b,xkr6,LOC103023855,LOC108435015,LOC107746102,LOC107701509,LOC108258067,LOC107589046,LOC107723320,LOC107684793 other downstream 476943 58998541 ~ 59085886 (-)
G29317 eif5,LOC103022293,LOC107561927,LOC107746071,LOC108435020,LOC107589079,LOC107701513,LOC107582488 other downstream 628040 58932963 ~ 58934789 (-)
LOC111189852 LOC108411318,LOC108257913,LOC107721335,LOC102302990,LOC102081001 other downstream 1388125 58159207 ~ 58174704 (-)
LOC103034188 LOC108434976 other upstream 575786 60149397 ~ 60162066 (-)
LOC103035785 ppm1a,LOC108434987,LOC108258036 other upstream 777661 60351272 ~ 60364744 (-)
LOC111191938 NA other upstream 795435 60369046 ~ 60369614 (-)
LOC103029720 jag2,jag2b,LOC107718403,LOC107755239 other upstream 1719265 61292876 ~ 61364878 (-)
LOC103043586 mark3b,LOC108412004,LOC107697167,LOC108258043 other upstream 2258230 61831841 ~ 61890729 (-)

Expression



Co-expression Network