LOC103027723 (ppara)



Basic Information


Item Value
gene id LOC103027723
gene name ppara
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035903.1
NCBI id CM008306.1
chromosome length 40813162
location 4048242 ~ 4074563 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007232266.3
ATTATCGGGGGGTTTTGAAAGCAGTGTCGGGGGCGGGGTAGGGTACAGGAGGGTTTAGGATGGGGTTAAACCCGGTCTCTGGAGGTGCATCGCTAGAGCCTGGACTCGGCCAACTTCACTCAGTCTGATGTGtgattcagtgattgccgtggtcCGGCGCCATGGTAGACGTACCCAGTCTGTTCAGTCCCTTGTCTCCAGTGGGGGAGTCAGTGTTGGACAGCCCGCTGTGTGGGGAGCTGATCATGAACATGGAGGAGCTCGAGGACATCACCTGCTCCCTCAGCGAGGACCCGTTCAATCTGCTCTACATGCCTGACTGGCAgagctccagcaccagctctgaaagctctactGTTCAAGaagTCCCGAGTCCAGCCTCTAGCCCTTCCTCTACAGTGTACGGAGTGGTCACAGGCGCGGATGAAGTCATCTCCAGCCCGCTGAATCTTGAGTGTCGCGTGTGTGCCGATCGTGCCTCTGGCTTTCACTATGGAGTGCATGCCTGTGAGGGATGCAAGGGTTTCTTCAGGAGAACCATACGCCTCAAGCTGGAGTATGACAAGTGTGAGCGCAACtgtaaaatacagaagaaaaaccGGAACAAGTGTCAGTACTGCCGCTTCCACAAGTGCCTTGCTGTGGGCATGTCCCATAATGctATCCGTTTCGGTCGGATGCCCCGCTCAGAGAAGATGAAGCTGAGAGCGAAGCTGCAGACCGGAGAGATAGAGGATGGAGAGACGCAGTTGGCTGATCTGAAGAGTCTGGCCAGGCAGATCCACGAAGCCTACCTCAAAAACTTCCAAATGAGCAAGGCCAAAGCACGAGTCTTCCTCGCTGGGAAGACCAGCACATCACCTTTTGTCATCCATGACCTGGAAACCCTGCAGCAGGCGCAGTCCATCCTAGCTGCCCAGATGCTGGTTGATGAGAAGGAAGAGTTGGTGAGTGGTGTGCAGGAACGAGAGACAGAGTCCCACCTCTTTCGCTGCTGCCAGTACACCTCAGTGGAAACGGTCACCCAGCTGACTGAATTCGCCAAAGCTGTGCCGGGCTTCGCGAGTCTGGACATAAACGACCAGGTGACTCTGCTAAAGTATGGTGTGCATGAGGCCTTTTTCACGCTGCTGTCCTCCTACATGAACAAGGATGGGCTGCTGGTGGCCAGCGGTGGCGGCTTCATCACCCGCGAATTCTTAAAGAGCCTCCGACGACCCTTCAGCGACATGCTGGAGCCCAAGTTCCAGTTCGCCATACGCTTCAACGCTCTGGAGCTGGATGACAGTGATCTGGCGCTATTTGTGGCCACAATCATCTGCTGTGGAGACCGACCAGGACTGGCAAACGTGTCAGACATTGAATGCATTCAAGAAAGTATCGTCAATGCTCTACGACTCCATCTGCAGGCCAACCACCCTGACAACACCATGCTCTTCCCCAAACTCCTGCAGAAACTGGCTGACCTTCGGGAGCTGGTAACAGAGCACGCTCAGCTGGTGGAGGACATTAAGAACACACAGGACAGTTTTCTCCACCCACTACTGCAGGAAATCTACAAGGATATGTACTGAGGACTGAACCTTTGGGTGGTAAGACTGGATTTCAGGCTGCCTTTGATAAACTCTGGTGGTCTGGTGGAAGTTGGATTCGCGCTGATCACAGTTCCGAAACAGTAAACTATCATGGATTTTGCAAGAGTTTAAGATTTTAATGGCTGTCCATTAATCCGCCTAACCTATAGACTGCAGTACAAGCCTTCATTCAGAGATGTACAACACACACGAAAACACTGCTGCAAGCAGGTCCTTCAATCAACAGTTTCTCTGACATCACTGCCAATCAAACTTCTTGCCATGAATTTTTGAAGTGAAGTTGTTTTATACCTTctgaaagcagtgtgtaagctATTTTCAAAACGCATCTGTAGTAATAATGTGAATAGAATAAATGCTGGATTAACATGTATAGTAGTTTTAGTTGTAAGAATGTGAATATAAACAGTTTATGCACTCCACCTTTATTAATCAAaagatgttatttatttttgaaaatatgaaACCAGTGCCATTAGAAGAAGCTAATTAATATATGACTgaatgttaatgtgtgtgtgtgtgtgtgt
>XM_007232267.3
CAGGAGAGTAGTGTGTGGGGTTTGGACTTTGGCCCCCGCCGAGGCCAGTGTATttattggctgctgctgctagAACAGACTTGTGAAGAGTGATCTGTCTGATGTGtgattcagtgattgccgtggtcCGGCGCCATGGTAGACGTACCCAGTCTGTTCAGTCCCTTGTCTCCAGTGGGGGAGTCAGTGTTGGACAGCCCGCTGTGTGGGGAGCTGATCATGAACATGGAGGAGCTCGAGGACATCACCTGCTCCCTCAGCGAGGACCCGTTCAATCTGCTCTACATGCCTGACTGGCAgagctccagcaccagctctgaaagctctactGTTCAAGaagTCCCGAGTCCAGCCTCTAGCCCTTCCTCTACAGTGTACGGAGTGGTCACAGGCGCGGATGAAGTCATCTCCAGCCCGCTGAATCTTGAGTGTCGCGTGTGTGCCGATCGTGCCTCTGGCTTTCACTATGGAGTGCATGCCTGTGAGGGATGCAAGGGTTTCTTCAGGAGAACCATACGCCTCAAGCTGGAGTATGACAAGTGTGAGCGCAACtgtaaaatacagaagaaaaaccGGAACAAGTGTCAGTACTGCCGCTTCCACAAGTGCCTTGCTGTGGGCATGTCCCATAATGctATCCGTTTCGGTCGGATGCCCCGCTCAGAGAAGATGAAGCTGAGAGCGAAGCTGCAGACCGGAGAGATAGAGGATGGAGAGACGCAGTTGGCTGATCTGAAGAGTCTGGCCAGGCAGATCCACGAAGCCTACCTCAAAAACTTCCAAATGAGCAAGGCCAAAGCACGAGTCTTCCTCGCTGGGAAGACCAGCACATCACCTTTTGTCATCCATGACCTGGAAACCCTGCAGCAGGCGCAGTCCATCCTAGCTGCCCAGATGCTGGTTGATGAGAAGGAAGAGTTGGTGAGTGGTGTGCAGGAACGAGAGACAGAGTCCCACCTCTTTCGCTGCTGCCAGTACACCTCAGTGGAAACGGTCACCCAGCTGACTGAATTCGCCAAAGCTGTGCCGGGCTTCGCGAGTCTGGACATAAACGACCAGGTGACTCTGCTAAAGTATGGTGTGCATGAGGCCTTTTTCACGCTGCTGTCCTCCTACATGAACAAGGATGGGCTGCTGGTGGCCAGCGGTGGCGGCTTCATCACCCGCGAATTCTTAAAGAGCCTCCGACGACCCTTCAGCGACATGCTGGAGCCCAAGTTCCAGTTCGCCATACGCTTCAACGCTCTGGAGCTGGATGACAGTGATCTGGCGCTATTTGTGGCCACAATCATCTGCTGTGGAGACCGACCAGGACTGGCAAACGTGTCAGACATTGAATGCATTCAAGAAAGTATCGTCAATGCTCTACGACTCCATCTGCAGGCCAACCACCCTGACAACACCATGCTCTTCCCCAAACTCCTGCAGAAACTGGCTGACCTTCGGGAGCTGGTAACAGAGCACGCTCAGCTGGTGGAGGACATTAAGAACACACAGGACAGTTTTCTCCACCCACTACTGCAGGAAATCTACAAGGATATGTACTGAGGACTGAACCTTTGGGTGGTAAGACTGGATTTCAGGCTGCCTTTGATAAACTCTGGTGGTCTGGTGGAAGTTGGATTCGCGCTGATCACAGTTCCGAAACAGTAAACTATCATGGATTTTGCAAGAGTTTAAGATTTTAATGGCTGTCCATTAATCCGCCTAACCTATAGACTGCAGTACAAGCCTTCATTCAGAGATGTACAACACACACGAAAACACTGCTGCAAGCAGGTCCTTCAATCAACAGTTTCTCTGACATCACTGCCAATCAAACTTCTTGCCATGAATTTTTGAAGTGAAGTTGTTTTATACCTTctgaaagcagtgtgtaagctATTTTCAAAACGCATCTGTAGTAATAATGTGAATAGAATAAATGCTGGATTAACATGTATAGTAGTTTTAGTTGTAAGAATGTGAATATAAACAGTTTATGCACTCCACCTTTATTAATCAAaagatgttatttatttttgaaaatatgaaACCAGTGCCATTAGAAGAAGCTAATTAATATATGACTgaatgttaatgtgtgtgtgtgtgtgtgt
>XM_022671245.1
TGGTGTTGAATGGCCGCAGGGGGCATGGCTACCCTGTTCTTGGCAGCAGTGCTGTGTCATGAGGCTGGAGTCACGCTCTGATGTGtgattcagtgattgccgtggtcCGGCGCCATGGTAGACGTACCCAGTCTGTTCAGTCCCTTGTCTCCAGTGGGGGAGTCAGTGTTGGACAGCCCGCTGTGTGGGGAGCTGATCATGAACATGGAGGAGCTCGAGGACATCACCTGCTCCCTCAGCGAGGACCCGTTCAATCTGCTCTACATGCCTGACTGGCAgagctccagcaccagctctgaaagctctactGTTCAAGaagTCCCGAGTCCAGCCTCTAGCCCTTCCTCTACAGTGTACGGAGTGGTCACAGGCGCGGATGAAGTCATCTCCAGCCCGCTGAATCTTGAGTGTCGCGTGTGTGCCGATCGTGCCTCTGGCTTTCACTATGGAGTGCATGCCTGTGAGGGATGCAAGGGTTTCTTCAGGAGAACCATACGCCTCAAGCTGGAGTATGACAAGTGTGAGCGCAACtgtaaaatacagaagaaaaaccGGAACAAGTGTCAGTACTGCCGCTTCCACAAGTGCCTTGCTGTGGGCATGTCCCATAATGctATCCGTTTCGGTCGGATGCCCCGCTCAGAGAAGATGAAGCTGAGAGCGAAGCTGCAGACCGGAGAGATAGAGGATGGAGAGACGCAGTTGGCTGATCTGAAGAGTCTGGCCAGGCAGATCCACGAAGCCTACCTCAAAAACTTCCAAATGAGCAAGGCCAAAGCACGAGTCTTCCTCGCTGGGAAGACCAGCACATCACCTTTTGTCATCCATGACCTGGAAACCCTGCAGCAGGCGCAGTCCATCCTAGCTGCCCAGATGCTGGTTGATGAGAAGGAAGAGTTGGTGAGTGGTGTGCAGGAACGAGAGACAGAGTCCCACCTCTTTCGCTGCTGCCAGTACACCTCAGTGGAAACGGTCACCCAGCTGACTGAATTCGCCAAAGCTGTGCCGGGCTTCGCGAGTCTGGACATAAACGACCAGGTGACTCTGCTAAAGTATGGTGTGCATGAGGCCTTTTTCACGCTGCTGTCCTCCTACATGAACAAGGATGGGCTGCTGGTGGCCAGCGGTGGCGGCTTCATCACCCGCGAATTCTTAAAGAGCCTCCGACGACCCTTCAGCGACATGCTGGAGCCCAAGTTCCAGTTCGCCATACGCTTCAACGCTCTGGAGCTGGATGACAGTGATCTGGCGCTATTTGTGGCCACAATCATCTGCTGTGGAGACCGACCAGGACTGGCAAACGTGTCAGACATTGAATGCATTCAAGAAAGTATCGTCAATGCTCTACGACTCCATCTGCAGGCCAACCACCCTGACAACACCATGCTCTTCCCCAAACTCCTGCAGAAACTGGCTGACCTTCGGGAGCTGGTAACAGAGCACGCTCAGCTGGTGGAGGACATTAAGAACACACAGGACAGTTTTCTCCACCCACTACTGCAGGAAATCTACAAGGATATGTACTGAGGACTGAACCTTTGGGTGGTAAGACTGGATTTCAGGCTGCCTTTGATAAACTCTGGTGGTCTGGTGGAAGTTGGATTCGCGCTGATCACAGTTCCGAAACAGTAAACTATCATGGATTTTGCAAGAGTTTAAGATTTTAATGGCTGTCCATTAATCCGCCTAACCTATAGACTGCAGTACAAGCCTTCATTCAGAGATGTACAACACACACGAAAACACTGCTGCAAGCAGGTCCTTCAATCAACAGTTTCTCTGACATCACTGCCAATCAAACTTCTTGCCATGAATTTTTGAAGTGAAGTTGTTTTATACCTTctgaaagcagtgtgtaagctATTTTCAAAACGCATCTGTAGTAATAATGTGAATAGAATAAATGCTGGATTAACATGTATAGTAGTTTTAGTTGTAAGAATGTGAATATAAACAGTTTATGCACTCCACCTTTATTAATCAAaagatgttatttatttttgaaaatatgaaACCAGTGCCATTAGAAGAAGCTAATTAATATATGACTgaatgttaatgtgtgtgtgtgtgtgtgt

Function


symbol description
ppara Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; steroid hormone receptor activity; and ubiquitin conjugating enzyme binding activity. Involved in several processes, including negative regulation of lipid storage; regulation of lipid metabolic process; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within negative regulation of protein kinase B signaling; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of viral genome replication. Located in nucleoplasm. Implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Biomarker of cystic fibrosis and fatty liver disease.

NR:

description
PREDICTED: peroxisome proliferator-activated receptor alpha

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0043401 steroid hormone mediated signaling pathway biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0004879 nuclear receptor activity molecular_function
GO:0003707 steroid hormone receptor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007232266.3 True 2125 mRNA 0.50 7 4048242 4074563
XM_007232267.3 False 2099 mRNA 0.50 7 4052342 4074563
XM_022671245.1 False 2078 mRNA 0.50 7 4054051 4074563

Neighbor


gene id symbol gene type direction distance location
atxn10 atxn10 coding upstream 79286 3956662 ~ 3968956 (+)
LOC103029111 NA coding upstream 98508 3937491 ~ 3949734 (+)
LOC103031106 LOC108438797 coding upstream 194515 3847043 ~ 3853727 (+)
cfap54 NA coding upstream 353318 3656162 ~ 3694924 (+)
mcat mcat,LOC107553884,LOC107732994 coding upstream 396591 3645317 ~ 3651651 (+)
mcm10 NA coding downstream 9120 4083683 ~ 4099389 (+)
LOC103041372 LOC103041372,LOC108425387,LOC107710120,LOC107580024,LOC100535105,LOC107658877,LOC108279439,LOC107656361,LOC107726057 coding downstream 600796 4675359 ~ 4701435 (+)
ifrd1 ifrd1,LOC108425389,LOC107726045,LOC107580056 coding downstream 1176570 5251133 ~ 5261551 (+)
LOC107197570 LOC108442310 coding downstream 1347205 5421768 ~ 5423304 (+)
LOC111192904 NA coding downstream 1938283 6012846 ~ 6015114 (+)
LOC103028258 NA non-coding upstream 3934 4011384 ~ 4044308 (+)
LOC111192865 NA non-coding upstream 333994 3713557 ~ 3714248 (+)
LOC111192864 NA non-coding upstream 334819 3712242 ~ 3713423 (+)
G61657 rint1 non-coding upstream 350461 3695234 ~ 3697781 (+)
G61607 NA non-coding upstream 650470 3394516 ~ 3397772 (+)
G61815 NA non-coding downstream 48119 4122682 ~ 4122963 (+)
G61790 NA non-coding downstream 55754 4130317 ~ 4131090 (+)
G61786 NA non-coding downstream 57200 4131763 ~ 4136771 (+)
G61852 NA non-coding downstream 68498 4143061 ~ 4143691 (+)
LOC111192934 LOC108425385,LOC108279691,LOC107710083 non-coding downstream 245289 4319852 ~ 4325034 (+)
G61575 NA other upstream 744244 3296546 ~ 3303998 (+)
LOC103036328 tmem178b,LOC107725619,LOC107694293,LOC107590312,LOC107655551 other upstream 2112743 1921395 ~ 1935499 (+)
LOC103031096 pclo,pcloa,LOC107655554,LOC107577557 other upstream 2239312 1714817 ~ 1808930 (+)
LOC103024246 tspan11,LOC108279944,LOC107593980,LOC106576552,LOC107720401,LOC107560736,LOC107694254 other upstream 2566824 1445635 ~ 1481418 (+)
G61013 LOC108444125,LOC108444119,LOC108412201,LOC108262118 other upstream 3004926 853526 ~ 1043316 (+)
LOC111192936 NA other downstream 1665992 5740555 ~ 5765785 (+)
plxnb2 NA other downstream 1707528 5782091 ~ 5967735 (+)
c7h12orf75 NA other downstream 1907673 5982236 ~ 5993994 (+)
G62455 gpr85,LOC106576049,LOC107580073 other downstream 2776667 6851230 ~ 6855762 (+)
rab19 rab19,LOC108425368,LOC106523538 other downstream 4327277 8401840 ~ 8415039 (+)

Expression



Co-expression Network