hes1 (hes1,her6,LOC107711114,LOC107680502,LOC107722674,LOC107685314,LOC107582845)


Basic Information

Item Value
gene id hes1
gene name hes1,her6,LOC107711114,LOC107680502,LOC107722674,LOC107685314,LOC107582845
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035909.1
NCBI id CM008312.1
chromosome length 44161018
location 39209814 ~ 39211823 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007249064.3
AATAAGCGCGCGCGGTGCGGGCAGGCGGTCAGTCACTCGCTCAGTCGCTCGCGCGGTCGCTCGCTCAGTGCTGCTGGCAAACGGCGAGAGCAGGAGCCGTGACATCGTCACCACGAGCTGTTTAACTCAGGACGCTGCGACGggacttttctctttttttaagacCCACTGTTACGCGGTCTGGACTTGTAAATAAATACGAAAAGCACGCGCAGCGCTGTCTGCCACTGAAGACTGAACACTCGCGAAggatttctcttctttttccacGGTTTTCGGGGATATTGCAGCAAAAGATGCCGGCTGACATGATGGAAAAAAACTCTTCATCCCCGGTGGCCGCGACCCCGGCGAGCATGAACACCACGCCGGATAAGCCCAAGACAGCCTCCGAGCACAGAAAGTCGTCCAAACCCATTATGGAGAAAAGGAGACGAGCCAGAATCAACGAAAGCTTGGGACAACTCAAAACGCTAATCCTGGATGCTCTGAAAAAAGATAGCTCCAGACACTCGAAACTGGAGAAGGCGGATATCCTGGAGATGACTGTGAAGCACCTCCGAAACATGCAGCGAGCACAAATGACTGCTGCTCTGAACACAGATCCCACCGTTCTTGGAAAGTACAGGGCTGGATTCAGCGAGTGCATGAACGAGGTCACCCGATTCCTGTCCACCTGCGAAGGGGTTAATGCCGAGGTCAGGACGCGGCTGCTGGGTCACTTAGCCAACTGCATGACGCAGATCAACGCCATGAACTACCCCACGCAGCACCAGATAGCTGCTGGCCACCCGCACCCGACCTTCGCCCAGCCCATGGTTCAGATCCCCGGTGGAACACCACAGGCCAACGTGCTGCCTCTCAGTGGAGTACCCTGCAAAAGTGGGTCCTCATCCAACTTGTCACCCGAAGCCACCAAGGTGTACGGAGGATTCCAGCTCGTACCAGCAACAGATGGACAGTTTGCCTTTTTGATTCCCAACGCCGCGTTTGCACCCAGTGGTCCTGTAATCCCAGTATATGCCAACAACTCCAGCACACCCGTTCCAGCGGCAGTATCTCCAGGCGCACCTTCAGTCACCTCAGACTCTGTGTGGCGGCCTTGGTAGACCTTAAAAGACTCCTAAAAAGAGACTTCTAAAAAAGACTCTTAACTGTTGACACTTGTTCTGTTCgtttaaacgtttcatttcttATTTTGGTCTTTTTGTATGGAAATGTGTTTAAGAAGAGATTTATGCACTATATTTGTACAGCGCAAAAGGGAGAAAAGTTCATATTGAAATAAGATTTGTATTGTTGATGTTTGttcattgcatttttttatatttgcggTATCTTTTCTAACGTTGATGCCAAAGATATGTTGAATGCTTTTGCAGAATTCTTCGTTTTGGAAGATtaataaatttgtaaaaaaaaaaaaaa

Function

symbol description
her6 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including Notch signaling pathway; nervous system development; and somite specification. Predicted to be active in nucleus. Is expressed in several structures, including anterior neural keel; mesoderm; nervous system; neuronal stem cell; and pectoral fin. Orthologous to human HES1 (hes family bHLH transcription factor 1).
hes1 Enables histone deacetylase binding activity and sequence-specific double-stranded DNA binding activity. Involved in several processes, including negative regulation of cell differentiation; negative regulation of transcription by RNA polymerase II; and neuronal stem cell population maintenance. Located in nucleoplasm.

NR:

description
transcription factor HES-1

GO:

id name namespace
GO:0021794 thalamus development biological_process
GO:0007219 Notch signaling pathway biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0001757 somite specification biological_process
GO:0045664 regulation of neuron differentiation biological_process
GO:0005634 nucleus cellular_component
GO:0003677 DNA binding molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG:

id description
K06054 HES1; hairy and enhancer of split 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007249064.3 True 1428 mRNA 0.49 4 39209814 39211823

Neighbor

gene id symbol gene type direction distance location
opa1 opa1,LOC107711112,LOC107582739,LOC107673572,LOC107585173 coding upstream 128703 39032127 ~ 39081111 (+)
cth cth,LOC102785392 coding upstream 775957 38417049 ~ 38433857 (+)
nit2 nit2,LOC107582734,LOC107585165,LOC107673472,LOC107685305 coding upstream 802517 38403349 ~ 38407297 (+)
LOC103035541 plcxd1,LOC103035541,LOC105895009,LOC107673474,LOC107711026,LOC107585164,LOC108441321,LOC107753403,LOC108271842 coding upstream 821768 38381185 ~ 38388046 (+)
jade3 jade3,LOC107711098,LOC107685301,LOC107753402,LOC107582729 coding upstream 833387 38357858 ~ 38376427 (+)
LOC103022251 brinp3a.2,LOC108440126,LOC107711116,LOC107732449,LOC107685312,LOC107667973,LOC107585215 coding downstream 305677 39517500 ~ 39594023 (+)
LOC103028032 brinp3a.1,LOC108441513,LOC107585174,LOC107711117,LOC107732447,LOC107685317 coding downstream 742650 39954473 ~ 40009536 (+)
LOC103027818 rgs8,LOC108441527,LOC108271678,LOC107711118,LOC107551030,LOC107732448,LOC107564081 coding downstream 1012228 40224051 ~ 40259219 (+)
LOC103040699 LOC103040699,LOC108440142,LOC108271632 coding downstream 1061563 40273386 ~ 40276489 (+)
LOC103040381 rgs5a,LOC108441543,LOC107732440,LOC107564083,LOC107685321,LOC107684230 coding downstream 1106935 40318758 ~ 40339674 (+)
G116960 NA non-coding upstream 58596 39150829 ~ 39151218 (+)
G116957 NA non-coding upstream 124914 39084679 ~ 39084900 (+)
G116886 NA non-coding upstream 226255 38980409 ~ 38983559 (+)
G116869 NA non-coding upstream 255003 38953227 ~ 38954811 (+)
G116852 NA non-coding upstream 581650 38626794 ~ 38628164 (+)
G116975 NA non-coding downstream 60074 39271897 ~ 39282073 (+)
G116978 NA non-coding downstream 72399 39284222 ~ 39285631 (+)
G116979 NA non-coding downstream 73884 39285707 ~ 39287709 (+)
G116985 NA non-coding downstream 113720 39325543 ~ 39325769 (+)
G116994 NA non-coding downstream 141612 39353435 ~ 39353788 (+)
LOC103036266 LOC108441345 other upstream 815284 38390277 ~ 38394530 (+)
gabra5 gabra5,LOC107711088,LOC107673539,LOC107585151,LOC107685289 other upstream 1597492 37524851 ~ 37612322 (+)
LOC103045245 vdrb,LOC108272216,LOC107585146,LOC107673565,LOC107711077,LOC108441087 other upstream 2088487 37100014 ~ 37121327 (+)
LOC103044253 LOC108440873 other upstream 2495930 36657392 ~ 36713884 (+)
LOC103024058 LOC103024058,LOC108440764,LOC107748389,LOC107711047,LOC107673509,LOC107585116,LOC106583201 other upstream 2850037 36342985 ~ 36359777 (+)
G116997 NA other downstream 147048 39358871 ~ 39359388 (+)
LOC103033994 LOC103033994,LOC108441647 other downstream 1587648 40799471 ~ 40808545 (+)
fam183a NA other downstream 1947364 41159187 ~ 41166159 (+)
pomgnt1 pomgnt1,LOC102776429 other downstream 2141678 41353501 ~ 41367729 (+)
G117642 NA other downstream 3139984 42351807 ~ 42355784 (+)

Expression


Co-expression Network