tpmt (tpmt)


Basic Information

Item Value
gene id tpmt
gene name tpmt
gene type misc
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035919.1
NCBI id CM008322.1
chromosome length 38085671
location 32053715 ~ 32067640 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>TU273267
ggctgtGCAGTCGGTGTTGTTTTGAGCTGGAGACTGGTGCACTCAGGTATTCATCTGAGACTTGCTGGTGAGATGGCAGCCCAGGCAGACAGAGTGATGGCGCTGGGAGAGTGGGAAGGCAGGTGGAATGAAGGGAGGACTGGATTCCATCAGGCTCACATTCACAGG
>XM_007247888.2
CAATGGCTGAGACGACTCCGCCCACTCTGTCCTCTGACCTGCTCTtcctgtttctgaggctgtGCAGTCGGTGTTGTTTTGAGCTGGAGACTGGTGCACTCAGGTATTCATCTGAGACTTGCTGGTGAGATGGCAGCCCAGGCAGACAGAGTGATGGCGCTGGGAGAGTGGGAAGGCAGGTGGAATGAAGGGAGGACTGGATTCCATCAGGCTCACATTCACAGATTGCTGGAGGGGAACATTGACAAAATTTTGTGTGGGAGACAGAAAGTTCGGTTCTTCTTCCCTCTCTGTGGTAAAGCTGTAGACATGAAATGGCTGGCTGACATGGGTCATGAAATTGTTGGAGTGGAGATTTCAGAGACAGGAATAAAGCAGTTCTTTGAAGAGCAGGGTCTGGAGTACAAAGAAGAGCCAGTGGCAGCTATACCTGAAGCCAAAGTGTATAAGAGTTCCGACGGGAAGATCTCCATCTATCAGTGTGATTTATACAACTTCTCCAGTGCAATAGAGGGGCAGTTTGGTGGGATTTGGGATAGAGGATCTCTGGTGGCCATAAACCCATGTGACAGGAGAAAGTATGCCACTCTCATCACATCCTTAATGGATAAAGACTGCAGATACCTCCTGGATATATTTGAATACAACCCCGAACTCTATAAAGGTCCACCATTTTTTGTGCCTGAAGATGAAGTAAAACAATTATATGGAGGCGCTTGTGACATTGAACTCTTGCAGTCGGTGGATAGCTTTTCAGAGAGACATAAAGCATGGGGAATAGATTCACTGCTAGAGAAAGTGTTCCTGCTGACTCCGAAAGCCAACTGAGCGTAAAGGCTTTTATAGAACAGATGTAGCCACTGTTCTGCACACTTACACATAGCAGAATAGCAGAAATGATCAGAGAATCGTATCCATTTCATCTGCATGTAagtggatgttttttttaaagtgaacaAGTCCcaataaaaagctattttaatattta

Function

symbol description
tpmt Enables S-adenosyl-L-methionine binding activity and thiopurine S-methyltransferase activity. Involved in xenobiotic metabolic process. Predicted to be located in cytosol. Implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and thiopurine S-methyltransferase deficiency. Biomarker of inflammatory bowel disease.

NR:

description
PREDICTED: thiopurine S-methyltransferase

GO:

id name namespace
GO:0032259 methylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0008119 thiopurine S-methyltransferase activity molecular_function

KEGG:

id description
K00569 TPMT, tpmT; thiopurine S-methyltransferase

RNA

RNA id representative length rna type GC content exon number start site end site
TU273267 False 168 lncRNA 0.56 2 32053772 32056608
XM_007247888.2 True 988 mRNA 0.45 10 32053715 32067640

Neighbor

gene id symbol gene type direction distance location
trnaq-cug_20 NA coding upstream 621740 31431904 ~ 31431975 (+)
trnaq-cug_19 NA coding upstream 622073 31431571 ~ 31431642 (+)
trnaq-cug_18 NA coding upstream 622403 31431241 ~ 31431312 (+)
trnar-acg_20 NA coding upstream 622692 31430951 ~ 31431023 (+)
trnaq-uug_6 NA coding upstream 623097 31430547 ~ 31430618 (+)
LOC103047171 ext1,ext1c,LOC107592945,LOC107706241,LOC107654729,LOC107688378,LOC107754264 coding downstream 4005 32071645 ~ 32180536 (+)
ncdn NA coding downstream 119517 32187157 ~ 32193783 (+)
tfap2e tfap2e coding downstream 128575 32196215 ~ 32211930 (+)
LOC103044735 LOC108430542,LOC107591984,LOC108257069,LOC107654683,LOC107592950,LOC107754258 coding downstream 224539 32292179 ~ 32295555 (+)
cdca8 cdca8 coding downstream 232734 32300374 ~ 32304369 (+)
G201206 NA non-coding upstream 113775 31939501 ~ 31939940 (+)
G201167 NA non-coding upstream 421962 31548349 ~ 31631753 (+)
G201163 NA non-coding upstream 601959 31441445 ~ 31451756 (+)
G201135 NA non-coding upstream 790755 31259945 ~ 31262960 (+)
G201019 nup153,LOC107706220 non-coding upstream 1023826 31018604 ~ 31029889 (+)
G201281 LOC108430540,LOC102218321,LOC103154989,LOC108257141,LOC103371078,LOC103461361 non-coding downstream 114055 32181695 ~ 32186335 (+)
G201289 psmb2,LOC107591978,LOC107592948,LOC107688376 non-coding downstream 149494 32217134 ~ 32228952 (+)
G201287 NA non-coding downstream 186849 32254489 ~ 32260203 (+)
G201308 LOC108430568,LOC107567795 non-coding downstream 247595 32315235 ~ 32323517 (+)
G201314 LOC108430568 non-coding downstream 263238 32330878 ~ 32360359 (+)
G201207 NA other upstream 66658 31942202 ~ 31987057 (+)
rbm24 rbm24,rbm24a,LOC107754275,LOC107592929 other upstream 969082 31009926 ~ 31084633 (+)
G201018 NA other upstream 1038670 31012711 ~ 31015045 (+)
lypla2 lypla2,lypa2 other upstream 2485640 29528063 ~ 29568075 (+)
eloa tceb3 other upstream 2500831 29542748 ~ 29552884 (+)
LOC103043810 ago4,LOC106511154,LOC103043810 other downstream 201658 32269298 ~ 32287803 (+)
G201445 flii,LOC107581766,LOC107737969,LOC107703428,LOC107674686 other downstream 855888 32923528 ~ 32927919 (+)
bud31 bud31,LOC107737741,LOC107720055 other downstream 906680 32974320 ~ 32977910 (+)
G201466 LOC102799139,LOC107581721 other downstream 1192533 33260173 ~ 33274907 (+)
psmg3 psmg3 other downstream 1743792 33811432 ~ 33814986 (+)

Expression


Co-expression Network