LOC103027820 (npr1,npr1a,LOC108435512,LOC107694365,LOC107677481,LOC107754786,LOC106588322)


Basic Information

Item Value
gene id LOC103027820
gene name npr1,npr1a,LOC108435512,LOC107694365,LOC107677481,LOC107754786,LOC106588322
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035919.1
NCBI id CM008322.1
chromosome length 38085671
location 15465492 ~ 15582858 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007228521.3
TAGTGGAGTTGTGCGCGCGCTGCCCACAtgaatcctcctcctcctcctccactgtAAGTGAGGTTCAGTCAGTGGAGCGCGCGGCTCCGCGGCTCTCTGGATTTATTAACTGCAGACCACTGAAGCGCGCGCCCCCTCTGAGCGGATCCATACTACAGATTACACTTTAACTTCTCTATCGGggagattcagagagagagagagaggagtggaggaggaggacggaCTTCTGTTCCCCCGCTAAACTGAGCTGAGCTGGAGGTTTCCACCGTGTTTACCGGTCACTCTGAGGAAGGAGCTGAGGAGGGAGGAGGACACAGCAGCAGTGAAGAGCGGGGTTAACTAACCTAACTGACCCCGGTCTGCAGCGGCTCCGCTTCCAGGAAGCGCGGAGGAGCTGCGGCATGTTTCCGCTGTAAAGTTTCTGAGGAGGTGTTTTCCATTTCTTCTGAAAGCCGCTGAAGTTTATGAAGAAACACCTGCGAGCAGCAGGAATGGAGACGAGgcgccgccgctgctgctgaaCCTGAGGCCTGGTGATCAGATCGATGCTGAAGATGGAGCCTGGGCTGCTGGGATCAGTGTGGCTCCCGCTTTTGGTTTTGCTCGCTGGTGTGTCATTAGGAGTAATGGAGCTGGAGCCCTTGTCTCAGGAAGAATCTCATCCCGCTGGATCATCTCTCAGGAACATCACTCTGGCTATCATTCtaccaaaacaaaacacagagtACCCGTGGGCCTGGCCCAGAGTGGGCCCTGCTCTCAACTGGGCTCTGGAAAAGGTGAACTCTGACCCCACCCTGCTGCCAGGGTACCACATGCAGCTGGTTTTCAGCAGCAGCGAAAACAAGGAGGGCCTGTGCTCAGACTCAGTGGCTCCTCTAGTGGCTGTGGACTTAAAGTTTGCCCATGACCCGTGGGCCTTCATCGGGCCGGGATGTGACTATGCTTCTTCACCTGTAGCTCGCTTCACCACACACTGGGAGGTTCCAATGGTAACGGCTGGGGCCCCAGCACTGGGCTTTAACATGTACTCGTCCATAACCAATACGGGGCCCACACACAAGAAACTGGGGGAGTTCGTAGTGAGGATGCACCACAACTTTGGCTGGCACAAGTACGCCATGGTCATGTTTCACGACAAAAAGAACGATGACAGGCCGTGCTACTTTGCAGTGGAAGGGCCGTACACAGAGATGACTGCAGACAACATCACTGCCAAAGACATGGTGTTTAATGAAGATGATGAACCACTGTCCTACGCGGATCTTATCAACGGTATCAGCCAGCGAGGACGAGTGGTGTACGTCTGCTGCAAGTGGGACACGTTCCGGAAGCTGATGGTGCAATTTTATAAGCAGAGACTTCCCCAGGAGGAGTATGTCTTCTTCTTTATCGATCTGTTTGGAGAGAGCCTTCGGAGTCGCCCGGCAAAACCATGGGCACGAGGAGACGCAGATGATGAGGCTGCCAAGCAGGCCTTCAAAAGTGTGAAGATCATGACCTACAGAGAGCCTCAGAACCCAGAATATAAGCACTTTGTGTCCAAGATGAAGAGAGATGCCAAGAAGGAGTTTAACTTCAGTATTGAAGACTCACTGATGAACCTGATTGCTGGAGGCTTTCATGACGGAGTGCTGTTATATTCTCATGCCCTGAATGAATCAATGGACCAGTCAGGACTGCGGCCGCCGGGTCATGTGGTCACCAAGAAGATGTGGAACCGCACCTTCCATGGTGTTACAGGCCTGGTGCAGATGGATGAGAACGGCGATCGTGAAATCGATTTTGCTCTCTGGGACATGACGGACACTGAATCAGGAGTTTATGagATTGTGTCTGTGTATAACAGTAGTGCGAAACAGATGGTTCTGGAGCCAGGGATGAAGGTCCATTGGCTGAAAGGCTCTCCTCCTCCTGACATCCCTGTGTGTGGCTTTAAGAATGACAACCCTGCCTGTCTCGCCAAAACGGTCACCATGCACCAGATGATCTCTATAGTGGCGTGCTTCATCTTTATCATCATCGTTACGGTCACCGTCTTCATCTACAGAAAGGTGAAGCTGGAGAACGAGTTGGCCGCTCAGCTGTGGAGGGTTTACTGGGAGGACATTCAGATAAGCAACCTGGACAAAGCGCTGCGCCGAGCCTGCAGCAGATTGACCCTGTCACTGAGAGGCTCCAATTATGGCTCTCTGTTGACCCTGGAGGGAAACGTTCAGATTTACGCCAAAACCTGCTACTACAAGGGAAACATTACAGCCATTAAGTATGTCAACAAGAAACGCATCGAGCTCACCAGGAAAGTGCTGTTTGAACTCAAACATATGCGTGACGTACAGAATGAACACCTGAACAGATTTATTGGAGCCTGCATTGATGCCCCAAACATCTGCATTCTCACTGAGTACTGTCCTCGAGGCAGCCTGCAGGACCTCATGGAGATTGAAAGCATCACACTGGATTGGATGTTTCGCTACTCTCTGATAAATGACATTGTAAAGGGCATGGCATTTCTCCATAACAGTGTGATCGTCTCCCATGGCAACCTAAAGTCCTCCAACTGCTTGGTAGACAGCCGCTTTGTGCTGAAGATCACCGACTATGGCCTGGCCAGCTTTCGCAAAGAGAGCTACTTGGAAGACACGCATGCTTACTATGCACGAAAACTGTGGACAGCTCCAGAGCTGATGCGGGATGAGAACAGACAACCCTGTGGTACACAGAAGGGAGATGTTTACAGCTTCGGCATCATCCTACAGGAACTGGCCTTGCTCAAAGGCGTGTTCTACCTGGACAGCCCCCCATTCAGCCCTAAAGaGATTGTGGAGCATGTAGCTGAAGGCCGATGGCCGTATCTGCGACCGCTGCTGTGCACACAGAGCCACAGTGAGGAGCTGGGTCAGCTGATGCAGCGCTGCTGGTCAGAGGATGTCAACGAGAGGCCAGATTTCAACCAGATCAAAGTGATGCTTCACAAGAACAACAGAGGCTACGGCTCCAACATCCTGGATAACCTGCTGTCTCGCATGGAGCAGTATGCTAATAACCTGGAggagctggtggaggagaggacACAGGCGTACCATGAGGAAAAGCGCAAAGCTGAAGCCCTGCTCTATCAGATCCTGCCTCATTCAGTAGCAGAGCAGTTGAAAAGAGGAGAGACGGTGCAGGCTGAGGCCTTTGACTCTGTCACCATCTACTTCAGTGATATTGTGGGTTTCACCGCAATGTCGGCAGAGAGCACACCTATGCAGGTGGTGACTTTACTGAATGACCTGTACACATGTTTTGATGCCATCATTGACAACTTTGACGTTTACAAGGTGGAGACAATCGGCGATGCCTACATGGTGGTGTCAGGACTACCTGTGAGGAACGGAAAGCTGCATACCGGGGAGATAGCACGCATGTCTTTGGCCCTGCTGGAAGCCGTCTACTCATTCAGGATTCGCCATCGTCCCGACCTACAGCTGCGCCTCCGCATCGGCATCCACACCGGTcctgtgtgtgcaggtgttgtTGGACTGAAGATGCCAAGGTATTGTTTGTTTGGAGACACAGTGAACACAGCTTCACGCATGGAGTCGAATGGAGAAGCCCTGAAGATCCATGTGTCGGAGGCCACACGTGCGGTACTGCAGGAGTTCAACTGCTTCCAGCTGGAGCTGAGAGGAGACATAGAAATGAAAGGCAAGGGGAGGATGAGGACCTATTGGCTTCTGGGAGAAAGCACCTCCAACCATGCCTGAATGGAACAGAGGGAGAACCAAGCAAAATAAGCTTTGTTTCTGAGAGGAGAGCTGCCGATGAGATTTATAAAATCATGTAGCAAAAACGTTCAGAGCTTTGAATGAAGAGagcagagatacagagagaaaaaaacgatTGGAAGAGCCTCAGGATGAGGTCTCAGGACATTGTTTTCTCTCAAAGCTTCAGTTTGTGGCTACACATGAATGTTAACATGACTGGGACAAAATAAGGGAAAAGTGATGTGAAAAATGTCTGACATTTGAAGAAGTTCTGAACATGATGTAAAATTTTCCACAATGCGAACTGTGGCTGTAGTTTGAGGTTGGTGCCATCTAGTggtgaaatactgtatatgtcttCTCATGAATGAACAGTTTATTAGAGTAGCTTCTACATTTTAGCTACATTTTTTGGTAGCCTCACTTTGTTTAAAgacaaatattgtgttttttgcttttccCTGCAAATGAATAGTCTTCTCTATATTGCTACTCAGTATTTCCTGGTGTATTACAGTATGTGAAGCGAAAGACCGTGGATCAATCAACTCCTTCTGctctttaaatacataaaacctCTTGTATGACAATGACTAATAATGCAGCACTGACAGATACAAAGGATGCTGCAGATCCTTGTTGTGATACTCAAAATATGAGGATGGTATACAGGGGGTAGAAATAATGGAAACAGAAGATTTTACAGGTAGAAGTGACTAGATAGTAGTTGAAAAGCAATATGGATGTCTGGGTCTTACTACTGAGAACATGTGCAGTGCTGAGCAGAAGTTCTAAGGCTCATTTATGCTCATTTTAGATTACAAAAAATATCATGCCagttattaacaatgtaaatgtcACGGCCAACATACTACACAACTGTGTGTCCTTTATGCTGGCACTAGAGGGCCGGTCAGAGTCAAACATTCTAAATAGAAAACAACAATGACTTCAATGTAGTTCTGTAGCAGTGTAGTTTGTTTCTGTGCTTCTACCATTTGACAACAATATAGATTGTTTAaatttctcacaaaaaaaactctcttGAAGGTTTTCTTTTCTgcctattttttcttctttattatgtttatatggTAGTAGTACTATGGTAATTTGCTTGATCTGTTGCACACACTGCCCCAAATTTTACTGTTCATATTAGTAACTTCTtagaaaatgcttaaaaaagagcagaaagaaGACTCTGTTCATATCCATGTTTAACACTGAGCATAAATGAGCCTTTAAGTGGCCAAAAcacctgattattttttttttgcctacaTTTGAACATTAGAATACTTGCTATCCATTTAAATGGACTTTTGCCCCGTACTGTTAAACAGTGTCTTACTAGTATAATAAAGGCTTCCAGGATCTTTAGCATTTCAATTTCTAAAGCAATAGGAGGCACCTAACAAACtgtaaaacatattattttccAGATTGAGGCTTAGGAGAACAGGTCAAAGGATAAGTATACTGAAGGTAAGCCTGCTACCATTAGTATACCAACTAGATCCAGAATCAGaaaaagtttacaaagtttATAATAGTTTTTGAAACCAGTTTGTAAGCAAAATAAAGACACATACACATAGCACACCAATTATTCATTCTGAATGACGAGAATCTCTACATGAATAGAAGTCTAAGGTCTGTCTCAGTCAGTGTTGTATAGCAATATTGTACAAATATGTCTCAGTTAATATCCAGCTTTACCTGAATGTCATAAACTTTGTTTTATAAAGGTGAAACAAAGCTTGTTAAAATTACAGTCAAACTGTAATTCTTCTGAATgaattgtactgtatatactatcCTATAAAAAGTACcgtagtttcacattttcagtgCAAGCAGGTGTTGGAaaagtacataaaaaatattactgtgcTGAGCCAAAATTTTCAAAAGTGTGAAAGTCAAGAAATATTGGTATACAAAAGTCACTACACAAAAGTCTGAAAACCTGGTCAATAAACATTTGTAAGCATTTAAGGTTATTGATTTCAATACAAgcgtttaaaataatatttaatgggGCActagcatttattattatttgtcaaACTATTCAGACACTGTTTCAGAACTCCGGTTTCACAGGATTCACAATTTTGTATCATAATCATGCATTACATGAATGtgtcttaagccctatctggacgggattagtttcttagggggatgtctgtgaaaaatattttatactactacttagtgataaaactcagttaactgcaattaaaaaacaggaggaccagtgataTCCGTGGAAACGCGCACCCAAAGTGAAATTAAGGTGCGTGGCAgtagacaaatagctattttattaaacgcgaggtgacgaaactcagagatatgCGTCTGGTCGGGAGTAAAATTACCATGAAGTTCAACGAAAAACAGTAGgaaattcagcctgtaattttctcagaggacgtctgagaaaaacacatacatgatcgttcctgacagaaataaaatcacagaaaaccccacataaaggaaaataattacccccaggaccccctgagaaactaatcccgtcagGATAGGGCTATTGATGTAGAAACAACTAGACAAAGACCACCGAAAAAGCTTGTAGTTTCTCACAAGGGGGggggagcctatcccagcaggcattgGGCAggaggcaggatacaccctggacaggccgccaatctattgcagggcagacagacacacagacacattagaTGTAgcaatagatatatattttttattttgaccaGAGTGCCCCTTTAAGTACAATAGTATAGCACCCATTCCACCCATAATTGCAAGAAAGCTTCTTATGTTCACCCACATTGCCTCATTTCCACTATTTTGTCTACCTCCTGTATATTCATGTTATATTTGATGTATACAAAATGCTGAATGTTAAAGCAAA

Function

symbol description
npr1a Predicted to enable guanylate cyclase activity; natriuretic peptide receptor activity; and peptide hormone binding activity. Acts upstream of or within axon guidance and cardiac muscle cell proliferation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; eye; heart; integument; and kidney. Human ortholog(s) of this gene implicated in Miura type epiphyseal chondrodysplasia; acromesomelic dysplasia, Maroteaux type; essential hypertension; and myocardial infarction. Orthologous to several human genes including NPR1 (natriuretic peptide receptor 1).
npr1 Enables guanylate cyclase activity; natriuretic peptide receptor activity; and peptide hormone binding activity. Involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Part of receptor complex. Implicated in myocardial infarction.

NR:

description
PREDICTED: atrial natriuretic peptide receptor 1-like

GO:

id name namespace
GO:0035556 intracellular signal transduction biological_process
GO:0006468 protein phosphorylation biological_process
GO:0006182 cGMP biosynthetic process biological_process
GO:0016021 integral component of membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004383 guanylate cyclase activity molecular_function

KEGG:

id description
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007228521.3 True 6675 mRNA 0.45 22 15465492 15582858

Neighbor

gene id symbol gene type direction distance location
mylip mylip,mylipa,LOC107754815,LOC107731572,LOC107694366 coding upstream 31026 15400923 ~ 15434466 (+)
jarid2 jarid2 coding upstream 205828 15077544 ~ 15259664 (+)
sdhaf3 sdhaf3 coding upstream 1100815 14350057 ~ 14364677 (+)
col28a1 NA coding upstream 1126090 14301910 ~ 14339402 (+)
LOC111195557 NA coding upstream 1476554 13987037 ~ 13988938 (+)
ints3 ints3,LOC107754816 coding downstream 9585 15592443 ~ 15611187 (+)
LOC103028143 LOC108273188 coding downstream 32315 15615173 ~ 15632584 (+)
LOC103028648 LOC108435516,LOC108273190 coding downstream 51106 15633964 ~ 15645496 (+)
skiv2l skiv2l,LOC107754802,LOC107677455,LOC107711323,LOC107694354 coding downstream 83780 15666638 ~ 15695499 (+)
prrt1 prrt1,LOC107677474,LOC107694357,LOC107595589,LOC107584308,LOC107711307 coding downstream 116867 15699725 ~ 15709451 (+)
G197747 NA non-coding upstream 71814 15388554 ~ 15393678 (+)
G197716 NA non-coding upstream 110255 15299612 ~ 15355237 (+)
G197663 bloc1s4,LOC105910270,LOC108410562,LOC107731556,LOC107598233,LOC107672822,LOC108272578 non-coding upstream 674282 14789870 ~ 14791210 (+)
G197662 NA non-coding upstream 679752 14785121 ~ 14785740 (+)
G197639 asns,LOC107672863,LOC107754811 non-coding upstream 692030 14771795 ~ 14773462 (+)
G197848 sacm1l,LOC108435519,LOC107595621 non-coding downstream 238620 15821478 ~ 15842757 (+)
G197879 NA non-coding downstream 562653 16145511 ~ 16146073 (+)
G197881 NA non-coding downstream 563627 16146485 ~ 16148110 (+)
G197880 NA non-coding downstream 606054 16188912 ~ 16199486 (+)
G197903 znrd1,LOC107694346,LOC107584303,LOC107754832,LOC107677479,LOC107595594 non-coding downstream 643709 16226567 ~ 16228218 (+)
G197665 NA other upstream 668764 14794420 ~ 14796728 (+)
tac1 tac1 other upstream 996610 14466265 ~ 14468882 (+)
rpa3 NA other upstream 1172424 14276791 ~ 14293068 (+)
G197334 LOC108441809 other upstream 2102834 13324386 ~ 13362658 (+)
s100a14 s100a14,LOC108442988 other upstream 2501143 12956670 ~ 12964349 (+)
LOC103030137 prrc2a,LOC101471845,LOC102784426,LOC102311189 other downstream 179065 15761923 ~ 15789854 (+)
ppp1r11 ppp1r11,LOC107694341 other downstream 739084 16321942 ~ 16330240 (+)
atat1 atat1 other downstream 762259 16345117 ~ 16359668 (+)
c23h5orf49 cunh5orf49,LOC103039620 other downstream 805950 16388808 ~ 16393498 (+)
LOC111195522 LOC107679107,LOC107679108 other downstream 841759 16424617 ~ 16430534 (+)

Expression


Co-expression Network