LOC103040103 (hrasb,hras,LOC107596435,LOC103357265,LOC107562835)


Basic Information

Item Value
gene id LOC103040103
gene name hrasb,hras,LOC107596435,LOC103357265,LOC107562835
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NW_019172830.1
NCBI id APWO02000048.1
chromosome length 5891159
location 689257 ~ 701417 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022665265.1
TCGAGTTGGGAGCCTGGAGCCGGAGAGAGCGAGACTGAGCTAGCAAGTCGGTTCCAATCCGGTATAAGTCATGAAAAATCCGAATTTTCGGGGCTGGTCGTGATTGGAGACGGCGAGGAAAATGTTGACACGCTATTAGCACGCTTTTAAACCGGGTTACAGCTGATATAGCATCATATTTACTGTCCTCGAGGaggaaaacagacagacagccaTTGTATTTGtgttgTGTGGTGGGGCTGTGAGGATGACGGAGTATAAGTTGGTGGTGGTTGGAGCTGGAGGTGTGGGTAAAAGCGCACTGACCATTCAGCTGATCCAAAACCACTTCGTTGACGAGTACGACCCTACCATTGAGGACTCGTACAGGAAGCAGGTGGTGATCGATGGAGAGACGTGTTTGTTGGATATTCTGGACACGGCGGGTCAGGAGGAGTACAGCGCTATGAGGGATCAGTATATGAGGACAGGAGAGGGATTCCTCTGTGTTTTCGCTATTAACAACACCAAGTCCTTTGAAGATATTCACCAGTACAGGGAACAGATTAAGAGAGTGAAGGACTCTGATGATGTGCCCATGGTGCTCGTGGGTAATAAATGTGATCTCCCGGCGCGTACGGTCGACACCAGGCAAGCCCAGGAACTGGCTCGCAGCTACGGCATCCCTTACATCGAGACGTCCGCCAAGACCAGACAGGGAGTGGAGGATGCGTTCTACACGCTGGTGCGTGAAATCAGGCAGCACAAACTGAGGAAGCTGAACCCGCCGGACGATAACGGACAGGACTGCATGAACTGTCGCTGTGTGGTGTCCTGACTAGGTactgcgctgctgctgctggaactGATTTTAGGAGCAGTTGTTCTGCTCCAGAACTGCGTTCGATGCCTCAGCCGATGTTAGGAGTTGGGCACGGACTGTGTGAAGGGAAGCTCTTAACGTCGGCACTCGTGGGTTCGGCTCGCGCCGCCCGCTGAAGAACATCTCAGATCCTGTGCGGACTTTTCCAGAACCGGAGGAAAAGAACTTTACCTCAAACACTGGACTCCCTGCGGACTGTGCTACAGACTGTcacactaaaatataaatatatatattatctgttCTAATAACACACTATCTAGTCTCAACTGGACACAAAAAACTAATATAGCTGACTGCATAACCTcacatgtgtatatatgtatatata

Function

symbol description
hrasb Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Costello syndrome; autistic disorder; carcinoma (multiple); epidermal nevus; and large congenital melanocytic nevus. Orthologous to human HRAS (HRas proto-oncogene, GTPase).
hras Enables GTPase activity; guanyl ribonucleotide binding activity; and protein C-terminus binding activity. Involved in several processes, including positive regulation of MAPK cascade; regulation of GTPase activity; and regulation of protein localization to membrane. Located in several cellular components, including Golgi apparatus; cytosol; and nucleoplasm. Is active in glutamatergic synapse. Implicated in several diseases, including Costello syndrome; autistic disorder; carcinoma (multiple); epidermal nevus; and large congenital melanocytic nevus. Biomarker of Alzheimer's disease; endometrial carcinoma; glioblastoma; liver disease (multiple); and urinary bladder cancer.

NR:

description
-Ha-ras Harvey rat sarcoma viral oncogene homolog b

GO:

id name namespace
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0006184 obsolete GTP catabolic process biological_process
GO:0016020 membrane cellular_component
GO:0003924 GTPase activity molecular_function
GO:0005525 GTP binding molecular_function

KEGG:

id description
K02833 HRAS; GTPase HRas

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022665265.1 True 1193 mRNA 0.50 6 689257 701417

Neighbor

gene id symbol gene type direction distance location
LOC111191160 NA coding upstream 190255 483770 ~ 499002 (+)
LOC103024613 dh12b,hsd17b12b,LOC108414037,LOC107757588,LOC107701268,LOC107695363,LOC107730274 coding upstream 428236 232806 ~ 261021 (+)
ttc17 ttc17,LOC107600454,LOC107695362 coding upstream 498769 167671 ~ 190488 (+)
vps33b vps33b,LOC106587690 coding upstream 535509 138255 ~ 153748 (+)
hypk hypk,LOC107596440,LOC107695358 coding upstream 562669 124276 ~ 126588 (+)
LOC103023516 brsk2b,LOC108444143,LOC107600443,LOC107730259 coding downstream 163816 865233 ~ 950940 (+)
LOC111191156 NA coding downstream 525175 1226592 ~ 1229189 (+)
LOC111191157 NA coding downstream 636354 1337771 ~ 1340796 (+)
LOC103044962 LOC108259203 coding downstream 682923 1384340 ~ 1413595 (+)
LOC103021976 LOC108438545 coding downstream 717619 1419036 ~ 1429239 (+)
G299028 NA non-coding upstream 38050 633841 ~ 651207 (+)
G299006 NA non-coding upstream 189642 499215 ~ 499615 (+)
G299003 NA non-coding upstream 216154 470862 ~ 473103 (+)
G298997 NA non-coding upstream 249140 439913 ~ 440117 (+)
G298903 NA non-coding upstream 358141 296203 ~ 331116 (+)
G299057 NA non-coding downstream 34947 736364 ~ 737381 (+)
G299071 NA non-coding downstream 68703 770120 ~ 771703 (+)
G299072 NA non-coding downstream 68882 770299 ~ 770603 (+)
G299079 NA non-coding downstream 92956 794373 ~ 795114 (+)
G299169 NA non-coding downstream 149268 850685 ~ 851083 (+)
G299000 apip other upstream 218637 462414 ~ 470620 (+)
prc1 prc1 other upstream 523160 154965 ~ 166097 (+)
G298859 NA other upstream 610577 78480 ~ 78680 (+)
LOC111191161 NA other upstream 622070 52791 ~ 67187 (+)
G299046 NA other downstream 3743 705160 ~ 706824 (+)
G299226 NA other downstream 516392 1217809 ~ 1218106 (+)
G299236 NA other downstream 623003 1324420 ~ 1324854 (+)
LOC103047296 NA other downstream 861421 1562838 ~ 1567078 (+)
G299477 NA other downstream 1485916 2187333 ~ 2204255 (+)

Expression


Co-expression Network