LOC103030333 (lis1a,pafah1b1,LOC103030333,LOC102225619,LOC103155189)



Basic Information


Item Value
gene id LOC103030333
gene name lis1a,pafah1b1,LOC103030333,LOC102225619,LOC103155189
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035897.1
NCBI id CM008300.1
chromosome length 26953843
location 25586779 ~ 25624804 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007245916.3
GAGTGGAGCGCGTGCGCTGTGCTCTGCTGCGTTCAGCCTCTGGGGCGGCTCAGCCAGGCAGCTCGTGCGCATGCGCGGTTCATGCTGGCGAAGCCTGTGGAGGAgctaaagcagcagcagaagagccGAGCGGAGCGGAGCCGAGCGGGACAGACCGACTGACCTCACCAACTCCTCCACCGCGGTTTACctgctctcctctctctctgccgcGCCCTGTGGATATTTACTCAGCGGCGGCGCAGTGTAGGATGCAGTGACAGTCTGGCCAGTGAATGTCTTCAGACTGTCTGTTTGTGGTGTTCCTGCAGCGAGTCTATCAAGGGAAGGGTACGTTTTGAGTGGTAGACCTCCCTGTGAGCCGGAGCCGGTGTCCTATTGGTCATCTCCTGCCAGGGAGACAGCAGCTGCTGCACGCCCTTCACCTgacccccctccctccccaccGCCACCATGGTGCTGTCACAGAGGCAACGAGATGAACTAAATCGAGCGATAGCTGATTACCTTCGTTCCAATGGATATGAAGAGGCATATTCAGTTTTCAAGAAGGAAGCAGAATTAGAcatgAATGAGGAGTTGGACAAGAAATATGCTGGCCTTTTGGAAAAGAAATGGACTTCAGTCATCAGATTGCAGAAGAAGGTGATGGAGTTGGAATCAAAGCTGAATGAAGCACAAGAGGAGATCACTTTAGGGGGGCCTATAGCACAGAAACGAGACCCCAAAGAATGGATCCCCCGTCCTCCAGAGAGATATTCTCTGAGTGGCCACAGAAGTCCTGTCACCAAGGTCATTTTCCACCCCGTATTTAGTGTAATGGTGTCCGCGTCGGAGGATGCCACAATTAAGGTATGGGATTATGAGACGGGAGACTTTGAGCGGACCCTCAAGGGTCACACAGACTCTGTGCAGGACATCTCCTTTGATCAGACTGGAAAGCTGCTGGCCTCCTGCTCTGCAGACATGACCATTAAACTCTGGGACTTCCAGGGCTTTGAGTGCATCAGGACCATGCATGgACATGACCATAACGTTTCGTCTGTAGCTATAATGCCCAATGGAGATCATATAATATCTGCCTCTCGAGATAAAACCATGAAAATGTGGGAAGTTGCTACAGGATATTGTACCAAGACATTCACTGGCCACAGAGAGTGGGTACGCATGGTACGACCCAACCAGGATGGCTCCCTGATTGCCAGTTGCTCTAATGACCAGACAGTGCGTGTGTGGGTGGTGGCCACGAAAGAGTGCAAGGCTGAGCTGAGGGAGCACGAACATGTAGTGGAGTGTATCTCCTGGGCCCCTGAGAGTGCCCATCAAACTATAATGGATGCCACTGGCTCTGAGACTAAGAAGAGTGGGAAACCTGGACCGTTCCTGCTGTCTGGCTCCAGAGACAAGACTATCAAGATGTGGGACGTCAGCATTGGCATGTGCCTTATGACGCTGGTTGGCCATGATAACTGGGTGCGCGGTATGATGTTTCACCCTGGTGGAAAGTTTATCATAAGCTGTGCTGATGACAAGACTTTGAGGATCTGGGACTACAAAAACAAGCGCTGCAAGAAGACCTTGAGTGCCCACGAACACTTTGTTACCTCTCTGGATTTTCACAAGGCTGCTCCCTACGTGGTCACCGGAAGTGTAGATCAGACAGTAAAAGTGTGGGAGTGTCGCTGACCTTGCCTGCAGGAATCCACAACCACCACAGCCCTTCACCCCAACCCCTTTTTTCCGTCTGCTCTGGATGCACTTGACCACCATGGTTATGACCCACCCAGCTCTGGTTCAATAACTattgtccttttatgtaaattaTTCTGGATGTAGGTCGAGCTATTAAATGTTACACActcaaaaaaaagtattcttgCATGGTGAATCCAAAATTGTATACTGTAAATTTACATAACGTTGTCTAGAATTACCATAGGTTTAACACAGGCTGACCTTTCACTCAGCCTTACCTACCGAAGGCGTAAACTGACTGGGTTAATGTAGGGCACTATACTGATAATTTAATGACAGTGTCGTCCTTGTTTGtactttaatttcttttctttttttttcttttataaatgtaaactttttttccctcttttgtcatttttttctatCACTGTCGTAGTCTGTTGGTGCCTAGCTTGGTGACCTTTTGGGGAGGGAGGGAAGACAACAAGGTAATACCAGAATACCATTAATCcctaaaaaaaagaggaaaaattgATCGTCTGTGGGGCTTGTTATCAGAATAATCTGTAGCTTTGTAACATCATTTCTGAAGTGTGCTTACTATTCATTCTCTTATTGTGGAACTAGATGATATTTTAATGACTTCATCTAAGAACGATTGAGAGAGTTCTTCTCTTCTTGAAACTTTAGGGGATCAGTCTTTGTACACTTGTCATGAAACGTCCTACTGAGATGAGTATCTGAGTTCAGAAGCTAATTTTGCTTTGCTGGGGAGATTTCCACCTGTTTCTGAATAGACCAGGCTGAAAAGTGGGCAGcaagattttaattttatttttttcttccctaaaTTAAAGTATAGGCCATGTGTGTGTTGGACTATTTTGACCCCATATTAGTGCACTTCAAACATTTTTAGCACCAAAAAAGGGTTGCCTCAATGGAATATTGGTGCTCTGACAGTGTAGTATTAGTTTAAAgagatttatttctatattgcaaaaatatttttttgttttgtttctactCTTAAAAAATCATGTACACCTTGTCTTGTTGCCCCTTTTAGCAGACGATGAAgttgaagtttgcaaaaatgCAAAGCAGTGCAAAAGAAACCCTCCGTTTGGACTTGTGGAGATATAAATGAAGCATGACAAGGGTTCAAAGGGTTTCCTAGTGGTGGGTAAGGGATGTGCAAAGTTCAAACCTGCCTTGATAAAACAGCGGGTTTGTATTGTCGaatttacaaaaatgggtgGGTGGTGTAATCCTTGTGATAAATTGAGAGCTGGGATAGCTACTGTACGCTCAATTCTGTACTGACTGACTGGCTTGTGGGTTATTTAAAGGATGATTCTAATGAAAAGCATATTGTCTGGCTGCCTGAGCTCTCTGTGGAAGTTATGCTTGATGGTGGTAGCTCGTATTTTCCTCCATTTCATTGTAGACAGGACAGTTTCACAGTGTAGACTACAGCAGCTCTATCTTGATCCAGTGAAACATAGACAGGAGTAGAGAGTGCTGGGAACACGTGGGATCAACCTGAAATGGGAGAGCACCTCAAGTTCAAGTTTGAGCAATGCCTGATATTACTAATGTCTTACGAGTAGCACATTCTCTGCTGTTCATCTTGCAATGTGTGTGGGTCAATGTggataaacaaacacactatTGTCCCAGTTAATGAATAGAGTTAATGGATCCCAAAAGTGGAGGTAAACCATTCCATATTTTGAGAATTAAagtaaggaaaaaagaaagaaaaagtaagtaACCTGCCTTTTGTTTTTTGGCAGCAGACTGAAAATGTtggggaaaagaaaaaaaattgaaaattacggtaatgaggaaaaaaaaaaaaactaacttgcACATCCCTCATGTTAGATCTTCTGTCCTTTCTGACTGAAGGTTTAAGCAATTTAAGACTtattaataaatgcataaagAGATCATTTTAATTAGCCTTTTCATTACaatgcaattattattatataataaagaatTCCACTGCTTAACCAGTCTATTATCTAGCGATTTTCCTGTTCCTGTGTGTGTACTGGATgtacctgctgctgctgaaaacCTGATAGTGGCTAGTCTGAGATCTGTACCTGTCGACATAGCACTGCTGCATGTAACAGTACTGAGTACTGGTTGAGCTGTCTGGTGGGGGTCTGTGGTGGTCCAGGTAGTACCGTTGGAATGCGGTGACTAATCTCAGGCCGTCCTGCAGTGTCTTAACTAAGCGAAACAGTCGATTTTTCCTCCTGTaaagaaaaatggaagaaaatctTAGTTTCTTTGCTCGTGACTGGTTTAGGGGATAtctgtgtataatatatatgtactaGTGCTGTTAAACTACGTATTTAATGACTCCAAACACAGACGCCCTACCAGATAGGCCACCTGGCATGATAACTGTGATGAGCTCAGTATGTGGTTGTAGGCAGactggtcagtgtgtgtgtctgtgcgctCTGTGAAGGAGGTTGACTCCTCTGTCGTCTTTCTTTTTGTGATGGGATTGCGGCAGACTGAGGGAGAAGTGCCCACCCCAAACAAAACACCGTTGATGCCTCCTGTAAAGAATATGtaggaaagaaaaaacacagcttGCTATACATTACGATAGTCAAATCGTCCTGTTTAGTTTCTTGTACCTCTTGGACAGAAAGTGGCCCCTAGTACGGTGGGGCCTGTCTTTTACTCAAGGACACAAGCAGGTTAGACTATGCTCTTAAGGGTGTATTCCAGCACCTGGGcctataccaaaaaaaaaaaaaaaaaaaaacagcaggggGATTTTCCTATTGGACAGTTTTTATATATCcgtctatgataactccaaaaTCCTGCATTGTAAAATACTGTACCCAGACCCAGGTCTCACAGGAGATCATGACTTTTGCTCTTATTCACGGTGTGCACAGCTGATGCTCAAAGGAATACTTCCTTATAAAGCGCTACTCCCTCCTGATTGGCAGATTCAAGTCTAACCCAAATTCAGGACTACCTGAAAACATACCTTGCTCTAAAATATACCTTGCGTTTCTTGGTTCGCTAAGAAAAGGCAAAGAATATAAGTGACTCTTGGACACGGTTTTCGACACGTCACCGCGTGAACACTCGCTTTGTGGGTACCAAGGGGTTCCCAGCGTGCCCTGCAAGGAAATTGCGTTTGCCATTCACAGGTCCCAAGCAATCCCAACGCTGCACTCACTGGATGGACTAATGTACATAATATTATTTGTGGGTCCCTCCTCCAGCCACAAGTTCATCTTTCAGCTCTACTTGCTTTGTGAATAGATGGGAGGCTTCAGTCTTCACAGCTCTAATGGGACTTTTGCTTTCATGGTTATCACTGTTCACACAGCCAATTGTTAACAATATATCTGGATGTCATTATTGTTTGCAACataattaaagagaaaaaaatgtaa

Function


symbol description
pafah1b1 Enables dynein complex binding activity. Involved in several processes, including adult locomotory behavior; microtubule cytoskeleton organization; and nervous system development. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and nuclear envelope. Part of microtubule associated complex. Implicated in lissencephaly and lissencephaly 1. Biomarker of hepatocellular carcinoma and schizophrenia.

NR:

description
lissencephaly-1 homolog A-like

GO:

id name namespace
GO:0006928 movement of cell or subcellular component biological_process
GO:0030154 cell differentiation biological_process
GO:0000132 establishment of mitotic spindle orientation biological_process
GO:0007399 nervous system development biological_process
GO:0006810 transport biological_process
GO:0005815 microtubule organizing center cellular_component
GO:0005874 microtubule cellular_component
GO:0005875 microtubule associated complex cellular_component
GO:0005737 cytoplasm cellular_component

KEGG:

id description
K16794 PAFAH1B1, LIS1; platelet-activating factor acetylhydrolase IB subunit alpha

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007245916.3 True 5147 mRNA 0.44 11 25586779 25624804

Neighbor


gene id symbol gene type direction distance location
cluh cluh,cluha,LOC107664929 coding upstream 2798 25551222 ~ 25583981 (+)
ccdc92b LOC108425871 coding upstream 38384 25530149 ~ 25548395 (+)
LOC103028751 tlcd2,LOC103028751,LOC107585588,LOC107664963,LOC107743747,LOC107592621,LOC107685052,LOC107744789 coding upstream 62324 25482105 ~ 25524455 (+)
LOC103027284 NA coding upstream 189245 25391010 ~ 25397534 (+)
LOC103026515 LOC108425801 coding upstream 199837 25378119 ~ 25386942 (+)
mettl16 mettl16,LOC106581049 coding downstream 1531 25626335 ~ 25676963 (+)
mnt mnt coding downstream 56272 25681076 ~ 25713432 (+)
vps53 vps53,LOC107744780,LOC107664930,LOC107743667 coding downstream 101365 25726169 ~ 25758766 (+)
rflnb LOC108425865,LOC107744779,LOC107664902 coding downstream 134131 25758935 ~ 25762483 (+)
exo5 NA coding downstream 139684 25764488 ~ 25774371 (+)
G6464 NA non-coding upstream 37094 25548738 ~ 25549685 (+)
G6446 NA non-coding upstream 83194 25503002 ~ 25503585 (+)
G6445 NA non-coding upstream 85594 25490214 ~ 25501185 (+)
G6441 LOC108425873 non-coding upstream 112593 25470677 ~ 25474186 (+)
G6377 tsr1,LOC107685058,LOC107592627,LOC107743656 non-coding upstream 266051 25319508 ~ 25320728 (+)
G6514 NA non-coding downstream 171818 25796622 ~ 25797186 (+)
G6516 NA non-coding downstream 174114 25798918 ~ 25799741 (+)
LOC111192696 NA non-coding downstream 239582 25864386 ~ 25888817 (+)
G6567 gosr1,LOC107743674,LOC107690419 non-coding downstream 335677 25960481 ~ 25997692 (+)
G6574 NA non-coding downstream 374413 25999217 ~ 26002978 (+)
LOC103027586 LOC108425877 other upstream 158428 25412194 ~ 25428351 (+)
LOC103022942 LOC106931471,LOC106940241,LOC101067200,LOC107659943,LOC106603438 other upstream 1679305 23876999 ~ 23907474 (+)
LOC103035426 NA other upstream 1739412 23839993 ~ 23847367 (+)
G5871 NA other upstream 1752949 23832236 ~ 23833830 (+)
G5797 srsf1a,srsf1b,LOC103029385,LOC108415197,LOC107587230,LOC107704814,LOC108278759,LOC108278234,LOC107661749 other upstream 2235473 23312512 ~ 23351306 (+)
G6576 ywhae,ywhae1,LOC107690422,LOC107578326 other downstream 415352 26040156 ~ 26046246 (+)
LOC103042574 NA other downstream 1294487 26919291 ~ 26931495 (+)

Expression



Co-expression Network