traf4 (traf4,traf4a,LOC108443497,LOC107758738,LOC107727926)



Basic Information


Item Value
gene id traf4
gene name traf4,traf4a,LOC108443497,LOC107758738,LOC107727926
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035897.1
NCBI id CM008300.1
chromosome length 26953843
location 23001851 ~ 23064522 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_015605662.2
CTCCGGGCTGTACCTAAACAGATGGGCTGTGGAGCTTTGTCTCCAGCGTGTCAGTGCTGAGTAGACCGCGGCGGGGGGCGCGCTGTGACCTGGGCCGTAATTCCTGCTGTTCGCTGATTCCCGAGCGGAGAACCGCGGCGGAGGCGCGTTTGTGTGCGGAGAGGAGACGGACTGAGGCGCGGGGAGCGCGGCTAGCTGGGTGAGGCGCTGTCGGTGCCGGTGCGGGGCTGGCTGAGCGGTTGAGCGGTTCAGTGTTTTGTGTAAGCAGAGGAAtaaagagaggaggaggagaaacgctgctggaggaggaggactggagctgctgctgtaggaggaggaggaccGGAGCTGCTGCTGTAGGAGAGCCCGTGCTGCTCCTGTGTTTCTCCTGCTGTTTATTCAGCGCGGACAGAGCAGAGGCGGCTCTCCGCGGCCGGGCTGAGCCTTTGTCTGAGAGGCTGGAGGAGCGACGATGCCGGGCTACGATTACAAGTTCCTGGAGAAACCCAAGCGGCGGTTCCAGTGTCCGCTCTGCAGCAAGGCGATGCGGGAGCCCGTCCAGGTCTCCACATGCGGACACCGGTTCTGCGACACCTGCCTACAGGAGTTCCTCAGTGAGGGCGTCTTCAAGTGCCCAGAGGACCAGCTCCCCTTAGACTATGCCAAGATCTACCCTGAtccagagctggagcagcagatcCTGGCTCTGCCTATTCGCTGTATCCACAGTGAGGAGGGCTGCCGCTGGACGGGTCAGATGAAGCagctgcagGGTCATTTCTCCACCTGCGCCTTCAACGTGATCCCCTGCCCCAACCGCTGTGCCGTCAAGCTGACGCGCCGCGACCTGCCGGAGCACCTGCAGCACGACTGCCCCAAACGCAAGGTCAAGTGCGAGTTCTGCGGCAGCGAGTTCACGGGGGAGGCCTTCGAGaacCACCAGGGCATCTGTCCTCAGGAGAGCGTCTACTGTGAGAATAAGTGTGGGGCACGGATGATGAGGAGGCTCCTCGCCCAGCACACCATGGCCGAGTGTCCGAAACGCACACAGCCCTGCAAATACTGCGGCAAGGAGTTCGTCTACGACACCATCCAGAATCATCAGTACCACTGCCCTCGCTTCCCCGTCCAGTGCCCCAATCAGTGCGGGACCCCCAACATCGCCCGCGAGGACCTGGCCACCCACGTGAAGGAGAGCTGCGGCAGTGCGCTGGTGCTGTGCCCCTTTAAGGACGCCGGCTGCAAACACAGATGCCCAAAGCTGGCGATCGGACGTCACCTGGAAGAGACCACCAAGTCTCACCTGACAATGATGTGCAGCCTGGTGGGCCGTCAGCGGCAGGAGATCATAGAGCTTCGGCGCGAGATGGAGGAACTGTCGGTGAGCCATGACGGCGTGCTCATCTGGAAGCTGAACGATTATTCACGCAAGCTTCAGGAGGCCAAGCTGCACAACAACCACGAGTTCTTCAGTCCACCCTTTTACACGCACCGCTACGGCTACAAGCTGCAGGTTTCCGCCTTCCTCAACGGCAACGGCAGCGGCGAGGGGTCCCACCTCTCCATCTACATCCGTGTGCTTCCCGGCGAGTACGACAACCTGCTGGAGTGGCCCTTCGCCTACAAGGTGACTTTCTCCATCCTGGACCAGAGCGACCCGTCTCTGTCCAAGCCGCAGCACATCACCGAGACCTTCAACCCCGATCCCAACTGGAAGAACTTCCAGAAGCCCTCCAGCAGCCGCAACTCGCTGGACGAGAGCACGCTGGGCTTCGGCTACCCCAAGTTCATCTCGCACGACGAGATCCGCAAAAGAAACTACATTCGTGACAACGCTATCTTCCTCAAGGCTTCCATAGAGATTCCTCAGAAGATCATGGCTTGAGATGGGAAGCCAATGGAAAGCTGGAGAGAAACGCAAATGATTTCATAGGAAGACATTTTGGAACATCTTCCTCACTCATTTCTTAATGATGCTTTTGATGTTTTCCGTTACGAAAACTCAAGTGAAAGACTGGAAAGACTGAGGTTGCCCATGTGGTGGAGGGGCTCCACGAGGAGCTCTACGAGGGGCTCCGTGTCGTCGAAATGTAGGAACGTTGAGGTGTTCTGGTCCGAGAAACCATTGCACGTACTTATTTCAGATTCACCTTTTTCAACACTTTCTCCTCGATTTGCAACGAAAGCCTTTCTCACATTCAATAGTGCCtagaaagttttattttaatttaaaagttgttttaaaataaatgtgatttatgGTCATTCTGTGACAGATGTTAAGTAAACGGTAAGAGTTTTAAGGAGGGTGTGAAAGGTTATTTGTAGCCTGATGTTTGAGCTGTGTTTGGGAACAAGGCAGCAGTGCTCTAGATACACATGGGCAGACAGAACCTGTGTGGTCTGTGTTAGGAATTCAGTGTAAACACTCAAACCCGTTTGCCTTTCGTTTACATTCGCTCCCCCCTCAGCGACGGTCCCTGAACTGTACCTCAGTGACACGAACTGCGGGACCTCGCTTTCCTGTTTACctacttttaaataaactaatagcAGCTGTGAAGTAAACATGTCTCACTTGGACACATTCTGTCACCGAggccctctctgtctctcagtctctcaaACTGTCAAGATCCcagtctctcagtctctcaatctctcaatcTTTTAGTGTCTCAAGATCTCAATATCTTAATCTCCTAATCTCTCAAACTTTTAGTTTCTCAATCTttgtctctcagtctctcaatctctcaacTTTTCAGTCTTTCAATCTCTTAATTTCTCTAATTTTCAGTCTCTCAATTTCTCGGTCTCTCAATCtcttaattttgcaatctgtcaGTCGCTCAACCTTTTATTTTCTCAATCCCTCAGTCTCTTAACCTTTCATTCTCTCATTATCTCAATATCTTagtctctcaatctctcaattTTTCAGTATCTCAATATCTTAGTCTTTCAATGTCTCTGTCTCCGTCTCTCAATTTCTCAATGTCTCATTCTTTCAGTATCTCAAACTCTATTTCTCAGTCTATCAATCTCTTGTTCTCTCAGTATCTTAGTCTCTCAATCTGTCAGTCTCTCAGTCTCAGCTTTTAGTTCTAAATGTTGTTCCAGAACATAAAGCTCGTTTGGGGAAGTTTTCACGACACCTTATTAAAGGCGCGCTCAGGAGAGTTGCATTCCTGGGTGTGTGATGGGGCCAGTGTGCTAATGTGTGTCTCAGGCTCTACAACCAGTCCTCTGCAAGTGAACTGATGCactcatttgtgtgtgtgtgtgtgtgtgtgtgtgaagagaaaGCCATCGATGTGAGAACTTTAAGTTTACATGCAGTGTTGGTTGAGAACTGGGAGGACTCTGGGTGGTGTGGTTGTTAGGGGATTGTTAGAGATGTCCCACTCAAggcctgtttttatttatttgaatggaAGGATATTGGCTATTTTAAGCCAGATAAAACCCTGATTCTTAGTTAACACAGTTTAATCCcattgtactgtatgtaaacatTACATGTTACATGTAACAAAAAGGGCATTCTTTAGAACTTAGGAAAAAGAGGCATTATAACAAGACAAGCAGTTTTCACTGTTTAAAGCCAAGAAAAGGGAGTAGCATTGGTTACAGGGTACGTATGCTGGTTGGTTACAGGGTAGAAATGCAATGATTCTCTGACCAATTATTGTCTGTATTGATTAGATTACTAGCAAAAACTGATATTTGCAGGTATTAGATTATTAAGGGCATGTAAACACACTTAACGAGACTAGCAAACTGGTGTAGCGAGGTGTATAACATTACACTACACCAACAATACATCCTAACCTAATTATGTAACATTattccaaatgttagacactCTAGATAAAAGTGGCAGTCAGAAATGCTATGAAATATTGCTATAAAAATGCTATAAAAGTTCAGTTCAGAGTGTGTCACACTATGCAAATACTGAAAATAcctgattttactgtagcataTAACAGTAGCTGAGCTGTTTTGGGATGCATTGATATGTGTAGTACGAAAGTGctaatatatacacatttatatatttatatggtgCTAAATGTCCCTGGATTAGTATTATCTACAAACAGAACCATtgattaacctttttttttttattaataaaatgaattaattaagcCTAAGCACCTAAGCACTTCCAGAGTTAAATAAATACTAGTTTGAAATATCAAATCAAGAATTTGTTCTTATAAAAAGTCAGCAAAAATTCTGCGTCACATTTGTTATGTGTATTATAGCAGCTATGCTCTTATAactggacacatccaggtagctgcactgttaaaatagcaatctgccaaagtcagagcacacctttgttttaaagggaatggcaagtgacattctgattggtttatttcacgttacgcccaaaacacatccatgataattgagagaattagtgcatgccttttgcacgtttcgagtcgagcaaggtgtacttttcccatcgttatgatagccaCACTCAAGATTAATAAAATAGGGCCATAGGCCTCTTAGGTTGGGATGGGATGAAAGCCTTGATTGGGACATCTCTCTACTGATGGTTGAGATCAGATCAGTTTGTGTATTGAGAGTTTATGCCACAAATTTGTACTGTAACCTGTTCTCTTGAAACCTTGAAACTTTTCATTGGGGGCATTTTTATTGCATCGGGCGGAACCACCACACGGAACCAAAATCTTCTTTTataaggaaaaagaaaggaacTAAATGAGCTAAAGCGCGTAGGACAAGTGAGACCTTCAGACTTCAGACTTTCTGTTGCATGTTCTCCTTATCGGACTCTaaactgaagagagagagagagagaaagagagagagagcgaggaggTGTGTTGGTTCTTCAGGTGGAATCTGAGGAGCGTTCCTCTGCGTACCTGAGGAAAGACGAGCTTCGTGCAATATGGCTGCCATTTCTCCCCACAGACAAAGCATTAGAGCATCGGAGGAGGACTGTGGATAACTGAATAACTAAACATGTGATTTACTAATAGACATGCGGAAGCACATTCTCATCTTACGTCTTactcttcttcatcatcatcatcaaaaagAAGTCCTGATTTAATCGCGCTATAATACCAGCtaatattttcacaataactttgagaaaatgtggattttttttcaagattctgtATTTTACAAGCGTACTTTCCAGATGTTTTATACAACACTTTTTTTGAGGAGAGGTAGGGAGCTGTATTTGGACGTTTCCTCCGTTTCGGTCTCTGGAACTTTCTCCATCGTTCATCGTTCCGGTTTGGATTTTTTGCATACTCTGTCTGTACTATACGCTCttgaaaagtatttattttaagccATCACATAGACTCCGAACACAGGATGGCgcaaatgtttttatatgtttttgtttgatttgtttgacgactgcttgtcatttttctcctccttgaaataaaataatgtccAGAG

Function


symbol description
traf4a Predicted to enable tumor necrosis factor receptor binding activity and zinc ion binding activity. Acts upstream of or within establishment of epithelial cell apical/basal polarity; optic cup morphogenesis involved in camera-type eye development; and optic vesicle elongation. Predicted to be located in cytoplasm. Is expressed in several structures, including axial blood vessel; digestive system; immature eye; mesoderm; and nervous system. Orthologous to human TRAF4 (TNF receptor associated factor 4).
traf4 Enables several functions, including WW domain binding activity; enzyme binding activity; and tumor necrosis factor receptor binding activity. Involved in positive regulation of JNK cascade and positive regulation of protein kinase activity. Located in cytosol; fibrillar center; and nucleoplasm.

NR:

description
TNF receptor-associated factor 4

GO:

id name namespace
GO:0042981 regulation of apoptotic process biological_process
GO:0016567 protein ubiquitination biological_process
GO:0007165 signal transduction biological_process
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K09848 TRAF4; TNF receptor-associated factor 4

RNA


RNA id representative length rna type GC content exon number start site end site
XM_015605662.2 True 5481 mRNA 0.46 7 23001851 23064522

Neighbor


gene id symbol gene type direction distance location
nek8 nek8,LOC107672375,LOC107758702,LOC107592757,LOC107661116 coding upstream 3569 22975520 ~ 22998282 (+)
LOC103023064 zgc:174895,LOC103023064,LOC107672400,LOC107657114,LOC107752376,LOC105911024,LOC108278204,LOC106612798,LOC108443501 coding upstream 55247 22940729 ~ 22946604 (+)
LOC103021948 LOC107694033 coding upstream 76335 22911025 ~ 22925516 (+)
LOC103043000 LOC107694033,LOC107592755,LOC107752375,LOC105911027 coding upstream 84011 22910951 ~ 22917840 (+)
LOC103042688 LOC107694033,LOC107592755,LOC107752375,LOC105911027 coding upstream 92220 22904775 ~ 22909631 (+)
tada2a tada2a,LOC107661114,LOC107755391 coding downstream 93992 23158514 ~ 23177559 (+)
dusp14 dusp14 coding downstream 126568 23191090 ~ 23202017 (+)
mrm3 NA coding downstream 352617 23417139 ~ 23421491 (+)
LOC103033181 LOC108411674,LOC108277977 coding downstream 467328 23531850 ~ 23544221 (+)
LOC103034256 flot2,LOC108411680,LOC106581211,LOC105011286,LOC106612814,LOC107727921 coding downstream 499826 23564348 ~ 23580240 (+)
LOC111192542 NA non-coding upstream 26904 22967991 ~ 22974947 (+)
G5642 LOC108443500 non-coding upstream 43352 22956060 ~ 22958499 (+)
G5640 rab34a,LOC103022556,LOC108443499,LOC107758713,LOC107672399,LOC107657101 non-coding upstream 50176 22949827 ~ 22951675 (+)
G5628 NA non-coding upstream 96196 22905138 ~ 22905655 (+)
G5619 NA non-coding upstream 177785 22822871 ~ 22824066 (+)
G5736 NA non-coding downstream 12635 23077157 ~ 23077356 (+)
G5762 NA non-coding downstream 149169 23213691 ~ 23215367 (+)
G5768 synrg non-coding downstream 181610 23246132 ~ 23248019 (+)
G5801 dynll2a,LOC107554284,LOC103397138 non-coding downstream 270594 23335116 ~ 23339774 (+)
G5804 NA non-coding downstream 288215 23352737 ~ 23354154 (+)
G5646 NA other upstream 36927 22964060 ~ 22964924 (+)
G5620 LOC107694033,LOC107752375,LOC107592755,LOC105030986 other upstream 78770 22902766 ~ 22923081 (+)
LOC103045948 grm5b,LOC108411478,LOC107670133,LOC107737424,LOC107731813,LOC107669866 other upstream 243638 22708912 ~ 22758213 (+)
LOC103041654 chordc1,LOC108412466 other upstream 327867 22642610 ~ 22673984 (+)
LOC103043812 gria4a,gria4,LOC107725765,LOC107670112,LOC107689577,LOC107566895,LOC107560842,LOC107756206,LOC107756230 other upstream 477105 22407556 ~ 22524746 (+)
LOC103024639 NA other downstream 16869 23081391 ~ 23156366 (+)
G5797 srsf1a,srsf1b,LOC103029385,LOC108415197,LOC107587230,LOC107704814,LOC108278759,LOC108278234,LOC107661749 other downstream 247990 23312512 ~ 23351306 (+)
G5871 NA other downstream 767714 23832236 ~ 23833830 (+)
LOC103035426 NA other downstream 775471 23839993 ~ 23847367 (+)
LOC103022942 LOC106931471,LOC106940241,LOC101067200,LOC107659943,LOC106603438 other downstream 812477 23876999 ~ 23907474 (+)

Expression



Co-expression Network