CI01000012_02251322_02337964 (PRKG1A, PRKG1, PRKG1B)


Basic Information

Item Value
gene id CI01000012_02251322_02337964
gene name PRKG1A, PRKG1, PRKG1B
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000012
NCBI id null
chromosome length 13770000
location 2251137 ~ 2339368 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000012_02251322_02337964.mRNA
ACCCATTCATCAGGAGGGGGATGAAGAGCCACATTGATTTTGGGGACTGCATAGCAATTGTTTTATCATTGTTTGAGCGTGTGGATAAAACACATTAAAAACACAAAATGCATTTCATTGTTTATTATTATTATTATTTTTTAAATAATAGGCCTATATTATATAGCCTAGGTATAACTGTGTAGTTTATCTCAACCAATGTGATATCAGTGTTAAAACACCGCGGATAGTTGCAATGCATGTCTTCTCTTGGCATTAACGATAGGGAGTCTGATTCATTTCAGCGAATCGGTTCGTTTCATAGAAGATGTTCAATAAAAAACGATTCAGCAGTTAGTCATCACGTTCCTTGATATTCCAGCGTGGCATATAATACTTTAAAACCACAAAAAGATTTCTTTTTTATTTAATTAAGATGTATTTTTTACTGTTATTTATTGTGTCCTAGTTCAGTTCATTGCAGCCATGATTCACTTAATAAATATAAAATATAGCCTACTAAATATAATTTGCATTTACATAGGCTTACATTTTAACAATAGCCTATAATTCATCCCCTGGCTGAAAATGTTTTGCTATGCTATTTATTTTAAACAACTTTGTTTCGTTGTGTGTTGATAAGACTAACTCATTCTGGAGCCTAACATTTCTGTTATTTGGCTATTAAAGTTGGCGTAACTAACTTTTCGCCCCGCCCTCAGTCAAATCCTTGGTACAATCCAAATCATTTCACTCATCGGTTCTGGGTCCATTACGAATCGGGCTTGTTCGAAAAATACCTTTCGTTTCTCGGTTCAGTGAGTCGATAACTGCATTCAACTCTAATGAAAGAGATTGTTCAACCGATTCATTCAAGAGTTCCAAATCATGTTTAACCGATTGATAAGATCCGACTCTTCCGAAGAATGATTCATTCACAAATCGGACACGGCAAGTTGACAAATCGATCAGTGCGCGTGTACGGTACAGTTCACAATACTGTTTCCCACGATTGGGACTCCAGGGTAAGTGCATTTATACAGCCTCTGTGCTTTAAAATGTCCGTGTAATCGCACCTTATCGTGGTTTATGTAGAATATATAGTTTCAGATGCGGCTTCTCATCCCCCCACTTTATTCCCCCTAAGCACCAAAGTGAAACTCCGCCTATGGTGAAGACCCCGTGGATGAGGAGACAGTCTGTACCCGGTATGGTTTGTGTTTTTGGACGGGTATGTTTGTGACACAAGTAGCCTAACCGTCAGCGGGACCGACGCCGACACCCGTTTCCAACTGTAAACACGTGGATAGATCAGCTGTTTTACACTGGAGCTTCACAACCTGAGCTTGTCTGGGCGCGTGATACAGTTTGAGAGCGCGCCTGGTTGATTTCAAGGGGATTAAAGTTTTTTTTTACTACCTCAGAATGAGTGACCTGGAGGAAGACTTTGCAAAGATTTTAATGCTGAAGGAGGAGAGGATACGAGATCTGGAAAGGCGCTTGGTGGAGCGAGAAGACGAAATCAGCGAGCTGAAGAGAAAGCTGCACAAATGTCAGTCCGTTTTACCGAGCGCGCAGATCGGACCACGGACGCACCGCGCGCAGGGAATATCAGCCGAACCGCAAACGCACCAGGATTTATCAAACCAAAGCTTTAGGAGAGTTGCCAAATCTGACAGTCTGACACCAGAGGGCGCCTTATGTCCTTTGATAAACTCAGTCAAACATAATGCATCTCTACTAGCTCTCCAAAGTGGAGAAGGGATGATGATGGGGACTTTACGCGACCTCCAATACGCGCTTCAGGAGAAAATTGAAGAACTGAGACAGAGAGACGCGCTCATTGACGAACTGGAGCTCGAACTGGACCAGAAAGATGAACTGATTCAGAAACTGCAGAACGAACTGGATAAGTACCGCTCCGTAATTCGCCCGGCGACCCAACAGGTCCAAACCCGCTCGGAGCTGCAGGAGCATCAGCGCACCAAACGACAGGCGATCAGCGCCGAACCAGCCAACGTCCAGCAGCTGAGTCACGTGACCCTGCCCAACGTCCCCAAGAGTGCCAAGTCAAAGGAACTGATCAAGTCAGCTATCCTGGACAATGACTTCATGAAGAATCTGGAGATGTCTCAGATCCAGGAGATAGTGGATTGTATGTATCCAGTGGACTATGACAAAAACAGCTGTATTATTAAAGAAGGGGATGTGGGCTCCCTCGTCTACGTCATGGAAGGGGCTGACCCTAGCGTGAGGTTGCCTCTGCAAGTGGCTTCGGCACCGGATTTTCTTGCTTCTAATACTTTCTCCCAAGCTCGATCTCCTTTCACTCTGTTTTCCGCAACACTGATGCCCATCCCACTAAAAGCTACAGCCTTGGAACCACCCCCCGTCACCAGCAACATCAGAGCACAGATGCTCACAGGAGCCCTGTTTCCCATTCCAACTTGCCTCACTGCTGCAGCAGTGTTATCTCTTCTGCTCCCGCAGGAGCTCATTTCTCCATCCAACTTGCCCATTGCACAGTTGGAAAGCAAATTGAAAAGCAAGTTTGCTCCACTGCTGCAGCAGTGTCATCTACTCCGCTCCCACATGAGCTCCATTACACCGTCCAAACTTGCTCCACTGCCACAGCAGTGTCATCTACTCCACTCCCGCAGGAGCTTGCCCATGCAAGACCATTCTCAGCCAACTACCAGCGAGGCTCACCCATCTGATACCATGACAACCAAACTCCCGTCTAATGATGCAAGAAGCTCTCCCAATCCAGCAACTAACCCCCTCCCTATGACTGGCACACCATCAGCTTTGAGCTCTGCAATTCTTAAAGTTGTGCTCAAAGAGTTGTCAATTTGCTCAGGTCTGAAAAAATTGAGGAACCATTATGGTGACAAGACCAACTGTCTGTGTGATCAGCTGTTGAAAAAGGGAAAGGTTGAAGTGACTAAAGAAGGATTGAAGCTGTGCACCATGGGACCAGGAAAGGTGTTTGGAGAGCTCGCTATCCTTTATAACTGCACCAGGACGGCCACTGTGAGAAATCATCTTATATGCACAGGCTTGTGTGCTGTGAATTATTTGCAAGCATTTCTCTCATTTATTATTCCATTCCTCTTTTCATTTTCTTTTTCCTATGAACCATTGTTCTCCTTCATGCATATTCTCTTCTTGCCTCCGCTTGGCTCTCTTTCTCCATCCTTTTCCCCTTCACTCTATCTCTCCTCTTCCACTCTATCTCTCCTCCTCCGGCTGTGTTTATGGTGTTCCTGCACTCCTCTGCGCTCTGTCTCTGGTTCTCTGGATAGCGTCTGGGACAGGAACTGTGACCAGTGTGAAGTTATGGGCCATCGACAGACAGTGCTTCCAGACCATCATGATGAGGACAGGACTCATCAAACATGCAGAGTACATGGAGTTATTGAAAAGACTCTAGGTGATGTTGGAACAAAGTGTTTGCTTGTGTCAGAGTCTTTCTGGGCATTAGTTTCCTTTCTGCTGGTCATATCTGATTTCAGACTGATGTGTCTGGAGGTCAAGGTCTTAGAGAACAAACTGAGGACACACTATGAAGATGGCGACTACATCATTCGCCAGGGGGCAAGAGGAGACACATTCTTCATTATCAGTAAAGGAAAGGTGACAATGACTCGGGAGGACTGTCCAGGTCAGGAGCCAGTCTACTTGCGTTCAATGGGGAAAGGAGACTCGTTTGGGGAAAAAGCCCTACAAGGGGAGGACATCAGAACAGCTAATGTCATCGCAGCAGAGACTGTCACCTGCCTTGTGATTGACAGAGACTCATACAAACACCTGATTGGAGGCCTGGAAGACGTATCCAACAAAGGCTGTGAAGATGCAGAGGCAAAAGCAAAATATGAGGTGGAGAACGCCTTCTTCTCTAACCTAAACCTGTCTGACTTCAACATCATCGACACTCTTGGAGTTGGAGGATTCGGACGCGTTGAACTGGTGCAGCTCAAGAGTGATGAGGTGAAGACATTTGCAATGAAGATCCTAAAGAAGCGCCACATCGTGGACACGAGACAGCAGGAGCATATCCGATCAGAGAAACTAATTATGCAGGAGGCGCATTCAGATTTTATAGTCAGACTCTATAGGACGTTTAAGGACAGTAAATACCTCTATATGCTAATGGAAGCGTGTTTAGGTGGAGAACTGTGGACTATCCTCCGAGACAGAGGAAACTTTGACGATTCAACCACACGGTTTTACACTGCGTGTGTGGTGGAGGCGTTCGCTTACCTGCATTCCAAAGGCATCATATACAGAGACCTCAAACCAGAGAACCTGATACTAGACCACAGAGGCTACGCCAAACTGGTGGATTTTGGCTTTGCTAAGAAGATCGGCTTTGGGAAGAAGACCTGGACATTCTGTGGTACTCCAGAGTATGTGGCACCAGAGATCATCCTGAATAAAGGACATGACATCTCCGCAGATTACTGGTCCCTCGGCATCCTCATGTACGAGCTACTGACCGGCAGTCCTCCTTTTTCAGGACCAGATCCAATGAAAACATACAACATCATTCTAAGAGGCATTGACATGATAGAATTCCCCAAAAAAATTACCAAAAATGCTGCCAATCTAATCAAAAAACTATGCAGAGACACACCCTCTGAAAGATTAGGAAACTTGAAAAACGGTGTCAAAGACATCCAGAAGCACAAATGGTTTGAAGGGTTTAACTGGGACGGATTGAGGAAGGGGACACTGACGCCCCCCATCATCCCTAATGTAAGTGCTTACGCTCATGCAGGATAGATTTTACACTGATGTTAGGCCAGAAACATACTCTATGCAAGTACACTCTTAGAAGAAAAGGTTCTATATATAACCTTAAAGGGTTCTGCCAGGTGCTTCATATATCTTTTAATTCATTTGTAATTTTAATTACATTTTATGAATTAAGCAGCTTGTAAACACTATCACTAAAAATATATTATAAA

Function

symbol description
prkg1a Predicted to enable ATP binding activity; cGMP binding activity; and cGMP-dependent protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Is expressed in several structures, including heart; nervous system; neural tube; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human PRKG1 (protein kinase cGMP-dependent 1).
prkg1b Predicted to enable ATP binding activity; cGMP binding activity; and cGMP-dependent protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Is expressed in several structures, including female organism; heart; integument; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human PRKG1 (protein kinase cGMP-dependent 1).
prkg1 Enables cGMP-dependent protein kinase activity; calcium channel regulator activity; and identical protein binding activity. Involved in several processes, including negative regulation of platelet aggregation; negative regulation of vascular associated smooth muscle cell migration; and negative regulation of vascular associated smooth muscle cell proliferation. Located in cytoplasm and plasma membrane. Implicated in thoracic aortic aneurysm.

NR:

description
unnamed protein product

GO:

id name namespace
GO:0030553 cGMP binding molecular_function

KEGG:

id description
K07376 PRKG1; cGMP-dependent protein kinase 1

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000012_02251322_02337964.mRNA True 4949 mRNA 0.45 25 2251137 2339368

Neighbor

gene id symbol gene type direction distance location
CI01000012_02239088_02240850 NA coding downstream 10275 2238400 ~ 2240862 (-)
CI01000012_01677949_01691893 POLR1B coding downstream 559101 1677904 ~ 1692036 (-)
CI01000012_01601665_01604244 CYP1B1 coding downstream 646784 1601654 ~ 1604353 (-)
CI01000012_01489297_01490202 CDC42EP3 coding downstream 760824 1488830 ~ 1490313 (-)
CI01000012_01256938_01257273 PRKCE coding downstream 993864 1255717 ~ 1257273 (-)
CI01000012_02357517_02361973 NKX1-2, NKX1.2LA coding upstream 17756 2357124 ~ 2361973 (-)
CI01000012_02381631_02386668 NA coding upstream 41980 2381348 ~ 2386668 (-)
CI01000012_02395816_02404347 HPS1 coding upstream 56189 2395557 ~ 2404347 (-)
CI01000012_02413852_02502617 HPSE2 coding upstream 74484 2413852 ~ 2502617 (-)
CI01000012_02549682_02550094 GOT1, GOT1.S coding upstream 210303 2549671 ~ 2550094 (-)
G70543 NA non-coding downstream 18861 2232039 ~ 2232276 (-)
G70538 NA non-coding downstream 40503 2210342 ~ 2210634 (-)
G70522 NA non-coding downstream 77917 2172939 ~ 2173220 (-)
G70477 NA non-coding downstream 135410 2115231 ~ 2115727 (-)
G70469 NA non-coding downstream 155568 2092870 ~ 2095569 (-)
G70664 NA non-coding upstream 165338 2504706 ~ 2504932 (-)
G70687 NA non-coding upstream 246128 2585496 ~ 2586108 (-)
G70690 NA non-coding upstream 248092 2587460 ~ 2587689 (-)
G70728 NA non-coding upstream 338503 2677871 ~ 2678081 (-)
G70704 NA non-coding upstream 464116 2803484 ~ 2840043 (-)
G69562 NA other downstream 874839 1332075 ~ 1376298 (-)
CI01000012_01139864_01192154 TTC7A other downstream 1099939 1135676 ~ 1192154 (-)
G69332 NA other downstream 1475258 775364 ~ 775879 (-)
G69277 NA other downstream 1520672 729920 ~ 730465 (-)
G69161 NA other downstream 1663122 587604 ~ 588015 (-)
G70774 NA other upstream 527140 2866508 ~ 2866892 (-)
G71898 NA other upstream 2194162 4533530 ~ 4534672 (-)
G72068 NA other upstream 2436852 4776220 ~ 4780132 (-)
G72204 NA other upstream 2954405 5293773 ~ 5302206 (-)
CI01000012_05414096_05416676 TTC9 other upstream 3024274 5413369 ~ 5416780 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_006188 prkg1a coding NC_007124.7 CM002897.2 40815012 ~ 40955599 (+)
bowfin (Amia calva) AMCG00002929 LOC106578950,LOC106589397 coding CM030139.1 CM030139.1 6556470 ~ 6575271 (+)