irf8 (irf8)


Basic Information

Item Value
gene id irf8
gene name irf8
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035914.1
NCBI id CM008317.1
chromosome length 41377133
location 6100753 ~ 6111006 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007243994.3
TGTGAATTGATTCTGAAGGTAAAATAAAGGTGCTGTGAATATTTACAGTAAAGGTTTTTAAATGAGAGAGTAAATCAGCTGGATCCAGAGGCTGGTTAGATGAGTACATGCTGAAGGTTGTAAAGTCCCTTTTCCATGGAAGTGAAGCCCACCCCAGCCGCCTGAGAACCTCCGACTGAGGGAAAGGCGATTTCTTGTAAATGCCTCCGCTTCTAAGAAGTTTTCCGTGCTGGAGGCGTCACGTCGGTGGGCGTGTTTTGATTGGATGCGGGGGAGCGGGGGCGTGGCCACGAGCTCCATTCACACAAAATGAACAGACATACTTTCTTTCCCCCAAAATAAATCTCCTCAGATCTTCAGATCAGCAGTCAGTGCAGAGCATAGTGATCACTGAGCCGAGATGAATCCAGGAGGGCGCAGACTGAAGCAGTGGCTGATCGAGCAGATCAACAGTAATATTTACTCTGGGCTTCTGTGGGAAGATGAGTATCACACCATGTTCAGAATACCGTGGAAACACGCTGGAAAGCAGGACTACAACCAAGAGGTGGATGCGTCCATTTTCAAAGCTTGGGCGGTGTTTAAGGGAAAATTTAAAGAGGGAGACAAAGCTGAACCGGCTACATGGAAGACCCGGCTGAGATGTGCTCTGAACAAGAGCCCCGATTTTGAGGAGGTGACAGAACGCTCACAGCTGGACATCTCAGAGCCCTACAAAGTGTACAGGATTGTCCCCGAGGAGGAGCagaagtTGTGTAAAAGTGCCACCACTACCTTGAACATGAGCTGCCCACCTGAAGGGTCTGAGATGGAGTGCAGTCAAGCAAATACAGACCTAGACAGACTCATTAAAGAGACACCAAGCGACGAATACATGAGCATTATCAAGAGGAGCCATTCTCCAATAGATGAGAACAGCAACCTGCAGTCCCCGCAGGAGTGGTGGCACCAGGGCTCGCCCAGCGctctCCCTATTCTGCAAGATCCTTCACCAATAAATACCTTTAATGCAGCTTTCTCTCAGATGATGATCTCTTTCTACTATGGAGGAAAGCTAATGACCAGCACCCTGATCAGTCATCCAGAAGGCTGTCGGATCTCTCCCGGTCAGCCTCCCATGTCCAACCCCATGGTGTATGGCCCAGACACCCTCCAGAACGTGCGCTTCCCACCCGTGGAGCTCATCGAACACGAGCGGCAGCGCCACATCACCCGCAAGCTCTTCGGCCACCTGGAGCGCGGCGTGCTGCTGCGGGCCAACCGGGAGGGCATCTTCATCAAGCGCCTGTGCCAGAGCAGAGTGTTCTGGAGCGGGCAGGACGCACAGTACGGCCCTGGGCCCAGCAAGCTGGAGAGAGACGCTGTGGTGAAGATCTTTGATACTAGCCGCTTTCTTCATGCCCTCCAGCTGTATCAGGATAATCAGTACCCAGCTCCAGATCCTACAGTCTCTCTGTGTTTCGGGGAGGAGTTCAATGACTTCAGCACAGCCAAGACCAAGCTAATTATTGTGCAGATCACAGCAGTGAACTGCCAGCAGCTGTTAGAAGCAGTGATGACCAGGAGAGCTCAGTACAGCAGCGGCAACCTGGAGATCTCTGACGAGATAGCCAGTGACCAGATGGCTCGCATTTACCAGGACCTGTGCAACTACCCCTCCCAGCGGGCACCCTGCTACCGGGACAACCTGCCCATCACTGCCTGAAGCACTGCCCTGAGATCAGAGCACATCCAGAGCAACTTCACAAACTGACTTAAAGtgacttctttaaaaagtagaCAGTAAAGAAGAGCAGCAGACTCGTAGAAGACTCTTTTACATTTCTTCACAACACGTCTGTAATCATGGCAGCAAGAAGCATTAGCACAACTGCAGTTAGATAAAGCTACATGTAGCACAGTGTTCTCTCAGGTCCTCAGAATGGACAGCAGATTAGAGATGAATCTGAAAATGTTCTCagggaaactttttttttttttttcagttttaaagctTAAAATTTGACAAGAATTCTTGCAAGATGTTTGTGGAATTGCATATGTGACCAATGTATTACGTTTatcctttgtgtttttttttttttacttttctgtaTGAGAGATTGTTTGTTGTGAGATGATAGGTTTTACTATCctggcatttttttattattactcttgaaataaacatttttgtacaaata

Function

symbol description
irf8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within microglia development; regulation of macrophage differentiation; and regulation of neutrophil differentiation. Predicted to be active in nucleus. Is expressed in brain; eye; hematopoietic cell; hematopoietic system; and yolk. Human ortholog(s) of this gene implicated in immunodeficiency 32A and immunodeficiency 32B. Orthologous to human IRF8 (interferon regulatory factor 8).

NR:

description
interferon regulatory factor 8-like isoform X5

GO: NA

KEGG:

id description
K10155 IRF8; interferon regulatory factor 8

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007243994.3 True 2183 mRNA 0.48 9 6100753 6111006

Neighbor

gene id symbol gene type direction distance location
LOC103030962 ds22a,LOC108434600,LOC105892932,LOC106562285 coding upstream 5085 6067215 ~ 6095668 (+)
LOC103031281 cox4i1,LOC103031281,LOC108412231,LOC107663352,LOC107731261,LOC107565335,LOC107572641 coding upstream 35220 6063252 ~ 6065533 (+)
gse1 gse1,LOC107565336,LOC107719882,LOC107661366 coding upstream 58250 5703096 ~ 6042503 (+)
LOC103034771 LOC108442590 coding upstream 459640 5639248 ~ 5641113 (+)
atmin atmin coding upstream 470563 5621220 ~ 5630190 (+)
foxf1 foxf1 coding downstream 190842 6301848 ~ 6305572 (+)
dbndd1 dbndd1,dbnd1,LOC106562278 coding downstream 213815 6324821 ~ 6363149 (+)
gas8 gas8,LOC108276428 coding downstream 371813 6482819 ~ 6488287 (+)
LOC103042367 LOC108435537,LOC105906449,LOC101169526 coding downstream 620164 6731170 ~ 6759468 (+)
zdhhc7 zdhhc7,LOC108435925,LOC107705792,LOC107573093,LOC107736389,LOC107686620,LOC107662857,LOC107601043 coding downstream 697929 6808935 ~ 6817496 (+)
G156326 emc8,LOC106587369 non-coding upstream 38756 6056669 ~ 6061997 (+)
G156331 NA non-coding upstream 48371 6050480 ~ 6052382 (+)
G156233 NA non-coding upstream 452179 5645881 ~ 5648574 (+)
G156225 NA non-coding upstream 489480 5602332 ~ 5611273 (+)
G156215 NA non-coding upstream 499094 5601105 ~ 5601659 (+)
G156340 NA non-coding downstream 6139 6117145 ~ 6117589 (+)
G156395 NA non-coding downstream 195719 6306725 ~ 6307420 (+)
G156397 NA non-coding downstream 197227 6308233 ~ 6308561 (+)
G156399 NA non-coding downstream 198366 6309372 ~ 6309620 (+)
G156402 NA non-coding downstream 202946 6313952 ~ 6317024 (+)
G156188 NA other upstream 943353 5157154 ~ 5157400 (+)
LOC103030011 LOC108433937,LOC108264032,LOC106573278,LOC106561481 other upstream 1463463 4575668 ~ 4637290 (+)
LOC103025196 arl4c,LOC103025196,LOC108425959,LOC108267031,LOC107104020 other upstream 2168590 3929331 ~ 3932163 (+)
LOC111194753 NA other upstream 2486262 3611018 ~ 3614491 (+)
G155776 NA other upstream 3345641 2738361 ~ 2755112 (+)
ptprq ptprq,LOC108413201,LOC107705767,LOC107686600,LOC107564908 other downstream 982501 7093507 ~ 7171625 (+)
LOC111194759 NA other downstream 1261370 7372376 ~ 7431568 (+)
G156840 cd9a,LOC108438826,LOC107686554,LOC107733276,LOC107559685 other downstream 1489561 7600567 ~ 7606668 (+)
G157055 NA other downstream 2458924 8569930 ~ 8570877 (+)
G157383 NA other downstream 3829823 9940829 ~ 9941805 (+)

Expression


Co-expression Network