slc12a3 (slc12a3,LOC107583876)



Basic Information


Item Value
gene id slc12a3
gene name slc12a3,LOC107583876
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035914.1
NCBI id CM008317.1
chromosome length 41377133
location 15808189 ~ 15822339 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007249198.3
TCCAGGTACCATATAACCCTTCCACCCAGCCAGTCCCACCAGTCACATTTTCATCCACTCACTCATGGAGGAGGCCCCACAGTCTAATGAGGTGATCAACCTCACCACGTTCAGAGGCCAGTATTCCATCTCTCCACCAATTTCCAATGGTGGGGACAACCGCAGGTTTGCTGTGGACGAGAACGGTGGTTATGATGTCAATGGAAGAGCCTCTCGCAGTTCTGCGGTGTTGTCTGGATATGATACAATGGATACACCGCCAAACTATGACTTTTATGCCAACACAGAAGTGTTTGGGAGGACACGGAAAATAAGACCATCTCTGTTCCAGCTTCATTCCAACCCTGAGGATGACTCCTCTCCACCTCCCCTGTATGAGGAGACAAGTGGTAACAAGGAGAGCCCAGAGGATGAGCTAGCAGAACCTCCTCCAGAGCCGACTCGCTTCGGTTGGGTACAGGGGGTCATGATTCGTTGTATGCTCAACATCTGGGGAGTGATCCTGTACCTCAGGCTTCCCTGGATCACAGCTCAAGCTGGGATTGGTTTGACCTGGGTTATAATCCTTCTGTCCTCCTGCATCACTGGAATCACCGGCCTCTCCACATCTGCCATTGCCACCAACGGCAAAGTGAAAGGAGGTGGGACTTACTTCCTAATCTCACGCAGTCTGGGCCCAGAGCTGGGGGGCTCTATTGGACTCATCTTTGCGTTTGCTAATGCGGTGGCCGTGGCCATGCACACTGTGGGCTTCGCTGAGACTGTACAGGCTCTCATGCAGGAAAGTGGTACAAGCATGGTGGACCCTTTAAATGACATTCGCATCATCGGTGTCATTACTGTCACCTGTCTGCTGGCCATTTCAATGGCTGGTATGGAGTGGGAGTCAAAGGCTCAGGTTTTGTTCTTCTTTGTTATCATGGTCTCTTTTGCAAACTACATTGTGGGTACCATCATCCCAGCCACCCCACAGAAGCAAGCAAAAGGCTTCTTCAGCTACAGAGCGGACATTTTTGCTGAAAACTTTGTGCCCAACTGGCGTGGGCCAGGGGGCAGcttttttggcatgttctccatctTCTTCCCCTCAGCCACCGGCATTCTCGCAGGGGCCAATATCTCTGGAGACCTGAAGGATCCCAATGTGGCTATCCCCCGGGGCACAATGCTAGCCATTTTCTGGACCACTGTGTCTTATCTCATCATCTCAGCTACTATTGGCTCCTGTGTTATCCGAGATGCCTCTGGTAGCCTTAATGACACATTAATGTCTGGGCCTGGTGCTGAAGACTGCCTGGGATTGGGCTGCAGCTATGGCTGGAACTTTAGTGACTGCATCACCAACAAGACCTGCACTTATGGCCTTAGTAACTATTATCAGacTATGAGCATGGTGTCTGGATTTGCTCCTCTGATTGCAGCTGGTATATTTGGAGCTACTCTGTCCTCAGCACTGGCTTGCCTGGTTTCAGCACCCAAAGTATTTCAGTGCCTGTGCAAAGACAGGTTGTATCCGGTGATTGGCTTTTTTGGGAAGGGCTATGGGAAGAACGATGAGCCATACAGAAGCTACCTCCTAACCTATGTGATTGCTGTTTGCTTCATTCTTATTGCTGAGCTGAACACCATCGCTCCCATCATCTCCAACTTCTTCCTGTGCTCCTACGCCCTCATTAACTTCAGCTGTTTCCATGCCTCCATCACCAACTCTCCTGGCTGGCGTCCCTCTTTCCGCTTCTACAGTAAGTGGGCGTCTTTAGTGGGTGCTGTGGTGTCGGTCATCATCATGTTCCTCCTCACCTGGTGGGCCGCTCTCATAGCCATAGGGATAGTGATCTTTCTGCTGGCATACGTGCTTTACAAGAAACCATctGTAAACTGGGGATCCTCAGTGCAAGCAGGCTCCTATAACATGGCACTGTCCCAGTGTGTGGGTCTCAACCAAGTAGAAGAACACATAAAGAACTACAGACCTCAGTGTCTGGTTCTCACTGGGCCACCCAGTTTGCGGCCAGCTCTGGTGGACTTTGTAGGTACCTTCACCAAAAACCAGAGTTTGATGTTGTGTGGAAACATTGTTGTTGGAGGACCTTCACCTGATGCTGTGGATGCTGCCAACAGTAGCAGTCATGTGGCGTGGCTCAACAAGAGAGGCATCAAGTCTTTCTATCATGGAGTGGTTGCTGATGATCTGCGCACTGGAACCCAGATGTTGCTGCAGGGTGCAGGTTTAGGTCGGATCCGGCCTAACGTCTTAATGTTGGGATTTAAGAAGAACTGGACCAAGTGTCCACCAACCAGCATAGAAAATTATATTGGAATTTTACATGATGCATTTGACCTACAGTATGGAGTGTGCATTCTGCGGATGAAGGACGTTCTTGATTTGTCTTATCAAATGCAAGCACATGTTAACCCAGGGTTTGATCCAGCTACAGAACCAGGACTAGATGCCAGAAACATCAGCACATCAATGGATCCTGAATCGCTTATAGCCATGACTCAACCCAGCACCGTCTTTCAGACTAAGCAAGAAAAGAAGACTATTGATGTGTATTGGCTGTTTGATGATGGAGGCCTGACGCTACTGCTGCCGTACCTTCTGAAGCGTAAGAAGCGCTGGGGCAGGTGTAAAGTGAGAGTGTTTGTGGGAGGAGAGATTCAACATGCTGAGGAACAGAAACAAGAGCTAACAGCTCTCATCAGCAAGTTTCGCCTTGGATTCCATGAGATTCAAATCCTCCCTGACATCAACGAGAAACCTCAGCCTGAACATGTTAAGAAGTTTGAAGACCTGTTAGGGCCATACAGGGCACATGCTATGCAAAAGAATGGAGAAAGAGGTGCCCAGACCTTCAGTGAGTGTCCGTGGACAGTGTCTGATGAAGATTTTGAAAAGAATTTGGCAAAGTCTTTCAGACAGATCCGCCTTAACGAAGTCCTAAAGGACTACTCGAGAGATGCTGCATTGATTATTGTGACCATGCCCATAGGCCGGAGAGGAGCCTGCCCGAGTGCACTCTACATGGCTTGGCTGGAGACCGTGTGCCGTGACCTGCGACCTCCAGTCCTGCTGGTCAGGGGGAACCAGGAGAATGTCCTCACTTTCTACTGCCAGTGATCAACCTGCCAAAATCTTATTAGCTGCAGCTGTGAAGTGCAGGACAGGAGACTGGTGGTCCCTCTAGAACTATGGTTCATAATCTGGGGATTCTGATGTAGTCCCTTGGAGGAGAGGGATGCTGATTTTAAACCCTAAAAAGGGGTTGCACAGTACAAAAAGGGTATGAATCCCCGTtctagaaaatgtaaaataagatGGTACTCACTCTAGCACTtgaatttgtcttttttaactAATGAACTGTTGCTAAAATGTTTGAGTCATTATAGGACTGATCCAAgtgatgtaatattttatttgattccTATAATTCTGTGCAAAATATTTCTAGAATATGTTATATTATCTGAGAAGTTGAAGGTTTTGTTGTGTTtagtaatataattttataactcAGTTTTTTGACAATAGGGGTGGTCTTTACTGTAAATGTTTAGGTGGTGGACCCACTTTCAATCCAGCATTTACATTAGCATGTGTAAAACTGCCagcatttacttacattttctaCGTACACCGGTTCCTCACACACTAGGATGTCAGTTTTATATCAGATGAATTACTTGCGCAACAGCAGCATTTTAACCATAAACTGACCAGTAATGGAATTTGGATAAGAAAATGTACAGCAACAAATAATGTCCAGCCCATAAACAGTGAACATAGTAAAGTAAAATCAGTAATGTATTCATCAAATGCATTTTGTTAtattaaagtgtattaaaaatttaAGCAATTA

Function


symbol description
slc12a3 Predicted to enable sodium:potassium:chloride symporter activity. Acts upstream of or within cloaca development and pronephric duct morphogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in apical plasma membrane. Is expressed in several structures, including blood; intermediate mesoderm; opercular flap; pleuroperitoneal region; and scale. Human ortholog(s) of this gene implicated in Gitelman syndrome and essential hypertension. Orthologous to human SLC12A3 (solute carrier family 12 member 3).

NR:

description
solute carrier family 12 member 3

GO:

id name namespace
GO:0055085 transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0016021 integral component of membrane cellular_component
GO:0015377 cation molecular_function

KEGG:

id description
K14426 SLC12A3, TSC; solute carrier family 12 (sodium/chloride transporter), member 3

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007249198.3 True 3863 mRNA 0.47 26 15808189 15822339

Neighbor


gene id symbol gene type direction distance location
nup93 nup93,LOC107549634 coding upstream 3613 15777725 ~ 15804576 (+)
c18h16orf70 c4h16orf70,clg19h16orf70,si:dkey-102f14.5,LOC103042166,LOC107686270,LOC106573725,LOC105892482 coding upstream 57727 15737988 ~ 15750462 (+)
kiaa0513 kiaa0513,LOC107740318,LOC107583795 coding upstream 90978 15691503 ~ 15717211 (+)
LOC103043506 LOC108423614 coding upstream 119475 15678723 ~ 15688714 (+)
LOC103031192 LOC108423591,LOC105018602,LOC103466747,LOC108229128 coding upstream 306976 15482444 ~ 15501213 (+)
herpud1 NA coding downstream 1380 15823719 ~ 15833040 (+)
cetp cetp coding downstream 10814 15833153 ~ 15846690 (+)
nlrc5 NA coding downstream 29517 15851856 ~ 15875235 (+)
cpne2 cpne2,LOC107583787,LOC107740309 coding downstream 56559 15878898 ~ 15932466 (+)
rspry1 rspry1,LOC107583786,LOC107672266 coding downstream 125247 15947586 ~ 15959406 (+)
G158627 NA non-coding upstream 656 15807319 ~ 15807533 (+)
G158624 NA non-coding upstream 35749 15772226 ~ 15772440 (+)
G158582 NA non-coding upstream 223195 15583441 ~ 15584994 (+)
G158580 NA non-coding upstream 235851 15571534 ~ 15572338 (+)
G158576 NA non-coding upstream 304145 15503526 ~ 15504044 (+)
G158640 NA non-coding downstream 84814 15907153 ~ 15907900 (+)
G158641 NA non-coding downstream 86664 15909003 ~ 15909291 (+)
G158644 fam192a non-coding downstream 113739 15936078 ~ 15942262 (+)
LOC111194770 NA non-coding downstream 146947 15969286 ~ 15986748 (+)
G158651 NA non-coding downstream 154513 15976852 ~ 15978946 (+)
LOC103041352 NA other upstream 32023 15775424 ~ 15776166 (+)
LOC107197617 NA other upstream 36244 15771295 ~ 15771945 (+)
LOC103041858 NA other upstream 39528 15768055 ~ 15768661 (+)
c18h11orf16 NA other upstream 492637 15306212 ~ 15315552 (+)
LOC111194769 NA other upstream 670919 15128368 ~ 15137270 (+)
G158779 NA other downstream 556920 16379259 ~ 16379823 (+)
siah1 siah1,LOC107549647,LOC107742888,LOC106573709 other downstream 720539 16542878 ~ 16571458 (+)
st3gal2 st3gal2,LOC107686287,LOC106573711 other downstream 831797 16654136 ~ 16725209 (+)
LOC103031606 arih1,LOC108423892,LOC107742882,LOC107672283,LOC107549652,LOC105892496 other downstream 957167 16779506 ~ 16798400 (+)
map2k1 map2k1,LOC107596971,LOC107583767,LOC107686295 other downstream 1279273 17101612 ~ 17172228 (+)

Expression



Co-expression Network