LOC103026424 (ctsd,LOC107686244,LOC107672285,LOC107740314)



Basic Information


Item Value
gene id LOC103026424
gene name ctsd,LOC107686244,LOC107672285,LOC107740314
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035914.1
NCBI id CM008317.1
chromosome length 41377133
location 14546807 ~ 14557263 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007250573.3
ACCATAAGTGACCCAGCAGTCAGCTGATTCGAGTCGTTTAGTTTAGCCCAGATCCCACAGCGGAGAGTCGGCATAAACACCCCGGGAGGAGGCGCGGTGAACCCCAGCTGCTTTTATCGACCTGCTGAAACCGACAAGATGAAGCTGgcctgtctgctgctgctggctgcTGTCGCCTGGAGCTCCGAGGCGATAGTTAGGATTCCCCTGAAGAAGTTTCGCTCCATAAGGCGGTCCATGACTGACTCAGGCAGAGCTATGGAAGAACTCCTAGCTGACTCTCAGTCTACAAAGTACAACCTGGGGTTCCCCCCTCCCAGCAACGGTCCCACCCCTGAAACCCTCAAGAACTATCTGGACgCCCAGTATTATGGAGAAATAGGTCTTGGCACTCCTATCCAGACCTTTACTGTGGTGTTTGACACTGGATCCTCCAACCTATGGGTTCCCTCTGTCCACTGCTCCCTTACTGACATTGCCTGCTTGCTTCATCACAAGTACAATGGAGCTAAATCCAGCACCTATGTGAAGAATGGCACTGCTTTTGCCATCCAGTATGGCAGTGGGAGCTTGTCTGGGTATCTCAGCCAGGACACATGCAcaatcGGTGATATTGCTGTTGAAAAGCAGATATTTGGGGAGGCTATCAAACAGCCTGGAGTTGCTTTCATTGCAGCAAAGTTTGATGGCATCTTGGGTATGGCCTATCCTCGGATCTCTGTGGATGGGGTTCCTCCTGTGTTTGACATGATGATGAGCCAAAAGAAAGTGGAGAAAAACGTCTTCTCTTTCTATTTAAACAGgaACCCAGATACTCAGCCTGGTGGTGAACTCCTGCTGGGTGGGACTGACCCGAAGTACTACACTGGAGACTTCCACTACGTGAATATCAGCAGACAGGCTTACTGGCAGGTTCATATGGACGGCATGAACATCGGCAGCCAGCTGAACCTTTGTAAGGGAGGCTGTGAGGCCATTGTAGACACTGGAACGTCGCTGATCACTGGACCTGCAGCTGAGGTCAAGGCCCTGCAGAAAGCCATCGGAGCTATCCCCCTCATCCAGGGAGAGtatATGGTTGACTGCAAGAAGGTCCCCTCTCTTCCTACTATCTCCTTTGTTTTGGGCGGACAATCCTACACCCTGACTGGAGAACAATACATTCTCAAGGAGAGCCAGGCTGGTAAAGAGATCTGCCTGAGTGGCTTCATGGCTCTGGATATCCCTCCCCCAGCCGGACCACTGTGGATTCTGGGAGACGTGTTCATTGGCCAGTACTACACTGAGTTTGACCGCGAAAACAACAGAGTGGGCTTCGCCAAGGCTGTCTAAAGGCTGTTGAGTGAAATTGCTAAAGGGTCAGAGAGGAGTTTAAATAACTGTAGGAAAGCTTGAAAGAACCCTACACATCATATCAGCTGCTTTTGTAATATCTACATACCTAGCGATATGATAGTGTTGTGTTTTGCACTGTGCTTTCTTAGCTTATACAAATACTCCGTTATCAGTGGGCTTGAGAAGTCTAAACGAATCAGGGAAAGGTACTACAGATATGCTAGGAAAAACAGACGTGTGGTTTTAATACGTTTTAACTTGTTTTAAGGTTTTATGTCtgatttttagttcatttaaatcTGCTTTTTTGAAAATACCTCTGATTTTAATGTGTACAATTGAATTGgatgaaataaatgttttaaaacttgtGTTCATAACCTGTAATCACTTTTTTCCACCCAGCCCActtgtgtaatacattttttcagggcttttgtttgtttttttttgttgttgtgggTTATGGGCAATGCTTTCTGTTTGGCTGATGTGCATGAGAATGTTCAGAACTCTGGCACTACACTAACAATTGATTTTAATCAAGGTTAAAATTCTCATCCTGACTGATAAACAAACAGCGATGTACCAATATACAAcaattaaaacacacaatacagtaa

Function


symbol description
ctsd Predicted to enable aspartic-type endopeptidase activity. Acts upstream of or within muscle structure development; response to bacterium; and retinal pigment epithelium development. Predicted to be active in lysosome. Is expressed in several structures, including eye; liver; muscle; pleuroperitoneal region; and unfertilized egg. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; and neuronal ceroid lipofuscinosis 10. Orthologous to human CTSD (cathepsin D).

NR:

description
cathepsin D

GO:

id name namespace
GO:0003406 retinal pigment epithelium development biological_process
GO:0009617 response to bacterium biological_process
GO:0006508 proteolysis biological_process
GO:0004190 aspartic-type endopeptidase activity molecular_function

KEGG:

id description
K01379 CTSD; cathepsin D

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007250573.3 True 1958 mRNA 0.46 9 14546807 14557263

Neighbor


gene id symbol gene type direction distance location
bhlhe41 bhlhe41 coding upstream 7443 14533728 ~ 14539364 (+)
LOC103025600 itpr2 coding upstream 32661 14405581 ~ 14514146 (+)
eea1 eea1 coding upstream 172004 14343739 ~ 14374803 (+)
nudt4 nudt4,LOC107553971,LOC107740279,LOC107672310,LOC107686239,LOC105898052 coding upstream 204487 14323212 ~ 14342320 (+)
ube2n ube2na,ube2nb,ube2n,LOC105897570,LOC107707098,LOC107658971,LOC106609528 coding upstream 224949 14308368 ~ 14321858 (+)
lrriq1 NA coding downstream 31195 14588458 ~ 14632192 (+)
alx1 alx1 coding downstream 79529 14636792 ~ 14643499 (+)
nts nts coding downstream 174529 14731792 ~ 14737727 (+)
LOC103031823 LOC108263962,LOC107740339,LOC107583811 coding downstream 260805 14818068 ~ 14830344 (+)
LOC103031502 eif4g2b,LOC108431851,LOC107730533,LOC107569652,LOC103379577 coding downstream 550100 15107363 ~ 15120305 (+)
G158093 ppfibp1 non-coding upstream 356765 14168959 ~ 14190042 (+)
G158086 endouc,LOC108425714,LOC107749311,LOC107686338,LOC107672228 non-coding upstream 389774 14151418 ~ 14157033 (+)
G158085 NA non-coding upstream 396318 14149486 ~ 14150489 (+)
G158068 NA non-coding upstream 429964 14116319 ~ 14116843 (+)
G158038 ric8b non-coding upstream 454275 14088466 ~ 14092532 (+)
G158238 NA non-coding downstream 3387 14560650 ~ 14562131 (+)
G158335 NA non-coding downstream 353695 14910958 ~ 14919932 (+)
G158357 NA non-coding downstream 421480 14978743 ~ 14980092 (+)
G158359 NA non-coding downstream 450242 15007505 ~ 15008083 (+)
G158381 NA non-coding downstream 512523 15069786 ~ 15070409 (+)
LOC103042073 LOC103042073,LOC108418727 other upstream 566782 13973821 ~ 13980025 (+)
LOC107197649 LOC108416831 other upstream 804307 13733945 ~ 13742500 (+)
hsbp1 hsbp1,hsbp1b,LOC107583924,LOC107553992,LOC107670150,LOC107749299 other upstream 1805805 12735519 ~ 12741002 (+)
LOC103031933 ttc38,LOC103031933,LOC108414465,LOC104940279,LOC106573176,LOC100694777,LOC107722483,LOC107673144 other upstream 2180037 12340006 ~ 12366770 (+)
hipk2 hipk2,LOC107722467 other upstream 3403336 11031065 ~ 11143471 (+)
G158369 NA other downstream 492959 15050222 ~ 15050718 (+)
LOC111194769 NA other downstream 571105 15128368 ~ 15137270 (+)
c18h11orf16 NA other downstream 748949 15306212 ~ 15315552 (+)
LOC103041858 NA other downstream 1210792 15768055 ~ 15768661 (+)
LOC107197617 NA other downstream 1214032 15771295 ~ 15771945 (+)

Expression



Co-expression Network