agk (agk)



Basic Information


Item Value
gene id agk
gene name agk
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035914.1
NCBI id CM008317.1
chromosome length 41377133
location 18004007 ~ 18010554 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007255970.2
TTTGGTGTAACACCAGTGGGTCACGCTGGTAGAGTAATGTCAGGGGCTGAATGAGAGAATCAGGCTCTCAGAGCTCAGGGATCGTACTGTTTGTTCCGCGGGGTTTCACTCTGCTCTGTGCGCTCGGTGTCAGTGTGGTGTAGCCGGTGGTGAGCGCTGGGACCATGGGCCGGGTGGTGAAGGTGTTGAGGACTCTAAGGAATCACTGGAAGAAGTCGAGCTTCGCTGCCTGTGTGCTGTCTTACGGCGGATACTGGATTTATGGGAAGCACTGtgaCAGTGTGCTGCGAAGAGAGGCCTGCCAAGAAGCCAGGGAATTTGGCCGGGCATTAATTGGACCACAGGAGCCTTTAAAGAGAGCAACAGTAATCCTGAATCCTGCAGCAAGCAATGGAAAAGCCAACAGTCTGTTTGAGAAGAATGCAGCCCCCATCTTGCACCTTGCTGGAGTGGAGATCAAAATTGTGAAGACTGACTATGAAGGGCAGGCGAAAAAGCTAATGGATTTCATGGAACAGACAGACATGCTAATTGTTGCTGGGGGGGATGGGACTCTGCAGGAGgtGGTAACTGGTTTACTACGAAGAAATGATGAGGAAGCGTTTAGTAAAACGCCCATAGGCTTCATTCCTCTGGGCGCTCACAATTCCTTATGCCAAAGTCTACACCTAGCTACTGACAACACAGTCAGGCGCATCACTTCCGCTACGCTGTCCATTCTCAAAGGCGAGACAGTACCGCTGGACATCTTACAGATAAAGAGTGAAAAGGAGCAACCAGTCTTTGCTGTCATGAGTATACGCTGGGGTTCCTTCAGAGATGTTGCAGAATCCATCAGCAAATATTGGTACCTTGGTCCCTTGAAAACAAGAGCAGCGCATTGGTTCAGTACATTAAAGGAATGGCCACAGACTCGCCAAGCTTCGCTATCGTATCTGCCTCCTGTTCCTCGGCCTCCGGAGATGCCCACTGAAAAGCCCCAAAGACCCAACCTGCTACACCGCATCTATATCAGGCTTCAGAATTATTGGAATCCTCCTGTGGAAGAGCCCCCTGTAGAGCCAGAGCCAGAAATTTGGGAGGAGAAGCATCTCTCCACCTTGGAGCTCACAATAAGCACACAGAACAAAAACCCTGTGAAGAACCGTACAGATGATTCTATGGTGCTTTCAGTGGAACCAGACACACTCACAGTTGGACAGTTCATAACTGAAGGTATTAAAAAAGCTGAGAATCCACTGGAGAGCACAGAACACACACTTCAGATAGAGGCCAGTGCATGTCGTGTCAATTTGCCTGAGGAGGGCGCTGGCTTTTATAACATTGACAACGAGGCCTTTGAGGCCATGCCAGTGGAAGTGAGGCTACTGCCGCGGAAACTAAGGTTCTTTTGCAGTGCTGAGCGCAGAGAGGAACTGGCACAAGGGAACTGAAGGTggtctggggaaaaaaaatcatacttgTGGAAGGAATCAGTGGAAATCTGAACTTTGGGTTATCGGACTCCTAACAATGGGCTGTGTACTTTCACTGCAGAGATGATGTTAATCATACAGCATCAGAACAGTATTATAACTCGCATCCATCTTACACTTCATTTAGAATTCTTACAAATACTGGCTctggtctcttttttctctaaaaCAGTGCCACTTAATGGCAAGGATTACACAAGCTACTGAGaacattttgataaaaaaataaaaaatcacccATTCTGCTGTACTGGACGTAGTGCTGGTGACTAGGAAGGCCACATGCTGAACTAACGATTAAAAGATGGGTAAAAGGTGGCCACATGAAGAGAAGAACAAATACTCAAATAGGGTGTAAAATTAAAGTGATGATTAATTAGTAGTCCCCAGCCCAAAGTAAACACTGAGCCCACTGCAgcttcagctttctgttcttgactGACAGAAATTAAAACCTGGTTTGGTCTTCTGCTGTTGTAGCCCATCCATCTCAAGGTTTGAGGTGTTGTACATTGTGACATTCTTTTCTGTTTACTGTAGTTTTTGTTTACTCAAAATGGTTTGAACAGTTTCTGTCGACTTCAATAGTAAATCAATGTACCTTTTTTGGCACAGTTCCCCAAACCACCACTTATAGgagattttctcttttattatactaTTCTGAATTTTATAGGCTGTCCCAGGAGATCACCACTTCAGCATTGCAGAAGAAATACTCAAAGTAGCCCATTTGGAATAAAATCATGCTCTGCTCAAAA
>XM_015607532.2
TTTGGTGTAACACCAGTGGGTCACGCTGGTAGAGTAATGTCAGGGGCTGAATGAGAGAATCAGGCTCTCAGAGCTCAGGGATCGTACTGTTTGTTCCGCGGGGTTTCACTCTGCTCTGTGCGCTCGGTGTCAGTGTGGTGTAGCCGGTGGTGAGCGCTGGGACCATGGGCCGGGTGGTGAAGGTGTTGAGGACTCTAAGGAATCACTGGAAGAAGTCGAGCTTCGCTGCCTGTGTGCTGTCTTACGGCGGATACTGGATTTATGGGAAGCACTGtgaCAGTGTGCTGCGAAGAGAGGCCTGCCAAGAAGCCAGGGAATTTGGCCGGGCATTAATTGGACCACAGGAGCCTTTAAAGAGAGCAACAGTAATCCTGAATCCTGCAGCAAGCAATGGAAAAGCCAACAGTCTGTTTGAGAAGAATGCAGCCCCCATCTTGCACCTTGCTGGAGTGGAGATCAAAATTGTGAAGgtGGTAACTGGTTTACTACGAAGAAATGATGAGGAAGCGTTTAGTAAAACGCCCATAGGCTTCATTCCTCTGGGCGCTCACAATTCCTTATGCCAAAGTCTACACCTAGCTACTGACAACACAGTCAGGCGCATCACTTCCGCTACGCTGTCCATTCTCAAAGGCGAGACAGTACCGCTGGACATCTTACAGATAAAGAGTGAAAAGGAGCAACCAGTCTTTGCTGTCATGAGTATACGCTGGGGTTCCTTCAGAGATGTTGCAGAATCCATCAGCAAATATTGGTACCTTGGTCCCTTGAAAACAAGAGCAGCGCATTGGTTCAGTACATTAAAGGAATGGCCACAGACTCGCCAAGCTTCGCTATCGTATCTGCCTCCTGTTCCTCGGCCTCCGGAGATGCCCACTGAAAAGCCCCAAAGACCCAACCTGCTACACCGCATCTATATCAGGCTTCAGAATTATTGGAATCCTCCTGTGGAAGAGCCCCCTGTAGAGCCAGAGCCAGAAATTTGGGAGGAGAAGCATCTCTCCACCTTGGAGCTCACAATAAGCACACAGAACAAAAACCCTGTGAAGAACCGTACAGATGATTCTATGGTGCTTTCAGTGGAACCAGACACACTCACAGTTGGACAGTTCATAACTGAAGGTATTAAAAAAGCTGAGAATCCACTGGAGAGCACAGAACACACACTTCAGATAGAGGCCAGTGCATGTCGTGTCAATTTGCCTGAGGAGGGCGCTGGCTTTTATAACATTGACAACGAGGCCTTTGAGGCCATGCCAGTGGAAGTGAGGCTACTGCCGCGGAAACTAAGGTTCTTTTGCAGTGCTGAGCGCAGAGAGGAACTGGCACAAGGGAACTGAAGGTggtctggggaaaaaaaatcatacttgTGGAAGGAATCAGTGGAAATCTGAACTTTGGGTTATCGGACTCCTAACAATGGGCTGTGTACTTTCACTGCAGAGATGATGTTAATCATACAGCATCAGAACAGTATTATAACTCGCATCCATCTTACACTTCATTTAGAATTCTTACAAATACTGGCTctggtctcttttttctctaaaaCAGTGCCACTTAATGGCAAGGATTACACAAGCTACTGAGaacattttgataaaaaaataaaaaatcacccATTCTGCTGTACTGGACGTAGTGCTGGTGACTAGGAAGGCCACATGCTGAACTAACGATTAAAAGATGGGTAAAAGGTGGCCACATGAAGAGAAGAACAAATACTCAAATAGGGTGTAAAATTAAAGTGATGATTAATTAGTAGTCCCCAGCCCAAAGTAAACACTGAGCCCACTGCAgcttcagctttctgttcttgactGACAGAAATTAAAACCTGGTTTGGTCTTCTGCTGTTGTAGCCCATCCATCTCAAGGTTTGAGGTGTTGTACATTGTGACATTCTTTTCTGTTTACTGTAGTTTTTGTTTACTCAAAATGGTTTGAACAGTTTCTGTCGACTTCAATAGTAAATCAATGTACCTTTTTTGGCACAGTTCCCCAAACCACCACTTATAGgagattttctcttttattatactaTTCTGAATTTTATAGGCTGTCCCAGGAGATCACCACTTCAGCATTGCAGAAGAAATACTCAAAGTAGCCCATTTGGAATAAAATCATGCTCTGCTCAAAA

Function


symbol description
agk Predicted to enable acylglycerol kinase activity; ceramide kinase activity; and diacylglycerol kinase activity. Predicted to be involved in ceramide biosynthetic process; phosphorylation; and protein insertion into mitochondrial inner membrane. Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Predicted to be integral component of mitochondrial inner membrane. Predicted to be part of TIM22 mitochondrial import inner membrane insertion complex. Predicted to be active in membrane and mitochondrion. Human ortholog(s) of this gene implicated in Sengers syndrome and cataract 38. Orthologous to human AGK (acylglycerol kinase).

NR:

description
acylglycerol kinase, mitochondrial-like

GO:

id name namespace
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway biological_process
GO:0016310 phosphorylation biological_process
GO:0046486 glycerolipid metabolic process biological_process
GO:0031966 mitochondrial membrane cellular_component
GO:0047620 acylglycerol kinase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0003951 NAD+ kinase activity molecular_function
GO:0004143 diacylglycerol kinase activity molecular_function

KEGG:

id description
K09881 AGK; acylglycerol kinase

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007255970.2 True 2236 mRNA 0.46 15 18004007 18010554
XM_015607532.2 False 2143 mRNA 0.46 14 18004007 18010554

Neighbor


gene id symbol gene type direction distance location
LOC103029004 NA coding upstream 9637 17985993 ~ 17994370 (+)
kbtbd4 kbtbd4,LOC107708223,LOC107738697,LOC107596956,LOC107672308 coding upstream 35071 17964383 ~ 17968936 (+)
ddb2 ddb2 coding upstream 45573 17949130 ~ 17958434 (+)
LOC103039437 tle3a,LOC108424090,LOC107596960,LOC107672253,LOC108264729 coding upstream 206259 17763691 ~ 17797748 (+)
LOC103024336 NA coding upstream 358758 17625054 ~ 17645249 (+)
wee2 wee2 coding downstream 13350 18023904 ~ 18030005 (+)
LOC107197792 LOC107197792 coding downstream 19934 18030488 ~ 18035696 (+)
cftr cftr,LOC107738689,LOC107583749,LOC107596947,LOC107708216 coding downstream 124163 18134717 ~ 18164724 (+)
LOC103028633 NA coding downstream 250611 18261165 ~ 18265803 (+)
arpin arpin coding downstream 404973 18415527 ~ 18435115 (+)
G159129 NA non-coding upstream 7279 17995698 ~ 17996728 (+)
G159122 NA non-coding upstream 57324 17942316 ~ 17946683 (+)
G159120 kif23,LOC107686310 non-coding upstream 65919 17926988 ~ 17938088 (+)
G159115 NA non-coding upstream 133539 17870007 ~ 17870468 (+)
G159028 NA non-coding upstream 404653 17596059 ~ 17599354 (+)
G159182 NA non-coding downstream 97609 18108163 ~ 18109539 (+)
G159184 asz1 non-coding downstream 103451 18114005 ~ 18128429 (+)
G159272 NA non-coding downstream 400758 18411312 ~ 18411936 (+)
LOC111194744 NA non-coding downstream 402807 18413361 ~ 18413950 (+)
G159274 NA non-coding downstream 417601 18428155 ~ 18428426 (+)
rapsn rapsn other upstream 18103 17971096 ~ 17985904 (+)
smad6 smad6,smad6b,LOC107583766,LOC107672304,LOC107596967,LOC107738716,LOC107686299 other upstream 631801 17327100 ~ 17372206 (+)
zwilch zwilch other upstream 814756 17177675 ~ 17189251 (+)
map2k1 map2k1,LOC107596971,LOC107583767,LOC107686295 other upstream 831779 17101612 ~ 17172228 (+)
LOC103031606 arih1,LOC108423892,LOC107742882,LOC107672283,LOC107549652,LOC105892496 other upstream 1205607 16779506 ~ 16798400 (+)
necab2 necab2,LOC107694920,LOC107672281,LOC106573751 other downstream 514974 18525528 ~ 18576437 (+)
G159666 NA other downstream 2174962 20185516 ~ 20186919 (+)
G159728 NA other downstream 2726044 20736598 ~ 20737049 (+)
G159748 chd2,LOC107715217,LOC107601632,LOC107549011,LOC107715589,LOC107690375 other downstream 2998748 21009302 ~ 21011794 (+)
fam174b NA other downstream 3050102 21060656 ~ 21074573 (+)

Expression



Co-expression Network