ddb2 (ddb2)



Basic Information


Item Value
gene id ddb2
gene name ddb2
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035914.1
NCBI id CM008317.1
chromosome length 41377133
location 17949130 ~ 17958434 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007255975.3
cactcaagcgTTACAAAACAATCCGCGGGTTACGTCACGCCCACACACGTGTGACCCTCTTCGCGCTGTTTATACTCTTTAAGGTCAGTGGAAGAAATAAACGGAGTGTATCGATATAAACAGCGCGTGGGGCTTTCTGTACTGCTGAAAACACGTCTGAAAGACAGAAAACTGCTGTACAATGGCGAGAGGGAAGAGGAAAGAGGAGGGCGCGAGAAAACGACAGAATGCTGAGGTTTCTGAAACGCTTTCCAAAAAGCTGAAAGCAAAGAAAGATGGACGGGCTGGATCAAACACAGTGTACATTCAGGCAAGTGTAAAGTGGACTGGAGGACTGAAGAAATGCAGCCAGATAAGCATACCTCATTACATCTACAAGAGCTCCTTAGGACAGAGCATCCACTCTCAACTACGACAGTGTCTCCAAGAGCCTTTTATTCGCTCCCTGGAATCATTCAGACTGCACCGAACAGCCAGCCCTTTTGAACGGAGGGTCACATGTCTGGAGTGGCATCCCAGTCATCCCAGCACTGTGGCAGTGGGCTCTAAGGGTGGAGACATCATGTTGTGGGACTATGAAATTTTGAACAAGAAATCCTTCATACAAGGGAAAGGAGCTGGTGACTTTATTGGGGGCATGAAGTTCTGCCCCACAGACATATCCAAAGTCTATGCTGCCGCTGGTGATGGCACTGTGACTTTGCAGAGCTTTGAGGGTCTCCCAAGCGAGACACTATCTCGAACCCCAGACTGCGGCCATGATCACCACTCTCTTTGCTACTGGTACTGCTGTCTGGATGTGTCCGTTAGCCGCCAAATGCTTGTAACTGGAGACAATGCAGGATCCCTTCTTTTGATTGGTTTGGATGGAACAAAGATTTTCAGTGAAAAGCTGCACAAAGCCAAAGTGACGCATGCAGAATTCAACCCTCGATGTGACTGGCTAGTGGCAACATCGTCTGTAGACAACACTGTCAAGCTGTGGGATCTCAGGAACATGAAGGATAAAAGCAGTTACCtgcatgaaatgaaacatgagAAACCAGTAAATGCTGcCTATTTCAACCCCACGGACTGCACCAAGCTCCTCACCACAGACCAAATGAATGAGATCAGGATTTATTCCTCAAGTGATTGGTCTAAGCCAGCTCAGGTTATTGTGCATCCACATCGCCAGTTCCAGCATCTGACCCCAAtcaagGCAACCTGGCATCCCATATATGACCTCATTGTGGCTGGCCGTTATCCTGATGACCGTGTGTTTGTTGGTGATGAGAGAACTATTGATATCTTTGATGCTAACACTGGCAAACTCCTTTATAAGCTGAAAGACCCCAACACCAATGGAATTGTATCTctcAATAAATTTAACCCATTGGGGGATGTGTTGGCATCTGGAATGGGCTATAATATTTTGATATGGAACCGAGACGATACTGTGAGCCAGAGTCCGTGTAGGAGACAGAGGGAGGAAGGATCAGAGCCAGGAGGGAGAGCTGGAAGCTCCAGAGGCCAGCGAGGCAATCCACAGCGGCCCCGCGGTGACAGACGTGGAACTGCAGACAGTGCCAAGGTGAAGAAAAAACTGGCATCACTGGAATCAACTGAGACCAATTCAAAAACCAGAAGCAAGACTGAAAGTAAAATGCTGAAAAACAAGAAGTCCTAGTTGACCAAAGCTAATCTAGGCACATTTTTACTGTAAAGCAGTTATACAAACCAGTTCCTGTTTATATAGcaaatttattttcttataaaaAAGAGCTGAATTGTTTTTCAAAGTAAAACAGGTTGTTCCAGTTTGTATTGTATGTTGTAAACTCAGAACTTATTAAACATTTGTACTTTTTCACATAAAAATAA
>XM_007255976.3
gcgTTACAAAACAATCCGCGGGTTACGTCACGCCCACACACGTGTGACCCTCTTCGCGCTGTTTATACTCTTTAAGGTCAGTGGAAGAAATAAACGGAGTGTATCGATATAAACAGCGCGTGGGGCTTTCTGTACTGCTGAAAACACGTCTGAAAGAAAACTGCTGTACAATGGCGAGAGGGAAGAGGAAAGAGGAGGGCGCGAGAAAACGACAGAATGCTGAGGTTTCTGAAACGCTTTCCAAAAAGCTGAAAGCAAAGAAAGATGGACGGGCTGGATCAAACACAGTGTACATTCAGGCAAGTGTAAAGTGGACTGGAGGACTGAAGAAATGCAGCCAGATAAGCATACCTCATTACATCTACAAGAGCTCCTTAGGACAGAGCATCCACTCTCAACTACGACAGTGTCTCCAAGAGCCTTTTATTCGCTCCCTGGAATCATTCAGACTGCACCGAACAGCCAGCCCTTTTGAACGGAGGGTCACATGTCTGGAGTGGCATCCCAGTCATCCCAGCACTGTGGCAGTGGGCTCTAAGGGTGGAGACATCATGTTGTGGGACTATGAAATTTTGAACAAGAAATCCTTCATACAAGGGAAAGGAGCTGGTGACTTTATTGGGGGCATGAAGTTCTGCCCCACAGACATATCCAAAGTCTATGCTGCCGCTGGTGATGGCACTGTGACTTTGCAGAGCTTTGAGGGTCTCCCAAGCGAGACACTATCTCGAACCCCAGACTGCGGCCATGATCACCACTCTCTTTGCTACTGGTACTGCTGTCTGGATGTGTCCGTTAGCCGCCAAATGCTTGTAACTGGAGACAATGCAGGATCCCTTCTTTTGATTGGTTTGGATGGAACAAAGATTTTCAGTGAAAAGCTGCACAAAGCCAAAGTGACGCATGCAGAATTCAACCCTCGATGTGACTGGCTAGTGGCAACATCGTCTGTAGACAACACTGTCAAGCTGTGGGATCTCAGGAACATGAAGGATAAAAGCAGTTACCtgcatgaaatgaaacatgagAAACCAGTAAATGCTGcCTATTTCAACCCCACGGACTGCACCAAGCTCCTCACCACAGACCAAATGAATGAGATCAGGATTTATTCCTCAAGTGATTGGTCTAAGCCAGCTCAGGTTATTGTGCATCCACATCGCCAGTTCCAGCATCTGACCCCAAtcaagGCAACCTGGCATCCCATATATGACCTCATTGTGGCTGGCCGTTATCCTGATGACCGTGTGTTTGTTGGTGATGAGAGAACTATTGATATCTTTGATGCTAACACTGGCAAACTCCTTTATAAGCTGAAAGACCCCAACACCAATGGAATTGTATCTctcAATAAATTTAACCCATTGGGGGATGTGTTGGCATCTGGAATGGGCTATAATATTTTGATATGGAACCGAGACGATACTGTGAGCCAGAGTCCGTGTAGGAGACAGAGGGAGGAAGGATCAGAGCCAGGAGGGAGAGCTGGAAGCTCCAGAGGCCAGCGAGGCAATCCACAGCGGCCCCGCGGTGACAGACGTGGAACTGCAGACAGTGCCAAGGTGAAGAAAAAACTGGCATCACTGGAATCAACTGAGACCAATTCAAAAACCAGAAGCAAGACTGAAAGTAAAATGCTGAAAAACAAGAAGTCCTAGTTGACCAAAGCTAATCTAGGCACATTTTTACTGTAAAGCAGTTATACAAACCAGTTCCTGTTTATATAGcaaatttattttcttataaaaAAGAGCTGAATTGTTTTTCAAAGTAAAACAGGTTGTTCCAGTTTGTATTGTATGTTGTAAACTCAGAACTTATTAAACATTTGTACTTTTTCACATAAAAATAA
>XM_007255977.3
cactcaagcgTTACAAAACAATCCGCGGGTTACGTCACGCCCACACACGTGTGACCCTCTTCGCGCTGTTTATACTCTTTAAGGTCAGTGGAAGAAATAAACGGAGTGTATCGATATAAACAGCGCGTGGGGCTTTCTGTACTGCTGAAAACACGTCTGAAAGACAGAAAACTGCTGTACAATGGCGAGAGGGAAGAGGAAAGAGGAGGGCGCGAGAAAACGACAGAATGCTGAGGTTTCTGAAACGCTTTCCAAAAAGCTGAAAGCAAAGAAAGATGGACGGGCTGGATCAAACACAGTGTACATTCAGGCAAGTGTAAAGTGGACTGGAGGACTGAAGAAATGCAGCCAGATAAGCATACCTCATTACATCTACAAGAGCTCCTTAGGACAGAGCATCCACTCTCAACTACGACAGTGTCTCCAAGAGCCTTTTATTCGCTCCCTGGAATCATTCAGACTGCACCGAACAGCCAGCCCTTTTGAACGGAGGGTCACATGTCTGGAGTGGCATCCCAGTCATCCCAGCACTGTGGCAGTGGGCTCTAAGGGTGGAGACATCATGTTGTGGGACTATGAAATTTTGAACAAGAAATCCTTCATACAAGGGATGGGTGCAGGAGACTCAATAACAGACATGAAGTTCAACCAGTTCAATACCAATCAGCTCTTCACCTCATCAATTGGGGGTACCACATCCCTTCAGGATTTCAATGGATCAATTATCCAAGTCTTTGCCCAGACAAACTCCTGGGACTACTGGTACTGCTGTCTGGATGTGTCCGTTAGCCGCCAAATGCTTGTAACTGGAGACAATGCAGGATCCCTTCTTTTGATTGGTTTGGATGGAACAAAGATTTTCAGTGAAAAGCTGCACAAAGCCAAAGTGACGCATGCAGAATTCAACCCTCGATGTGACTGGCTAGTGGCAACATCGTCTGTAGACAACACTGTCAAGCTGTGGGATCTCAGGAACATGAAGGATAAAAGCAGTTACCtgcatgaaatgaaacatgagAAACCAGTAAATGCTGcCTATTTCAACCCCACGGACTGCACCAAGCTCCTCACCACAGACCAAATGAATGAGATCAGGATTTATTCCTCAAGTGATTGGTCTAAGCCAGCTCAGGTTATTGTGCATCCACATCGCCAGTTCCAGCATCTGACCCCAAtcaagGCAACCTGGCATCCCATATATGACCTCATTGTGGCTGGCCGTTATCCTGATGACCGTGTGTTTGTTGGTGATGAGAGAACTATTGATATCTTTGATGCTAACACTGGCAAACTCCTTTATAAGCTGAAAGACCCCAACACCAATGGAATTGTATCTctcAATAAATTTAACCCATTGGGGGATGTGTTGGCATCTGGAATGGGCTATAATATTTTGATATGGAACCGAGACGATACTGTGAGCCAGAGTCCGTGTAGGAGACAGAGGGAGGAAGGATCAGAGCCAGGAGGGAGAGCTGGAAGCTCCAGAGGCCAGCGAGGCAATCCACAGCGGCCCCGCGGTGACAGACGTGGAACTGCAGACAGTGCCAAGGTGAAGAAAAAACTGGCATCACTGGAATCAACTGAGACCAATTCAAAAACCAGAAGCAAGACTGAAAGTAAAATGCTGAAAAACAAGAAGTCCTAGTTGACCAAAGCTAATCTAGGCACATTTTTACTGTAAAGCAGTTATACAAACCAGTTCCTGTTTATATAGcaaatttattttcttataaaaAAGAGCTGAATTGTTTTTCAAAGTAAAACAGGTTGTTCCAGTTTGTATTGTATGTTGTAAACTCAGAACTTATTAAACATTTGTACTTTTTCACATAAAAATAA

Function


symbol description
ddb2 Predicted to enable DNA binding activity. Predicted to contribute to damaged DNA binding activity. Predicted to be involved in DNA repair and response to UV. Predicted to act upstream of or within cellular response to DNA damage stimulus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in nucleus. Is expressed in central nervous system and neurons. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group E. Orthologous to human DDB2 (damage specific DNA binding protein 2).

NR:

description
PREDICTED: DNA damage-binding protein 2

GO:

id name namespace
GO:0016567 protein ubiquitination biological_process
GO:0006281 DNA repair biological_process
GO:0005634 nucleus cellular_component
GO:0003677 DNA binding molecular_function

KEGG:

id description
K10140 DDB2; DNA damage-binding protein 2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007255975.3 True 1863 mRNA 0.46 11 17949130 17958434
XM_007255976.3 False 1852 mRNA 0.46 11 17949137 17958434
XM_007255977.3 False 1842 mRNA 0.45 11 17949130 17958434

Neighbor


gene id symbol gene type direction distance location
LOC103039437 tle3a,LOC108424090,LOC107596960,LOC107672253,LOC108264729 coding upstream 151382 17763691 ~ 17797748 (+)
LOC103024336 NA coding upstream 303881 17625054 ~ 17645249 (+)
morf4l1 morf4l1,LOC107596963,LOC107686360,LOC107738770,LOC107708218,LOC107672187 coding upstream 327002 17610877 ~ 17622128 (+)
LOC103025173 pias1b,LOC108424062,LOC108264782,LOC107596961,LOC107738708 coding upstream 344581 17577392 ~ 17604549 (+)
LOC103029280 skor1 coding upstream 377213 17563875 ~ 17571917 (+)
kbtbd4 kbtbd4,LOC107708223,LOC107738697,LOC107596956,LOC107672308 coding downstream 5949 17964383 ~ 17968936 (+)
LOC103029004 NA coding downstream 27559 17985993 ~ 17994370 (+)
agk agk coding downstream 45573 18004007 ~ 18010554 (+)
wee2 wee2 coding downstream 65470 18023904 ~ 18030005 (+)
LOC107197792 LOC107197792 coding downstream 72054 18030488 ~ 18035696 (+)
G159122 NA non-coding upstream 2447 17942316 ~ 17946683 (+)
G159120 kif23,LOC107686310 non-coding upstream 11042 17926988 ~ 17938088 (+)
G159115 NA non-coding upstream 78662 17870007 ~ 17870468 (+)
G159028 NA non-coding upstream 349776 17596059 ~ 17599354 (+)
G159017 aagab non-coding upstream 492153 17455315 ~ 17456977 (+)
G159129 NA non-coding downstream 37264 17995698 ~ 17996728 (+)
G159182 NA non-coding downstream 149729 18108163 ~ 18109539 (+)
G159184 asz1 non-coding downstream 155571 18114005 ~ 18128429 (+)
G159272 NA non-coding downstream 452878 18411312 ~ 18411936 (+)
LOC111194744 NA non-coding downstream 454927 18413361 ~ 18413950 (+)
smad6 smad6,smad6b,LOC107583766,LOC107672304,LOC107596967,LOC107738716,LOC107686299 other upstream 576924 17327100 ~ 17372206 (+)
zwilch zwilch other upstream 759879 17177675 ~ 17189251 (+)
map2k1 map2k1,LOC107596971,LOC107583767,LOC107686295 other upstream 776902 17101612 ~ 17172228 (+)
LOC103031606 arih1,LOC108423892,LOC107742882,LOC107672283,LOC107549652,LOC105892496 other upstream 1150730 16779506 ~ 16798400 (+)
st3gal2 st3gal2,LOC107686287,LOC106573711 other upstream 1223921 16654136 ~ 16725209 (+)
rapsn rapsn other downstream 12662 17971096 ~ 17985904 (+)
necab2 necab2,LOC107694920,LOC107672281,LOC106573751 other downstream 567094 18525528 ~ 18576437 (+)
G159666 NA other downstream 2227082 20185516 ~ 20186919 (+)
G159728 NA other downstream 2778164 20736598 ~ 20737049 (+)
G159748 chd2,LOC107715217,LOC107601632,LOC107549011,LOC107715589,LOC107690375 other downstream 3050868 21009302 ~ 21011794 (+)

Expression



Co-expression Network