CI01000012_13619458_13633023 (GDH1, GLUD1B, GLUD1A, GDH2, GDH3.2, GLUD1, GDH03, GDH01, GLUD1.S)
Chromosome Information
Item |
Value |
chromosome id |
CI01000012 |
NCBI id |
null
|
chromosome length |
13770000 |
location |
13619009 ~ 13633801 (+) |
genome version |
v1_2015/06_NatureGenetics_grasscarp_Genome |
Sequence
>CI01000012_13619458_13633023.mRNA
ATATATATTAGCCTACATATTAAAAAAAAAAACATTTTCCCCCACAAATATATATTAATTTTTATTTTATTTTTTGAGTGAGATTATTATTATTATTATAGATTATATACATATGTATACGTTTAGGCAACACATTTGGACAGCAGCAACTTTAATACTTTTAACATATTTTTTGTAATACTTTTGCCCTAGGTTGCAAACACTTCAAAGCATGTTTGCTTATGGTTCCTGCTCTCTGAGCGCCTCCCAGCTTGAGGTGGAGACCCACGGCACGCCTGTCTGACTGTTAAAACAACTCGCCAACAGTATTCAAGCCGACACTTTATTTAGTGTAGCAGAAAAGGAGCCGTCGTGGTGTCCGTTTATTCACCCTGACCCACTCTTTGACACTGTCTGTCTTAGTTTTTTCCCTTTATAGATATTGTTAGTTAGTGTGTTAGTTCAAAGTCATGTATAGGTATTTGGGGGAGCTCGTCACACGCGCAGCCGCCAGCAGCTCGCTGGCCTCGGGATGCGTCGATTCCGCTCTGCCCGCTTCGGCGACTCTAATGCGGGTCCGCCGTTACAGCGAAGCCGTAGGAGAAAAAGACGATGACCCTAACTTCTTTAGGATGGTCGAGGGTTTCTTCGACCGCGGAGCTTCTATCGTGGAGGACAAACTCGTGCACGATCTCAAGACAAGAGAAACGCCTGAGCAGAAGAGGCACCGAGTCCGAGGGATCCTCAAGATCATCAAGCCTTGCAACCATGTCCTGTCCGTGTCATTCCCCATCAAGAGAGACAACGGGGAGTGGGAGATGATCGAGGGCTACAGAGCTCAACACAGCCAGCACAGGACTCCGTGTAAAGGAGGTATCCGTTATAGCACAGAGGTGTCAGTCGATGAGGTGAAAGCCCTTGCCTCACTAATGACATACAAATGTGCAGTTGTAGATGTGCCTTTTGGAGGAGCTAAAGCTGGAGTGAAAATTAACCCAAAGAATTACTCTGACACAGAACTGGAGAAGATCACAAGAAGGTTTACCATTGAATTGGCTAAAAAGGGCTTCATTGGGCCTGGCATTGATGTCCCCGCCCCAGATATGAGCACAGGAGAAAGGGAAATGTCCTGGATTGCTGACACGTATGCTAACACAATGGGCCATCATGATATCAATGCTCATGCCTGTGTTACCGGTAAGCCCATCAGCCAGGGTGGCATCCACGGTCGTATATCTGCCACTGGTCGTGGAGTCTTCCATGGCATTGAAAACTTTGTCAATGAGGCTGCTTATATGAGCCAGCTGGGACTGACTCCTGGGTTTGGAGACAAGACGTTTGTCATTCAGGGTTTTGGTAATGTGGGCCTGCACTCCATGCGTTATCTGCACCGTTACGGAGCAAAGTGTGTGGGCGTAGGAGAGGTGGACGGAAGCATCTGGAACCCTAACGGCATCGATCCCAAAGAGCTGGAAGACTATAAGCTGGCCAATGGCACGATTGTTGGCTTCCCCAAGGCCACCCCATATGAAGGCAGCATTTTGGAAGCTCAGTGTGATATCCTGATCCCTGCTGCAAGTGAAAAACAGCTTACAAAGAAAAACGCCAACAATATCAAAGCCAAGATCGTTGCTGAAGGAGCCAACGGTCCCACTACACCTGAGGCAGATAAGATATTTCTAGAGAGGAATATCATGGTGATCCCTGACATGTACCTGAATGCTGGAGGTGTGACGGTCTCCTACTTTGAGTGGCTGAAGAACCTTAACCACGTCAGTTATGGCAGACTGACCTTCAAATACGAAAGGGACTCAAACTACCATCTCCTTATGTCTGTCCAGGAAAGTCTGGAAAGGAAGTTTGGGAAACATGGTGGAGCCATACCTATTGTCCCCACATCTGAATTTCAAGACAGGATTGCTCAAATCATGCGCACAGCCAACAGGTATAACCTTGGGCTGGACCTGAGGACAGCTGCCTATGTCAACGCCATTGAGAAAGTCTTCAAAGTGTACCATGAGGCTGGCCTTACGTTCACATAGACGGTTGTATTATTCACCTGACTCTGTATATCTAAGTCTGCACAGACCTGAGTCACTTAACCCTACAGCACCTCACGTTTACATTTTATACATCAAAATGTGTCATATCATTTATGCATGTGGTTACCAATATGCATCTTTAGAAGCTTCTATTCTTGTCTAGTTCATCATCCTTTCAAATATTCATAGCTTTTAGAAAAGCCTTTAAGCCAAAGTCCCTTTAATTCACTCTCTTTGTCACATTTCAGAGCATAGTGGGAATGTCTTGCCAGGAAACACCAAAAATCGATAACAATCTAACTTATTTTAGAGCTACAGTATTTCAAAGCTTTGTAATGTTTTCTTTAGGCCATGTGTTAATGAAGTAGTTACTGAAAACATTAAGCCTTATAGTTACAGCCGTAAACTTGAACACTGTTGTTTCTAAAACCAGTTTCTAGAATTTCCAGTTAGTTACTTTTTTCCCCCCACCCATTTTGACAAAAATGTGGTCAATTGGGAAAGGGATACAGGATGAATCTCAGGCTTTTTATATGTTACCAAAATATTGCACATAAATATCTGGTTTTGCTGCTCTTTAGAATAGTCTTCAGTAATAACCCAATGCCTTCATTTAAAAAAAAACCTTATTGGTAAATGTTTAATTTCTTAACAATATGGAAATGGTAGGGCATATATTTGGGAGAAAATGTTTATTTTTGTCATATTAGCATTTATTATGAATTAGCCTTTGAAAAAAAAAAGACTTTGTATTGCCTTTTTAAATTGTCTAAATTTA
Function
symbol |
description |
glud1a
|
Predicted to enable glutamate dehydrogenase (NAD+) activity. Predicted to be involved in glutamate catabolic process. Predicted to act upstream of or within cellular amino acid metabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including cardiovascular system; digestive system; nervous system; periderm; and pronephros. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; and hypoglycemia. Orthologous to human GLUD1 (glutamate dehydrogenase 1).
|
glud1b
|
Predicted to enable glutamate dehydrogenase (NAD+) activity. Predicted to be involved in glutamate catabolic process. Predicted to act upstream of or within cellular amino acid metabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including blastomere; digestive system; fin; mesoderm; and tail bud. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; hypoglycemia; and late onset Parkinson's disease. Orthologous to several human genes including GLUD1 (glutamate dehydrogenase 1).
|
glud1
|
Enables anion binding activity and glutamate dehydrogenase (NAD+) activity. Involved in glutamate biosynthetic process; glutamate catabolic process; and positive regulation of insulin secretion. Located in endoplasmic reticulum and mitochondrion. Implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; and hypoglycemia. Biomarker of Alzheimer's disease.
|
gdh2
|
Enables glutamate dehydrogenase (NAD+) activity. Involved in nitrogen compound metabolic process. Located in mitochondrion.
|
gdh1
|
Enables glutamate dehydrogenase (NADP+) activity. Involved in glutamate biosynthetic process. Located in nucleus. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; hypoglycemia; and late onset Parkinson's disease. Orthologous to human GLUD1 (glutamate dehydrogenase 1) and GLUD2 (glutamate dehydrogenase 2).
|
GO:
id |
name |
namespace |
GO:0032024
|
positive regulation of insulin secretion |
biological_process |
KEGG:
id |
description |
K00261
|
GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) |
RNA
Neighbor
Expression