LOC103029394 (smad4a,LOC108435141,LOC107559658,LOC107668639,LOC107741365,LOC104924734,LOC107373891)


Basic Information

Item Value
gene id LOC103029394
gene name smad4a,LOC108435141,LOC107559658,LOC107668639,LOC107741365,LOC104924734,LOC107373891
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035916.1
NCBI id CM008319.1
chromosome length 36262418
location 3178378 ~ 3189700 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022680893.1
TCTTTCCTGTGTGCGCATGCGCAGTTCTCCATATCGAAATCAGGGCAGCTGCTGGGGCGTTAAGATGGTGCCTGTGGACCGAGGCTCCgctgtttattttagtgtgaaGCTGCGCGTGTTCTCGCTTTTTCGTTAAAAACACGATATTGTGCGAGTCGCGGACACTTATTCTGCGCTTGCGGGGGTCTGTGGAAGTTTGCCGGGCTCTGAAAGCTGCGGTTTTAGTCGGTAAACAGCTCCGTGGGCTGAAGTTTGAGCGGCGCGCTGCCGCTCCGCTCCGAACTCAGGAGATCGGATTTAATTAACGGCTGAAGAAAGTGGATTTAAATCCGGAGTGATTCGATTCGCATCGgcTGAGACTTGAATGGACACACTGCTGCAGTCTGTGCTGGTGCTTTCGCCTCGCTGAACACCCGGTGAAACAGTTGTGAGGAGTCACGCAGTTGGAGACTGGTCAAGATGTCGATCACAAACACGCCCACCAGTAACGATGCTTGCCTGAGCATTGTGCACAGTTTGATGTGTCACAGGCAGGGTGGGGAGAGCGAGACGTTTGCAAAGCGGGCCATCGAGAGCCTGGTGAAGAAGCTGAAGGAGAAGAAGGATGAGCTTGACTCTCTCATCACTGCCATCACCACCAATGGAGCTCATCCCAGCAAGTGTGTAACCATCCAGCGCACTCTGGATGGACGGCTTCAGGTGGCTGGGCGCAAAGGTTTCCCTCATGTGATTTATGCCAGACTGTGGCGATGGCCAGACCTCCACAAGAACGAACTGAAGCACGTTAAATACTGCCAGTTTGCATTCGACCTGAAGTGTGACAGCGTCTGTGTGAACCCTTACCACTATGAGCGGGTGGTCTCAGCAGGGATAGACCTTTCTGGACTGACACTGTCTGGTTCTGGTTCGCTGGTCAAAGACGAGTATGACTACGATTGTCCATCATCTTTACCCAGTTCTGAGGGACACATCCAGACCATTCAGCACCCTCCTTCTAGACCTGTGGCTCCAGAGGCCTTCAGCACCCCTGCTCTGCTTCCTGCAGCAGACGGCAGCAGCTCGGCCTCCTCCTCCGCCTTCTCCAGCATTGCGGTGGGACCCACAACTCATTCCAATAGTCTTCTCTCAGGGAGCCATAGCAGCGAGAGTCTGCTACAGATTGCTTCAGGGACAGGGCAGGGAACGCAGCAGAATGGCTTTCCTCCAGGACAGACCTCCACGTACCACCACAATACCACCTCCACCTGGACAAGAAACAACAATTTTACACCCACTGTGCCTCACCCACAGAATGGACACATACAGCACCACCCACCTATGCACCACCCTGGACACTACTGGCCAGTTCACAATGAAATAGCATTTCAACCTCCTATTTCCAACCACCCTGCTCCGGAGTACTGGTGCTCCATCGCCTATTTTGAGATGGATGTACAGGTGGGGGAGACCTTTAAGGTTCCTTCGAATTGCCCCATCGTCACTGTGGATGGGTATGTGGACCCTTCAGGTGGAGACCGCTTCTGTCTGGGCCAGCTGAGTAACGTGCACAGAACTGAAGCCATTGAGAGAGcaagATTGCACATCGGTAAGGGCGTCCAGCTGGAGTGTAAAGGTGAGGGTGACGTGTGGGTGCGGTGCCTGAGCGATCACGCTGTCTTCGTTCAGAGCTACTACCTGGACCGAGAGGCCGGCCGTGCTCCTGGAGACGCCGTGCACAAGATCTACCCGAGTGCGTACATCAAGGTGTTTGACCTGCGGCAGTGCCACCGGCAGATGCAGCAGCAGGCGGCCACAGCTCAGGCAGCGGCTGCAGCacaggcagcagcagtggctGGTAATATCCCTGGACCTGGATCTGTGGGAGGAATCGCACCTGCAATCAGTTTGTCTGCAGCTGCAGGGATTGGTGTGGACGACCTGCGCCGGCTGTGTATCCTGCGGATGAGCTTTGTGAAGGGCTGGGGGCCGGACTACCCCAGGCAGAGCATTAAGGAGACGCCGTGTTGGATCGAGATCCACCTCCACCGGGCCCTGCAGCTGCTGGACGAGGTGCTGCACACCATGCCCATCGCCGATCCTCAGCCCCTGGACTAAAAGCTCATCTTCCCTTGTTGCACCTCCTACTGTTAGAACCTGAGGATCTGAACTGAGTggacttttttttaatcctctCCTATATCAATTtctcgtttttctttttttcctcgtTTTTCCTTTTGGAAGTGCAACCAGACAACTTCAAGCCGCTGAACTGTGTGAGCCAGTGCTGATGAGCCCGTCCAACGCCAGCCTTCATCCTTGTGTTAAAAACCCAGAGAAAAGGCAGAGTGAAAGATGAAGATCTGTTGCCTTGCCTTTCTTTAAGTGGACTTTTTAAAGTGGGCTTTTTATTATTGGAACAAGGATGGAACGTTGGTACCATTTGATGCAACTATAACTTGTCACTTTTTGCATCTCACAAataatagtaaaacaaaaatatacagagaGCAATGGTGGCAAGTACCATATGCACTGCTGGATGGACCTAAAGTGATCTAGGAAAAGAGGATTCTGAAATGGTGCACCGATTCTGGTTAAAGAAACAATCGAAAAGATGtgattttctgcatataaacttttttttcgtattgttttattttttctttttcagttggCTGAACACCGTGCCTTTGAACAAAGACGTTCAGGGACACCGTGTAAGTTTGAGTACCAGAGGAGTTGAGATTATCACTGCTTTACAGGGTAAAATCTGATGAAATACGTCATTGGCTTATTGATCCGTCATAGTTACTGACCTGTGTATTAATAATGTAGTAATTTGAGCTGGAATTGGGCTGTTTTGAGGATTTATACAAAAGATAAAAGcgaaaaaagagaacaaaagagaaaagtgGACACGCTAGGGCtgatttaatgcattatttttatcATCACAATAGGAGTTTTCGTGATGATAGACACAGAAAGAGCTGTGATCATTACAAATCTTACTCTGTGTGAGAGAACCTTAGCTCCAGCATTTCAAAGGTCTTCACACAATGTTTTTCTCCAGAGTTTCTCCTTCTTTCCTGTGATggtagaacagaacagaacggTTATTCTATACGTTTTTTAATCCCAGTATTCGCTCcacagtgtgtgcagtgtctGTAAACTCTGTATTAGGTCAGTTTAATAGGAAGAAAGTCTATTCAAGCTCCTCTTGGTCTGTAAAATATGCTGCAGGTAAGGTAAGCTGTGCGAGTCCGTTTCAGGtcaaattcatcattttttttccctcctttttttttttttttttttagctaaatgaTGGCATGATTGCTGAATATAGCACTTTATTGATGTGTCCCCGCCCCTCCTTTTTCCACGACAGAATCACTCCCTCATCCATCAGCAGAACTGTGCTGTACCGCCCAAATATTAAAGGGGAATTCTGTTTTCATGAGTCAccaagagttttactaaaagagaaattaaagcATGTTGAAC
>XM_022680894.1
TCTTTCCTGTGTGCGCATGCGCAGTTCTCCATATCGAAATCAGGGCAGCTGCTGGGGCGTTAAGATGGTGCCTGTGGACCGAGGCTCCgctgtttattttagtgtgaaGCTGCGCGTGTTCTCGCTTTTTCGTTAAAAACACGATATTGTGCGAGTCGCGGACACTTATTCTGCGCTTGCGGGGGTCTGTGGAAGTTTGCCGGGCTCTGAAAGCTGCGGTTTTAGTCGGTAAACAGCTCCGTGGGCTGAAGTTTGAGCGGCGCGCTGCCGCTCCGCTCCGAACTCAGGAGATCGGATTTAATTAACGGCTGAAGAAAGTGGATTTAAATCCGGAGTGATTCGATTCGCATCGgcTGAGACTTGAATGGACACACTGCTGCAGTCTGTGCTGGTGCTTTCGCCTCGCTGAACACCCGGTGAAACAGTTGTGAGGAGTCACGCAGTTGGAGACTGGTCAAGATGTCGATCACAAACACGCCCACCAGTAACGATGCTTGCCTGAGCATTGTGCACAGTTTGATGTGTCACAGGCAGGGTGGGGAGAGCGAGACGTTTGCAAAGCGGGCCATCGAGAGCCTGGTGAAGAAGCTGAAGGAGAAGAAGGATGAGCTTGACTCTCTCATCACTGCCATCACCACCAATGGAGCTCATCCCAGCAAGTGTGTAACCATCCAGCGCACTCTGGATGGACGGCTTCAGGTGGCTGGGCGCAAAGGTTTCCCTCATGTGATTTATGCCAGACTGTGGCGATGGCCAGACCTCCACAAGAACGAACTGAAGCACGTTAAATACTGCCAGTTTGCATTCGACCTGAAGTGTGACAGCGTCTGTGTGAACCCTTACCACTATGAGCGGGTGGTCTCAGCAGGGATAGACCTTTCTGGACTGACACTGTCTGGTTCTGGTTCGCTGGTCAAAGACGAGTATGACTACGATTGTCCATCATCTTTACCCAGTTCTGAGGGACACATCCAGACCATTCAGCACCCTCCTTCTAGACCTGTGGCTCCAGAGGCCTTCAGCACCCCTGCTCTGCTTCCTGCAGCAGACGGCAGCAGCTCGGCCTCCTCCTCCGCCTTCTCCAGCATTGCGGTGGGACCCACAAATACCACCTCCACCTGGACAAGAAACAACAATTTTACACCCACTGTGCCTCACCCACAGAATGGACACATACAGCACCACCCACCTATGCACCACCCTGGACACTACTGGCCAGTTCACAATGAAATAGCATTTCAACCTCCTATTTCCAACCACCCTGCTCCGGAGTACTGGTGCTCCATCGCCTATTTTGAGATGGATGTACAGGTGGGGGAGACCTTTAAGGTTCCTTCGAATTGCCCCATCGTCACTGTGGATGGGTATGTGGACCCTTCAGGTGGAGACCGCTTCTGTCTGGGCCAGCTGAGTAACGTGCACAGAACTGAAGCCATTGAGAGAGcaagATTGCACATCGGTAAGGGCGTCCAGCTGGAGTGTAAAGGTGAGGGTGACGTGTGGGTGCGGTGCCTGAGCGATCACGCTGTCTTCGTTCAGAGCTACTACCTGGACCGAGAGGCCGGCCGTGCTCCTGGAGACGCCGTGCACAAGATCTACCCGAGTGCGTACATCAAGGTGTTTGACCTGCGGCAGTGCCACCGGCAGATGCAGCAGCAGGCGGCCACAGCTCAGGCAGCGGCTGCAGCacaggcagcagcagtggctGGTAATATCCCTGGACCTGGATCTGTGGGAGGAATCGCACCTGCAATCAGTTTGTCTGCAGCTGCAGGGATTGGTGTGGACGACCTGCGCCGGCTGTGTATCCTGCGGATGAGCTTTGTGAAGGGCTGGGGGCCGGACTACCCCAGGCAGAGCATTAAGGAGACGCCGTGTTGGATCGAGATCCACCTCCACCGGGCCCTGCAGCTGCTGGACGAGGTGCTGCACACCATGCCCATCGCCGATCCTCAGCCCCTGGACTAAAAGCTCATCTTCCCTTGTTGCACCTCCTACTGTTAGAACCTGAGGATCTGAACTGAGTggacttttttttaatcctctCCTATATCAATTtctcgtttttctttttttcctcgtTTTTCCTTTTGGAAGTGCAACCAGACAACTTCAAGCCGCTGAACTGTGTGAGCCAGTGCTGATGAGCCCGTCCAACGCCAGCCTTCATCCTTGTGTTAAAAACCCAGAGAAAAGGCAGAGTGAAAGATGAAGATCTGTTGCCTTGCCTTTCTTTAAGTGGACTTTTTAAAGTGGGCTTTTTATTATTGGAACAAGGATGGAACGTTGGTACCATTTGATGCAACTATAACTTGTCACTTTTTGCATCTCACAAataatagtaaaacaaaaatatacagagaGCAATGGTGGCAAGTACCATATGCACTGCTGGATGGACCTAAAGTGATCTAGGAAAAGAGGATTCTGAAATGGTGCACCGATTCTGGTTAAAGAAACAATCGAAAAGATGtgattttctgcatataaacttttttttcgtattgttttattttttctttttcagttggCTGAACACCGTGCCTTTGAACAAAGACGTTCAGGGACACCGTGTAAGTTTGAGTACCAGAGGAGTTGAGATTATCACTGCTTTACAGGGTAAAATCTGATGAAATACGTCATTGGCTTATTGATCCGTCATAGTTACTGACCTGTGTATTAATAATGTAGTAATTTGAGCTGGAATTGGGCTGTTTTGAGGATTTATACAAAAGATAAAAGcgaaaaaagagaacaaaagagaaaagtgGACACGCTAGGGCtgatttaatgcattatttttatcATCACAATAGGAGTTTTCGTGATGATAGACACAGAAAGAGCTGTGATCATTACAAATCTTACTCTGTGTGAGAGAACCTTAGCTCCAGCATTTCAAAGGTCTTCACACAATGTTTTTCTCCAGAGTTTCTCCTTCTTTCCTGTGATggtagaacagaacagaacggTTATTCTATACGTTTTTTAATCCCAGTATTCGCTCcacagtgtgtgcagtgtctGTAAACTCTGTATTAGGTCAGTTTAATAGGAAGAAAGTCTATTCAAGCTCCTCTTGGTCTGTAAAATATGCTGCAGGTAAGGTAAGCTGTGCGAGTCCGTTTCAGGtcaaattcatcattttttttccctcctttttttttttttttttttagctaaatgaTGGCATGATTGCTGAATATAGCACTTTATTGATGTGTCCCCGCCCCTCCTTTTTCCACGACAGAATCACTCCCTCATCCATCAGCAGAACTGTGCTGTACCGCCCAAATATTAAAGGGGAATTCTGTTTTCATGAGTCAccaagagttttactaaaagagaaattaaagcATGTTGAAC

Function

symbol description
smad4a Enables sequence-specific DNA binding activity. Contributes to transcription cis-regulatory region binding activity. Acts upstream of or within convergent extension; determination of ventral identity; and striated muscle tissue development. Located in nucleus. Part of SMAD protein complex. Is expressed in several structures, including digestive system; head; heart; immature eye; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including female reproductive organ cancer (multiple); hereditary hemorrhagic telangiectasia; juvenile polyposis syndrome; juvenile polyposis-hereditary hemorrhagic telangiectasia syndrome; and seminoma. Orthologous to human SMAD4 (SMAD family member 4).

NR:

description
PREDICTED: mothers against decapentaplegic homolog 4-like isoform X1

GO:

id name namespace
GO:0007179 transforming growth factor beta receptor signaling pathway biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K04501 SMAD4; mothers against decapentaplegic homolog 4

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022680893.1 True 3492 mRNA 0.49 12 3178378 3189700
XM_022680894.1 False 3366 mRNA 0.49 11 3178378 3189700

Neighbor

gene id symbol gene type direction distance location
LOC103031084 NA coding upstream 4822 3170196 ~ 3173556 (+)
LOC111195007 LOC108435126 coding upstream 22263 3142848 ~ 3156115 (+)
LOC103030033 NA coding upstream 46742 3125086 ~ 3131636 (+)
LOC103031401 LOC108435143,LOC108276558 coding upstream 54126 3098197 ~ 3124252 (+)
LOC103030349 LOC108435127 coding upstream 93373 3063895 ~ 3085005 (+)
LOC103042678 NA coding downstream 1052468 4242168 ~ 4244029 (+)
LOC111195096 NA coding downstream 1143173 4332873 ~ 4337695 (+)
ranbp3l NA coding downstream 1165234 4354934 ~ 4379352 (+)
LOC103029159 NA coding downstream 1193431 4383131 ~ 4389029 (+)
LOC103026990 ucp3,LOC103026990,LOC108433282,LOC108277383,LOC107578242,LOC105890488,LOC107743402 coding downstream 1248340 4438040 ~ 4444030 (+)
G173045 NA non-coding upstream 14800 3163372 ~ 3163578 (+)
LOC103032978 LOC103033194 non-coding upstream 249123 2914789 ~ 2929255 (+)
G172914 NA non-coding upstream 402360 2774888 ~ 2776018 (+)
G172913 NA non-coding upstream 403542 2774543 ~ 2774836 (+)
G172906 NA non-coding upstream 485247 2667370 ~ 2693131 (+)
G173048 NA non-coding downstream 9079 3198779 ~ 3199215 (+)
G173049 NA non-coding downstream 10863 3200563 ~ 3200788 (+)
G173050 NA non-coding downstream 11174 3200874 ~ 3201620 (+)
G173079 NA non-coding downstream 189179 3378879 ~ 3379158 (+)
G173090 NA non-coding downstream 671405 3861105 ~ 3862194 (+)
LOC103031931 LOC103031931,LOC108435131,LOC104953549 other upstream 452302 2718609 ~ 2726076 (+)
G172770 h2afvb,h2afva,LOC107386217,LOC105007341,LOC107668744,LOC107599604,LOC103039302 other upstream 1181016 1994708 ~ 1997362 (+)
G172725 ogdh,LOC107554543,LOC107714098,LOC107656768 other upstream 1322624 1853282 ~ 1855754 (+)
LOC103041266 NA other upstream 1328162 1839351 ~ 1850216 (+)
G172552 NA other upstream 1549573 1626799 ~ 1628805 (+)
unc5c unc5c,LOC108435138,LOC108277026,LOC105911728,LOC106564027,LOC105025160,LOC106568183 other downstream 275433 3465133 ~ 3739736 (+)
G173094 NA other downstream 550602 3740302 ~ 3743205 (+)
G173111 LOC108435134,LOC108277016 other downstream 719242 3908942 ~ 3931991 (+)
gdnf gdnf,LOC107653769,LOC107752627,LOC107692037,LOC107569368,LOC107727951 other downstream 928334 4118034 ~ 4130482 (+)
G173397 NA other downstream 1553869 4743569 ~ 4744249 (+)

Expression


Co-expression Network