LOC103021760 (loxl2,loxl2a,LOC108440557,LOC107720722,LOC107678026,LOC107705082,LOC107687596,LOC107553706)



Basic Information


Item Value
gene id LOC103021760
gene name loxl2,loxl2a,LOC108440557,LOC107720722,LOC107678026,LOC107705082,LOC107687596,LOC107553706
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035916.1
NCBI id CM008319.1
chromosome length 36262418
location 18349905 ~ 18388403 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_022681166.1
ATGGCGGTGCTGTCCGGCTGTCTGCTGGTCGTGGTGGGTGTGTTGGGGGTGATGTCGGAACCCCCGGCCCCCCGGATCCAGCTGCGTCTGGCCGGGGATAAGCGTAAACACTATGAGGGCCGGGTGGAGGTGCTGTATAATAACGAGTGGGGAACGGTGTGCGACGACGACTTCGACATGTCCGCTGCCCACGTGGTCTGCAGGGAGCTCGGGTACCTGGGAGCCGTGTCCTGGTCTCCCTCTGCCAAATTCGGAAAAGGAGAAGGGCGGATATGGCTGGATAACGTCCACTGCACGGGCAGGGAGACGTCTCTAGCTGACTGTCCGTCAAACGGCTTGGGCGTGTCCGACTGCAGACACTCTGAGGATGTGGGTGTGGTCTGCACCCAGAAACGAATCCCGGGCTTCCAGTTCATCAGCAGCACCAGCAACGACGTGGAGACTCTGGACGTTCGGGTGGAGGATGTTCGTATCCGGGCGACGTATTCCCAGCGTAAACGTGTTCCCATCACAGAGGGCTTTGTGGAGCTGAAGGATGGTGGGAAATGGAGGCAGATTTGTGACGAGGATTGGAACATGATGAACAGCAGGGTTGTGTGCGGGATGTACGGCTTTCCTGGAGTCAAGGGCTTCAACACCAGAGCCTACAAGCTGCTGTCCCAGCGCAGGAAGAAGAACTACTGGGGGTACTCGGTGAACTGCACGGGGAACGAGGCGCACCTGTCCTCCTGCAGGATGGGGAAGGCAGTGAAGCTGGTGGGGAACAGCACCTGTGTGAAGGGGATGCCCGTGGTGGTCAGCTGTGTCCCGGGACGAGCTTTCGCCCCCACACACTCCGCCGGCTTCAGGAAGGCTTACAGACctgagcaacCCCTGGTGCGTCTGCGGGGCGGGGCTAACGTGGGAGAGGGGCGGGTGGAGGTGCTGAAGAACGGCGTGTGGGGGACGGTGTGTGATGATAACTGGGACCTGAGGGCCGCTACGGTGGTGTGCAGAGAACTGGGCTTCGGCTCGGCCAAGGAGGCGCTGACCGGAGCTCGAATGGGCCAGGGAATGGGTTCGGTGCATATGAACGAGGTGGAGTGTTCCGGGTTCGAGAAGTCGGTGACGGAGTGCTTCTTTAACAAAGAGGCTCTGGGCTGCAGTCACGAGGAGGACGCGGCGGTCCGCTGCAACGTTCCGGCCATGGGCTTCCATAACCGGCTGCGTCTGGCTGGGGGCCGGAACCCGTACGAGGGCCGGGTGGAGGTTCTGAACGAGAGGAACGGGTCTCTGGTCTGGGGGACGGTGTGCAGCGAGAGCTGGGGGATAATGGAGGCCATGGTGGTCTGCAGACAGCTGGGACTGGGATTCGCCAGCCATTCCTTCCAGgagACGTGGTACTGGCCCGGTGATGTCAGTGCGGACGGGGTGGTGATGAGCGGGGTCCGGTGTTCTGGTACTGAGATGAGTCTGTCTCAGTGTCTCCATCACGGTAAACACGTCAGCTGCCCTAAAGGAGGCGGACGCTTCGCTGCGGGGGTCTCCTGCTCTCACACTGCTCCGGACCTGGTGCTGAACGCAGAGGTGGTTGAACACACCACCTACCTGGAGGACCGCCCCATGTACGCGCTGCAGTGCGCACATGAGGAGAACTGCCTGTCCAGCACGGCCAACGCCGCCGACCACGCCTCCTACCGACGCCTTCTCCGCTTCTCCTCCCAGATCCACAACAACGGCCAGTCCGACTTCAGACCCCGAGCCGGACAGAACTCCTGGATCTGGCACGAGTGCCACAGGCACTACCACAGTATGGAGGTGTTCACTCACTACGATCTTCTGAGTCTGAACGGCACTAAAGTGGCTGAAGGTCACAAGGCCAGCTTCTGCCTGGAGGATACGGAGTGTGATGAAGGTATCCAGAAGAGATACGCCTGTGCGAACTTCGGTCAGCAGGGAATCACTGTGGGCTGCTGGGACACTTACAGACATGACATCGACTGCCAGTGGATCGACATCACCGACATTAAACCAGGAAATTACATCTTCCAGGTCGTTATTAACCCCAATTATGAAGTAGCAGAGTCTGATTACACCAACAACATCATGAGGTGTAAATGCCGCTACGATGGACATCGGATATGGACGTATAACTGTCATATAGGTGGTTCTCGGAGCTCAGATATGGATGAGTTTACAGGAATACTGACCAATCAGCTGCAGCGCAGGTAGAGCGGACGCACGAGTTATACCAAGACCAACCACTATGGGGGAGTGTTAGCCATGCTGCAGTGAACGACTCGTACCTCGCACCAATCCCAGAACTGTCTACAGTCTACGATCCATCGCTGGAGCTGGAACTGAGGAGCTCATCCTCTACGTCTTTTACATCATGAGAAAACCTCTTaactatgtttttttacacaagttcCATTAGGGGTAAATTTATGCTTCTGCGTCAGACCTGCAGTAGCCTACAGGTAGCTGTGTACTCTGCACCATAGCGAACACCATAGCCTAATGTACACCTTTCCaacactgtgattggtccacttAAGCATTGTGTGAAAGTCAACCCAACTGGCATAGAAAATGCATTAccaactaggcctgtcacgataattacaatATCGATATATCGTATTATATATCGACACAAccacaattattttactttgcGAGCAGAAtcaaattaaccaattaacatGAATAAACCTCTATTTTGACTTTTTAACAgtgattttattctcttcatggtttatttttagtataatCGTTAATGGTTAAAAAATCATTGCACTTTAAAAGTAATACCAATCtaaatgcattataccaaagcACAGTTACAATATGATTATATCATTATACCataaaatgatcttaaaatgacaataatattgtctatcgcaaaaaaattgtaaactatattttgtgcaaaaaagtttttagcattttatcaTGACAGGCATATCGCCACCTAGTGTTTCGGAGGTGTAATTGCAAGTGTAATGCTCACAGTGGTGTGGGAGGCTCGCACAGAATACTACGAAGACTCTTCGTAGATTTGATGTAGAAGCATAAACTGGCCTTAAGAGATGTTACCTTTATATGGTAATTAGGGTTGTTGTGGTATACTGGTCTTAGATACagtgatcaagcataacattatgaccacctccttgtttctacacccattatacattttttttattttttcagatccACTGCCGAAAAAAGAACAAGAGTTCTTTAGGTTTCGTtcccacagcagtgctgctggagtttttaaacactgtgtttacttactcactgtcctccactctattacacactcctacct

Function


symbol description
loxl2a Predicted to enable calcium ion binding activity; copper ion binding activity; and protein-lysine 6-oxidase activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in several cellular components, including basement membrane; chromatin; and endoplasmic reticulum. Predicted to be active in extracellular space. Is expressed in eye; intersegmental vessel; midbrain; midbrain hindbrain boundary; and notochord. Orthologous to human LOXL2 (lysyl oxidase like 2).
loxl2 Enables metal ion binding activity; oligosaccharide binding activity; and protein-lysine 6-oxidase activity. Involved in several processes, including collagen fibril organization; peptidyl-lysine oxidation; and response to copper ion. Located in several cellular components, including chromatin; endoplasmic reticulum; and nucleoplasm. Colocalizes with collagen-containing extracellular matrix.

NR:

description
PREDICTED: lysyl oxidase homolog 2A-like

GO:

id name namespace
GO:0006898 receptor-mediated endocytosis biological_process
GO:0032332 positive regulation of chondrocyte differentiation biological_process
GO:0002040 sprouting angiogenesis biological_process
GO:0030199 collagen fibril organization biological_process
GO:0001837 epithelial to mesenchymal transition biological_process
GO:0045892 negative regulation of transcription, DNA-templated biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0001935 endothelial cell proliferation biological_process
GO:0001666 response to hypoxia biological_process
GO:0043542 endothelial cell migration biological_process
GO:0005604 basement membrane cellular_component
GO:0005634 nucleus cellular_component
GO:0005694 chromosome cellular_component
GO:0016020 membrane cellular_component
GO:0005507 copper ion binding molecular_function
GO:0004720 protein-lysine 6-oxidase activity molecular_function
GO:0005044 scavenger receptor activity molecular_function

KEGG:

id description
K00280 LOXL2_3_4; lysyl oxidase-like protein 2/3/4

RNA


RNA id representative length rna type GC content exon number start site end site
XM_022681166.1 True 3319 mRNA 0.52 14 18349905 18388403

Neighbor


gene id symbol gene type direction distance location
LOC103046908 NA coding downstream 32343 18307853 ~ 18317562 (-)
LOC103046193 LOC103046193,LOC108440561,LOC107553709,LOC107720725,LOC107678020,LOC107705087,LOC107586120 coding downstream 47863 18257392 ~ 18302042 (-)
LOC103045884 NA coding downstream 123728 18224236 ~ 18226177 (-)
pbdc1 pbdc1,LOC107678025,LOC107687677,LOC107730415,LOC107705089 coding downstream 168826 18175471 ~ 18181079 (-)
LOC103043435 NA coding downstream 214776 18103831 ~ 18135129 (-)
tacc1 NA coding upstream 16600 18405003 ~ 18449203 (-)
LOC103023096 ddhd2,LOC108440555,LOC107678050,LOC107553701,LOC107720719 coding upstream 70601 18459004 ~ 18482116 (-)
LOC103025514 NA coding upstream 177298 18565701 ~ 18570062 (-)
LOC103025819 rassf2 coding upstream 182826 18571229 ~ 18577765 (-)
LOC103026456 kcnip3,kcnip3b,LOC107092684,LOC106535652,LOC103473704,LOC103026456,LOC108440143,LOC107678047,LOC107572711,LOC107720714 coding upstream 191348 18579751 ~ 18595814 (-)
G177559 NA non-coding downstream 1251 18348298 ~ 18348654 (-)
G177555 NA non-coding downstream 11073 18338544 ~ 18338832 (-)
G177546 NA non-coding downstream 11439 18263803 ~ 18338466 (-)
G177551 golga7,LOC108276767,LOC107553707,LOC107687624,LOC107678053 non-coding downstream 21726 18324755 ~ 18328179 (-)
G177545 NA non-coding downstream 82398 18262603 ~ 18267507 (-)
G177584 NA non-coding upstream 146482 18534885 ~ 18537687 (-)
G177589 NA non-coding upstream 160607 18549010 ~ 18550867 (-)
G177596 NA non-coding upstream 172949 18561352 ~ 18565313 (-)
LOC111195060 NA non-coding upstream 231796 18620199 ~ 18624721 (-)
G177605 NA non-coding upstream 237886 18626289 ~ 18626532 (-)
G177526 NA other downstream 175380 18171849 ~ 18174525 (-)
stoml2 stoml2,LOC107686459,LOC107688641,LOC107569390,LOC106563216 other downstream 2559261 15780555 ~ 15790644 (-)
LOC111194989 NA other downstream 2784442 15528296 ~ 15565463 (-)
LOC103044788 wnt11,wnt11r,LOC107686210,LOC107589704,LOC107747044 other downstream 3679235 14657270 ~ 14670670 (-)
G176138 NA other downstream 4277221 14069749 ~ 14072684 (-)
G177568 NA other upstream 9179 18397582 ~ 18403008 (-)
nsd3 whsc1l1,LOC107720716,LOC107687514,LOC107705078 other upstream 97239 18485642 ~ 18531635 (-)
LOC111195059 NA other upstream 226489 18614892 ~ 18618612 (-)
LOC103029522 LOC103029522,LOC107746207,LOC108440152,LOC107689072,LOC107658587,LOC107583405,LOC107758669,LOC106564675,LOC105890914 other upstream 498625 18887028 ~ 18934600 (-)
G177704 NA other upstream 702743 19091146 ~ 19092146 (-)

Expression



Co-expression Network