LOC103025998 (kdm5b,LOC107600688,LOC107685701,LOC107561016,LOC107749493)


Basic Information

Item Value
gene id LOC103025998
gene name kdm5b,LOC107600688,LOC107685701,LOC107561016,LOC107749493
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035918.1
NCBI id CM008321.1
chromosome length 32506130
location 22996094 ~ 23028601 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022682657.1
CGTTTCCTAAAGTGGCTGAGGATGTTAATAGTGGGAGTTCAGGTGTGATCAGTGAGTGTAATGTTGGAGATTCGGCTGTAACTCTTTATTTTCTTCCACTTTGAGCAGTTTAGCAGTTTCTACATGTCCTCATCTGGATGCAGTTCCCCAGAATGACCCAGCCTCGACCCAGCGAGTTTATTCCGCCGCCGGAGTGCCCTGTGTTTGAGCCCAGTTGGGAAGAATTCTCCGACCCGTTCGGCTTCATCAACAAGATCCGCTCCATCGCAGAGAACACCGGCATCTGTAAGATCCGCCCGCCGCCGGGCTGGCAGCCACCATTTGCCTGTGATGTGGACAGACTGCACTTCACCCCTCGCATCCAGCGTCTGAACGAGCTGGAGGCTCAGACCCGAGTCAGGCTCAACTTTCTGGACCAGATTGCCAAGTTCTGGGAGCTGCAGGGCTGCACGCTGAAAATCCCTCACGTGGAGCGCAAGTCTCTGGACCTCTACCAGCTCTACAAGGTGGTGTCGGAGGAGGGTGGCTTTGAACAGGTCTGTAAAGAGCGGAAATGGACCCAGATCTCAACGAGGCTGGGCTTTGCCCCAGGCAAGGCTGTAGGTTCTCATCTGCGGTCCCACTACGAGAGGGTGCTGTACCCGTACTACCTGTTCCAGATCGGGGTCAACCTTTTGacCTCACAGAAGCCCACGCTCACCAACGACACCAAAGATAAGGAGTATAAATCTCATGATTTACCCCAGCGCCAGTCAGTTCAGCCGGCCGAGACCACCACCATCGCCCGCAGAGCAAAGCGCACCGAGGGCCGCTGCGTCAAAACGGAGCAGGGCGAGCCGTGTGAGAACCGACCCAACCTGAGGAGAAGGATGGGCTCTTGTGTGGCAAAATCTGAACCAgTTCTTAACATTCCAGTCCAGGTCAAACAGGAGCCTGTGGAGCTGGCTGTACCTGCACCACCTGAGGGAGAAAAGTCAAAGGTGGAGCAGTACATATGTTTGgtgtgtgggggtgggggtgatgAGGACCGCCTGCTGCTGTGTGATGGGTGTGATGACAGTTACCACACATTCTGTCTGATCCCACCACTCCACGATGTTCCCAAAGGGGACTGGAGATGCCCCAAGTGCCTGGCCCAGGAGTGTGGAAAGCCTCAGGTGGCGTTCGGGTTTGAGCAGGCCTCCCGGGACTATACCCTCCGCTCTTTTGGAGACATGGCAGACTCCTTCAAGTCGGACTATTTCAACATGCCTGTTCACATGGTTCCTACAGAGCTGGTGGAGAAGGAGTTCTGGCGTCTGGTCAGCACCATAGAGGAAGACGTGACTGTAGAGTATGGGGCAGATATTGCGTCCAAGGACTTTGGAAGTGGTTTCCCTGTTAAAAACGGCTCCTTCAAGGTCACACCTGATGAAGAGCATTATGTCACAAGCGGCTGGAACCTGAACAACATGCCAGTGCTGGACTCGTCGGTGCTGACTCATATTACAGCCGACATATGTGGCATGAAGCTGCCCTGGCTCTATGTTGGCATGTGCTTCTCCTCATTCTGCTGGCACATTGAGGATCACTGGAGCTACTCCATCAACTATCTGCACTGGGGCGAGCCGAAGACGTGGTACGGTGCCCCCGGCTACGCTGCGGAGCAATTGGAGATGGTAATGAAGAAACTGGCTCCCGAGCTCTTTGAGTCCCAGCCAGATCTGCTCCACCAGCTGGTCACCATCATGAACCCCAATCTCCTAATGGAGCATGGCGTCCCGatCTACCGTACTAATCAGTGTGCGGGAGAGTTCGTCATCACCTTCCGAGCCTATCACAGCGGCTTCAACCAGGGCTTTAACTTCGCAGAGGCAGTGAACTTCTGCACAGTGGACTGGATGTCTCTGGGCCGGCAGTGTGTGGCGCATTACCGCTCCCTGAACAGATACTGCGTCTTCTCCCATGATGAGATGGTGTGTAACATCGCAGCCAAAGCAGACAACCTGGATCTTGTGCTGGCGTGCGCCATCCAGAAGGACATGAGCGCCAtgatggaggaggagaaggagctGCGGGAGAGGGCCTACAAGCTGGGGGTGTGGCATTCCCAGCAGGTGGATTATGAGGAGCTGCCAGACGAGGAGCGGCAGTGTATAAAGTGCAGGACCACCTGTTTCCTGTCTGCAATCACCTGCCCCTGCAGCCCCACCCAGCTGGTCTGTCTGCACCACCTGCAGGACCTGTGCTCCTGTGCCTGCAGCAACTACACACTGAAttatAAATACACACTGGGCTTGTTAAATCAGATGTTTAAGTCTGTGGCGGGGCGTGCTGTGTCGTATGATGACTGGGCTTCTAAGGTTAACAAGATGTTAAAACCTGAGCGGGAGAAAAACGATGTGGAAGATCTCCGGGCGCTAATGGTGGAGGCGGAGAAGAAGATGTACCCTGAAATGGACCTGCTGCGGCATTTACGGCAGATCATCCAGGAGGCAGAGAAGAGTGCGGCGATGGCCCAGCAGCTCCTTAACGGCAAAAGGCAGACCCGgtatCGGACCGGAGGAGGGAAGTCTCAGAATCAGCTTACTGTGGAGGAGCTGAGGTCATTCATACAGCAGCTCTATGATCTGCCTTGCACCATCCGACAGGTTCCCTTCCTTAAGGCTCTGCTGACCCGTATTGAGGAGTTTCAGGCGCGTAGTGCTGATCTCCTGGCGGAGGACATGCCCGGCTCGTCGGCGCTCCAGGGCTTGGTGGACGAGGGCGCCGGGCTGGACGTGGAGTTGCCTGAGCTGGCGGTGCTCAGGCAGAGGCTGGAGCAAGCCCGGTGGGTGGAGGCGGTGCAGCAGGCCGGCGAGCAGCCGGCCAGCCTCAGCCTGGACTGCATGCGGAGGCTGATCGACCAGGGCGTCGGGCTGTCGGCCCACGCCTGCGTGGAGCGCACCATGGCCCGGCTGCAGGAGCTGCTCACCGTCTGCGAGCACTGGGAGGAGAAGGCCCACAACATGCTCACGGCCAGGCCTCGCTGTAGTCTGGACAGTCTGGAGACGGCCCTGCAGGAGGTAAACAGTATTCACGCTTACCTTCCCAACTGCCTTCAGCTCAAAGACTCGGTTAGCAGGGCTCGAGAGTGGATACGAGAAGCTGATGCACTTCAGTTTGGAGGACGTGTCCCTGTTCTTGCATCCTTGTCTGACCTGGTCTCAAAAGCTAAGGGCATCCCAGTCCTTCTGGAGCCCCTGGCCCGGCTGGAGAGCCTGGTTTCGGAGGTGCAAGCCTGGAAGGAAAGTGCAGCTAAAACGTTTTTGTTGAAGAACTCGTCCCTTTCGCTCCTGGAGGTCCTGTGCCCGAGGTGTGAGACGGGTTGTCCGAAATCGAGATCTAAACGAGTGAAGGAAGTCTCGCCGACAGGGAAGAAGCCTGTAAAACTGGAGTGTCTAAGTGATGTGGAACGAGCTCTGTGTGAGAGTAAAGACACGGCCTCTGCGATGGCGACTCTTGGTGAGGTTCATCAGAAGGAGCTGGAGAGCCTGTCTATCCTGAGGACCACGAACGAGACGAAATTTCATCCCACGCCCAACAGCTCGGCACCTACGGTGTGCTTGTGCCACACGGTGCCCGCTGGCCCCATGCTCCAGTGTGAACTTTGCCGCGATTCTTACCACAGCGGATGCGTGCCGGGCTTCCAGGAGACGCAGGCTGACCAGCCGTGGCTGTGCCCGCTCTGCAGTCGGTCCGAGAAGCCCCCCTTGGACAAGGTGCTGCCCCTGCTAGCTTCGTTGCAGCGGATCAGAGTCCGGCTCCCAGAGGGTGATGCGCTGCGCTACGTAATCGAGAGGACGGTGCGGTGGCAACACAAAGTGCAGCAAGTCTCACCTTTTACGCAGCAGTATAGTGGAAAGATGAGAGCTTCCTCTGGAATAGCGTCAACCCTGAGCCTGGAAGGGAGTAGTGGATCCTTCTACATGCAGCACTCCTGTATTCCTCTCAGCGTTCTGAGTCCAGagctggaggagctgctggtggaAGGCCTCCTGCTGCAGGTTACTCTTCccgagctccagcagctctatCAGGGCCTGCTCAGCCGGTTCTCCCCCTTCCATCACCTCCTGCAGAGCAGTGAGCACGACCATCAGTACCACATCGCCCAGGACAGGAGTCCCCTTCACAGAAGCCCACCACACAAGAGCCCACTCAACAGAAGCCCACCCCATAAGAGCCCGAGCCACAGAAGCCCACCCCAGAAGAGTCCAGCTTCTACAAGTCCACCTCATCAAAGCCCTCCCCACAGGAGCCCTCCCCACAGGAGCCCTCCCCACCGGAGCCCTCCCCACAAGAGCCCCACACATAAAAGCCCACCCCACAGTAAAGGACAGGATGTAGTTTTCGAGTTGCGGAAGGAAAGTGAGAAGCCAGAGAAGCATCCTAAGAGGCGTCTGGAGAAGGAGAACCCTGATGTGCAAGACAGAGACAAGATCAAAAAGCCCAAGAAAAAGAAGCCCAAGACTAACAAGGAGAGGAGACGTGAGGAGAAACGAACCATCTCCCCATCCAATTCCCTCTCAGATCCATCCTACTCCGACGATTCTGAAGAGGACTGGTCCGTGTGCTCAGCAAAGCGGTGTCTGCAGCCAGAGGGCAACGAGGTAAACTGGGTCCAGTGTGATGGCAGTTGTAACCAGTGGTTTCAccaagtgtgtgtgggtgtgtctgcTGAGCAGGCCGAAAACGAGGACTACATCTGCGTCAACTGCTCGAGAAAAAAACTGACACAATGAGGACCAAAACTGAAAGGCTTTGTGGAGTCTAATGACTTTTGAGTTTTGCACATGAGTTATAGCACCAAGTATGCACCACGTCCCGCTCCCCTGCCCTCAGATGTCCCGGCCCATCCTCCCTGTTGCTCCGGTGCTACTTTCTTCTCGATAGGACTGTTATCCCAAACCATTAAAGACCCTTGTCGCCTTTTTTCTGGTATTTTTACATTTCCTCCTATAAACTTTCTTTCTCTTGTCTAGAAGACAGACATGATACAGAGATGTACCTCAGGGGTCTCCATCCCATAAATACCTTCCTGGTAGAGGGACATCAGCTTTCCCCCACTCcccagtcaaaaaaaaaaaaaaaaaaaatattggattgTGTTTTTCCAGAAGCCACGTCACCTTCTAACACATGAAGTAATCAGAAGACTAGGctttggggattttttttttctttttttttatataaataacccCTCCACCAAATTGTATTAATTGGACTAAACAAAATGGTCTGAATTTATTTTTGGAACCCTGTTTTGGTACATGTATctaataatgttatttatttatcccaGCCTTGCTTAAGCTGGTTTGCCCTGGTTTTCATTAGCTTGAGATCTGCTCTGATCTGTAGCTTCTTGCGTTAGAGATGGTTGTACAGAATCCTGATGTAGGTCGTCCGAGTGATGTAGCAGACAGGAGAAGTGTGTGAACTATACTTTGTGACTTTTGCTGTTTCTTACTTTAAAAAGAAACGATATCAGATGTTAATTAAACTGTGGAATAAAATGGGATGTTCTCACTGATAATACACAAACACCATCA

Function

symbol description
kdm5b Enables several functions, including histone demethylase activity (H3-K4 specific); transcription corepressor activity; and zinc ion binding activity. Involved in histone H3-K4 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal recessive non-syndromic intellectual disability; breast cancer; and high grade glioma. Biomarker of esophagus squamous cell carcinoma; high grade glioma; prostate cancer; urinary bladder cancer; and uveal melanoma.

NR:

description
PREDICTED: lysine-specific demethylase 5B isoform X2

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0005634 nucleus cellular_component
GO:0016706 2-oxoglutarate-dependent dioxygenase activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K11446 KDM5, JARID1; [histone H3]-trimethyl-L-lysine4 demethylase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022682657.1 True 5576 mRNA 0.54 28 22996094 23028601

Neighbor

gene id symbol gene type direction distance location
ipo9 ipo9,LOC106566056 coding downstream 2444 22974204 ~ 22993650 (-)
shisa4 shisa4,LOC107561500,LOC107727880,LOC107655068,LOC107749490,LOC107685700 coding downstream 23689 22963708 ~ 22972405 (-)
lmod1 NA coding downstream 37048 22951724 ~ 22959046 (-)
timm17a timm17a,LOC107727855,LOC107554688,LOC106582745 coding downstream 51085 22940330 ~ 22945009 (-)
LOC103025695 sulf2a,LOC108412941,LOC107655065,LOC107749484,LOC107685697,LOC107600506 coding downstream 70426 22850141 ~ 22925668 (-)
rabif rabif,LOC107601129,LOC107581890,LOC107749491 coding upstream 4874 23033475 ~ 23036792 (-)
LOC103044418 adipor1 coding upstream 34566 23063167 ~ 23072202 (-)
LOC103045443 LOC108410710,LOC107727873,LOC107560790,LOC107685706,LOC107749489 coding upstream 45518 23074119 ~ 23082128 (-)
rnpep rnpep coding upstream 58925 23087526 ~ 23098564 (-)
c22h1orf106 LOC108410711,LOC107727857,LOC107655074 coding upstream 75653 23104254 ~ 23144408 (-)
G192232 NA non-coding downstream 33285 22961247 ~ 22962809 (-)
G192237 NA non-coding downstream 44768 22951007 ~ 22951326 (-)
G192235 NA non-coding downstream 56940 22938921 ~ 22939154 (-)
G192145 NA non-coding downstream 259852 22735091 ~ 22736242 (-)
G192149 NA non-coding downstream 307956 22684675 ~ 22688138 (-)
G192240 NA non-coding upstream 2051 23030652 ~ 23031070 (-)
LOC111195460 NA non-coding upstream 70237 23098838 ~ 23100988 (-)
G192288 NA non-coding upstream 76507 23105108 ~ 23105627 (-)
G192293 NA non-coding upstream 125981 23154582 ~ 23155042 (-)
G192335 NA non-coding upstream 186989 23215590 ~ 23223369 (-)
LOC103041653 phf20,LOC107655063,LOC107727854,LOC107561906 other downstream 192452 22786163 ~ 22803642 (-)
amhr2 NA other downstream 273189 22709549 ~ 22722905 (-)
alas1 alas1,LOC106583798 other downstream 633636 22349347 ~ 22362458 (-)
G191862 dusp7,LOC107561798,LOC107697567,LOC107677944 other downstream 1144452 21846969 ~ 21851642 (-)
elmo2 elmo2,LOC106583331 other downstream 1451263 21510924 ~ 21544831 (-)
G192251 adipor1,LOC107749488,LOC107385668 other upstream 26032 23054633 ~ 23058805 (-)
cntn2 cntn2,LOC107727196,LOC107558367,LOC107727774,LOC107602860,LOC106565094 other upstream 1010645 24039246 ~ 24105898 (-)
G192815 mdm4 other upstream 2183074 25211675 ~ 25217550 (-)
LOC111195415 tfeb other upstream 2846309 25874910 ~ 25878653 (-)
fam72a fam72a,zgc:101564,LOC108425783,LOC107590148,LOC107656018,LOC107548849,LOC107675824 other upstream 3682652 26711253 ~ 26724106 (-)

Expression


Co-expression Network