fezf2 (fezf2,fezf1,LOC108247338,LOC106530279)



Basic Information


Item Value
gene id fezf2
gene name fezf2,fezf1,LOC108247338,LOC106530279
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035918.1
NCBI id CM008321.1
chromosome length 32506130
location 31430891 ~ 31435487 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_022682793.1
AAGCGCAAGCACCCTCACAGCTCCACAAGCGCACTGCCAGATATCAGATCAGAGCGCGCGCTCTTGAGGAGAAACAGgagtaggaggaggaggaagatgatgaggagcatgaggaggaggagagggacaaaaatgtgacagtagtaccagtagtcaTCCCTGAACACATGGTGCCACTGCTTTGGGAGGAGATCTAGAAGCGCGCGCTGCCTAATGGGCATTAATCTGCCTCCCCTGGACGCCTTTTGGATGCAAATGGGAGAAGGCTGCGGCTGATGGGACAGTAGGACAGCACAAGGCGCGCGTATTAAGCTGATGCGCGTCCCGGGACACTCGGCCACGGAGAGTAGCGATAGcgagaacagcagcagcagcagcagcagcaggagcagcaacAGCTGGAGGAGCGCGAGGAGCACCAGCAACGCGAGGAGaagggaggagaagaggagaaggaggaggaggtggtggaggaAAGAGGGTCCCGACTGGAGACCGGTGGGCATGGCGAGCTCTTTGCCCATGGAGACGGCCACGTCCTGCGCGCGCCTGGAAGGCGGTAGCGGCAGCAGCGGGGTTGGCGGTGGTGGCGCGACTGCCAAACCGCTGGCCTTCTCTATCGACCGCATCATGTCAATCAAACCGCCTGGGACTAGAGCAAGCGAAGGCGCAGCAAGCGGGGGAGCGCTCGGCCCGCGCGCGCTCCCAGCGCAGCCTCCGTTCACCTACGACCTTCAGCAGGCCGCCGCGCTCATGAACTATGCCGAGCTGTGGAGGGCCGGCTTCCGTGGGGCGGCTCTGTGTGCTTCGGCGGCCGCCTGTCGAGCCGCTTTCTGCGGCGTTTGCGGAGGTGGCAACACCACAGACTCGGCGCCGCGGAGCCGCGTGATCAAACCGCAGGTGATCCACCGGGCGGTGGCCGCTGCAGCCGCCGCACCGCTCTACTATTTCGGCTGTTTTGACTCCGCGTGCCACCCGGGTGAGCTGCTAAATGGACGCTTATTTTCCTCATCcgcggcggcagcagcagcagcagcagcggcggcggcagcggcAGGGCCGCATGCGCGCGGGCACTCTCACGCAGCTCTGCTGCTCGAGGGCGCAAAGCTGGACAGGTTGCCTACCCCGCAGCACccgcacaaggagaggctgccAGGGCAGCTCGACCACGTGGTGAAGGAGAACCACAGCGCAGGAGCGGCGGTAACGGCAGGGGACCGGAGCGGCGCAGGGAAAGCACACGTCAACGGGAAAGCCAACGGCTGCGCGTCAGACGGAAAGCCCAAGAGCTTCACGTGCGAAGTCTGCGGAAAGGTGTTCAACGCGCACTATAACCTGACCCGCCACATGCCGGTGCATACAGGCGCCAGACCGTTCGTGTGTAAAGTTTGTGGGAAAGGATTCCGGCAGGCCAGCACACTGTGCAGACACAAAATCATCCACACACAAGAAAAGCCTCATAAATGTAACCAGTGTGGAAAAGCTTTCAACAGGAGTTCCACGTTAAATACACACGTCCGCATCCATGCAGGATACAAACCGTTCGTCTGTGAATTCTGTGGGAAAGGCTTTCACCAAAAAGgGAATTACAAAAACCACAAGTTGACGCACAGCGGAGAGAAGCAGTTTAAATGCTCGATCTGCAGCAAAGCCTTCCACCAGGTTTACAACCTCACCTTCCACATGCACACGCACAACGACAAGAAGCCCTTCACCTGCGCCACCTGCGGCAAAGGCTTCTGCCGCAACTTCGACCTCAAGAAGCACGTgcgcaagctgcatgacagcgGCGCCTGCACGACCCCTGCAGTCCACGAACCTTCTGTAGCAGCCCGGACCTGAGCTTAGCACGCGGGACGTTTTGCCGTAaaggacaaaaacaaaaaaaatctatctaatCAAAACGAGCGGAGCTAATGGACTGAATGAATCACTGCACAGTGAAATTGTACATAAATCcgaataaaatattatttaaaaatgtttttacctgGAAA

Function


symbol description
fezf2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Acts upstream of or within several processes, including nervous system development; neuronal stem cell population maintenance; and regulation of Notch signaling pathway. Predicted to be active in nucleus. Is expressed in several structures, including forebrain; neural keel; optic vesicle; retina; and ventricular zone. Orthologous to human FEZF2 (FEZ family zinc finger 2).
fezf1 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be located in nucleus. Is expressed in hypothalamus. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 22 with or without anosmia. Orthologous to human FEZF1 (FEZ family zinc finger 1).

NR:

description
PREDICTED: fez family zinc finger protein 2

GO:

id name namespace
GO:0021854 hypothalamus development biological_process
GO:0021879 forebrain neuron differentiation biological_process
GO:0071679 commissural neuron axon guidance biological_process
GO:0045892 negative regulation of transcription, DNA-templated biological_process
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K24502 FEZF; Fez family zinc finger protein

RNA


RNA id representative length rna type GC content exon number start site end site
XM_022682793.1 True 2000 mRNA 0.59 5 31430891 31435487

Neighbor


gene id symbol gene type direction distance location
LOC103035852 LOC108435806 coding downstream 60345 31305567 ~ 31370546 (-)
LOC103036366 prkcd,prkcdb,LOC108435819,LOC107696837,LOC107728641,LOC107656045,LOC107600299 coding downstream 143787 31238471 ~ 31287104 (-)
sfmbt1 sfmbt1 coding downstream 200062 31195822 ~ 31230829 (-)
gnl3 NA coding downstream 574342 30847297 ~ 30856549 (-)
LOC103040946 LOC108435972,LOC107714490,LOC107566450,LOC108254900 coding downstream 628383 30729235 ~ 30802508 (-)
LOC107197084 NA coding upstream 304384 31739871 ~ 31747170 (-)
thoc7 thoc7,LOC107739288 coding upstream 342870 31778357 ~ 31785020 (-)
psmd6 psmd6,LOC107656032,LOC107696848 coding upstream 405621 31841108 ~ 31844991 (-)
LOC111195428 kdm1b coding upstream 468748 31904235 ~ 31907805 (-)
prickle2 prickle2,LOC107590162,LOC107728631,LOC107656034,LOC107739290,LOC107551119,LOC107696846 coding upstream 494239 31929726 ~ 32080712 (-)
G193980 NA non-coding downstream 12365 31417749 ~ 31418526 (-)
G193978 NA non-coding downstream 16424 31411919 ~ 31414467 (-)
G193968 NA non-coding downstream 126581 31301480 ~ 31304310 (-)
G193964 NA non-coding downstream 236053 31194164 ~ 31194838 (-)
G193959 itih3,LOC108435863,LOC105912272,LOC101062864,LOC101070262 non-coding downstream 262008 31137974 ~ 31168883 (-)
G194034 NA non-coding upstream 60515 31496002 ~ 31497236 (-)
G194038 NA non-coding upstream 87255 31522742 ~ 31523803 (-)
G194040 NA non-coding upstream 111066 31546553 ~ 31571288 (-)
G194046 NA non-coding upstream 161877 31597364 ~ 31702252 (-)
G194055 LOC108435731,LOC108255025,LOC107696850,LOC107550476,LOC107739284 non-coding upstream 260785 31696272 ~ 31697770 (-)
LOC103037496 mustn1,LOC103037496,LOC103359875,LOC107091502 other downstream 236842 31170298 ~ 31194049 (-)
trnae-cuc_20 NA other downstream 256013 31174807 ~ 31174878 (-)
spcs1 spcs1,LOC107680421,LOC107744856 other downstream 599934 30809794 ~ 30830957 (-)
G193737 NA other downstream 1250765 30165761 ~ 30180126 (-)
G193541 NA other downstream 2832253 28597555 ~ 28598638 (-)
cadps cadps,LOC107549847 other upstream 15316 31450803 ~ 31654210 (-)

Expression



Co-expression Network