XLOC_000767 (c3a.3)


Basic Information

Item Value
gene id XLOC_000767
gene name c3a.3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 56274613 ~ 56320569 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001257
gtgtagtTTGGACTGTGAGCGCTGCTGGTATAAATGTGAGCGTCTGCAGGTTTACAGAAACACAGTCAGGATGGAGGTGAAGCTGCTGTTTCTCTCTGCTGTTCTTCTCTCCTCAGCGCTCCTCACACTGTGTGACCCGCTATATGTGCTGTCGGCTCCTAATCTGCTGAGAGTGGGTTCCTCTGAGAACGTGTTTGTGGAGGCGCAGGATTATTCTGGAGGACCCCTTAATGTGAGAATCTCTGTGAAGAACTTCCCAGCCAAGAATGTGGAGATGATGCAAAAAACAGTGACTCTAACCGGAGCAAAATACCAGAGTCTTACAGATATACAGATCCCTGGTGATAGAAACTACTTCTCTGATGATGAGAAGAAGCAGTATGTGTATCTGCAAGCTCACTTTCCCTCCGTGACTCTGGAGAAAGTGGTCATGGTGTCTTTTCAGTCTGGATATTTGTTTGTTCAGACGGACAAGCCCATCTACACGCCTGGCAGCAATGTTCATTACAGGATTTTTTCTATGACACCCAACTTGAAACCATTCAGTAAGCCCGGAATCACAGTGGATATCACGAATCCACAAGGCATCACGGTAGCATCAGACACGATATTTGCAGAAAAAGGTGTGAAATCTTCGATCTACAACATCCCTGAGGTTACTAGTTTGGGGATGTGGAAGGTGGTCACGCGGTATGCAAACACCCCTCAGAAGACGTTTACTGCAGAGTTTGAGGTTAAAGAATACGTTCTTCCAACATTTGAAGTGAAATTAAAAACCAGTAAATCTTTTTACTATGTGGGAGACAGCAAACCAAAGAACAACGAGGACGACAGTCTGACAGTTGACATGGAAGCCAAGTATCTGTTTGGAAAGAAGATGGATGGAAATGCGTTTGTAGTGTTTGGTGTGATGGACGGCGCGATGAAAACAAGTATTGTGAACTCTCTTCAAAAAGTTCAGgtttTCAATGGAGTAGGAACTGCAGAATTGACCAGGGAGATGATCACgaagacatttaaaaacataaaagatcTGGTTGGGAAGTCAATCTACGTTTCAGTCAACCTTTTAACCGAAAGTGGCAGTGAAATGGTGGAAGCAGAAAAGAGAGGCATTCAGATTGTGACGTCTCCGTACACCATCCATTACAAAAGAACATCACAGTTCTTCAAACCTGGAATGCCCCTGGGTGTCTCGGTTTATGTTACAAATCCTGATGAGACGCCTGCAGAAGATGTGGAAGTGGAGGTGCTGGTTGATGGAGTAGGAGGAGTCAACAGTAAAACCAAAGCCAATGGCATTGCGAAAGTGACAGTCAACACTAAGGCAGGAGTCTCTACATTGAAGATCACTGCAACGACCAGAGATCCTGAATTGGCCAATGAGCAGCAGGCGGATAAGACAATGATTGCTCAGGCCTACAAAACCAATCTTGGCTCCAAAAATTACCTGCATATCAACATTGAGTCAGCAGAGTTTGAGATTGGTGATCAAATGACAGTTTATCTGAACACTGGAGAAAGTCCAGGAGTCAAAGATCAAGATTTCACTTACATGATCTTGAGTAAAGGTCAGATTGTTCTAGCAGAAAGGTTTAAGAGGCAAGGACAAACTCTAGTCTCTCTGTCTCTACCTGTGACCAAAGACATGGTGCCGTCCTTCCGCTTCGTGGCTTATTACCATGTGGGCAAAGATGAGGTGGTGTCTGATTCAGTCTGGGTCGATGTGAAGGACACATGCATGGGAAAGCTCAAGGTCGAGGTGACAGAAAAGCAGAAATTCTATGAAACAGGAAATGAAGTCAATCTGCAAATAAGTGGAGATTTTGGAGCCCGAGTTGGTCTGGTGGTGGTTGACAAGGCTGTGCAAGTCCTTAACAAGAACAGACTCACTCAGTCGAAGATCTGGGATGTCATTGAGAAGCATGATACTGGCTGTACGGGAGGAGGTGGAAAAGACAGTATGGGGGTTTTCAGTGACGCTGGTTTGATGTTTGAGTCCGACCCTGCAGGAGGAACCAATACAAGAACAGAGCCCAAGTGTCCTGCCCCTCCAAAGAGAAAACGGAGATCTGAGAGTCTTCAGACAATCACTACAACTCTCGCTGgccaatacactgaaaaaatccGGCCATGCTGCTATGACGGGATGAGGAATAACAGAATTGGCTACACATGTGAACGGCGAGCATCATACGTCATAGATGGAGAAGAGTGTGTCAAGGCCTTCTTGCACTGCTGCAAAGAGGTGAAAAACCACAAAGAgactgaagaggaggagctgattcTGGCTCGTAAAGATGATGAAGAGACTTATGAAGAGGATTATGAAGACTATGATGACATTACATCACGCAAGCAGTTTCCTGAGAGCTGGCTTTGGGAGGAGTTTGATCTCTGTGACAAATGTTCAAAACCAAGCAAGAACAAAGTGACGTACCTGAAAGACTCTATTACTACCTGGCAGATCTTGGCAATCAGCCTCTCACCAACACACGGCATCTGTGTGGCAGAACCTGAGGAGATCGTCGTTTTTAAGAGTTTTTTCATTGACCTCAAAGTGCCTTACTCAGCTGTACGAGGTGAACAAGTGGAAATCAAGGCCATTATTCACAACTACACCCCCAAACACCTGAAGAAGGTTCGTGTGGAGTTTTTGGAGACAGCAGGTGTTTGCAGTGCTGCCAGTAAGAAAGGGAAATACAGAGCAACAGTAAATGTTGACAAGGACTCCAGCATAGCAGTTTCATTTGTGATCGTTCCAATGACACTGGAAAGTCAGCATATTGAGGTGAAAGCTTCAATATTAGATTATACAGATGGAGTTAGAAAGACCCTGAAGGTGGTGTCTGAAGGTGTGCTGACTAAATTCCAAAGCCAAAAACTGGAGCTCAATCCGGccaaaaaagGGGAGCAGCCCTTACTTCTTAGAGCTGGTATACCAGGAGATCAGGTTCCAGGCACACCCGTTCACTCGTACATCACAGTTACTGGTGAAGAAATCAGTCAGTCGATTGAGCATGCCATCAATGGAAGCTTCATGGGAGAACTTATCAAACGGCCAGGAGGATGTGGAGAGCAGAACATGGCTAAAATGACTTTGCCTGTTGTTGCTACTCATTATCTGGACAACACCAATCAGTGGGAATCTGTTGGCATTGACCGCCGTAAAGTTGCCATTAACCATATCAAAACAGGTTATGATGGGCAGCTAAAGTACCGTAAACCTGATGGATCTTACGCTATCTGGATTAACACGCCGAGTAGTACATGGCTGACAGCATATGTGGCTAAAGTCTTCGCCATGGCCAATGATTTTTTTGCTATAGAAGAAAATGTGATCTGCAGCGCCCTGAAGTGGCTGGTTATGCACAAACAACTACCAGATGGCTCTTTTAAAGAGGATGCACCTGTATATGACAAAAGTATAATGGGTGGGATAGAAGGCCAAAACACTGATGTCTCTCTGACAGCATTTGTCTTGATTGCCATGCAAGAGGGCAAAGAGATCTGTGGGGGAACAGTTGGTAGTCTGCATGAAAGCATGAGGAAGGCTGTTGCTTTCTTGAAAGATCAGCTTCCAAAACTGACCAATCCTTATGCAGTTGCTTTGACGTCCTACGCCCTGGCCAACGCTGACAGTCTTAATAAAGCAATCTTGATGATGCATTCCACTAAAGTAAACGATGAAAGGTTCTGGAATGTCCCTGAACGGCAATATTACTCAATAGAGGCGACGGCCTATGCTGTGCTGGCACTCGTGAAGGCCAAAGACTATGATACAGCAGGAGAGGCAGTGCATTGGCTGGCCAAACAAAAGTCTAGTCATGGTGGTTATGACACTACACAGGTGACCATCATGGTTTTCCAGGCTGTGGCAGAGTACCATGCGCAAACGCAAGACTTAAATAACTTTGACCTGAATGTGGAGCTGGTTGTGCCAGGAAGAAGAAAAACTGACAGATGGACCATTCAAAGAAGTAATGTGCATCTTGCGCGGTCAGGCAATGTGGATTTGAATAAGGACTTCACTGTGATTGCTAAAGGAACCGGATCAGCCATTCTCTCAGTTCTGACGCTGTACTACGCCAGACCGTTTGAGAAGAAGACTGACTGTACTTTCTTTGATCTGAGTGTCAAATTGGATAAAATCCCTGAAACAAAACCAGGAACCAATGGAACGTACAACTTCATCCTGGATTTCTTctacaaaaacaaaaaaaatgacgcCACCATGACGATTCTGGACATTGGCTTGCCAACAGGATTTGATATCGATGAAGCTGATCTTAAACAGTTGTCCACAGGGAAGGAGAGATACATTCAGAAATATGAAAAGAATAAAGTGCTCTCAGAGCGAGGATCCCTCATCATCTACTTAAACAAGGTTTCTCATGAAGTATCAGAAAAACTTGTCTTCAGAATGCACAAGACCTTTAATGTGGCTTTGCTTCAACCTGCTTCTGTCACCATATACGAGTATTACTCACCCGATGCCCGCTGTAAAAAGTACTACCACCCTGAAAGAGAAGATTCCGCCCTATACAGACTGTGTAAAggagacctgtgtgtgtgtgctgaagAAAACTGCAGTTACCAAAAGAAAAACCATGTTGATGAATCTAAGCGCTTGATTAAAGCCTGTGAACCCCATCTGGATTACATTTATAAAGCGAAATTAGTGAAGATGGACCTGAAACAAGACTCCGATATCTATCACATGAAGGTGGAGAAGACGGTGAAAGAAGGAACTGATACGGATGTTGAAGGGAAAGTGAAACAATTTTTGGCTCGTCCCAGTTGCCGAGTGAGTTTAGGACTGGTTGAAGGAAAGTCGTATCTCATCATGGGAAACTCTGTTGATCTGCCGACCCTTGGGGGAAGTCTGCAGTACGTCATAGGAGAGCAGACCTGGATTGAATACTGGCCTACAAGTGATGAAAGTAAATCTGCTGAACACAGAGATCGCTACATCGGCATGACTGCAGTCGAGAATATGTTTACCACAGGAGGATGTTTGACATAACTGCATTACACCTGTTTGTATTTTACAACACCATCTTTCCTATTTCCAAATAAATTGTGTGTAATGTCGTTTGAGCCTAATTTcttgtaattaattattaaaatcaagactgtatcaaatgaaaatgaTTGTTTTAGATTCCTGCCTAATAAATCATGGTGTTACATGTTGTAACCTACAAAA

Function

symbol description
c3a.3 Predicted to enable endopeptidase inhibitor activity. Predicted to act upstream of or within complement activation. Predicted to be located in extracellular space. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; and sickle cell anemia. Orthologous to human C3 (complement C3).

GO:

id name namespace
GO:0006956 complement activation biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0004866 endopeptidase inhibitor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990415-37 Predicted to enable endopeptidase inhibitor activity. Predicted to act upstream of or within complement activation. Predicted to be located in extracellular space. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; and sickle cell anemia. Orthologous to human C3 (complement C3).

Ensembl:

ensembl_id ENSDARG00000052207

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001257 True 5209 mRNA 0.44 41 56274613 56320569

Neighbor

gene id symbol gene type direction distance location
XLOC_000766 c3a.2 coding upstream 7882 56229674 ~ 56266731 (+)
XLOC_000765 crb3b coding upstream 89685 56180416 ~ 56184928 (+)
XLOC_000764 tecrb coding upstream 497459 55752593 ~ 55777154 (+)
XLOC_000763 adgre10 coding upstream 527610 55730205 ~ 55747003 (+)
XLOC_000762 adgre17 coding upstream 546155 55723870 ~ 55728458 (+)
XLOC_000768 NA coding downstream 96069 56416638 ~ 56556305 (+)
XLOC_000769 CABZ01059392.1 coding downstream 126538 56447107 ~ 56458037 (+)
XLOC_000770 zgc:171452 coding downstream 142925 56463494 ~ 56468601 (+)
XLOC_000771 CABZ01059403.1 coding downstream 182137 56502706 ~ 56529192 (+)
XLOC_000772 NA coding downstream 240657 56561226 ~ 56604352 (+)
XLOC_000760 NA non-coding upstream 545487 55714918 ~ 55729126 (+)
XLOC_000761 NA non-coding upstream 553198 55717578 ~ 55721415 (+)
XLOC_000758 NA non-coding upstream 595166 55678912 ~ 55679447 (+)
XLOC_000748 NA non-coding upstream 835338 55437572 ~ 55439275 (+)
XLOC_000747 NA non-coding upstream 881581 55392380 ~ 55393032 (+)
XLOC_000773 NA non-coding downstream 242258 56562827 ~ 56564352 (+)
XLOC_000774 NA non-coding downstream 248945 56569514 ~ 56603810 (+)
XLOC_000775 NA non-coding downstream 339628 56660197 ~ 56662651 (+)

Expression


Co-expression Network