CI01000013_03493064_03499971 (GOT2, GOT2A, GOT2B)


Basic Information

Item Value
gene id CI01000013_03493064_03499971
gene name GOT2, GOT2A, GOT2B
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000013
NCBI id null
chromosome length 12551977
location 3493064 ~ 3500131 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000013_03493064_03499971.mRNA
ATGGCCCTGCTAAAATCCAGCAAGATTTTGACTAGTGTCGGGGCTCAGGCCCCTGTTTTAGCAGTCTTACAGCTCCGTGCAAGCTCATGGTGGACTGAGGTACAGATGGGACCCCCTGATCCCATCCTGGGTGTCACGGAGGCGTTCAGGCGTGACACCAACCCCAAAAAGATGAACCTCGGAGTAGGAGCTTATAGAGACGATCAGGGCAAGCCGTTTGTCCTCAACTGTGTCCGAAAGGCTGAGGCCCAGATTGCTGCTAAGAAGTTGGATAAAGAGTACCTTCCTATTGTAGGATTGGCAGACTTTTCAAAGGCCTGTGCTCAGCTGGCTCTTGGACCTGATAATGAGGTCTTAAAGAGCGGAAGAAGCATCACTGTCCAGACTATCTCTGGAACTGGATCTCTTCGTGTTGGTGCTAACTTTTTGGCACGATTCCATAATGTGTCCCGGGACGTGTACCTGCCTAAACCCTCCTGGGGAAACCACACCCCTATCTTCAGAGATGCGGGCATGCAGCTAAAGGCTTACACCTACTATGACCCAAAAACCATTGGCTTTGACCTTAAAGGAGCCTTGGATGATATTTCAAAAATCCCTGAAAAGAGTGTGATTGTTCTGCATGCGTGCGCTCATAATCCCACAGGAGTGGACCCAAGGCCCGAGCAGTGGAAAGAGATGGCTGCTCTGATCAAGAAAAGAAACCTCCTGGTCTTCTTTGACATGGCTTACCAGGGATTTGCCAGTGGCGACATCGATCGTGACGCTTGGGCTGTGCGTTATTTCATTGAGCAGGGGCACAACATTCTTCTGTCCCAGTCTTTTGCAAAGAACATGGGCCTGTATGGTGAGCGTGTAGGGGGCTTCACGGTGGTGTGTAAGGATGCTGAAGAGGCGAAACGTGTGGAATCCCAGCTGAAAATTCTCATTCGGCCCATCTACTCCAACCCACCCATGAATGGAGCTCGCATCGCCTCCACTATTCTCAACACACCCGAACTCTACAAAGAATGGCTCGAGGAGGTGAAAGGCATGGCCACCCGTATCATCAGGATGAGGGAGATGCTTGTTTCTAACCTTAAGAAGGAGGGCTCCACTCAGGACTGGCAGCATGTCACTGACCAGATTGGAATGTTCTGCTTCACGGGACTCAAACCGGAACAGGCAAGTCAAGTTAAAGTGGAGCGTCTGATTAAAGAATTCTCTATATACATGACAAAAGATGGCCGGATCTCCATGGCTGGTGTGACATCTGCAAACGTGGAATATCTAGCACACTCCATCCATGCTGTCACCAAGTGAAGCTGACAGCAGACAGAGAGCAAGCAAAAAGTAATTTAGATGATATAAAGTCCTCTGCTGTCTGTCTTTTAGAACCAAATATGAAATAGAACTAATGTAGACTTCTAGTTCACTTGATTTGGCATTATAAATGTTAATTCATGACTATGTGAGCCCCTCA

Function

symbol description
got2b Predicted to enable L-aspartate:2-oxoglutarate aminotransferase activity. Predicted to be involved in aspartate catabolic process. Predicted to act upstream of or within biosynthetic process and cellular amino acid metabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including adaxial cell; cardiovascular system; musculature system; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Orthologous to human GOT2 (glutamic-oxaloacetic transaminase 2).
got2a Predicted to enable L-aspartate:2-oxoglutarate aminotransferase activity. Predicted to be involved in aspartate catabolic process. Predicted to act upstream of or within biosynthetic process and cellular amino acid metabolic process. Predicted to be located in mitochondrial matrix and plasma membrane. Predicted to be active in mitochondrion. Used to study developmental and epileptic encephalopathy 82 and early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Orthologous to human GOT2 (glutamic-oxaloacetic transaminase 2).
got2 Enables L-aspartate:2-oxoglutarate aminotransferase activity. Involved in aspartate catabolic process; fatty acid transport; and response to ethanol. Located in mitochondrion and plasma membrane. Implicated in developmental and epileptic encephalopathy 82.

GO:

id name namespace
GO:0008483 transaminase activity molecular_function

KEGG:

id description
K14455 GOT2; aspartate aminotransferase, mitochondrial

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000013_03493064_03499971.mRNA True 1462 mRNA 0.49 10 3493064 3500131

Neighbor

gene id symbol gene type direction distance location
CI01000013_03477151_03488842 CALB2, CALB2A coding upstream 3731 3477040 ~ 3489333 (+)
CI01000013_03457529_03463949 PNP6 coding upstream 28053 3457529 ~ 3465011 (+)
CI01000013_03262979_03269729 SLC38A8A coding upstream 223182 3262979 ~ 3269882 (+)
CI01000013_03241607_03258684 MBTPS1 coding upstream 233861 3241607 ~ 3259203 (+)
CI01000013_03225714_03236717 FAN1 coding upstream 256019 3225714 ~ 3237045 (+)
CI01000013_03501267_03503856 NA coding downstream 1136 3501267 ~ 3504388 (+)
CI01000013_03505522_03510594 NA coding downstream 5391 3505522 ~ 3510717 (+)
CI01000013_03565240_03566364 NA coding downstream 65005 3565136 ~ 3566551 (+)
CI01000013_03570185_03581155 NA coding downstream 69958 3570089 ~ 3581729 (+)
CI01000013_03617490_03705093 IGF1R, IGF1RA coding downstream 117359 3617490 ~ 3705093 (+)
G80003 NA non-coding upstream 81059 3411495 ~ 3412005 (+)
G79994 NA non-coding upstream 102738 3389945 ~ 3390326 (+)
G79976 NA non-coding upstream 118821 3373928 ~ 3374243 (+)
G79909 NA non-coding upstream 127171 3365542 ~ 3365893 (+)
G79639 NA non-coding upstream 290751 3201911 ~ 3202313 (+)
G80058 NA non-coding downstream 30304 3530435 ~ 3530847 (+)
G80041 NA non-coding downstream 102232 3602363 ~ 3652575 (+)
G80040 NA non-coding downstream 206592 3706723 ~ 3708228 (+)
G80037 NA non-coding downstream 208826 3708957 ~ 3712091 (+)
G80068 NA non-coding downstream 212845 3712976 ~ 3713187 (+)
G79309 NA other upstream 1025893 2466765 ~ 2467171 (+)
G77695 NA other upstream 2540095 946521 ~ 952969 (+)
G77533 NA other upstream 2783515 708833 ~ 709549 (+)
G80062 NA other downstream 83877 3584008 ~ 3584784 (+)
CI01000013_04051081_04064651 NA other downstream 564802 4050837 ~ 4065829 (+)
G80845 NA other downstream 1334947 4835078 ~ 4836232 (+)
CI01000013_06050285_06059640 NA other downstream 2556167 6049864 ~ 6060269 (+)
CI01000013_06076169_06080164 NA other downstream 2578431 6075400 ~ 6081684 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_013405 got2a coding NC_007129.7 CM002902.2 21178721 ~ 21188768 (-)
bowfin (Amia calva) AMCG00020393 got2,got2a,LOC107694944,LOC107596935,LOC107738675,LOC107672286,LOC107726360,LOC107707915 coding CM030127.1 CM030127.1 17917969 ~ 17926416 (+)