CI01000013_03617490_03705093 (IGF1R, IGF1RA)


Basic Information

Item Value
gene id CI01000013_03617490_03705093
gene name IGF1R, IGF1RA
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000013
NCBI id null
chromosome length 12551977
location 3617490 ~ 3705093 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000013_03617490_03705093.mRNA
TGTGGTCCTCACATTGATATCCGCAATGACATCAGTGAGTTCAAGAAGCTGGAGAACTGCACGGTGGTGGAAGGCTACCTGCAGATCCTTCTCATTGGAGACAAGAATAACAACCTCAACCAGGAACACTTTCGCACCCTGTCCTTCCCCAAGCTGACCATGGTCACTGACTACCTTCTCCTGTTTCGTGTCTCCGGCCTGGACAGCCTGAGCATTCTCTTCCCCAACCTCACCGTCATTCGAGGACGCAACCTGTTCTACAACTACGCCCTGGTCATCTTCGAAATGACCAGCCTGAAAGATATTGGTCTCTACAACTTGAGGAACATCACCAGAGGGGCCATCAGAATCGAAAAGAATCCAGAGCTGTGTTACTTGGACTCAGTGGACTGGTCGCTCATTATGGATGCAGAGTTTAACAACTACATCAATGGGAACAAGCAGTCCAAAGAATGCGGTGATGTTTGTCCAGGTATCATGGAGGAGAGTCCGAAGTGTATTAGGACCAGCTTCAATGACAACTACAGCTACCGCTGCTGGACCTCCAGCTACTGCCAGAAGGTGTGTCCAAAGAAGTGTGAGAAGAGGGCATGCACGGATGAGGGCGAGTGCTGTCACCCCCAGTGCCTGGGCAGCTGCACTGAACCAGACGATGATAAGGCATGTGCCGCCTGCCAGCATTACTTTCACGAGGACCGCTGCGTTGAGGCCTGCCCACCGGGCACCTACAAGTTTGAAGGCTGGCGCTGCATCACCATGGACATGTGTGCCCGTGTTCACCTACCCAGTGAGGTCGACTTCGTCATCCACAACGGAGAGTGTATGCCAGAATGCCCGCCCGGATTCACCCGAAATGAGACTCAGAGTATGTTTTGTAGTGCGTGTGACGGACTGTGTGATAAGGTCTGCGAAACTAAAACAATCGACTCAGTGGATGCTGCTCAGTCCCTGCAGGGCTGCACGGTCATCAAAGGCAACCTGCACATCAACATCCGGCGGGGCAATAACATTGCATCAGAGCTGGAGAGTTTCATGGGCCTGATCCAGACAGTCACTGGATATGTAAAGATCAAACACTCTCAGACTCTGGGTTCTCTGTCCTTCCTCAAAAGTCTGCGATACATTAATGGAGAAGAGCTCGCAGATCAGATGTACGCATTCTATGCAGTGGACAACCAGAACTTGCAGTACTTGTGGGACTGGAGTCAGCACAATCTGACCATTAGAACTGGAAAACTCTTCTTCCGCTTCAATCCCAAGCTTTGCATGTCTGAGATCCAGAAAATGTGGGAGAAGACCAGCGTAAAGGAAAAGATGGAAGAGGACGACGTTCGAAGCAATGGAGAGCGAGCAAGTTGTGAGAGTTATATTCTAAAGTTCAAATCCAACCACACTCAGAGTACTCGGATAAAGCTCACTTGGGAGCGATATCGACCGCCTGACTACAGAGACCTCATCAGCTTCATCGTGTATTACAAGGAGGCACCATTCCAGAACATCACAGAATTTGACGGACAAGACGGATGTGGCTCTAATAGCTGGAACATGGTGGATGTGGACCTTCCTCCGGAGAAATCAACCGACCCTGGGGTATTTCTGTCCCCTCTTAAACCTTGGACACAATATGCCATCTTTGTGAAAGCTGTCACCCTGGTTGTGGAGGATAAACATATTCCTGGAGCTAAGAGTGAGGTGGTTTACATCCGCACCAATGCATCAGCGCCATCAATGCCCCTCGATGCCCGCGCATATGCCAACTCCTCCTCATCCCTGATGGTGAAGTGGTCTCCTCCCATCTCTCCCAACGGGAACAAAACATTCTACCTACTCCGTTGGCAGCAGCAGGCAGAAGACCGTGAACTGTATCAGCATAACTACTGCTCTAAAGAGCTAAAGATCCCCATCCGCATCTCAGCCACGGCTTTGACGGACACAGAGGGCGACACAAAGCCTACCAAATCAGATGTTGGCGGGGGTGAGAAGGGCTGCTGCCCCTGCCCAAAAACCAATGAGGACCTAAAGGCGGAAGCTGAAGACCGATCCTACCGCAAAGTCTTCGAGAACTTCCTGCACAACTCCATCTTCACACCCAGACCTCCAGACAGGAAGCGTCGAGACCTGTTCGGAGTGGCCAATGGCACACTCCTCCAAGGTGCAAGCAGGAACATCACAGGACTGGAGAGCAACATCACTGACCCAGAGCTGCTGGAGAAAGAGTATCCTTTCTCCGAAGGCAAAGTCCATACAGAGTTCATGGAGATTTCCAACCTGCAGCCCTTCACTGTGTACCGCATCGACATCCACGCTTGTAACTACAAAGTCCACCGTTGCAGTGCTGCAGCTTTTGTGTTCTCTAGAACCAAACCAGCAGACAAAGCGGATGATATTCCCGGCACTGTAACTCAGGAGAGGGATGAGAAAGCAGAAGGAACAGTGCTGCTGCGGTGGCCTGAACCTCATCACCCTAATGGACTGATCCTCATGTATGAGATCAAATATCGTCTGGGAACTGAGCAAGAGAAGCATGAGTGTGTGTCACGGCAGCAGTACAGAGTGCTGCGCGGAGCTCAACTTAGCAATTTGGCCCCAGGAAATTATTCCGCCCGGGTCAGAGCCACTTCTCTGGCTGGGAATGGGTCTTGGACTGAACCGGTGTCCTTCTATGTGCCACCCCTTAAAAGAAATGATGATAATGCCTTCTATCTGGCCATCATAATCCCTATTATAGTGCTATTGTTGCTCACTGCAGTGATCACCGTTGTCATCTTTGTCACCAAAAAGAGGAATAGTGACCGGTTAGGAAACGGTGTGCTCTATGCTTCTGTAAACCCTGAATATTTCAGCCCTTTTGAAATGTATGTACCAGATGAATGGGAAGTGGCTCGGGAGAAAATCACCATGTGCCGTGAGCTGGGCCAAGGCTCCTTTGGTATGGTGTACGAGGGCATCGCAAAGGGCGTCGTCAAAGACGAACCTGAGACCAGAGTGGCCATCAAGACTGTAAACGAATCCGCCAGTATGCGTGAACGCATCGAGTTCTTGAACGAAGCTTCCGTTATGAAGGAGTTCAACTGTCACCATGTGGTGCGACTTCTGGGTGTGGTTTCACAAGGCCAGCCCACTCTAGTTATAATGGAGCTGATGACACGGGGCGATCTGAAGAGCTACTTGCGTTCTCTCCGTTCGAAAGAGCAGGGCTCTAGCAGCCAGTCTTTGCCTCCGCTGAAGAAGATGATTCAGATGGCTGGAGAGATAGCGGACGGGATGGCATACCTCAATGCCAACAAGTTTGTCCATCGAGACCTGGCTGCCAGGAACTGCATGGTTGCTGAGGACTTCACAGTTAAAATCGGAGACTTTGGCATGACAAGGGATATCTACGAGACCGATTACTATCGCAAAGGAGGCAAAGGGCTGCTGCCGGTCCGCTGGATGTCCCCAGAGTCTTTGAAAGATGGAGTGTTCACAACAAATTCTGATGTCTGGTCATTCGGAGTGGTTTTATGGGAGATTGCCACTTTAGCCGAGCAGCCCTACCAGGGCATGTCCAACGAGCAGGTACTGCGCTTCGTCATGGAGGGAGGACTGCTGGACAAACCGGACAACTGTCCCGACATGCTGTTTGAACTGATGCGGATGTGCTGGCAGTACAACCCTAAAATGCGACCTTCTTTTCTGGAGATCATCAACAGCATAAAAGAGGAACTGGAGCCGCCCTTCCGGGAGGTTAGCTTTTTCTACAGTGAGGAGAACAAGCCCCCCGACACCGAGGAACTGGACATGGAGGTGGAGAACATGGAGAACGTTCCACTGGATCCTGCTTCCACATTGGCCCCCTCCTCTCAGGGGAGCACAGGAGCTCAGACCCAGAGTCCACAACCGCTCTCCCCAGCTCAGGGGCCTGGGACACCAATGGGGTCCGCCCTAACCCCCTCCACCTCACCGCCTTCCTCCTCAGCCTCTCCAGGCCTGGCCTTAGACATGCACTCAGGACAGGTAGCAGCAAACGGGCCAGTGGTGCTGCTGGGGCCGGCGTTCGATGAGACGCAGCCCTACGCACACATGAACGGGGGGAGGAAGAACGAGCGAGTGCTGCCACTGCCTCAATCATCGGCCTGC

Function

symbol description
igf1ra Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process and insulin-like growth factor binding activity. Acts upstream of or within several processes, including animal organ development; fin regeneration; and insulin-like growth factor receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be part of insulin receptor complex. Predicted to be active in axon. Predicted to be integral component of plasma membrane. Is expressed in several structures, including digestive system; eye; gill; musculature system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple); kidney cancer (multiple); liver disease (multiple); nervous system cancer (multiple); and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor).
igf1r Enables several functions, including insulin binding activity; insulin receptor binding activity; and insulin receptor substrate binding activity. Involved in several processes, including cellular response to amyloid-beta; insulin-like growth factor receptor signaling pathway; and regulation of MAPK cascade. Acts upstream of or within peptidyl-tyrosine autophosphorylation. Located in intracellular membrane-bounded organelle and membrane. Part of alphav-beta3 integrin-IGF-1-IGF1R complex; protein kinase complex; and receptor complex. Implicated in several diseases, including IgA glomerulonephritis; dementia (multiple); kidney cancer (multiple); liver disease (multiple); and nervous system cancer (multiple). Biomarker of several diseases, including Kuhnt-Junius degeneration; autoimmune disease (multiple); endocrine gland cancer (multiple); neurodegenerative disease (multiple); and prostate disease (multiple).

GO:

id name namespace
GO:0048752 semicircular canal morphogenesis biological_process

KEGG:

id description
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000013_03617490_03705093.mRNA True 4119 mRNA 0.52 20 3617490 3705093

Neighbor

gene id symbol gene type direction distance location
CI01000013_03570185_03581155 NA coding upstream 35761 3570089 ~ 3581729 (+)
CI01000013_03565240_03566364 NA coding upstream 50939 3565136 ~ 3566551 (+)
CI01000013_03505522_03510594 NA coding upstream 106773 3505522 ~ 3510717 (+)
CI01000013_03501267_03503856 NA coding upstream 113102 3501267 ~ 3504388 (+)
CI01000013_03493064_03499971 GOT2, GOT2A, GOT2B coding upstream 117359 3493064 ~ 3500131 (+)
CI01000013_03715150_03721616 SYNM coding downstream 10057 3715150 ~ 3721731 (+)
CI01000013_03744519_03787129 CTTNBP2 coding downstream 39426 3744519 ~ 3788177 (+)
CI01000013_03823326_03839656 ASZ1 coding downstream 118233 3823326 ~ 3839910 (+)
CI01000013_03843207_03852634 WNT2 coding downstream 138114 3843207 ~ 3854025 (+)
CI01000013_03856173_03872356 BCL2L13 coding downstream 151080 3856173 ~ 3872947 (+)
G80058 NA non-coding upstream 86643 3530435 ~ 3530847 (+)
G80003 NA non-coding upstream 205485 3411495 ~ 3412005 (+)
G79994 NA non-coding upstream 227164 3389945 ~ 3390326 (+)
G79976 NA non-coding upstream 243247 3373928 ~ 3374243 (+)
G79909 NA non-coding upstream 251597 3365542 ~ 3365893 (+)
G80040 NA non-coding downstream 1630 3706723 ~ 3708228 (+)
G80037 NA non-coding downstream 3864 3708957 ~ 3712091 (+)
G80068 NA non-coding downstream 7883 3712976 ~ 3713187 (+)
G80069 NA non-coding downstream 8204 3713297 ~ 3713517 (+)
G80072 NA non-coding downstream 27050 3732143 ~ 3740009 (+)
G80062 NA other upstream 32706 3584008 ~ 3584784 (+)
G79309 NA other upstream 1150319 2466765 ~ 2467171 (+)
G77695 NA other upstream 2664521 946521 ~ 952969 (+)
G77533 NA other upstream 2907941 708833 ~ 709549 (+)
CI01000013_04051081_04064651 NA other downstream 359840 4050837 ~ 4065829 (+)
G80845 NA other downstream 1129985 4835078 ~ 4836232 (+)
CI01000013_06050285_06059640 NA other downstream 2351205 6049864 ~ 6060269 (+)
CI01000013_06076169_06080164 NA other downstream 2373469 6075400 ~ 6081684 (+)
G81994 NA other downstream 3630852 7335945 ~ 7338239 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location