G58031 (mthfr,LOC107687111)


Basic Information

Item Value
gene id G58031
gene name mthfr,LOC107687111
gene type non-coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035902.1
NCBI id CM008305.1
chromosome length 52532229
location 41449213 ~ 41452982 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>TU78249
TAACTTTAACcagttcctctttttttttttttttttttaaccatttgaggctaaattaattttcagatttatttatttttttgccccCAATTTGATAGTATAATCCATCCACCTTTCATTACATGATGcaaaaatgagaagaaaaaaaaatgaaataagagTAAAGATTAATTAATTCAGACTTTGGGGGCagatatgaacaaaaaaaatggaaaaaaaaaaaaaaacatggaaaatggaaaaacatTACACTGACGGAAATATGACCCAAGGCAATGATAAAACAACCTTCTTCAGATTACAATAGTAATCAAAAATCTCCGTCACCATCTTTGGCCTTGGATGACTTCACTAGTAAATATTTGTGCGTTAAGCTTCTGAccggtctttttttttttttttaactctgcaAGGTTGCAgttttgtgtgggtgtgtgtgcgtgtgtttgtgtgatgtaGCTGGCGAGATAAAAAGCAGAAagtccccccaaaaaaacttgacatCCTCGGACTTCGGACTCGCGCAACAGccaaaatactgtttataaatagctttaaaaacatcagcttaaaaaattacataaaaatgtagaaatagTAATCCTTGCAAATCCTTGTGCCATTGATTCCAGGAATTAGACTGTACATGATAATGTACTATGATTCCCTATAATATCTGTATATTTGTCTAATAATGTGTTAAAAGTGCTCTTGCCCTTGATTTGCAATAATCATAAGTTAGAAGCTTTCGATTCTGTAAACTGTTCTGAAAATTCATCAGCATTTTTATGTAGCATTTTATGTAACAACTCAGACGAGTGAGAGTATAAATAGCtgatattacaataataaaaaaaaaattaatagtgATATGTCTCTGTTTGTGTCTTTATAATAAGTCCTAGaataaagcagcagcagaccAAAGGTGTGTGGTTTTTGAAGCTACTGTAGGTTTTCTTGATCCAGAGGTTCTGGAGGTGCGTCCAGCAGTTCGAACATGTCGTCGATGACCTGCCATAAGCAGCTATCTAGAGGGAAGTCATTGTCCACTAGGTTGACCAGGAAGTAATTGTCGTGGATGTACTGGATAATCATTCGTGAAGGAGACTCGTCCTCGTAAAGCTTCCCCCACTGCTCGATCCACAGTGCGAACGCCTCGTCCTTCCAGTACATAAAGCTGACTGGATCCACCACCGTGGGCTGAACAATCTCTTTGCCTGGGAAAATCCCCCACGTTACAGCATTGGGTTGCATATCATGGGCGTTTGTAATATTCTTGCCCTTCACATTGACAATGTGGTAGTTCACACGTGGTTCATATTTCTTCAGTACTTGGAGAAGTGCGTTAACATTTTCACTTGATGTGAAGAATTCCAGGTATGACTTTTGAAAGACATATCCGCCCGGTGGGCCCCACCCCACAATTGGGTCAGAAGAAGGCTTGCCATTGATGTTGGGCTGAGAGTTGATGGTGAGAACTCCCCTGCGATTCACCTTCTCCAGTTCCTCCTTCAGCATGTTTGTCTCTGGAGCTAAAGGGTCATCGTTCCATGGAAGACACATCACCTTGTGTCCACTCTTGTTGGGCTCTGCTGTGATGTAGTTAGTGAAGACTTGATACACACTGTCCTCACTGGTTAGCTCCTCTTCCCACATCTTCAATAAGGCCTCTTTGGAAGACTTGCTCTTCAGGTAGAACAAATAATAATCTGTCAGCTCGCCAAAAGCTGGGGATGAGGAGTTTCCcctaagaaagaaaataaactgaGTTTAATGTGCAAGATTTCAGCTTCAGTAGAAATTTTCTTTAACAGTAATTTTACACATAAGCCCCTTTATTTGAGGAGACTTCTCCTTAGCCAACGGCATTCTGATTAAAGGAGAAATTGCATGTGAAATGTTTTTTGGATGTAGTGAAACGTGATAATGAGTttgaacttttgtcaaatagcccatcTCCATTcgcccccagcattctgaaatacagtgcttttagccgatgctcccaataGGCTTACCATGCTattgataggggcatagtgttgcccatttaaataatttttttttttttacaccattaaccaTTTTTACACCAAGCTCGatgtagctccacacttcacggATAGAATTCAGAGGCCctgacttttaaaataaagcacTGAGAATTTGAAACaaaggtagtttattaaaaaagactatttatacacacagtaccttcaggtagttctTTGGGTGTCcccatcttgaaattaaatcAC

Function

symbol description
mthfr Predicted to enable FAD binding activity and methylenetetrahydrofolate reductase (NAD(P)H) activity. Predicted to be involved in methionine biosynthetic process and tetrahydrofolate interconversion. Predicted to act upstream of or within methionine metabolic process. Predicted to be active in cytosol. Is expressed in anterior neural tube; optic cup; and somite. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); and kidney failure (multiple). Orthologous to human MTHFR (methylenetetrahydrofolate reductase).

NR:

description
PREDICTED: methylenetetrahydrofolate reductase

GO: NA

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
TU78249 True 2261 lncRNA 0.39 5 41449213 41452982

Neighbor

gene id symbol gene type direction distance location
clcn6 clcn6 coding downstream 12735 41405371 ~ 41436478 (-)
plod1 plod1,plod1a,LOC107698842 coding downstream 152520 41281161 ~ 41296693 (-)
mfn2 mfn2,LOC107748965,LOC107710790,LOC107602467,LOC107678429 coding downstream 170735 41247386 ~ 41278478 (-)
prdm16 prdm16 coding downstream 376974 40763855 ~ 41072239 (-)
tp73 tp73 coding downstream 722734 40666471 ~ 40726479 (-)
LOC103033502 NA coding upstream 5014 41457996 ~ 41493671 (-)
LOC103034037 NA coding upstream 40622 41493604 ~ 41513087 (-)
pex10 pex10 coding upstream 63983 41516965 ~ 41527890 (-)
LOC103035734 NA coding upstream 526575 41979557 ~ 42034244 (-)
LOC103037059 gpr153,LOC107687122,LOC107693426 coding upstream 634406 42087388 ~ 42177716 (-)
G57920 NA non-coding downstream 687041 40761495 ~ 40762172 (-)
G57925 wrap73,LOC107678416,LOC107748967,LOC107710786,LOC107595759 non-coding downstream 700674 40741514 ~ 40748539 (-)
G57916 NA non-coding downstream 784449 40664520 ~ 40664764 (-)
G57788 NA non-coding downstream 1158027 40290977 ~ 40291186 (-)
G57782 NA non-coding downstream 1193397 40255567 ~ 40255816 (-)
G58145 NA non-coding upstream 399607 41852589 ~ 41944829 (-)
G58152 NA non-coding upstream 423281 41876263 ~ 41934574 (-)
G58149 plch2 non-coding upstream 447128 41900110 ~ 41903678 (-)
G58159 NA non-coding upstream 457801 41910783 ~ 41911110 (-)
G58185 NA non-coding upstream 598968 42051950 ~ 42052535 (-)
G58022 LOC103032860,LOC108432146 other downstream 50735 41396086 ~ 41398478 (-)
tprg1l tprg1l,LOC107710788,LOC107678419,LOC107698845,LOC106513028 other downstream 693199 40748741 ~ 40756014 (-)
LOC103037008 LOC108442081,LOC105022382,LOC106567250 other downstream 1270072 40165400 ~ 40179141 (-)
G57727 kdm5c,LOC107550909,LOC107747206,LOC107570512 other downstream 1330118 40117789 ~ 40119095 (-)
LOC103030299 fkbp1aa,fkb1b,fkbp1a,LOC103030299,LOC107553142,LOC107574256,LOC107752559,LOC107707744 other downstream 1886292 39521544 ~ 39562921 (-)
G58435 aaas other upstream 1649888 43102870 ~ 43107623 (-)
G58537 NA other upstream 2229342 43682324 ~ 43682684 (-)
G58649 NA other upstream 2914918 44367900 ~ 44368368 (-)
G58678 NA other upstream 3021177 44474159 ~ 44477666 (-)
snrnp200 snrnp200,LOC107686403,LOC107602857,LOC107667532,LOC107600001,LOC108265067 other upstream 3133324 44586306 ~ 44622074 (-)

Expression


Co-expression Network