nras (nras,LOC107598969,LOC107725308)



Basic Information


Item Value
gene id nras
gene name nras,LOC107598969,LOC107725308
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035902.1
NCBI id CM008305.1
chromosome length 52532229
location 37117419 ~ 37126020 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007228897.3
TGGCCGGTTTGCCGCAGAGCCCCGAGAGACAGAAGCAGAGAGAGCAGCTGAATTATCTAATAGGAAGCTCAACCTTGCTTTAGGAACTCCTGCTGAAACCAGAACAGACAGATCTCAGCTCTACAGCACTTTAGAACAGGATACCGGCTCCCTGCTGCTTCATTTTACCCCGGTAAAGAAGCGGAGTGCTGTTAGATAGAGTCCAGAATGGCGAGTTATACAGACCGCAACTGCTAAAGCAGCAACACCAGCCggggagacggagagagagagggaggtagagagagagaccgaggaCTGCGGACTCTAGTGGTGAGCCAGGGGCAGCTGCAGGATGACTGAATACAagctggtggtggtgggagCTGGTGGCGTTGGGAAGAGTGCACTGACGATCCAGCTGATCCAGAATCACTTCGTGGACGAATATGACCCCACCATAGAGGACTCGTACAGGAAGCAGGTGGTGATCGATGGGGAGACGTGTCTACTGGACATCCTGGACACAGCAGGCCAAGAGGAGTACAGTGCTATGAGGGATCAGTACATGAGGACTGGAGAGGGCTTTCTCTGTGTCTTCGCCATCAACAACACCAAGTCCTTCGCTGATGTGCATCTGTATAGGGAGCAGATTAAGCGGGTGAAGGACTCTGATGATGTGCCGATGGTGCTGGTGGGAAACAAATGTGATTTGGCCAGAACTGTTGACACCAAGCAGGCCCAGGAACTAGCCAGGAGCTACGGCATAGAATTTGTAGAAACTTCAGCCAAGACCCGACAGGGAGTTGAAGACGCTTTTTACACCCTTGTTCGGGAGATCCGCCATTATCGCATGAAAAAGCTCAACAGCAGGGAGGACAGGAAGCAGGGCTGCCTCGGCGTCTCCTGTGAGGTCATGTGATCAGGACGTGCGCCACCCCCCTCCAGAACCCCCTCAGAAGCCCACCGGCCAGCAGCTGAACACTTACGACTTACGCTTGTGACTGAAGAGCTTCTCTGATTGGTTAAGATTTTGCTTCAGCTTTAAATCACAGTAGCCTGAATTCGGCCGGGTCGTGGAGTTTCTGCGGTGTTGCCCTCTGCTGGCTAAAAGGGATAAATGCGAAGCCTGGCctgctggctgtgtgtgtgtgtgtgtgtgtgtgtgtgtggactgtaTCGGCTGCTGTGATGGAAACGTGGGGCCTTATATGTGGGACGTTTTGGCTCCTCTGATCATTTTCACAGACGTGCATTTATCTCTTTAGTCATTAAGTGCTGGGATCTCGCATCTTCCCTTGTTTTTCGGATTTCTCATCGGACTTGATCTTAATCTGTAGGTTCAGTACTCAGGAATACTGTGAAGGTAAAAGTGCCTCTAATGCATCTAATGCGTCTTTAATgcgtttttgttttaatgtagttcttttgtttgtttgttttttaaggtAGACCTATTTGACCTCAGATTGTCTGTCACCGgtttcttttacatttcagCTTGATTCGTgtagatgttttgttttttgggcaTGCAAAATTTAGGAATTTAAGGCTAAAAAATAACCTACAGTAAATGAATGAGAATCGATCGCCTTTACATACATGCTCTTAGAAAACGAGACGAAACTCGTGCACCAGAACCTCCAAGAACCAATtcttaatgcttaagaatgctTAATGAAATTTGTGTGCCTAATTATTTCAAATACGTTCATAAAAAGGAGAAATGTGCCTTTTTTAGTTAGATAAATGACATCTCTTGTTTTTAGCCAGTAGTGGGAGTCTGGAGTTCAGTAATGCTCAGAAACAATCGATGAGATGCATGAATTAAGGACTGTGAAAAAACTGTAGTCATCTGCACTCTGtgaccttttgtttttttaatgtctgtGCTAAAACGTGCCCAATAGTGTAAAGTGTGCACTGCCTTTAGAAGAATCACCTGGGccaactttattattttttttaaggttttaaagtttagttttgttataaatctgtgttttttatgtttgtttttaacagTGCCTGATTTTACATATAGTTTGTCATAAGTGATGTCAGAAGTGGCTTTATATTAATAgattatctatctatatatctatagatCTGTCAGTCGTTTTTTGCCTGGTGCTACCGTAATTATTAATGTCcctcaaaaaaaataacagttctACAAAACGCAACCACCCACACttgttaaaattgttaaatacagctctggaaaaaa

Function


symbol description
nras Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in Golgi membrane. Predicted to be active in plasma membrane. Is expressed in brain; heart; liver; pleuroperitoneal region; and trunk musculature. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 6; autoimmune lymphoproliferative syndrome type 4; endocrine gland cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human NRAS (NRAS proto-oncogene, GTPase).

NR:

description
GTPase NRas

GO:

id name namespace
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0006184 obsolete GTP catabolic process biological_process
GO:0000139 Golgi membrane cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005525 GTP binding molecular_function

KEGG:

id description
K07828 NRAS; GTPase NRas

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007228897.3 True 2212 mRNA 0.45 5 37117419 37126020

Neighbor


gene id symbol gene type direction distance location
LOC103040231 asb13,asb13b,LOC108266053,LOC107734516,LOC107725307,LOC107599049,LOC107664994 coding upstream 2011 37111541 ~ 37115408 (+)
LOC103044321 plekha2,LOC108414546 coding upstream 6625 37094714 ~ 37110794 (+)
LOC111192679 NA coding upstream 26032 37086442 ~ 37091387 (+)
LOC103040549 NA coding upstream 31920 37064399 ~ 37085499 (+)
endog endog,LOC107736532 coding upstream 518523 36596016 ~ 36598896 (+)
ampd1 ampd1,LOC107664993 coding downstream 915 37126935 ~ 37150039 (+)
LOC103044036 dennd2c,LOC108438557,LOC107566809,LOC107725285 coding downstream 25229 37151249 ~ 37182523 (+)
bcas2 bcas2,LOC107674303,LOC107734517,LOC107664982,LOC107725297 coding downstream 58399 37184419 ~ 37188716 (+)
trim33 trim33,LOC107734526,LOC107725313 coding downstream 65978 37191998 ~ 37237659 (+)
pqlc2 pqlc2 coding downstream 114654 37240674 ~ 37250970 (+)
G56859 NA non-coding upstream 242072 36807703 ~ 36875347 (+)
G56863 NA non-coding upstream 284373 36825767 ~ 36833046 (+)
G56862 NA non-coding upstream 287929 36827530 ~ 36829490 (+)
G56853 NA non-coding upstream 344548 36770816 ~ 36772871 (+)
G56852 NA non-coding upstream 365778 36749089 ~ 36751641 (+)
G57088 NA non-coding downstream 104970 37230990 ~ 37233036 (+)
G57209 NA non-coding downstream 262069 37388089 ~ 37391366 (+)
G57212 NA non-coding downstream 347976 37473996 ~ 37474778 (+)
G57227 NA non-coding downstream 351212 37477232 ~ 37548787 (+)
G57229 NA non-coding downstream 360351 37486371 ~ 37546259 (+)
G57066 NA other upstream 111621 37005273 ~ 37005798 (+)
G56701 pola2,LOC107710902,LOC107657899 other upstream 1152909 35956104 ~ 35964510 (+)
G56504 NA other upstream 1658542 35420718 ~ 35458877 (+)
LOC103032256 dynll1,LOC103397138,LOC107554284,LOC107559583,LOC100698873 other upstream 1833148 35276079 ~ 35284271 (+)
ikbkb ikbkb,vdac3,LOC107560056,LOC107671013,LOC107754399 other upstream 1844891 35226485 ~ 35272528 (+)
agtpbp1 agtpbp1 other downstream 1983224 39109244 ~ 39153476 (+)
frmd3 frmd3,LOC107678471 other downstream 2166051 39292071 ~ 39370585 (+)
LOC103039219 iqsec2,LOC107747221,LOC107683900,LOC107702804,LOC108265842 other downstream 2841070 39967090 ~ 40090271 (+)
G57664 NA other downstream 2918633 40044653 ~ 40046467 (+)
G57856 tp73 other downstream 3549020 40675040 ~ 40680555 (+)

Expression



Co-expression Network