LOC103041348 (foxe3,foxe1,LOC103041348,LOC103130754)


Basic Information

Item Value
gene id LOC103041348
gene name foxe3,foxe1,LOC103041348,LOC103130754
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035902.1
NCBI id CM008305.1
chromosome length 52532229
location 12118913 ~ 12121673 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007245866.3
GCTtgcatacacaacacacacacacccctcataAGAGCTGACAGGGACCACCACCTCCCACCTCCCTCTCACACACTTGTTgcttgttgctgttgttgtccTCGTGCCCTCTAAAAGTGTCTAAACTCCACTTTTTATGAATCTGGCGAGTTTCTCCTTCTTCTCCGGAGCGTGCAGCATGACCGCGGAGGCGCAGCTCTCTCCGGCCGAGGCTGCGAGCCCCAGCGCCGGCCTGGGCTCTCCGCTCGCCCCGCCCTCCCTCATCCTCATGCACGAGGAGCCAGGGGTCAAGGCCGTCAGCCCGGTTACCGAAGAAGGGGACCGGGACAGTCCCAGGGAGAGCCCGGTGGGTCAGAACggtcagcagcagctgcagaccaCCGAGGAGGATCGCGTGTCCCTCGCGCCCACAGCCGGGGGGCGCCGCCGCAAGCGTCCCGTGCAGCGCGGGAAGCCTCCGTACTCCTACATTGCGCTGATCGCCATGGCCATTGCGCACGCTCCGGAGCGCAGGCTCACGCTGGGGGGCATCTACCGCTTCATCACGGAGCGCTTCCCGTTCTACCGGGAGAACTCCAAGAAGTGGCAGAACTCCATCCGCCACAACCTCACTCTCAACGACTGCTTCGTGAAGATCCCGCGTGAGCCCGGCAGGCCTGGTAAAGGAAACTACTGGACGCTGGACCCCGCGGCCGAGGACATGTTCGACAACGGCAGCTTCCTACGGCGCCGCAAACGCTTTAAGCGCGCGGACGCGAGCGCGTCCTACGCCGCAGCCGCGGCCGCTGTCACCGGCGCGCACGCATATCATCACCACCATCCCGTGCATCACGCGCAGcaccaccaccatctccatcatcaccatcaccactcCTCCGTGCACTCGCACCACGCGCTGTACCCGAGTTACGGCTCACAGGTGCTCCAGCCTCATCACCATCCGCATCCTCATCCTCACCACGCGCCTCACCATCAGTACCATTCCAGGACGTTCACCATAGATGACAtcatcagccaacagatgcccGAGATCAACGTGCACACGCACCCCGTGCACACGCACTGTCTCGGCTTGGGAGGGGAGTTAAGCGCAAGCGTGAGCGCGGTGGAGCAACAGAGTTCCGTGAGCTTTGCAGGCCCTCAGACCATCAACGCAGTGAGCGTGAGCGCGAGTGTAAGCGCCAGCGCGCCGCTGGGCAGGAGCTCCGCGCCCGGTTTTTCGTACCCGTGCGCCCCGGTATCTTCGGTGTCCGCGTCGGTGTCGGTGTCCGCGTCGCAGGCCTCGCCGCAGCCGCCTGCTTTCTCTCCGCCGCCAGCAGGAGGCACCGCAGCGCAGCTGTACTGCGGCAAGCACGCCGAGCCCTCCGTGACAACATACGGAGGAGGTGCCTACACCGCGCGCCAGGGAAGTTACAGCAGCGGGCTCGAGCGGTATATGTGAAATggacacatgcacaaacacatcaCACTCTAAaacaactgaactgaactgacgTGATTCAAATGTGATCAAATCAAACTATTCCAAAATGAAGAAGGCACCACAATAATATGGTGTGGTGTTTAAAGGTTTTGAACCTATGATCTCTGTGGTCTCTTGACATGCAGGCAGTTAGACAGTAGGGCCAAGCTAGAGGTCTTAATGTAAAGCCTTGAGCaagtatgtgtaaaaaaaacgaATGGAAAGACTATTGCATTCAGAACTGTGTTTTAATGCAGcataattttacagctctagacCGGCCCTACAATCTAAGGGCTGTTCATAAAGTGTAAGATGATCATCAGCTCAAATCCCAGTAAGAGCTCTTCAAGTAAGAGTTCTACTGTCAAAAGCTTCTTAGTCTTGTctctttaaattttatttttattctattttacttATGTGGGAATGATGTTTACATTTGAATCaagtcatttttatatatttttatattcatacaaATCAGTCACAGTTCCTGACTTTCTGTTTCTTGCATTTAAAGCATCTGAACCTAATGGTTAcctaatatgtttaatatgttataaacatattattttaacactatGTATACAGCACTGCAGTAGAAGTCACATCCTCCACAGAAATACACTTTTGCACTTTCTAAAATATTGTTAAGGATTAGTTACTGAATTTAGCTTATTAAGTATAACtcacacacataaaaagtaaagtaagcgtgcaaaaaataccaaaacttAATTGGTttagaatttatttaatttcacttAGACCATCAACAAAATGATCAGGGACACCCTAACCATTACAAAAGATTGTATATACTTTGCTTTGGGAAccaaaattaaatgtaacaaactgtAGAATCActaaatttaacatatttaatatactattatttttttcccaattcaCTCTAATGCCAAATTAGTACATTAGTGTCTATGTAGAGGATGTGACgttcacatatatacacacaattcTATTACAATACTATGTATATATCTTCAAAGcatattactgtaatattcaTATACACCAGAATGAAAGAGCGGTTATAACAGCGATCTTGCTGAAACTTAAACTCATATTTCAGTACTTTCAGTTTAAAACCTTAAATTTCATTCTGGGCGTCAGTTTGTTTCCTGTTATCTTTTCACATGTTAATTTATACCTGTATTATATCTGTATCTCTACTGGCCGGTGGTGATGaggctgtatatatttattttggctAATCTGTTTGGTTGTTGTTGAATGTAGTCTGGAAACACTGCTgtagcatttttatattttata

Function

symbol description
foxe1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic viscerocranium morphogenesis and growth plate cartilage chondrocyte proliferation. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; endocrine system; head; notochord; and pharynx. Human ortholog(s) of this gene implicated in Bamforth-Lazarus syndrome and thyroid gland papillary carcinoma. Orthologous to human FOXE1 (forkhead box E1).
foxe3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within aorta development; lens morphogenesis in camera-type eye; and negative regulation of lens fiber cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including adenohypophyseal placode; hatching gland; lens; lens placode; and optic primordium. Human ortholog(s) of this gene implicated in anterior segment dysgenesis; anterior segment dysgenesis 2; cataract 34 multiple types; and thoracic aortic aneurysm. Orthologous to human FOXE3 (forkhead box E3).

NR:

description
forkhead box protein E4-like

GO:

id name namespace
GO:0009888 tissue development biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0048562 embryonic organ morphogenesis biological_process
GO:0002089 lens morphogenesis in camera-type eye biological_process
GO:0007389 pattern specification process biological_process
GO:0030878 thyroid gland development biological_process
GO:0060022 hard palate development biological_process
GO:0060023 soft palate development biological_process
GO:0051090 regulation of DNA-binding transcription factor activity biological_process
GO:0006590 thyroid hormone generation biological_process
GO:0005667 transcription regulator complex cellular_component
GO:0008134 transcription factor binding molecular_function
GO:0003690 double-stranded DNA binding molecular_function
GO:0008301 DNA binding, bending molecular_function

KEGG:

id description
K09398 FOXE; forkhead box protein E

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007245866.3 True 2761 mRNA 0.49 1 12118913 12121673

Neighbor

gene id symbol gene type direction distance location
LOC103041649 slc35a3,LOC108439387,LOC107717552,LOC107585865 coding upstream 26690 12073631 ~ 12092223 (+)
LOC103041950 LOC108439388 coding upstream 53786 11965590 ~ 12065127 (+)
LOC103023153 sec22b,sec22bb,LOC108439390,LOC107548814,LOC107750823,LOC101168279,LOC100705437,LOC107676649 coding upstream 183777 11929298 ~ 11935136 (+)
npl npl coding upstream 197749 11911168 ~ 11921164 (+)
LOC103043198 grm6a,LOC108439669,LOC107601768,LOC107674373,LOC107653428,LOC107743101,LOC106566502 coding upstream 419950 11589324 ~ 11698963 (+)
LOC103047368 fcho1,LOC108442339,LOC107548880,LOC107717548,LOC107676711 coding downstream 329747 12451420 ~ 12538729 (+)
acsbg2 acsbg2,LOC107731199,LOC107676759 coding downstream 483592 12605265 ~ 12644596 (+)
LOC103044019 LOC108439652,LOC108264986,LOC106584369,LOC107585931 coding downstream 725392 12847065 ~ 12876713 (+)
LOC103040421 mob3a,LOC108439653,LOC103368804,LOC100699828,LOC104921817,LOC102783145,LOC104944351,LOC103137270 coding downstream 756963 12878636 ~ 12894487 (+)
mknk2 mknk2,mknk2b,LOC107695256,LOC107585877,LOC107731184 coding downstream 785573 12907246 ~ 12932059 (+)
G51493 NA non-coding upstream 47016 12069418 ~ 12071897 (+)
G51494 NA non-coding upstream 112821 12003020 ~ 12006092 (+)
G51427 NA non-coding upstream 190159 11901883 ~ 11928754 (+)
G51428 NA non-coding upstream 232434 11884009 ~ 11886479 (+)
G51429 NA non-coding upstream 235020 11883467 ~ 11883893 (+)
G51556 NA non-coding downstream 55101 12176774 ~ 12176989 (+)
G51558 NA non-coding downstream 62106 12183779 ~ 12183979 (+)
G51569 NA non-coding downstream 275930 12397603 ~ 12447640 (+)
G51580 NA non-coding downstream 342295 12463968 ~ 12545418 (+)
G51581 NA non-coding downstream 392712 12514385 ~ 12515605 (+)
G51423 cunh1orf21,zgc:92140,LOC107676598,LOC107585858,LOC107750760,LOC107700167,LOC107548740 other upstream 236892 11832681 ~ 11882021 (+)
LOC103038184 acsl2,LOC107553163,LOC107710839,LOC107665192,LOC107716609,LOC108426687,LOC107678403 other upstream 1361658 10687885 ~ 10757255 (+)
nfu1 nfu1,LOC108265347,LOC107553147,LOC105890045 other upstream 1988112 10123720 ~ 10130801 (+)
G50889 grid2,LOC107556295 other upstream 2336192 9643374 ~ 9782721 (+)
G50583 LOC108437602,LOC103398889 other upstream 3774399 8342940 ~ 8344514 (+)
znf692 znf692,LOC108442337,LOC107750903,LOC107695246,LOC106613837 other downstream 315731 12437404 ~ 12448516 (+)
G51743 dohh,LOC107745802,LOC107695215,LOC107585881,LOC107548993 other downstream 1194066 13315739 ~ 13327325 (+)
G51745 NA other downstream 1235052 13356725 ~ 13368274 (+)
LOC103034181 prrg1,LOC108444325,LOC107585847,LOC107657931,LOC107700656,LOC107750596 other downstream 2047771 14169444 ~ 14201302 (+)
G52110 sh3gl1,sh3gl1b other downstream 2184941 14306614 ~ 14324917 (+)

Expression


Co-expression Network