Item | Value |
---|---|
gene id | tp73 |
gene name | tp73 |
gene type | coding |
species | mexican tetra (Astyanax mexicanus) |
category of species | ornamental fish |
Item | Value |
---|---|
chromosome id | NC_035902.1 |
NCBI id | CM008305.1 |
chromosome length | 52532229 |
location | 40666471 ~ 40726479 (-) |
genome version | Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome |
symbol | description |
---|---|
tp73 | Enables DNA-binding transcription factor activity. Acts upstream of or within embryonic cranial skeleton morphogenesis and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including gonad; musculature system; nervous system; pharynx; and renal system. Human ortholog(s) of this gene implicated in breast cancer; lung cancer; nephroblastoma; and renal cell carcinoma. Orthologous to human TP73 (tumor protein p73). |
description |
---|
tumor protein p73 isoform X2 |
id | name | namespace |
---|---|---|
GO:0010332 | response to gamma radiation | biological_process |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological_process |
GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological_process |
GO:0031571 | mitotic G1 DNA damage checkpoint | biological_process |
GO:0000122 | negative regulation of transcription by RNA polymerase II | biological_process |
GO:0010165 | response to X-ray | biological_process |
GO:0051262 | protein tetramerization | biological_process |
GO:0034644 | cellular response to UV | biological_process |
GO:0043508 | negative regulation of JUN kinase activity | biological_process |
GO:0048701 | embryonic cranial skeleton morphogenesis | biological_process |
GO:0043524 | negative regulation of neuron apoptotic process | biological_process |
GO:0000785 | chromatin | cellular_component |
GO:0005829 | cytosol | cellular_component |
GO:0005634 | nucleus | cellular_component |
GO:0005667 | transcription regulator complex | cellular_component |
GO:0043565 | sequence-specific DNA binding | molecular_function |
GO:0002039 | p53 binding | molecular_function |
GO:0003682 | chromatin binding | molecular_function |
GO:0003684 | damaged DNA binding | molecular_function |
GO:0003690 | double-stranded DNA binding | molecular_function |
GO:0003700 | DNA-binding transcription factor activity | molecular_function |
id | description |
---|---|
K10148 | TP73; tumor protein p73 |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
XM_007247904.3 | True | 4597 | mRNA | 0.43 | 14 | 40666471 | 40720152 |
XM_015605500.2 | False | 4364 | mRNA | 0.43 | 12 | 40666471 | 40710275 |
XM_015605501.2 | False | 1933 | mRNA | 0.54 | 14 | 40669137 | 40726477 |
XM_022670685.1 | False | 4555 | mRNA | 0.43 | 14 | 40666471 | 40726479 |
XM_022670686.1 | False | 4405 | mRNA | 0.43 | 12 | 40666471 | 40702612 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
rer1 | rer1,LOC107678415,LOC107710784,LOC107698848,LOC107595758 | coding | downstream | 3900 | 40652574 ~ 40662571 (-) |
LOC103024844 | NA | coding | downstream | 27698 | 40632068 ~ 40638773 (-) |
LOC103026801 | LOC103026801,LOC108414620,LOC107756851,LOC107702881,LOC107573971,LOC107691553,LOC107566963,LOC108265407 | coding | downstream | 38820 | 40619650 ~ 40627651 (-) |
LOC103026522 | eif2s2,LOC103026522,LOC108414623,LOC107739644,LOC107756850,LOC107566961,LOC107666094 | coding | downstream | 50826 | 40609610 ~ 40615645 (-) |
trnaw-cca_41 | NA | coding | downstream | 60371 | 40606029 ~ 40606100 (-) |
prdm16 | prdm16 | coding | upstream | 37376 | 40763855 ~ 41072239 (-) |
mfn2 | mfn2,LOC107748965,LOC107710790,LOC107602467,LOC107678429 | coding | upstream | 520907 | 41247386 ~ 41278478 (-) |
plod1 | plod1,plod1a,LOC107698842 | coding | upstream | 554682 | 41281161 ~ 41296693 (-) |
clcn6 | clcn6 | coding | upstream | 678892 | 41405371 ~ 41436478 (-) |
LOC103033502 | NA | coding | upstream | 731517 | 41457996 ~ 41493671 (-) |
G57916 | NA | non-coding | downstream | 1707 | 40664520 ~ 40664764 (-) |
G57788 | NA | non-coding | downstream | 375285 | 40290977 ~ 40291186 (-) |
G57782 | NA | non-coding | downstream | 410655 | 40255567 ~ 40255816 (-) |
G57754 | NA | non-coding | downstream | 502191 | 40162984 ~ 40164280 (-) |
G57748 | NA | non-coding | downstream | 504367 | 40161527 ~ 40162104 (-) |
G57925 | wrap73,LOC107678416,LOC107748967,LOC107710786,LOC107595759 | non-coding | upstream | 15035 | 40741514 ~ 40748539 (-) |
G57920 | NA | non-coding | upstream | 35016 | 40761495 ~ 40762172 (-) |
G58031 | mthfr,LOC107687111 | non-coding | upstream | 722734 | 41449213 ~ 41452982 (-) |
G58145 | NA | non-coding | upstream | 1126110 | 41852589 ~ 41944829 (-) |
G58152 | NA | non-coding | upstream | 1149784 | 41876263 ~ 41934574 (-) |
LOC103037008 | LOC108442081,LOC105022382,LOC106567250 | other | downstream | 487330 | 40165400 ~ 40179141 (-) |
G57727 | kdm5c,LOC107550909,LOC107747206,LOC107570512 | other | downstream | 547376 | 40117789 ~ 40119095 (-) |
LOC103030299 | fkbp1aa,fkb1b,fkbp1a,LOC103030299,LOC107553142,LOC107574256,LOC107752559,LOC107707744 | other | downstream | 1103550 | 39521544 ~ 39562921 (-) |
LOC111192682 | NA | other | downstream | 2361005 | 38261117 ~ 38305466 (-) |
LOC103043112 | LOC108438563,LOC108265696,LOC107725303,LOC107653398,LOC107598961,LOC107674288,LOC107734522,LOC107570980,LOC105889772 | other | downstream | 3339735 | 37302047 ~ 37326736 (-) |
tprg1l | tprg1l,LOC107710788,LOC107678419,LOC107698845,LOC106513028 | other | upstream | 22262 | 40748741 ~ 40756014 (-) |
G58022 | LOC103032860,LOC108432146 | other | upstream | 669607 | 41396086 ~ 41398478 (-) |
G58435 | aaas | other | upstream | 2376391 | 43102870 ~ 43107623 (-) |
G58537 | NA | other | upstream | 2955845 | 43682324 ~ 43682684 (-) |
G58649 | NA | other | upstream | 3641421 | 44367900 ~ 44368368 (-) |