polb (polb)



Basic Information


Item Value
gene id polb
gene name polb
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035902.1
NCBI id CM008305.1
chromosome length 52532229
location 35265968 ~ 35274621 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_022670547.1
TGGGAGGGGCTTATCTGTGGAGAGCAGCTGCAGACCCACAGCTTTGTCTCCAGCGTTTCACCCTCAAACTACCCCACAGTACAGATTACAGCGAATAAACCCCAAGATAAACACCGCACAGAACCGCAGATAAACATGAGTAAGCGCAAAGCCCCGCAGGAGACCCTGAACGAGGGAATCACCGACTTTCTCATCGaaTTGGCCAATTATGAAAGAAATGTCAACAGGGCCATTCATAAATACAACGCCTACAGGAAAGCTGCCTCTGTGATTGCTAAATACCCACAAAAAATCAAAAGTGGCACTGAAGCAAAAAAGCTGGATGGAGTTGGTGCAAAGATCGCTGAGAAAATAGATGAGTTTTTATCCACAGGGAAACTCCGTAAACTGGAGAAGATTCGCAGTGACGACACCAGCTCATCTATTAACTTTTTAACTAGAGTGACTGGAATCGGCCCGGCTGCTGCTAGAAAGTTCTTTGAGGAAGGAGTAAAAACTTTGGAAGATCTGAAGAAAATTGAGCACAAACTGAATCACCATCAGCAAATTGGTCTTAAATACTTTGAAGAATTTGAGAAGAGAATTCCCCGCTCAGAGATGCAGAAAATGGAGGCTCTGATATTACAAGAATTAGAGGAGTTGGACTCGGAGTACATTGGCACCATCTGTGGCAGCTACCGACGAGGCGCGGAATCGAGTGGTGATATTGATATCCTGCTGACTCACCCGGACTTTACTTCAGAGTCTGAGAAACAACCGAAACTGCTTCATGCTgtggtggaacacctggagtcGATTGGCTTTATTACTGATACTCTTTCCAAAGGAGACACTAAGTTCATGGGTGTGTGTCAGCTGCAcaaggaggatgaggaggacgAGGATCGTGATCACCGTCGTATTGATATCAGACTGATTCCTAAGGATCAGTATTACTGTGGTGTGCTGTACTTCACTGGGAGTGATATATTCAATAAGAACATGAGAACCCTCGCTCTGGAGAAAGGCTTTACTCTGAATGAGTACACTATCCGTCCGCTAGGCGTCACTGGAATGCCTGGAGAGCCGTTGCTGGTGGACAGTGAGAAGGACATCTTTGACTACATTCATATGAAATACAGAGAACCTAAAGAACGCAGCGAGTGAAGAACagaacaataaaactgaaatacgCCGGTGCTCTTTCTCGTCTTCAGGGccgtatatatattatattatattggtaTTTAGTTCAGTTATAGGTTACAGTCTTTCTTCAGAAGCAGGTGCTGCGTTTAGGGTTTAGGGTAGAGTTGTGTGTTGTGAATGAATGAGTTATGAAACAGTAGCTGAGAGTCTGAATAATGTAGAATGtgagacatttttatttaagatcatgAGAAAAGTGATAacgacagaaaaaaacagactgaATGCAGAAGAAGTTGACGACGCTCGTCAGTGAGCTGTTATTTACGtatttctggattttttttatgttttctcaaTAATTTGAATACATTATACAAGggttttatgttatttaaaatgtttgtcattttttaatgatttgtttTATCATGTGTAGAAGCTCTGCATCAAGCTGTGACAAATGGaagccatttaaaaaaacttcTATCCTTCACTCACTCGCAGGTTTAAGTTActgttacagtatttttttgtttgtttttaaaaggtaattttcttgtttttgggATGATATGCTTTAATATTTGTTATTGATGACTGGTTTGTGTGAAGAGAATACAACGTGCTGAAGAAATGATTAAACACGAGCGTAATCGATCATGTTTTATAAGCGCAGTGATTGATGAGCTGAGTAATATGTAATGAAAAAAGGAAGTGGAGATGATCAGAATGTTTTATGGTGCTATAAACTGGATGTTATATATTTAGTCTGTTTGAGGAAGTTACTGAGAGCCGGAGATTAAAACACTCCTTTGCTATTTTTACCCACAGTGCTTTGGTGCTTTTGTTCACATGAAAACACTATCCAGTACCTCAGGGCTGGACTCCAGAGTGTGGCTGTGTGGAAGATCTGAGTacaactgtataaaataaactTCCTTGCTGAAACAAAAA

Function


symbol description
polb Enables DNA-directed DNA polymerase activity. Predicted to be involved in base-excision repair and double-strand break repair via nonhomologous end joining. Predicted to act upstream of or within DNA biosynthetic process; DNA repair; and DNA replication. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human POLB (DNA polymerase beta).

NR:

description
PREDICTED: DNA polymerase beta

GO:

id name namespace
GO:0006261 DNA-dependent DNA replication biological_process
GO:0006284 base-excision repair biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003887 DNA-directed DNA polymerase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0016829 lyase activity molecular_function

KEGG:

id description
K02330 POLB; DNA polymerase beta

RNA


RNA id representative length rna type GC content exon number start site end site
XM_022670547.1 True 2085 mRNA 0.41 14 35265968 35274621

Neighbor


gene id symbol gene type direction distance location
enkd1 enkd1,LOC107670972 coding upstream 618 35259920 ~ 35265350 (+)
LOC103034472 NA coding upstream 70303 35191804 ~ 35195665 (+)
snap29 snap29,LOC107722859,LOC107560055,LOC107726963 coding upstream 176783 35083719 ~ 35089185 (+)
LOC103037259 pi4ka,LOC108440297,LOC107671001 coding upstream 182676 35039169 ~ 35083292 (+)
LOC103047196 NA coding upstream 247243 35015117 ~ 35018725 (+)
mrpl40 LOC107753002,LOC107671004,LOC107754402,LOC107559600 coding downstream 19302 35293923 ~ 35296002 (+)
gle1 gle1,LOC102792584 coding downstream 25173 35299794 ~ 35308446 (+)
LOC103031612 NA coding downstream 34004 35308625 ~ 35311487 (+)
naif1 naif1 coding downstream 62651 35337272 ~ 35340070 (+)
LOC103038477 fam102aa,LOC108430372,LOC107752986,LOC107671017,LOC107699668,LOC105891604,LOC107754406 coding downstream 66858 35341479 ~ 35365205 (+)
G56479 NA non-coding upstream 11966 35253318 ~ 35254002 (+)
LOC111192732 NA non-coding upstream 47186 35217891 ~ 35218782 (+)
G56465 NA non-coding upstream 66700 35197445 ~ 35199268 (+)
G56459 NA non-coding upstream 88989 35171898 ~ 35176979 (+)
G56448 NA non-coding upstream 129920 35133583 ~ 35136048 (+)
G56482 NA non-coding downstream 10830 35285451 ~ 35287472 (+)
G56487 seta,LOC103031932,LOC107752982,LOC107699670,LOC108265615,LOC107754404,LOC107671021 non-coding downstream 37494 35312115 ~ 35315555 (+)
G56492 zdhhc12,LOC107560045,LOC106955948 non-coding downstream 45258 35319879 ~ 35320773 (+)
G56499 NA non-coding downstream 117681 35392302 ~ 35468036 (+)
G56649 NA non-coding downstream 255283 35529904 ~ 35530234 (+)
LOC103047498 NA other upstream 276683 34961800 ~ 34989285 (+)
G56414 tcf7l1,LOC107721095,LOC107556226 other upstream 514405 34713218 ~ 34751563 (+)
fgf17 fgf17,LOC103025711,LOC107698084,LOC107678395,LOC107721084 other upstream 754284 34503114 ~ 34511684 (+)
LOC103037863 adra2b,LOC108440671,LOC108264887,LOC107554404,LOC107753091 other upstream 1625891 33635152 ~ 33640077 (+)
izumo1 NA other upstream 1670150 33564828 ~ 33595818 (+)
LOC103032256 dynll1,LOC103397138,LOC107554284,LOC107559583,LOC100698873 other downstream 1458 35276079 ~ 35284271 (+)
G56504 NA other downstream 146097 35420718 ~ 35458877 (+)
G56701 pola2,LOC107710902,LOC107657899 other downstream 681483 35956104 ~ 35964510 (+)
G57066 NA other downstream 1730652 37005273 ~ 37005798 (+)
agtpbp1 agtpbp1 other downstream 3834623 39109244 ~ 39153476 (+)

Expression



Co-expression Network