LOC103035335 (atp2a2,atp2a2a,LOC107757297,LOC108265716)



Basic Information


Item Value
gene id LOC103035335
gene name atp2a2,atp2a2a,LOC107757297,LOC108265716
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035902.1
NCBI id CM008305.1
chromosome length 52532229
location 36296278 ~ 36331569 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_022670581.1
GTGGACGCGGCGCGAGGCTCACCGGCACAGGTCCCGGTACACACACCCCGAGCGCGTGAGAACGCCAGACAGAGAGCGCGAGCTCAGCGGAGTGCGGGAGTGAGTGTGATGCGGTAATAATAAAGCGGAACCTGGAGATAGTGCACCTACCTGTTTAAAGGTAGGAAAAGGAAGAAGACCctcactcctcctcctcacacCTGTGGAGAAAACTACTACTGCTGCCACTGCTCACCTGAGACAGAGACCGGACTACTGTGAACGAGAGACAGCTACTCTGCCTGTTCTGAACGCGGATAGAcaagcagacagacacacagacggatagacagacagacagtggcGGCAGTGGCGGGATGGAGAGCGCGCACACTAAGAGTGTGGAGGAAGTTTACAGCTTTTTCGGCGTGAACGAGAGCACGGGACTGGGGCTCGAGCAGGTTAAACGGCAGCGTGAGAAATGGGGACCGAACGAATTACCAGCTGAAGAAGGAAAATCTATATGGGAGCTGGTTATTGAGCAGTTTGAGGATTTACTCGTGCGCATTCTTCTACTGGCAGCTTGTATATCATTTGTTTTAGCCTGGTTTGAAGAGGGAGAAGAGACCATCACAGCCTTTGTGGAGCCTTTCGTAATCCTGCTTATTCTTATAGCCAATGCCATCGTAGGGGTGTGGCAGGAGCGTAATGCTGAGAATGCCATCGAGGCTCTGAAGGAATACGAGCCTGAGATGGGGAAGGTGTACCGGCAGGATAGGAAAACCGTGCAGAGGATCAAAGCCAAAGACATTGTGCCTGGAGACATTGTGGAGGTGGCTGTGGGAGACAAAGTCCCTGCAGATATCCGCATTTGTTCCATCAAGTCCACAACACTGAGAGTGGACCAGTCCATCCTCACGGGTGAGTCTGTCTCGGTGATTAAACACACCGACCCCGTCCCCGACCCCCGCGCCGTCAATCAGGACAAGAAGAACATGCTGTTCTCAGGAACCAACATCGCAGCTGGTAAGGCGGTGGGCGTGGTGGTGGCCACGGGCGTGAACACGGAGATCGGTAAGATCCGAGATGAGATGGCGTCCACCGAGCAGGAGAGGACCCCCCTGCAGCAGAAGCTGGACGAGTTCGGGGAGCAGCTCTCTAAGGTCATCTCTCTCATCTGCATCGCCGTGTGGATCATCAACATCGGCCACTTCAACGACCCGGTGCACGGCGGCTCCTGGATCCGGGGGGCTGTGTATTACTTTAAGATTGCCGTGGCTCTGGCTGTAGCCGCCATTCCTGAGGGGCTTCCCGCCGTCATCACCACCTGCCTGGCCCTGGGTACTCGCCGCATGGCCAAGAAGAACGCCATCGTTCGCTCCCTGCCCTCGGTGGAGACGCTGGGCTGCACCTCCGTCATCTGCTCCGACAAGACCGGAACCCTCACCACCAATCAGATGTCCGTGTGCAGaATGTTTATTTTGGAGAAAGCGGAGGGTGAGAGCTGCTCTCTGACTGAGTTCACCATCTCCGGATCCACATACGCACCTGAAGGAGACGTGTACCTGGATAACCGTCCGGTGAAGTGCTCTGGATATGATGCTCTGGTGGAGTTGGCCACCATCTGTTCTCTGTGTAACGACTCCTCTCTGGACTATAACGAGtctaaAGGTGTGTATGAGAAGGTGGGCGAGGCGACGGAGACggctctgacctgtctggtggaGAAGATGAACGTGTTTGATACGGATGTCCGGAGTCTTTCCAGGATTGAGAGAGCCAACGCCTGTAACTCTgtgATCAAGCAGCTGATGAAGAAGGAGTTCACCCTGGAGTTCTCGCGGGACAGGAAGTCCATGTCCGTGTACTGCAGCCCCAGCAAGAGCAAGTCCTCTTCCTGCAAGATGTTTGTGAAGggAGCTCCAGAGGGAGTGATTGACAGGTGTACATACGTACGTGTGGGTGGCACTCGGGTGCCCATGTCCAGCGGCATTAAGGAGAAGATCATGGCTGTTATCAGGGATTACGGGACAGGACGGGACACCCTGCGATGTCTCGCTCTCGCCACTCGCGACAGCCCACTCAAAAAAGAGGAAATGGTTCTTAGCGACACCGCGCGCTTCCAGGATTATGAGTCTGACCTGACCTTCGTGGGCTGCGTGGGCATGTTGGACCCGCCCAGGACCGAAGTGGCCGCCTCCATCAAGCTGTGTCGGCAGGCGGGTATCCGGGTCATCATGATCACGGGGGATAATAAGGGTACGGCCGTGGCGATCTGCAGACGCATCGGTATCTTCTCCGAGGAGGACGACGTCCACCGCATGGCCTTCACCGGCCGCGAGTTCGACGACCTCTCCCCCCACAGCCAGCGCGAGGCCGTCACCAACGCCCGCTGCTTCGCGCGAGTCGAGCCCTCGCACAAGTCCAAGATCGTGGAGTTTCTGCAGGGCTTTGATGAGATCACTGCCATGACGGGGGATGGGGTGAACGATGCCCCTGCCCTGAAAAAGGCAGAAATTGGCATCGCCATGGGCTCTGGCACTGCTGTGGCCAAGACAGCCTCGGAAATGGTCCTCGCTGACGACAACTTTTCCTCCATCGTGGCCGCTGTAGAGGAAGGACGCGCCATTTACAACAACATGAAGCAGTTCATCCGCTACCTCATCTCCTCCAACGTGGGAGAGGTCGTCTGCATCTTCCTGACGGCAGCACTGGGTTTTCCTGAAGCTCTGATCCCGGTTCAGCTGCTGTGGGTTAACCTCGTGACGGACGGTCTGCCCGCCACCGCCCTGGGCTTCAACCCCCCCGACCTGGATATCATGAATAAACCCCCCCGCAATGCCAAGGAGCCCCTCATCTCCGGATGGCTGTTTTTCCGATACCTGGCCATTGGCTGCTACGTGGGAGCTGCTACAGTGGGCGCTGCAGCCTGGTGGTTCACTGTGGCTGATGACGGACCTCAGATCACCCTCTACCAGCTGagtCACTTCCTGCAGTGTTCTCCTGATAATCCTGACTTTCAGGATCTGGAGTGTCACGTGTTCGAGTCCCCGTACCCCATGACCATGGCCCTGTCTGTACTCGTCACCATCGAGATGTGCAATGCTCTTAACAGCCTGTCTGAGAACCAGTCTCTGCTGAGGATGCCCCCGTGGGAGAACGTCTGGCTGCTGGGAGCGATCTGCCTCTCCATGTCGCTGCACTTCCTCATCCTGTATGTGGAGCCGCTGCCGGTCATCTTCCAGATCACTCCTCTGAACGTCACTCAGTGGCTGATGGTGCTGAAGATCTCTCTGCCCGTCATCCTGCTGGACGAGCTGCTGAAGTTCGTGGCGAGAAACTACCTGGAGCCGGGTAAAGACCTGGAGGCGGAGCCCCGGCGGGGAGGCGGAGCTCAGGGCGTCTCCTGGCCCTTTGTGGCCGTCTCCCTCCCCCTGGTGGTGTGGCTTTACAGCACAGACACTAACATCAGCCGCCTGCTGCTGAGACCCTCCTGACTGATCTGAGACCTGCAGTGACGCTAACAAGCACCCGTccaaaataacagaaacacCATTAACCAGGAAACACATTAACCCAGTCAGCGTTTGCACAAACCTCCACGAACTGTActgtcttttattttaatatctatacttttggtgtgaaatgagtgatgattgattgattgccatttttttatcattttattttaaagcacacttaaagacatttttctatggtttgttcttttttataaagAGAGTGAATTTGTTCTCAGCTGATCTTGAATTCCTTTGTCAGATGATCTAATAAGAAGTAAGAAAATAGACACTATATAtttacatggacaaaagtattgggacacctacacaGGGGCTTTTCTTATGGAATCCCATTTTGAATCCataaccatcagtgtgtagtacgTCCCCCTGTTCCCAATTCGAAACACtaattttatgatttatgaccatttttcttacttttattgttgtaattctttaaatcaaaaacatgaaaaatgattaataataattatttctgCCTCTGCTGTGGGAGAGTTCAGCTACCTCATTTTAAGTCGTATTAACCCTGAACCCTGGCTATATTataccatttttaaagtttagaaAACCCACCCGGCATGTTATCTTTCTGCTTTTATTCacatacaacatatatatatatatattttaattttgtatttatttgatcaCATTGCCAAACAGTTAGTCAGTTTTTAGTTTGTTGTTTTAATGGGTTACTTTTTTGTTCCATGACCTACTTAAGGTTGTGGAAGGGGCACAGTTCTAGAACTATAGCTAAACCACGGTGTGTAAtgggtgttagtgtgtgttaatgtgtgtgtgtgtgtgttaactgtGTGCCAATCAGCATTAATTATCTTAGTACCAGGTTGAATAAACTCAGCACAATGGtcctaccgta
>XM_022670582.1
GTGGACGCGGCGCGAGGCTCACCGGCACAGGTCCCGGTACACACACCCCGAGCGCGTGAGAACGCCAGACAGAGAGCGCGAGCTCAGCGGAGTGCGGGAGTGAGTGTGATGCGGTAATAATAAAGCGGAACCTGGAGATAGTGCACCTACCTGTTTAAAGGTAGGAAAAGGAAGAAGACCctcactcctcctcctcacacCTGTGGAGAAAACTACTACTGCTGCCACTGCTCACCTGAGACAGAGACCGGACTACTGTGAACGAGAGACAGCTACTCTGCCTGTTCTGAACGCGGATAGAcaagcagacagacacacagacggatagacagacagacagtggcGGCAGTGGCGGGATGGAGAGCGCGCACACTAAGAGTGTGGAGGAAGTTTACAGCTTTTTCGGCGTGAACGAGAGCACGGGACTGGGGCTCGAGCAGGTTAAACGGCAGCGTGAGAAATGGGGACCGAACGAATTACCAGCTGAAGAAGGAAAATCTATATGGGAGCTGGTTATTGAGCAGTTTGAGGATTTACTCGTGCGCATTCTTCTACTGGCAGCTTGTATATCATTTGTTTTAGCCTGGTTTGAAGAGGGAGAAGAGACCATCACAGCCTTTGTGGAGCCTTTCGTAATCCTGCTTATTCTTATAGCCAATGCCATCGTAGGGGTGTGGCAGGAGCGTAATGCTGAGAATGCCATCGAGGCTCTGAAGGAATACGAGCCTGAGATGGGGAAGGTGTACCGGCAGGATAGGAAAACCGTGCAGAGGATCAAAGCCAAAGACATTGTGCCTGGAGACATTGTGGAGGTGGCTGTGGGAGACAAAGTCCCTGCAGATATCCGCATTTGTTCCATCAAGTCCACAACACTGAGAGTGGACCAGTCCATCCTCACGGGTGAGTCTGTCTCGGTGATTAAACACACCGACCCCGTCCCCGACCCCCGCGCCGTCAATCAGGACAAGAAGAACATGCTGTTCTCAGGAACCAACATCGCAGCTGGTAAGGCGGTGGGCGTGGTGGTGGCCACGGGCGTGAACACGGAGATCGGTAAGATCCGAGATGAGATGGCGTCCACCGAGCAGGAGAGGACCCCCCTGCAGCAGAAGCTGGACGAGTTCGGGGAGCAGCTCTCTAAGGTCATCTCTCTCATCTGCATCGCCGTGTGGATCATCAACATCGGCCACTTCAACGACCCGGTGCACGGCGGCTCCTGGATCCGGGGGGCTGTGTATTACTTTAAGATTGCCGTGGCTCTGGCTGTAGCCGCCATTCCTGAGGGGCTTCCCGCCGTCATCACCACCTGCCTGGCCCTGGGTACTCGCCGCATGGCCAAGAAGAACGCCATCGTTCGCTCCCTGCCCTCGGTGGAGACGCTGGGCTGCACCTCCGTCATCTGCTCCGACAAGACCGGAACCCTCACCACCAATCAGATGTCCGTGTGCAGaATGTTTATTTTGGAGAAAGCGGAGGGTGAGAGCTGCTCTCTGACTGAGTTCACCATCTCCGGATCCACATACGCACCTGAAGGAGACGTGTACCTGGATAACCGTCCGGTGAAGTGCTCTGGATATGATGCTCTGGTGGAGTTGGCCACCATCTGTTCTCTGTGTAACGACTCCTCTCTGGACTATAACGAGtctaaAGGTGTGTATGAGAAGGTGGGCGAGGCGACGGAGACggctctgacctgtctggtggaGAAGATGAACGTGTTTGATACGGATGTCCGGAGTCTTTCCAGGATTGAGAGAGCCAACGCCTGTAACTCTgtgATCAAGCAGCTGATGAAGAAGGAGTTCACCCTGGAGTTCTCGCGGGACAGGAAGTCCATGTCCGTGTACTGCAGCCCCAGCAAGAGCAAGTCCTCTTCCTGCAAGATGTTTGTGAAGggAGCTCCAGAGGGAGTGATTGACAGGTGTACATACGTACGTGTGGGTGGCACTCGGGTGCCCATGTCCAGCGGCATTAAGGAGAAGATCATGGCTGTTATCAGGGATTACGGGACAGGACGGGACACCCTGCGATGTCTCGCTCTCGCCACTCGCGACAGCCCACTCAAAAAAGAGGAAATGGTTCTTAGCGACACCGCGCGCTTCCAGGATTATGAGTCTGACCTGACCTTCGTGGGCTGCGTGGGCATGTTGGACCCGCCCAGGACCGAAGTGGCCGCCTCCATCAAGCTGTGTCGGCAGGCGGGTATCCGGGTCATCATGATCACGGGGGATAATAAGGGTACGGCCGTGGCGATCTGCAGACGCATCGGTATCTTCTCCGAGGAGGACGACGTCCACCGCATGGCCTTCACCGGCCGCGAGTTCGACGACCTCTCCCCCCACAGCCAGCGCGAGGCCGTCACCAACGCCCGCTGCTTCGCGCGAGTCGAGCCCTCGCACAAGTCCAAGATCGTGGAGTTTCTGCAGGGCTTTGATGAGATCACTGCCATGACGGGGGATGGGGTGAACGATGCCCCTGCCCTGAAAAAGGCAGAAATTGGCATCGCCATGGGCTCTGGCACTGCTGTGGCCAAGACAGCCTCGGAAATGGTCCTCGCTGACGACAACTTTTCCTCCATCGTGGCCGCTGTAGAGGAAGGACGCGCCATTTACAACAACATGAAGCAGTTCATCCGCTACCTCATCTCCTCCAACGTGGGAGAGGTCGTCTGCATCTTCCTGACGGCAGCACTGGGTTTTCCTGAAGCTCTGATCCCGGTTCAGCTGCTGTGGGTTAACCTCGTGACGGACGGTCTGCCCGCCACCGCCCTGGGCTTCAACCCCCCCGACCTGGATATCATGAATAAACCCCCCCGCAATGCCAAGGAGCCCCTCATCTCCGGATGGCTGTTTTTCCGATACCTGGCCATTGGCTGCTACGTGGGAGCTGCTACAGTGGGCGCTGCAGCCTGGTGGTTCACTGTGGCTGATGACGGACCTCAGATCACCCTCTACCAGCTGagtCACTTCCTGCAGTGTTCTCCTGATAATCCTGACTTTCAGGATCTGGAGTGTCACGTGTTCGAGTCCCCGTACCCCATGACCATGGCCCTGTCTGTACTCGTCACCATCGAGATGTGCAATGCTCTTAACAGCCTGTCTGAGAACCAGTCTCTGCTGAGGATGCCCCCGTGGGAGAACGTCTGGCTGCTGGGAGCGATCTGCCTCTCCATGTCGCTGCACTTCCTCATCCTGTATGTGGAGCCGCTGCCGGTCATCTTCCAGATCACTCCTCTGAACGTCACTCAGTGGCTGATGGTGCTGAAGATCTCTCTGCCCGTCATCCTGCTGGACGAGCTGCTGAAGTTCGTGGCGAGAAACTACCTGGAGCCGGctcGGGCGATTTGAGCCTGGCTCTCGGAAACTCTTTGCGGAAGCTGTAAAAGGTTTTAATAGATTATAGAAAGTGTGATTTGAGCAGTACCACATCATCCAAGACCTGCATGCCATGAACTGTGCTACAgagaaaaatcaaataaaaatcaaaataaaagtacaggTGTATAAATAATTAGCTTAGAAAAGGTActggaaaaaaacaggtttGTTAATTTGGAGTGAGTGGTAAAGACTGTtcgttttttaagtttttaaaagagACTTTAATTGATTAATAGAATTAAGTTAAAATCTGAAGGGAAATGAGGAGCTCTTCATGGTGCATGCCCCTTAAGATACTCAGACATTTTGTTCTGGGAAGATTATAAGCTTTTTTGTATAGCACAGCAACACttaatttatatatagatatatatataatagagatTTTATATATAGAGATAAAGATGTATAAGAAAAAACAGATGGCAGATGGCATTAGTGTTTACCAggcaccatttttttttttgtctattttttgtcAGAAGACGTTTTTAGAGATATAATACTAGAATTTCCCTCGGAAAccaataaataatgtatttctcttttttaatcagCCGATTCTGAGCGTTATCTCTCGGCACAGTGGGAAGATGTGCGTCCAGTTTTAGAGCAGATCAGAGTTTCAGCTGAGAGGAGTTTCAGTGATGAGCGATGGCGAGACACTGTTCAATCAGTGTTGAGTATTGTAATTATCACAATGACTTACGGTCAATAAAGGGACAATAAAAGAg

Function


symbol description
atp2a2a Predicted to enable P-type calcium transporter activity. Acts upstream of or within heart looping and regulation of heart contraction. Predicted to be located in membrane and sarcoplasmic reticulum. Predicted to be active in sarcoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in cardiovascular system; musculature system; pectoral fin; polster; and somite. Human ortholog(s) of this gene implicated in acrokeratosis verruciformis; essential hypertension; keratosis follicularis; and pulmonary hypertension. Orthologous to human ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2).
atp2a2 Enables several functions, including P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential; S100 protein binding activity; and protein C-terminus binding activity. Involved in several processes, including calcium ion transport from cytosol to endoplasmic reticulum; macroautophagy; and mitochondrion-endoplasmic reticulum membrane tethering. Located in endoplasmic reticulum membrane and longitudinal sarcoplasmic reticulum. Part of calcium ion-transporting ATPase complex. Colocalizes with intercalated disc. Implicated in acrokeratosis verruciformis; essential hypertension; keratosis follicularis; and pulmonary hypertension.

NR:

description
PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1

GO:

id name namespace
GO:0008016 regulation of heart contraction biological_process
GO:0006816 calcium ion transport biological_process
GO:0001947 heart looping biological_process
GO:0016021 integral component of membrane cellular_component
GO:0005388 calcium transmembrane transporter activity, phosphorylative mechanism molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function

KEGG:

id description
K05853 ATP2A; P-type Ca2+ transporter type 2A

RNA


RNA id representative length rna type GC content exon number start site end site
XM_022670581.1 True 4410 mRNA 0.52 20 36296278 36329181
XM_022670582.1 False 4114 mRNA 0.53 21 36296278 36331569

Neighbor


gene id symbol gene type direction distance location
ift81 ift81,LOC106585468 coding upstream 6477 36262411 ~ 36289801 (+)
LOC103035951 LOC108438364,LOC107598973,LOC107757293 coding upstream 91175 36099455 ~ 36205103 (+)
fxn fxn coding upstream 214825 36072072 ~ 36081453 (+)
dimt1 dimt1,LOC107699721 coding upstream 325347 35965198 ~ 35970931 (+)
cenph cenph coding upstream 340426 35948598 ~ 35955852 (+)
ntng2 ntng2,ntng2a,LOC108438355,LOC106585788 coding downstream 161933 36493502 ~ 36585412 (+)
endog endog,LOC107736532 coding downstream 264447 36596016 ~ 36598896 (+)
LOC103040549 NA coding downstream 732830 37064399 ~ 37085499 (+)
LOC111192679 NA coding downstream 754873 37086442 ~ 37091387 (+)
LOC103044321 plekha2,LOC108414546 coding downstream 763145 37094714 ~ 37110794 (+)
G56756 NA non-coding upstream 52553 36171914 ~ 36243725 (+)
G56767 fnbp1,LOC108264955 non-coding upstream 68625 36227237 ~ 36227653 (+)
G56764 NA non-coding upstream 75074 36219895 ~ 36221204 (+)
G56749 NA non-coding upstream 85013 36201442 ~ 36211265 (+)
G56753 NA non-coding upstream 144788 36129056 ~ 36151490 (+)
G56786 rapgef1,LOC108265900 non-coding downstream 16057 36347626 ~ 36353279 (+)
G56811 NA non-coding downstream 80361 36411930 ~ 36412215 (+)
G56812 NA non-coding downstream 80856 36412425 ~ 36412757 (+)
G56836 NA non-coding downstream 229196 36560765 ~ 36579538 (+)
G56837 NA non-coding downstream 229811 36561380 ~ 36634827 (+)
G56701 pola2,LOC107710902,LOC107657899 other upstream 331768 35956104 ~ 35964510 (+)
G56504 NA other upstream 837401 35420718 ~ 35458877 (+)
LOC103032256 dynll1,LOC103397138,LOC107554284,LOC107559583,LOC100698873 other upstream 1012007 35276079 ~ 35284271 (+)
ikbkb ikbkb,vdac3,LOC107560056,LOC107671013,LOC107754399 other upstream 1023750 35226485 ~ 35272528 (+)
LOC103047498 NA other upstream 1306993 34961800 ~ 34989285 (+)
G57066 NA other downstream 673704 37005273 ~ 37005798 (+)
agtpbp1 agtpbp1 other downstream 2777675 39109244 ~ 39153476 (+)
frmd3 frmd3,LOC107678471 other downstream 2960502 39292071 ~ 39370585 (+)
LOC103039219 iqsec2,LOC107747221,LOC107683900,LOC107702804,LOC108265842 other downstream 3635521 39967090 ~ 40090271 (+)
G57664 NA other downstream 3713084 40044653 ~ 40046467 (+)

Expression



Co-expression Network