hsd17b4 (hsd17b4)


Basic Information

Item Value
gene id hsd17b4
gene name hsd17b4
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035902.1
NCBI id CM008305.1
chromosome length 52532229
location 8976218 ~ 8995752 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022671109.1
aACGTGACGGGGTGACGTCCGCTGTGAGCAGTAGGTGAAGAGTCAGGGTGAAGTaaccgtccgtccgtccgtttACCTGCAGCTCTTCAGCATGCCTGCGCCTTTATCCTTCTCCGGGAGAGTGGTGGTGGTTACGGGAGCGGGTGGAGGCCTTGGAAGAGAGTATGCATTGGCGTTTGGTGAGAGAGGAGCTTCAGTTGTTGTGAATGACCTTGGGGGAGATATAAAAGGTGGTGGGAAGAGTTCAGCAGCCGCTGATAAAGTGGTTGAGGAGATAAAAGCTAAAGGTGGCAAAGCTGTTGCAAATTATGATTCAGTAGAAGATGGTGAAAAGCTAATCCAAACAGCTTTGGATGCATTTGGAAGAATAGATATCTTGGTAAACAATGCTGGGATCCTGCGTGATCGATCTTTTGCTAGAACCAGTGACCTAGACTGGGACCTCATTCATCGAGTGCATCTGAGGGGCTCCTTCTTAGTTACCCGGGCAGCATGGAATCACATGAAGAACCAGAAGTTTGGAAGAATCATCATGACCTCATCAGCTGCAGGGATCTACGGCAATTTTGGCCAGGCAAACTACAGCGCGGCCAAGCTGGGCCTCCTGGGACTGGCCAATACTTTGGCCATAGAAGGCCGGAAGTACAACATCCACTGCAATACCATCGCCCCCACAGCTGGCTCACGTCTCACCCAGACTGTTATGCCACCAGATCTCTTAGAGTCCTTGAAAGCAGAGTACGTGGCTCCTCTTGTTCTTTGGCTGTGCCATGAGGAGTGTCAGGAGAGTGGCGGCCTCTTTGAGGTTGGCGCTGGCTGGATTGGCAAATTGCGGTGGGAGAGGACCGTGGGCAGTATTGTCCGGCATAAAGACCAGAGCATGAGCCCAGAGGAGGTTCGGGACAAGTGGGACCAGATATGTGACTTTAACAATGCAACTAAACCAGCTACTATTAATGAGTCCTTGCAAACGCTGGTGGAGGTGCTGTCAGCAGTGGATACCGGGGATGCAATAAGAGCCAATCCAACCAGTGCTTTGAGCCCAGCAGATTCTGGCATCAACCCTacacTGGCTGTAGGAGCAGTGCTTCCAGAAATGACCTTCACCTACACCCCCATGCGCTCTATCCTCTATGCTTTGGGAGTGGGCATGTCCACTAAGGAACCTGATCACCTCAAGTTCCTCTACGAAGGCCACGAGGACTTCAGTTGCCTTCCAACTTTTGGTGTCATCCCTGCACAGGCCTCCATGATGGAAGGAGGTCTTAGCACGGTTCCAGGACTCAATTTCGACCCCACCAGGcttctgcatggAGAGCAGTACCTGGAATTGTACAAACCATTGCCCACCTCAGGAACCCTGACTTCAAAGGCATCCATAGCAGACGTCCTCGACAAGGGGTCTGGAGCAGTCATACTCTTGGATGTTCACACTTACAGCAAGCAGGAGCTGGTGTGCTACAATCAGTTCTCGGTGTTCATTGTTGGTTCTGGGGGATTCGGAGGAAAGCGGTCTTCAGATAAAGCTGTGCCCACAGTTCCTCCTCCAAATAGAGCTCCAGATGCAGTGATGGTTGACAAGACTTCTAGAGATCAGGCTGCTTTGTACAGGTTGAGTGGTGATTGGAACCCGCTTCACATAGATCCAAGCTTTGCAGCAATGGGAGGCTTCAAAACCCCAATTCTTCATGGACTGTGCTCTTTTGGATTCGCTGCCCGCCATGTCCTGAAGCATTATGCTGACAATGATGTTTCCAAATTCAAGTCCATAAAGgtgcGGTTTGTGAAACCAGTGCTACCAGGAGAGTCCATTCAGACAGAGATGTGGAAAGAGGGAAACAGAATTCATCTAGTGTGCAAAGTCAAGGAGAGTGGAGCTGTTGTACTGTCTGGGGCATATATAGATTTACATGCAGCACCAGACGCTTCTGTCAGCACTGCTCCAGCCGAGAGCGGCGGCCTTCAGAGTGATTTAGTGTTTGCGGAGATTGGCCGGCGGATCAAAGACCTGGGAGCTGAACTTGTGAAGAAAGTTAACGCCGTTTTTGGATGGGAAATCACTAAAGGAGGAAAGACAGCTGCTCAGTGGACCATTGATCTGAAGACTGGAAACGGTGCCCTCCATAAAGGGCCATACAGCGGCAAATCTGATGTGACTTTTACTGTATCAGACGAGGACTTCATGGAGGTGGTGATGGGGAAGCTCAACCCGCAGAAGGCATTCTTCGCTGGTAAATTGAAGGTGAGAGGGAATATCATGCTGAGCCAGAAGCTGGAGGTGATACTGAAGGATTATGCCAAGCTGTGAGTCTCCAACCAGTCCGTCCAATGCCCGAGAGCGATGCAAATGCAGACTTCCTGACACTCTCACTTATACAGGGGGGTATCAGTGATGGTAATTTCTAGAATCTTTGTGTGCAATGAAAACTAAAATCTAATACAGGAATGAAACTAtcaaatttgataaaatatcAAGCTAATGCTGAGAGAATGAATGAATCTAACCAAATACTTGGCATTAGAGAAATGCACTGGTTCTAGTGAATCTTTTTAGTTCAGGGTTTGGTTCATTTACACCTTGATTATTATGCTTTCATTAGTCAGGTTTATtcagatcagctcagagctGGACCAGCTGAAATTCTTGCTGAATGCATTAATTATAAGAGGTGTCCACAGACATGTGGaggtagtgtatatattttataggctGAAATGTGAGATAATTGAACATGGCACAGTTATGGAATTGATGTAACGGTTAACTTCAGCTAGTGCCCAGCCGTGAAATCATGCagtttcctttcctttctgccATCTGTTGAAGAAGCAAGTGAAGTACAGCTTAACAATGCCGTTAATTTGTCGTATAAATCAGaagagatggatggataaatcaGAAGAGATGGATGATTTTTCTGATGTAGGTCTAATGTTTGGCAATTTTGAAACACTAAGCTAATTCAAAATATCTCATCTTGTCAGATTTACTCACCCTGACCTTAATCTTATTGTCTAAATAATGAAAAGTAATGCATATGTTTAATATGTGCTGCTAATTTGTAATAAATCTCACTTTTGTGTAACACAA

Function

symbol description
hsd17b4 Predicted to enable 17-beta-hydroxysteroid dehydrogenase (NAD+) activity; 3-hydroxyacyl-CoA dehydrogenase activity; and enoyl-CoA hydratase activity. Acts upstream of or within embryonic organ development and neuron development. Predicted to be active in peroxisome. Human ortholog(s) of this gene implicated in D-bifunctional protein deficiency; Perrault syndrome; and Stiff-Person syndrome. Orthologous to human HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4).

NR:

description
peroxisomal multifunctional enzyme type 2

GO: NA

KEGG:

id description
K12405 HSD17B4; (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022671109.1 True 3091 mRNA 0.47 24 8976218 8995752

Neighbor

gene id symbol gene type direction distance location
LOC103034488 LOC108437599 coding upstream 706884 8264164 ~ 8269334 (+)
LOC103035131 LOC108437597,LOC108437601 coding upstream 713488 8259603 ~ 8262730 (+)
LOC103034161 LOC108437597,LOC108437601,LOC108265423 coding upstream 718266 8254568 ~ 8257952 (+)
LOC103033636 NA coding upstream 731494 8243882 ~ 8244724 (+)
slc20a2 slc20a2,LOC107594502,LOC107724891,LOC107669617,LOC107711867,LOC107602837 coding upstream 799435 8109822 ~ 8176783 (+)
sema6a sema6a,LOC106585847,LOC106580184 coding downstream 89286 9085038 ~ 9203129 (+)
cdo1 cdo1,LOC102791980 coding downstream 330948 9326700 ~ 9335342 (+)
tmed7 tmed7,LOC103042236,LOC102200599,LOC101168626,LOC100701005 coding downstream 349886 9345638 ~ 9351678 (+)
catsper3 NA coding downstream 357321 9353073 ~ 9354864 (+)
fem1c fem1c,LOC106580179,LOC107728259 coding downstream 362015 9357767 ~ 9364491 (+)
G50770 NA non-coding upstream 29846 8945273 ~ 8946372 (+)
G50656 NA non-coding upstream 220209 8755645 ~ 8756009 (+)
G50580 NA non-coding upstream 673308 8302516 ~ 8302910 (+)
G50565 NA non-coding upstream 772799 8202437 ~ 8203419 (+)
G50550 NA non-coding upstream 873931 8102075 ~ 8102287 (+)
LOC107197475 NA non-coding downstream 9240 9004992 ~ 9006646 (+)
G50818 NA non-coding downstream 208264 9204016 ~ 9204217 (+)
G50822 NA non-coding downstream 257421 9253173 ~ 9254126 (+)
G50841 ap3s1 non-coding downstream 313508 9309260 ~ 9324163 (+)
G50886 NA non-coding downstream 618776 9614528 ~ 9622057 (+)
G50583 LOC108437602,LOC103398889 other upstream 631704 8342940 ~ 8344514 (+)
G50563 smarcad1,smarcad1a,LOC108437598,LOC107568413,LOC107751429 other upstream 697462 8270248 ~ 8278756 (+)
G50568 NA other upstream 755056 8207342 ~ 8221162 (+)
c6h9orf3 NA other upstream 1092160 7730684 ~ 7884058 (+)
trnae-cuc NA other upstream 1991957 6984190 ~ 6984261 (+)
G50889 grid2,LOC107556295 other downstream 647622 9643374 ~ 9782721 (+)
nfu1 nfu1,LOC108265347,LOC107553147,LOC105890045 other downstream 1127968 10123720 ~ 10130801 (+)
LOC103038184 acsl2,LOC107553163,LOC107710839,LOC107665192,LOC107716609,LOC108426687,LOC107678403 other downstream 1692133 10687885 ~ 10757255 (+)
G51423 cunh1orf21,zgc:92140,LOC107676598,LOC107585858,LOC107750760,LOC107700167,LOC107548740 other downstream 2836929 11832681 ~ 11882021 (+)
LOC103022344 foxd1,LOC103022344,LOC108265081,LOC106569011 other downstream 3088328 12084080 ~ 12129300 (+)

Expression


Co-expression Network