XLOC_007931 (her11)


Basic Information

Item Value
gene id XLOC_007931
gene name her11
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007125.7
NCBI id CM002898.2
chromosome length 52660232
location 30538482 ~ 30540967 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00015477
GGTGGAAAGTTCACGAGGCCTACGTCACTGCCACCTCCTAGCCAATTAAATTCCACCAGGCGGGGTAAAAGTTCCCGTTTGGTGCGTTTTCATTTCAGCAGTTTCCCATATCCTCGAATGAAGAGCACACCGACTTTCAACATGACGAAGACAGAAGGGATCAAAAGAaGGCTAAAGCCTGTCATAGAGAAGAAAAGGAGAGATCGGATTAACCACAATCTAGACGCATTAAGAGATCTGCTCTTCAAGAACACTGCAGACACTCGTTTACAAAATCCGAAACTGGAAAAAGCAGAGATTTTAGACCTTGCAGTTCAGTACATCAAAAAGACTATAAGAAAGACTGAAACAGCAAGGAATTCCAATCAAATGGACTGTAAGTCAACCCAGAATCAGTTTGTTATATCTCCTGCGGGTCCTCTCTACACTAGTGACTACTGCAGGAGGTTTAAAACATCTGAGCAAAACGAGGTTCTCCTGAATCTGGGAGTCAGTCAGAACCTAAGTGGTTCTTCCAAAACAGGGAATAAACTAGTTTCCCAGAAAGGCTTCCTCTTATCCCCACCAGGCCAGAACTACCACCAGGAGCTGCTCTTACACCCTGAATCATCTTTGTATGGGTCAAGTTTATTGCGTCAATCGACTTCTCCCTCCATCTCATCATCATCACAATACAGTTCTCCGCCATCATCTCCCACTTTTACCAGCACATCCTGCTCTCCCTCATCGTCTCCCCCTTGTCCTTCAACATCTTGTGCTGCCTTTCCTGACCAACTGTCTCCTCTAATAACTCCACTTTCACTTCAGAGGCCTGTTTTTGTTCCTCAAGCCATTCTGCCCCACATGACCAGAGATTTGACTCCACCACATTCGCCTGTCCTGGCTCTTAGACAGGATCCCTTCCCTCTTCCAAACCAGCATGCCTGGAGACCATGGAGCTGAAATCTGACCACTCTGTTGTTCCCCATTTTAGGCACTGCTCCAATGGAGAAATGATGGTGTTCTCTAAGAGGGACCTTATGGACATATGTTGGGGCATGTGCACAGTTTTGTCTATTATTATTCAATGACTTGTACTTTCAATTtactatttattgttttatcCAGTGATTGTCTTCACTGGTATGTGTGTGATTGCAGCAGTGGAATAAATGAGTTGAATCAAT

Function

symbol description
her11 Enables protein heterodimerization activity. Acts upstream of or within midbrain-hindbrain boundary development and negative regulation of neurogenesis. Predicted to be active in nucleus. Is expressed in several structures, including heart; liver; margin; midbrain hindbrain boundary; and midbrain hindbrain boundary neural plate. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human HES7 (hes family bHLH transcription factor 7).

GO:

id name namespace
GO:0007219 Notch signaling pathway biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0050767 regulation of neurogenesis biological_process
GO:0050768 negative regulation of neurogenesis biological_process
GO:0030917 midbrain-hindbrain boundary development biological_process
GO:0005634 nucleus cellular_component
GO:0005515 protein binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function
GO:0046982 protein heterodimerization activity molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040824-4 Enables protein heterodimerization activity. Acts upstream of or within midbrain-hindbrain boundary development and negative regulation of neurogenesis. Predicted to be active in nucleus. Is expressed in several structures, including heart; liver; margin; midbrain hindbrain boundary; and midbrain hindbrain boundary neural plate. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human HES7 (hes family bHLH transcription factor 7).

Ensembl:

ensembl_id ENSDARG00000002707

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00015477 True 1166 mRNA 0.45 4 30538482 30540967

Neighbor

gene id symbol gene type direction distance location
XLOC_007930 FP015860.1 coding downstream 1598 30511481 ~ 30536884 (-)
XLOC_007929 micu3b coding downstream 47719 30453342 ~ 30490763 (-)
XLOC_007928 zdhhc2 coding downstream 86264 30426956 ~ 30452218 (-)
XLOC_007927 slc7a2 coding downstream 148337 30367602 ~ 30390145 (-)
XLOC_007926 pdgfrl coding downstream 172286 30359124 ~ 30366196 (-)
XLOC_007932 pfdn6 coding upstream 9430 30550397 ~ 30557637 (-)
XLOC_007933 tmem265 coding upstream 39714 30580681 ~ 30587861 (-)
XLOC_007934 npas4a coding upstream 95988 30636955 ~ 30642819 (-)
XLOC_007935 efemp2a coding upstream 128695 30669662 ~ 30704075 (-)
XLOC_007936 fibpa coding upstream 172769 30713736 ~ 30724165 (-)
XLOC_007641 CU855896.1 misc downstream 28130642 2407736 ~ 2407840 (-)
XLOC_007640 CU855896.2 misc downstream 28131051 2407328 ~ 2407431 (-)
XLOC_007639 CU855896.3 misc downstream 28131410 2406945 ~ 2407072 (-)
XLOC_007925 NA non-coding downstream 240311 30297374 ~ 30298171 (-)
XLOC_007920 NA non-coding downstream 831439 29706704 ~ 29707043 (-)
XLOC_007919 NA non-coding downstream 836848 29701320 ~ 29701634 (-)
XLOC_007918 CABZ01048945.1 non-coding downstream 1185359 29353007 ~ 29353123 (-)
XLOC_007951 BX248522.1 non-coding upstream 785634 31326601 ~ 31326717 (-)
XLOC_007952 NA non-coding upstream 925639 31466606 ~ 31469460 (-)
XLOC_007954 dre-mir-457b non-coding upstream 980963 31521930 ~ 31522007 (-)
XLOC_007957 BX511227.4 non-coding upstream 1092179 31633146 ~ 31635433 (-)
XLOC_007960 AL929434.1 non-coding upstream 1318463 31859430 ~ 31859506 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000000_10217060_10219305 NA coding CI01000000 null 10216835 ~ 10219305 (-)