XLOC_008199 (pcsk7)



Basic Information


Item Value
gene id XLOC_008199
gene name pcsk7
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 518092 ~ 542133 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00016541
TGACGATCGCGGATGTTTGTCTCACAACCTGATCTGTGGAGTGATGTCGCTGTTTCGGTTGACAGATAATGAAGATAAACACATCGCGAATAAAACAAAGAGACACACGCGCTGGTGAAGTAGAGCGGCGTTATTAACAGCTAATCTgatgtggagtgtgtgtgtggcatggCGTCCTGCTCCTCCCGGGTGTGTTTGGGACTGTACCCGCTGCTCCTGctgttctcctcctcctcctcctcatgtGCTCCGGGGCGCTCCTGGGCGGTGCAACTTCAGCCGGACTCCCTGAGCTCTGCCGGGTCTCCGGATCTGCTGGCCCAGGCGGTGGCACAGGATGTGGGTCTGCGGAGCCACGGGCAGATCGGGCAGCTGGAGGGGCACTACCTGCTGTGCCAGGACCCAGCGCAGGGCGAGGACTGGCGCTGGATGGAGGCTGCTCTGGACAGGCACCCTCACGTGGCCTGGCACTCGCAGGAAAATGTGCTGCGGCGCTCCAAGAGGAGTGTGCACTTCAATGACCCTAAATTTCCCAGTCAGTGGCACCTGCACAATGACATGAAGCGAGGGATGGACATCAATGTGACGGGCGTGTGGGAGAGGAACATCACCGGCGCGGGCGTCACTGTGGTGGTGGTGGACGACGGCATTCAGCACAACCTGGCAGACATCCAGCCTAACTATAGTCCTGAAGGCAGCTATGACCTGAACTCTAATGACCCAGACCCCATGCCTCACCCAGACGGTCCCAGTGATAATCATCACGGCACGCGCTGCGCTGGAGAGATCGCCGCCGTCTCCAACAACAGCTTCTGTGCGGTGGGCGTGGCATACGGCAGCAGGGTGGCCGgcatCAGAGTGTTGGACGGGCCGCTCACAGACAGTATGGAGGCCATCGCTTTCAACAAGCATTACCAGGTCAATGACATCTACAGCTGcagTTGGGGTCCAGATGATGACGGCCGGACGGTTGACGGACCGCATCCATTAGGCAAGGCGGCGCTGCAGCACGGTGTGATCGCGGGCCGCAAGGGTTTCGGCAGCATCTTCATTGTGGCCAGTGGCAATGGAGGACAGAATCAGGACAACTGCAACTACGACGGCTACGCTAACTCCATCTACACCGTCACCATCGGAGCAGTGGACGAGAGCGGCAGGAAACCAACCTATGCGGAGGAGTGTGCGTCCATGCTGGCCGTCACCTTCAGCAGCGGGAACACACCGCTGCGCAGCATAGTGACGTCAGACTGGTCTCTGCAGAGCGGCACCGGCTGTACTAGTGGGCACACGGGCACCTCCGCCGCTGCTCCTCTGGCTGCAGGGATGGTGGCGCTGATGCTGCAGGTGCGGCCCTGTCTGAGCTGGCGAGATGTGCAGCACATCATCACCTACACCGCCACACAGcatGACCTTCAGGCGGACTGGGTCACTAATGGAGCTGGTTTCCATCACAGCCACAAGTACGGCTTCGGCCTCCTGAACGCCTGGAGACTCGTCAATGCTGCAAAGGTTTGGGAGTCTGTCCCCTTCCTGGTGTCCTACCAGAGTCCAGTTCTGAGGGTCAATGAGGTCATCACGACCTCCACAAACCTCACACAAACCTGGAACGtgTCTGAGTCTGACCTGCAGCGCTCCGGTATGCAGACTCTGGAGCATGTGTCCGTGACTCTCAGCATTCAGCATCCCAGAAGAGGAAACCTGCAGATCCTGCTGCTCTGCCCCAGCGGCATCAGCTCCCTGATTGGAGCACGCAGGGCACTGGACGTAGATTCTGCAGGCCTGACGGACTGGACGTTCTCCACCGTGCGCTGCTGGGGAGAGCAAGCCGAGGGCCAGTACAGCCTGCTGATCATGGACGACGcGCCTCTGTCCTCAGGTATTCTGAAGAGCTGGAAACTGACGCTGTACGGCTCGTCTCTGTCCCATCAGCAggtcacagacagacagagagTTGTTGAGGAGGCCATGAGTGGACATTACCTGAGCAGCAGCTTCTCTCTGCCGTGTCCACCGGGTATAGATGTGCCTGCGGAGATCGTCAACCCCTTCACCTCCAGCAGCCTCAagtCTCTGCTGCTGCTGGGTTGTTTCACGCTCTTCTGGTCGCTCTACTACACTCTGGAGGTGGTGCTCACACACTGGGACTGGCGCGGTGGGTGTGTCCGCGGGCGGGACGGCGACGCCGGATACTCCAGACTGTCCCGGGACGAGGCTCAGACGGACCCTCAGCAGGTGGAGGTCCTGCTGGAGACACACAGCCAGGACAAAGTGCTGCTCATAGCGGACACACACACGTAACCCTCAGGAACACACTCCGTCTTCTGTCTCCGAGACTTCAGGTTgcacttctgtgtgtgtgtgtgcgtgtgcgtgtgtgtgtgagtgaatgctGGATTACTGGTGGCCTTGCTTTggtttatttactgttattttaatgacaatGTCTTCttacaggagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcgtgtgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgtgtgtgcgcttgtgtgtgtgtgtgcttgtgtgtaagtgagtgtgtgtgagtgtgtgtgtgagtgtgtgtgtgagtgtgtgtgtgtgtgatatcttCTGAAGTTTAATTTAATGGTGTTTGTCCTGATGATGGTGATGGATTGAGCGCCTGAGtgtggatgatgatgatgatgatgatgatgatgatgatgatgatgatgatgatgatgtgtataAACTCCTCTGACTTGAACTGTGAGATGAGCAGGACTGAGATTGTCGGGTCTTTTACTGCTTCTGGACTGTTTTTACTGTGGTACTCTTGGGAACAAGAGCAAGATGTGGTTTGAATAAAAACTAAAAGGG

Function


symbol description
pcsk7 Predicted to enable serine-type endopeptidase activity. Acts upstream of or within brain development; chordate embryonic development; and sensory organ development. Predicted to be active in membrane and trans-Golgi network. Predicted to be integral component of Golgi membrane. Is expressed in several structures, including eye; gill; integument; liver; and pleuroperitoneal region. Orthologous to human PCSK7 (proprotein convertase subtilisin/kexin type 7).

GO:

id name namespace
GO:0043009 chordate embryonic development biological_process
GO:0016485 protein processing biological_process
GO:0048840 otolith development biological_process
GO:0006508 proteolysis biological_process
GO:0001654 eye development biological_process
GO:0007420 brain development biological_process
GO:0005802 trans-Golgi network cellular_component
GO:0030173 integral component of Golgi membrane cellular_component
GO:0016020 membrane cellular_component
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008236 serine-type peptidase activity molecular_function

KEGG:

id description
ko01002 Peptidases and inhibitors
ko03110 Chaperones and folding catalysts

ZFIN:

id description
ZDB-GENE-030131-7293 Predicted to enable serine-type endopeptidase activity. Acts upstream of or within brain development; chordate embryonic development; and sensory organ development. Predicted to be active in membrane and trans-Golgi network. Predicted to be integral component of Golgi membrane. Is expressed in several structures, including eye; gill; integument; liver; and pleuroperitoneal region. Orthologous to human PCSK7 (proprotein convertase subtilisin/kexin type 7).

Ensembl:

ensembl_id ENSDARG00000069968

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00016541 True 2913 mRNA 0.57 16 518092 542133

Neighbor


gene id symbol gene type direction distance location
XLOC_008198 ftr86 coding upstream 1342 509126 ~ 516750 (+)
XLOC_008197 NA coding upstream 18269 497208 ~ 499823 (+)
XLOC_008196 si:ch1073-280e3.1 coding upstream 21543 478524 ~ 496549 (+)
XLOC_008195 med17 coding upstream 72082 436776 ~ 446010 (+)
XLOC_008194 nipsnap2 coding upstream 104551 404891 ~ 413541 (+)
XLOC_008200 NA coding downstream 4020 546153 ~ 547881 (+)
XLOC_008201 si:ch73-144d13.4 coding downstream 35565 577698 ~ 581955 (+)
XLOC_008202 si:ch211-210b2.1 coding downstream 75948 618081 ~ 637162 (+)
XLOC_008203 znf1013 coding downstream 96324 638457 ~ 643471 (+)
XLOC_008204 NA coding downstream 116229 658362 ~ 669444 (+)
XLOC_008463 BX663520.1 misc downstream 20710058 21252191 ~ 21252282 (+)
XLOC_008206 NA non-coding downstream 226048 768181 ~ 768435 (+)
XLOC_008218 CU571333.1 non-coding downstream 536856 1078989 ~ 1079104 (+)
XLOC_008225 NA non-coding downstream 679684 1221817 ~ 1234693 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000072_00153905_00173611 NA coding CI01000072 null 153335 ~ 174190 (-)
bowfin (Amia calva) AMCG00004622 NA coding CM030121.1 CM030121.1 54977847 ~ 54998428 (-)