XLOC_008290 (mrap)



Basic Information


Item Value
gene id XLOC_008290
gene name mrap
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 5628363 ~ 5630452 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00016664
AACTGAACCAATAACTTGTAAGAGAAATGTGAACCttcagataaaataaaataaataaatgttctacGAAGGGGACGGGGCTTCATTGTGTTTTCGTAACCGTGATTCTCATGGGCGGGATCAAGGATTTAAAAATCACTCACGCTTCTGGTGCCgtttcacattcacaaacaccCAAGAAAATGAAAAACTCCTCAGAATACGTGTGGGGCTATGAGTACTACTATGATTACGTGGATCCAGTCTTGGTGAATGCGAGTACACTGAAGTACAGCAGATattCGATTGTGCTGATATTCTGGATGATTCTAGCTGCATTCATTGGGTTCTTCTTCTTGATTTTGTCACTTATTTCACATTCAGGACAACTGCCAagGGGCCCTCGAGTCAAAAAATCCGGTTTGCCACTGATGAAAGGTTATGCATCATCTCAGTAAAGACATAAATAAGAAGAATCTTCAAGAAGTAAACTCATGCGCTAGTGTTCACCAAGCTTAATTTCATGCGACAACAGAAAATGATTAATCAGTCACAATAAACAAATGACAAGATCAT

Function


symbol description
mrap Enables melanocortin receptor binding activity and peptide hormone binding activity. Contributes to corticotropin receptor activity. Acts upstream of or within positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway and protein localization to cell surface. Located in plasma membrane. Is expressed in adipose tissue; head kidney; and liver. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Orthologous to human MRAP (melanocortin 2 receptor accessory protein).

GO:

id name namespace
GO:0106071 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway biological_process
GO:0034394 protein localization to cell surface biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0031779 melanocortin receptor binding molecular_function
GO:0017046 peptide hormone binding molecular_function
GO:0004978 corticotropin receptor activity molecular_function

KEGG:

id description
ko04927 Cortisol synthesis and secretion
ko04934 Cushing syndrome

ZFIN:

id description
ZDB-GENE-060503-387 Enables melanocortin receptor binding activity and peptide hormone binding activity. Contributes to corticotropin receptor activity. Acts upstream of or within positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway and protein localization to cell surface. Located in plasma membrane. Is expressed in adipose tissue; head kidney; and liver. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Orthologous to human MRAP (melanocortin 2 receptor accessory protein).

Ensembl:

ensembl_id ENSDARG00000091992

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00016664 True 555 mRNA 0.39 3 5628363 5630452

Neighbor


gene id symbol gene type direction distance location
XLOC_008289 NA coding upstream 156855 5468098 ~ 5471508 (+)
XLOC_008288 or112-1 coding upstream 263855 5360407 ~ 5364508 (+)
XLOC_008287 CABZ01018874.1 coding upstream 283859 5343186 ~ 5344504 (+)
XLOC_008286 si:ch1073-22e3.1 coding upstream 286984 5339056 ~ 5341379 (+)
XLOC_008285 or113-2 coding upstream 294107 5332900 ~ 5334256 (+)
XLOC_008291 NA coding downstream 211105 5841557 ~ 5853342 (+)
XLOC_008292 BX088654.1 coding downstream 224659 5855111 ~ 5855225 (+)
XLOC_008293 get1 coding downstream 271518 5901970 ~ 5916820 (+)
XLOC_008294 sh3bgr coding downstream 293399 5923851 ~ 5958803 (+)
XLOC_008295 igsf5b coding downstream 343457 5973909 ~ 6017920 (+)
XLOC_008463 BX663520.1 misc downstream 15621739 21252191 ~ 21252282 (+)
XLOC_008278 NA non-coding upstream 371581 5256501 ~ 5256782 (+)
XLOC_008271 NA non-coding upstream 1073935 4553896 ~ 4554428 (+)
XLOC_008270 NA non-coding upstream 1096398 4528549 ~ 4531965 (+)
XLOC_008269 NA non-coding upstream 1307348 4313091 ~ 4321015 (+)
XLOC_008297 NA non-coding downstream 528557 6159009 ~ 6160503 (+)
XLOC_008299 CU655863.1 non-coding downstream 928598 6559050 ~ 6559185 (+)
XLOC_008301 CU633984.1 non-coding downstream 1048069 6678521 ~ 6727082 (+)

Expression



Co-expression Network