XLOC_008453 (ulk2)



Basic Information


Item Value
gene id XLOC_008453
gene name ulk2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 20843161 ~ 20894776 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00016930
CGGAGGAACACGATATGATGGTCTCGTTCTCCTGCGAGAGGAGAGCTCTACTGTCATTGTAATGCTGCAACTGTGCGATCAAGATCAAATTCCTCTCCGAACGAACAGAAGATAAAACGATAAACTCCGTTCACATAACGGATCGTGCTTTTAACGTCTTTTTTACGCTTTTGTTAAAAGCGAAGCACTGATGTTTTTCTGCATTGTCCCTCGATATCGAAAGCAGGACAGACGGGTGAACTGAAGAAATGGTGTATTGTTACCCAGCACTCATATGGATCTGAAGGAGATAATCTTATTTTTGCAGATGGACAGATGACTATTACATTAAACGCATCGGGGAACGGTGCTCTGGATCGCTTGTTTTGTAAACTAACCTGCTAGAATTTTAGCGACGCGTTTTGACTGTGTAAAATAGATGTGGGAGCACTTCTAGACATATTGAGATTTAACGTTACCTGCTGTGTTGTCATTATAAACATTGCTGTATTGTCGCTTGCTGGCTGTCATTGTAGCCAGCTCGCGATGGGCAACTCAGTGACCCGCCGCGCAGTTATTGACTTAACGAGGCACTGTTACAGCACGAGAGTGAGGGCGTTTGCAACCTCTTTCTTTCCTTTTAAACTGAACTGACAACATGTAGCTCGGAAACTATACATCTTAGTTGGATTAATAGCTATTTCATCAAGCTATTTTGCGAAATGCCTTGTTAACTGGAGTCAGAGAGCGACAACGAAAATAGTTATGCGCATCTAGCATCTAACGTTAGTCACTTAAACTTCACACTTAGCTTTGTTTTGATTCTTGATTTTCAGCCAGACGGTTATAAATAAACTCTCAAGTATACTATATAGTCTCTAGCATTGATAATTTGGGGATGACAGTGTTCTTGAACAGACTGTCGCCAGGATTAAAGAGAGTTTGAGGAACTTGTCCCTATAGCAGCCTCTCCATCTCAAGCTGTTGTGTATCATCACCGGACACCTGCCAAAAATATGGAGACGGTGGGAGATTTTGAATACAGCCGAAAAGACCTCATCGGACACGGAGCCTTTGCGGTCGTCTTCAAGGGAAGACATAAAAAGAAGACTGATTGGGAGGTCGCCATCAAAAGCATTAACAAAAAGAATCTCTCCAAATCCCAGATTCTGCTTggcaaagaaataaaaattttaaagGAACTCCAGCATGAAAACATTGTGGCGCTCTATGATGTCCAGGAAACGCCAAGTTCTGTATTTCTGGTTATGGAGTACTGCAATGGAGGAGACCTGGCAGATTATTTGCAAGCCAAGGGCACTCTGAGAGAGGACACACTGAGGGTCTTTCTACAGCAGATTGCAGCCGCCATGCGAATCCTTAACAGCAAGGGGATCATCCATCGAGACCTCAAACCCCAGAACATCCTGCTGTCCTACACGGGCCGCAAGAAGTCCAGCATCAACGGCATACGCATCAAGATCGCCGACTTTGGTTTTGCGAGATACCTCCAGAGCAACATGATGGCAGCCACACTATGTGGATCCCCGATGTACATGGCCCCGGAGGTCATCATGTCCCAGAATTATGATGCCAAAGCTGACCTGTGGAGCATTGGGACTGTTATTTACCAGTGCCTCGTGGGAAAGCCGCCTTTTCAGGCTAACAGTCCCCAGGACTTGAGGATGTTCTATGAAAAGAACAAGTCTTTGGTGCCAAACATCCCGAGAGAGACATCTCCTCAACTGGAAGACCTGCTGCTGGGGCTTCTTCAGAGAAACCAGAAAGATCGTATAGATTTTGACACTTTCTTCAGTCATCCTTTCTTGGAACCGATATCAACTATCAAAAAATCATGCCCTGTTCCAGTGCCCTCATGTTCAGGCTTGGTCTCAGACAGCACATGTGGCAGCTCTCCATCCTGCCGTTACGTGTCTCCTCCGTCACTGCCAGACATGCAGACTCTCCCTGAAGACGTGTTGTCCTCTCCACCTCTCGGTCCTCCCAACTATCTGCAGCTGTCCAAGGAGTCCGGCGGCAGCACCAGCAGCAAAAACTCCTCCTGTGACACAGATGACTTTGTGCTGGTGCCGCATCTGTCTGGGGAACAGTCCTATGACCTTCCAATGGGGGCAGTGGGTCGCAGGCCATCCAGTGAATTTCTCCTGTGTGGAGGGTCACCGCAGCCATCTACTGGACAGACGCCAATGGTGTCACCACGGAGCGAGACCACGCCAATTCCTGTGCCCACACAGGTGCGAAACTACCAGCGGATCAAACAGAACCTCTCCAGCAGCCCAACCACAACACTTTATGGCTCTCCCAGGTCAGGCACAGTGCGTCGCTCCAACACAAGCCCCATGGGCTTCCCTAAAATGGTGTCTGCTTCCCCAAGCCCTGCAGATACTGTCCAAACAGTGGGGCGACGTCTCTCTACTGGCAGCTCTCGGCCCTACTCACCCTCTCCACTGGTGGGCACGATTCCTGAGCAGCTCGGCCACTGTTGCTGTGGTCACCCTCAGAGCCATGAACCGCGCAGTCGCAGCTCTTCAGGCGGTTCCCCAGTGCCATCCTCTCAGTTACTGGGCGCTCGTCTTCAGAGTGCGCCGACACTGACGGACATCTACCAGAGCAAGCAGAAGCTCCACAAGCAGCTGTCTGACCCAGTGCACCCCACCTCCTCCGCCTATCCCAGCAACCACTCTCCTCAGCTCGGCCGGCCCGCAAACCTCGGCACCTCCCCAACCAAACACCTCGGTTCCTCTCCTCGcacctctgattggctgacaaaATCACCGCTCCCCACTATCATTGGCTCTCCAACTAAGGTAACAGCTCCATTCAAAATCCCTAAAACTCAAGCCTCTTGCAATCTCATGGCCCTGGCCGACAGCCCCATCCCCAACAAGACTCTGATGGATGGACGTGAACTTTGTGCTCATCACTGTACAGCGTATCCCAGCAGCAGACAGCCCGCACCTGAGGCTAGCAAGACTTCCTTTGGCAGGTCTGTAAGCGCTGGCAGACTGTCTGAGCCTCCGGTACGGATCACTCTAGGAGGACAGCCGTACCAGGGCAGCACAGACAGCCTCAACACAGAGAGACCCATGGACACAGCCCCGGCCGGGATGTGTGCTTTGGCAGCAGGAGGAGGGAGTCCTCGCACCGTCGTGTTCACGGTGGGTTCACCCCCCAGCAGCAGCACCCCTCCAACCTGCAGCCATCTGGCCTCTCGCCCGCGCGCCACCTCAGtgggCTCCAACAGCTCTGCCGGTTCGCTCTGCTCCACCAGTGGTAAGGTGTACATGGGCTCTCCTCCAGGCATGACCATCGGCAGCTCTCCACCCGGAGCAGAAGCAGGTCCCAGCAGCCTCCGTTACGTCCCATACGGCACCTCTCCACCCAGCTTGGATGGCTTCATTACCTTTGAAGCTCCAGAACTGCCAGAGGAGACGCTGATGGAGCGTGAGCACACAGACACACTGATGTACCTGCGGATGATGCTGTCTTTCACGGACTGTGTGCTGGAGATCGCCGCTCTGCGGGCCGGAGGGCCTGATCTGGGTGCATCGGCTGCTTCTCTCTATCCTCCTCAGGACAGTGTGGTGGTGGACCAGATCAGTCAGCTCAGTAGAGAGTGGGGGCAGGTGGAGCAGCTGGTGTTGTATATGAAAGCAGCTCAGCTTCTGGCCTCCTCGCTGCACCTCGCCAAAGCCCAGATCAAATCTGCCAAACTCAACCCGTCTACTGCCGTCAAACAGGTGGTGAAGAGTCTGAACGAGCGCTACAAGAGCTGTATTTCCCTGTGCCGTCGCCTCACAGACAAACTCAACCACTTCTTCTCTGACAAGCAGCGCTTTGTGGACGAGATCAACAGTGTGACAGCAGAAAAGCTCATTTATAACCACGCTGTGGAGATGGTGCAGTCGGCCGCTCTGgatgagatgtttcagcagacTGAGGACATCGCTTATCGCTACAACAAAGCCTCCATGCTGCTGGAAGGCCTGACCAAGATCCTCCAGGACCCAGCTGATATTGAGAACGTTATTAAATACAAGGCCAGTGTGGACCGGAGGATCTCAGCTTTGTGTTACTGCACCGTCACCCTGTACGAATAAAGAGCGCAAACTCTCTAAAACAAGCTCTCACTCCAGGGACCATCATCTTCTCCGACCACAGAGAAGAATAAACCAATCCCTTGTTTTCTTTTCGTAGCAGTCGAAGCACTTTCAGTTCCTTTTGATTCCTTCCATCACACGCAACAGACCAAGTAttaccttttagttttttttgctgATGACATTGAGAAGGACGTGCACAAGTTCACTACCAAAGATGACAACCATTTGGATCCATCTTCTCTTTTTACAACTTTTAAGAACACAAGCCGAAGGGATTTTTGAACTGGGAAACTTAAGAAGCCCAACAATGAACATCAATGCAAATCAATTCATCCTGTTGTTTTCTACTGCACTCTACTTGCTCTGATTATTTATTGGTTTTGAACATGTATATATGCTAGTGTTATTGATGATAAAGTGTTGATAGACAACTTGACGTGGATTTGAATGTTGGACTGTAATTACCGGTACCACACAAATACGCAGTCACGCGGTTAGGAGGAATCTGTAGTATTTACAAAATCAGCTTTGAAGCAAATGCACTTTATTGAGGCAGACGTGGAAAAGAGACGCTCGTCCCAGCGTTTGCTCCGCTTTTTTCCATATCGAAATAAAATCCTCAGAGTATATCCAGAAGGCCGTGAGCACACTGGCGTCACATAAAAGCCTCATGGTGAAATCATCCATAATGGTCAAAAATACTTGAGTAGTTACTTACTTTTTGATTCATCTGTACTGATACGTTGTTTTTTATGTTGATATTAATACTGTAGCTTTTTTTAACCGCAGCTGTAAATACTGTACattctgcatgtgtgttttttattttggagtgAATGCGAGCGAGCGATGCGTGTGATTAAAGGCGGCGGACGCTGCACCGTCCCTCAAATAAAGAGCACAAAATATCCTTCTTTTTTTGTAGATGGCAACAACGTCCACACAAACTTCTTACAGACAATTCTCACTTTGCATGGCAGCTCTCGACAAACACCCGTGTTTGAGGATATATACTGACTTTGTGAGGTAAACAGGATCAAGCGCAGCCCACTGCCAGGCTCTGCTTTCCTCCCTTTATCCACGTGCAGTGTTTGTGCGGCCGCACTTCCCAGGTGCAGTCCAGTTTCAGGATCCCCAAGTACCGAAAGCATGACATTTGAGAAGTGTACATGATCTGAACACCTCGCTCCCTCTTTCCTTCACTCTGCCTCTGTTTTTTAATCTTTATAACGTGAGCCTACAACGCCTTTACTGTACAGAAGGAGAAGGCTGAGGTTCATTCTGACACCCAAATCATGCATATCTGTAGTTGTAGGACTGAGGAGAACTGTGTACAGATCACCCGTTAGACAAAATTAGTACCCGTGGAGCATTAGAATGTATCTGCCCTAGGTTTAGCACCTTTccgaaaataaacaaacactttttttcccaGCCTATCACAAGCTGACACGATCATGGCCGACGCAGCCTGAAGGTCCATGTTCCCTTGATTTCAAATGtggatgttttaaatgttttaaaccatGTGTGTTTTACCAAGGGCATCTGTGTTGTCTGAAACTGTAGAAATACAGCTtttgtttattaaacagattGATTTTATCCTGTTA
>TCONS_00016931
GAAACACAGAAGCTTCACGTTCTTTACTTTTAAAGATCACATGTTGAATGATTCTTTAAGCttgaggttttttattttaaggtttttgtCTCAGAAATGGGGTTGGAAAAGCAGCCTGACTGGATTGCCACCTTGTTTTCTGGGTTTCTCAGGTCACCGCAGCCATCTACTGGACAGACGCCAATGGTGTCACCACGGAGCGAGACCACGCCAATTCCTGTGCCCACACAGGTGCGAAACTACCAGCGGATCAAACAGAACCTCTCCAGCAGCCCAACCACAACACTTTATGGCTCTCCCAGGTCAGGCACAGTGCGTCGCTCCAACACAAGCCCCATGGGCTTCCCTAAAATGGTGTCTGCTTCCCCAAGCCCTGCAGATACTGTCCAAACAGTGGGGCGACGTCTCTCTACTGGCAGCTCTCGGCCCTACTCACCCTCTCCACTGGTGGGCACGATTCCTGAGCAGCTCGGCCACTGTTGCTGTGGTCACCCTCAGAGCCATGAACCGCGCAGTCGCAGCTCTTCAGGCGGTTCCCCAGTGCCATCCTCTCAGTTACTGGGCGCTCGTCTTCAGAGTGCGCCGACACTGACGGACATCTACCAGAGCAAGCAGAAGCTCCACAAGCAGCTGTCTGACCCAGTGCACCCCACCTCCTCCGCCTATCCCAGCAACCACTCTCCTCAGCTCGG
>TCONS_00016932
GGCAGGTGGAGCAGCTGGTGTTGTATATGAAAGCAGCTCAGCTTCTGGCCTCCTCGCTGCACCTCGCCAAAGCCCAGATCAAATCTGCCAAACTCAACCCGTCTACTGCCGTCAAACAGGTGGTGAAGAGTCTGAACGAGCGCTACAAGAGCTGTATTTCCCTGTGCCGTCGCCTCACAGACAAACTCAACCACTTCTTCTCTGACAAGCAGCGCTTTGTGGACGAGATCAACAGTGTGACAGCAGAAAAGCTCATTTATAACCACGCTGTGGAGATGGTGCAGTCGGCCGCTCTGgatgagatgtttcagcagacTGAGGACATCGCTTATCGCTACAACAAAGCCTCCATGCTGCTGGAAGGCCTGACCAAGATCCTCCAGGACCCAGCTGATATTGAGAACGTTATTAAATGTGAGTGAATTTagtaaaattaatcatttacatttcattatatATTCACTTTCAAAACACTCACTTTAGGCAATTAGGACTCTtcttaaatcaaattaaatataatgacaaaaaatgtaatac

Function


symbol description
ulk2 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within dendrite arborization; habenula development; and regulation of dendrite morphogenesis. Predicted to be active in phagophore assembly site membrane. Is expressed in habenula; hatching gland; polster; sensory system; and trigeminal placode. Orthologous to human ULK2 (unc-51 like autophagy activating kinase 2).

GO:

id name namespace
GO:0016358 dendrite development biological_process
GO:0048814 regulation of dendrite morphogenesis biological_process
GO:0140059 dendrite arborization biological_process
GO:0006468 protein phosphorylation biological_process
GO:0021986 habenula development biological_process
GO:0048675 axon extension biological_process
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
ko04150 mTOR signaling pathway
ko04140 Autophagy - animal
ko04138 Autophagy - yeast
ko04136 Autophagy - other
ko04139 Mitophagy - yeast
ko04212 Longevity regulating pathway - worm
ko05010 Alzheimer disease
ko05014 Amyotrophic lateral sclerosis
ko05016 Huntington disease
ko05017 Spinocerebellar ataxia
ko05022 Pathways of neurodegeneration - multiple diseases
ko01001 Protein kinases
ko04131 Membrane trafficking
ko03029 Mitochondrial biogenesis

ZFIN:

id description
ZDB-GENE-090218-30 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within dendrite arborization; habenula development; and regulation of dendrite morphogenesis. Predicted to be active in phagophore assembly site membrane. Is expressed in habenula; hatching gland; polster; sensory system; and trigeminal placode. Orthologous to human ULK2 (unc-51 like autophagy activating kinase 2).

Ensembl:

ensembl_id ENSDARG00000097205

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00016930 False 5716 mRNA 0.49 27 20843161 20894776
TCONS_00016931 False 692 lncRNA 0.55 4 20882960 20885734
TCONS_00016932 True 537 lncRNA 0.45 3 20891319 20892743

Neighbor


gene id symbol gene type direction distance location
XLOC_008452 aldh3a1 coding upstream 34037 20799943 ~ 20809124 (+)
XLOC_008451 sgsm2 coding upstream 199334 20543770 ~ 20643827 (+)
XLOC_008450 tnfaip1 coding upstream 301976 20529197 ~ 20541185 (+)
XLOC_008449 NA coding upstream 384285 20411292 ~ 20458876 (+)
XLOC_008448 cox7a1 coding upstream 437365 20403084 ~ 20405796 (+)
XLOC_008454 CR848784.1 coding downstream 2327 20897103 ~ 20901355 (+)
XLOC_008455 NA coding downstream 109957 21004733 ~ 21093616 (+)
XLOC_008456 NA coding downstream 122873 21017649 ~ 21037778 (+)
XLOC_008457 NA coding downstream 269259 21164035 ~ 21164573 (+)
XLOC_008458 CR626907.1 coding downstream 272366 21167142 ~ 21177049 (+)
XLOC_008463 BX663520.1 misc downstream 357415 21252191 ~ 21252282 (+)
XLOC_008436 NA non-coding upstream 1087343 19752881 ~ 19755818 (+)
XLOC_008435 CR626889.1 non-coding upstream 1121407 19688875 ~ 19721754 (+)
XLOC_008428 BX324206.3 non-coding upstream 1551784 19287632 ~ 19291377 (+)
XLOC_008427 BX324206.2 non-coding upstream 1557018 19284842 ~ 19286143 (+)

Expression



Co-expression Network