XLOC_008857 (otx5)



Basic Information


Item Value
gene id XLOC_008857
gene name otx5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 47903864 ~ 47909281 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00017522
ATTCATCTCACTGTCACCGGGAGACCGAGACACGCGCACCGAGCGCTCAGCCGCAGCACCGGACACACTAACAGACCGCTGatgagctcacacacacacacgatcaacacatacacacactcgagCTCGTCTACACGCTGCTGACTGATAGAAAAAGTCCATCAGagacagaaacacacagaaagagagagagaggaggagagagaaagagagagagagagagtttagtCATGATGTCCTACATGAAACAGCCTCATTACTCCGTTAACGGGTTGACTCTGTCCGGTACCGGGATGGATCTCCTGCACTCCGCCGTCGGTTACCCTAACACTCCACGGAAACAGCGGCGCGAAAGAACCACCTTCACGCGTGCGCAGTTGGACGTGCTGGAGGCGCTGTTCTCCAAAACCCGATACCCGGACATATTCATGAGGGAAGAAGTGGCTCTCAAGATCAACCTGCCCGAGTCTAGAGTCCAGGTCTGGTTTAAGAACCGTCGTGCCAAATGccgtcagcagcagcagcagcagaccaGCGGTCAGACCAAACCCAGACCACCCAAGAAGAAGTCTTCTCCGGCTCGTGACTCCAGTGCCAGTGAGCCCAGCGCCAGCACCAGTGGCCCCTACAGCCCCCCACCACCCCCGCCTGGCACCGCCATCACCCCCAGCTCCAGCAGCGCCACCGTATCTATCTGGAGCCCGGCCTCCATTTCTCCACTGCCCGACCCGCTGTCCGCCCCCAGCACCGCCTGCCTGCAGCGCTCCAGCTATCCTATGACCTACAGCCAAGCGCCGGCCTATGGGCAGAGCTACGCCGCCTCCTCATCCTACTTTACAGGCCTGGACTGCAGCTCGTACCTGTCCCCAATGCACCCGCAGCTATCAGCCAGCGGGGGCGCTCTCAGCCCAATGAGCGGAGCCCTCAGCCAATCGCCGGCCTCGCTTTCATCTCAGGGTTACACCGCCGCATCACTGGGCTTCGGCGCCGTCGACTGCTTAGATTATAAAGACCAGACGTCAGCCTGGAAACTGAACTTCAACGCCCCAGACTGTCTGGACTACAAGGACCAGAATTCCTGGAAGTTCCAGGTGCTGTAGGCGGAGCTTCAGATAAAAAAGGCGGAGTTTAAGAAACGCATTCGTTTAGAAACTACAGAACTTTCTGTGCAGTTAAAGAGTgggggtctcatttataaaccTTGCATAGAAACCTTATTAATAGTGAACGTACAGCTgaatatgtttaatttatttttaattattatgacTTTATGGTCATATATGATGATTAAAGTTGttaagtcaacatttaaagttaaAATAGTTTCCTTGGAGTCTACTCACAGCTGCGCACATGCTCCTGttcagtttgtttttaataaaatcaaaCTTTTGCCTGTTAAGTGGAGTACGCTTATTTGCACCTCTGGTTTTATTTTGCATACGCCATGTTTATAAATAAGACCCCAGGTCATGTGGTATTCTAAAAGAAAACACTGAGCTTCTAGAAATTTGCTCATGACTGTTTTTCAAACGATTTGAGGCTTAATCAGATTATAAAGACCAGACCTCAGCCTGGAAACTGAGCAAAAAGGGCATgaaatcaccaagaggcgacactctagtgcagtttgggaaacagccactagatggcgcggcggctatttttggaatgaaaactccaatagaacgacagcatattataagtctgtaaaataaacgattaaaagtgctgatgattgtga

Function


symbol description
otx5 Enables sequence-specific DNA binding activity. Acts upstream of or within circadian regulation of gene expression and positive regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in forebrain; optic vesicle; and visual system. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Orthologous to human CRX (cone-rod homeobox).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0032922 circadian regulation of gene expression biological_process
GO:0007275 multicellular organism development biological_process
GO:0045893 positive regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030508-1 Enables sequence-specific DNA binding activity. Acts upstream of or within circadian regulation of gene expression and positive regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in forebrain; optic vesicle; and visual system. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Orthologous to human CRX (cone-rod homeobox).

Ensembl:

ensembl_id ENSDARG00000043483

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00017522 True 1747 mRNA 0.50 3 47903864 47909281

Neighbor


gene id symbol gene type direction distance location
XLOC_008856 NA coding upstream 3857 47897252 ~ 47900007 (+)
XLOC_008855 NA coding upstream 20221 47881970 ~ 47883643 (+)
XLOC_008852 CU682604.1 coding upstream 28151 47838836 ~ 47875713 (+)
XLOC_008854 NA coding upstream 45693 47857614 ~ 47858171 (+)
XLOC_008853 NA coding upstream 51513 47850879 ~ 47852351 (+)
XLOC_008858 NA coding downstream 56000 47965281 ~ 47968121 (+)
XLOC_008859 NA coding downstream 83614 47992895 ~ 47993604 (+)
XLOC_008463 BX663520.1 misc upstream 26651582 21252191 ~ 21252282 (+)
XLOC_008851 CU633855.1 non-coding upstream 72448 47828719 ~ 47831416 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000218_00255287_00258751 OTX5, CRX coding CI01000218 null 255287 ~ 259859 (+)
bowfin (Amia calva) AMCG00013664 crx,LOC108443020,LOC107395012,LOC106612616,LOC101485936 coding CM030125.1 CM030125.1 38682999 ~ 38687808 (+)