CI01000034_01718736_01720031 (HOXB13, HOXB13AB, HOXB13A, HOXB13AA)



Basic Information


Item Value
gene id CI01000034_01718736_01720031
gene name HOXB13, HOXB13AB, HOXB13A, HOXB13AA
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information


Item Value
chromosome id CI01000034
NCBI id null
chromosome length 5914002
location 1718606 ~ 1720246 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence


>CI01000034_01718736_01720031.mRNA
ACATTTAACTCGGTCTTGACAAAAAAAAAAAATCTTTGACATTCTTCAGTCAAGGTTTATTTTATGCGTCACGTGGTCCAGCTCTTATCCAATGAAGGCACTGCAGTGCAGACCATAGTCCATTGCGTCAATGCAGCTGTACCAATGTAACTGAGTGTCCTGCTTCGGACTTGAGTCTTTGCAACATAATTTTCCGTCCGAATGGTGAGCGTGCTATGACCACCTCCCTGGTCCTGAATCCTCGCTGGGCGGACACGGTTATGTTTGTGTATGAAAACAACTTGGATGAGCTGAAGAACATGGAGGGTCTGGTTGGAAGCGGCAATTTTGCGGCCAACCAGTGCAGGAATCTGATGGCCCACTCTGCTTTGAGTGGCCACCCGTCTAGCCTCGTCCACGGCTCCAGCTATTCCACTATGGACGTATCGACATCAAGTTCTGCAGAGTCTGGCAAGCAGTGCACACCGTGCCCAACGGTTCCACAGGCCTCGTCCACCGGTCCCATCCCGTACGGCTACTTTGGCAACAGCTATTATCCTTGCAGAATGGGGCGGGGTTCCCTCAAATCCTGTACGCAGCCGAGTGCACTCAGCTACTCTGCAGAAAAATACATGGATACCCCGGTCACATCTGAAGAATATCCTAGCAGGGCTAAAGAGTTCGCCTTTTACCACAGCTACCCCAGTCCCTACCAGTCCATGGCCAGTTATTTGGACGTGTCGGTGGTACAGACGCTTGGAACGGGAGAGCCGCGACACGATAGTCTCCTACCTATGGACAGCTATCAACCTTGGGCTCTGGCTAACGGATGGGGTAGTCAGATGTATTGCTCCAAGGACCAGAGCCAGGCGGGTCATCTCTGGAAGTCTGCGTTAGCAGATGTTGTGGCCCACCAACATGACGGGGGCTCATTCCGTCGAGGTAGAAAGAAGCGGATACCGTACACAAAAGTACAACTCAAGGAACTGGAGAAAGAATATGCAGCCAACAAATTCATCACAAAGGACAAGAGGAGAAAGATTTCAGCGGTAACCAACTTATCCGAGCGTCAAATCACGATTTGGTTTCAGAACAGGAGGGTTAAGGAAAAGAAATTCATTGCCAAAGTTAAGAACAGTGCGCCATAGAGCAAAGCTGAATTAGTGTTTTTCTCGGTGACTTCAAATTAAGGGAAGCAAAAAAGTCATCGCGAGGACGTTTCTTGGACTGGGGGATGAATGTTTTCTTTTCTCAGCGCATTTACACAAAACAAATAAA

Function


symbol description
hoxb13a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in ductal carcinoma in situ and renal cell carcinoma. Orthologous to human HOXB13 (homeobox B13).
hoxb13 Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; methyl-CpG binding activity; and sequence-specific double-stranded DNA binding activity. Involved in angiogenesis and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Implicated in ductal carcinoma in situ and renal cell carcinoma. Biomarker of cervical cancer; endometrial cancer; and prostate cancer.

GO:

id name namespace
GO:0043565 sequence-specific DNA binding molecular_function

KEGG: NA

RNA


RNA id representative length rna type GC content exon number start site end site
CI01000034_01718736_01720031.mRNA True 1257 mRNA 0.49 2 1718606 1720246

Neighbor


gene id symbol gene type direction distance location
CI01000034_01703545_01705527 HOXB10A, HOXD10A, HOXA10 coding downstream 12563 1702892 ~ 1706043 (-)
CI01000034_01694301_01697568 HOXB9, HOXB9AB, HOXB9A coding downstream 20179 1694041 ~ 1698427 (-)
CI01000034_01684215_01687260 HOXB8AB, HOXB8, HOXB8A, HOXB8AA coding downstream 31346 1684177 ~ 1687260 (-)
CI01000034_01680053_01683539 HOXB7A coding downstream 35067 1679589 ~ 1683539 (-)
CI01000034_01675050_01677339 NA coding downstream 39907 1674793 ~ 1678699 (-)
CI01000034_01785791_01788743 NA coding upstream 64989 1785235 ~ 1789815 (-)
CI01000034_01842093_01847705 NR1D1 coding upstream 120691 1840937 ~ 1847705 (-)
CI01000034_01957876_01995623 NA coding upstream 237630 1957876 ~ 1995816 (-)
CI01000034_02010544_02026521 NA coding upstream 289896 2010142 ~ 2026725 (-)
CI01000034_02092229_02092596 GNGT2, GNGT2A coding upstream 371713 2091959 ~ 2092642 (-)
G171704 NA non-coding downstream 7649 1710678 ~ 1710957 (-)
G171631 NA non-coding downstream 316694 1400324 ~ 1401912 (-)
G171582 NA non-coding downstream 470253 1248143 ~ 1248353 (-)
G171572 NA non-coding downstream 520336 1197978 ~ 1198270 (-)
G171405 NA non-coding downstream 590963 1126485 ~ 1127643 (-)
G171712 NA non-coding upstream 20398 1740644 ~ 1741140 (-)
G171724 NA non-coding upstream 44255 1764501 ~ 1768078 (-)
G171731 NA non-coding upstream 60600 1780846 ~ 1781056 (-)
G171751 NA non-coding upstream 107350 1827596 ~ 1830627 (-)
G171785 NA non-coding upstream 133787 1854033 ~ 1855451 (-)
CI01000034_01312431_01312780 PRR15LA other downstream 400352 1311529 ~ 1312780 (-)
CI01000034_01062505_01083413 NA other downstream 641384 1062444 ~ 1083413 (-)
CI01000034_00571856_00577732 NA other downstream 1134323 571856 ~ 577775 (-)
G171229 NA other downstream 1451360 229404 ~ 267246 (-)
G171755 NA other upstream 143872 1864118 ~ 1866373 (-)
G171835 NA other upstream 721575 2441821 ~ 2446293 (-)
CI01000034_02510595_02511512 NA other upstream 789567 2510061 ~ 2511521 (-)
G172016 NA other upstream 1514717 3234963 ~ 3236615 (-)
G172151 NA other upstream 1671267 3391144 ~ 3451802 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_025300 hoxb13a coding NC_007114.7 CM002887.2 23654233 ~ 23655834 (+)
bowfin (Amia calva) AMCG00016669 hoxb13aa,hoxb13ab,hoxb13 coding CM030122.1 CM030122.1 27338007 ~ 27339593 (-)