CI01000043_00372873_00405272 (CACNB2, CACNB2A, CACB2)


Basic Information

Item Value
gene id CI01000043_00372873_00405272
gene name CACNB2, CACNB2A, CACB2
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000043
NCBI id null
chromosome length 7746009
location 372873 ~ 405425 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000043_00372873_00405272.mRNA
GGTTCTGCGGACTCATACACTAGTCGGCCATCGGACTCGGATGTGTCTCTGGAGGAAGATAAAGAGACCTTACGCAGAGAAGCTGAGAGACAGGCTCAGGCTCAGCTCGAAAAGGCCAAGGCTAAACCAGTGGCATTTGCAGTACGTACTAATGTTGGCTACAGCGCCTCCTTTGAAGATGATGTCCCTGTGCCTGGAATGGGAATCTCATTTGAGGCTAAAGATTTCCTTCATGTTAAAGAAAAATTTAATAACGACTGGTGGATTGGTCGCTTGGTGAAGGAAGGGTGTGATATCGGTTTTATCCCAAGTCCAGTGAAGCTTGAAAGCACTCGCATCCACCTGGAGCAACGTGCAAAACAAGGAAAATTTTACTCAAGTAAATCAGGAGCAAACTCTTCATCTAGTTTAGGAGACATGGTTTCAAACTCACGTAAATCAACCCCTCCTTCCTCAGCTGTGGACATAGACGCTGCAGGGTTAGATCCAGAGGAGAGTGACCCTCCTCCCCATCAGCGTTCTCCCAAAGCCAGCCCAAACACAGTAATATCCCCTTTAGCCCGCGAGAAACGAATGCCTTTCTTTAAGAAGACAGAGCATATTCCTCCGTATGATGTGGTGCCCTCTATGAGACCAGTGGTGCTAGTTGGACCCTCCCTCAAGGGCTACGAGGTTACAGATATGATGCAGAAAGCGCTGTTTGACTTTCTGAAGCACCGCTTTGAGGGAAGGATATCAATCACAAGGGTAGCTGCTGATATTTCTCTGGCTAAGCGCTCTGTGCTGAACAACCCCAGTAAACATGCCATCATTGAGCGGTCAAATATACGCTCCAATTTAGCGGAGGTACAGAGTGAGATAGAGAGGATCTTTGAGCTGGCTCGGACATTGCAGCTGGTGGTTCTTGACGCGGACACAATAAACCACCCAGCCCAACTGGGAAAAACTTCTCTTGCACCTATTATTGTCTACATCAAGATCACCTCTCCAAAGGTTTTGCAAAGGTTAATAAAATCTAGAGGGAAGTCCCAGGCAAAACATCTCAATGTACAAATGGTGGCAGCAGACAAACTGGCCCAGTGCCCTTCAGAGCTTTTTGACATAATTCTTGATGAGAATCAGTTGGAAGATGCCTGTGAGCACATGGCTGATTACCTGGAGGCCTACTGGAAGTCCACTCATCCTCCCAGTGTCACTCAGACAAACCCTCTGCTAGAAAAGCTTACCACAGTGGCTGCAGCTGCCGTAGCCTGCAAGGAAACACTGTCTAATCCACAATTAAAGACTCACGAAGATGCGCACTCGCATCCGCATCACCTCGAAGAGGAACTGGACCCTTCGATTCAGCCAAACCATCATCACCATCACCATCATCGCGGGGACAAAGAGAAGGAATATGACCACAATGAGAGGAACTGCCGGCAAAGAGGAAAGCAGAGATCGCAAAGAGAACATCATCACGAGAGGGACAGGAAGCGAGGCGAGGCGGAATGGGCGAGAGAGCATTACATAGAGCAGTGACACAAACACACACACAAATACAACCGTGCCACACACACTCCACTGCTGACCTCTTCCATGGGCTTTGATTGCCTCACGTCAATGTTATGTGTTTTTACAGGATGTAATGTATATGACGTGTATCCATACAAGTTTTTTTCAAGTGTGGACAAA

Function

symbol description
cacnb2a Predicted to enable high voltage-gated calcium channel activity. Acts upstream of or within embryonic heart tube morphogenesis; glial cell development; and retina development in camera-type eye. Predicted to be located in sarcolemma. Predicted to be part of voltage-gated calcium channel complex. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Brugada syndrome 4; hypertension; and hypertrophic cardiomyopathy. Orthologous to human CACNB2 (calcium voltage-gated channel auxiliary subunit beta 2).
cacnb2 Enables voltage-gated calcium channel activity. Contributes to high voltage-gated calcium channel activity and voltage-gated calcium channel activity involved in AV node cell action potential. Involved in calcium ion import; cardiac conduction; and positive regulation of calcium ion transport. Part of L-type voltage-gated calcium channel complex. Implicated in Brugada syndrome 4; hypertension; and hypertrophic cardiomyopathy.

GO:

id name namespace
GO:0003143 embryonic heart tube morphogenesis biological_process

KEGG:

id description
K04863 CACNB2; voltage-dependent calcium channel beta-2

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000043_00372873_00405272.mRNA True 1674 mRNA 0.48 12 372873 405425

Neighbor

gene id symbol gene type direction distance location
CI01000043_00176126_00193756 NA coding upstream 178687 176076 ~ 194186 (+)
CI01000043_00174845_00175959 NA coding upstream 196808 172295 ~ 176065 (+)
CI01000043_00093397_00132783 SIPA1 coding upstream 239400 92844 ~ 133473 (+)
CI01000043_00040385_00051009 RASGRP2 coding upstream 321864 40327 ~ 51009 (+)
CI01000043_00449493_00494730 MYOM1B, MYOM1 coding downstream 44068 449493 ~ 494730 (+)
CI01000043_00529899_00530472 NA coding downstream 124423 529848 ~ 530885 (+)
CI01000043_00613106_00620046 METTL4 coding downstream 207681 613106 ~ 620487 (+)
CI01000043_00670862_00685333 ACER2 coding downstream 264068 669493 ~ 686239 (+)
CI01000043_00700044_00705027 NA coding downstream 293712 699137 ~ 705201 (+)
G189334 NA non-coding upstream 21426 351079 ~ 351447 (+)
G189296 NA non-coding upstream 25466 300804 ~ 347407 (+)
G189245 NA non-coding upstream 137261 234129 ~ 235612 (+)
G189262 NA non-coding upstream 143633 228820 ~ 229240 (+)
G189240 NA non-coding upstream 157164 210439 ~ 215709 (+)
G189340 NA non-coding downstream 8448 413873 ~ 414700 (+)
G189281 NA non-coding downstream 21805 427230 ~ 430719 (+)
G189288 NA non-coding downstream 32078 437503 ~ 438239 (+)
G189289 NA non-coding downstream 120295 525720 ~ 527581 (+)
G189383 NA non-coding downstream 158229 563654 ~ 565387 (+)
G190241 NA other downstream 1278131 1683556 ~ 1692479 (+)
G190272 NA other downstream 2036437 2441862 ~ 2443710 (+)
G191670 NA other downstream 3497808 3903233 ~ 3909966 (+)
G191644 NA other downstream 3902523 4307948 ~ 4350614 (+)
G192454 NA other downstream 4587588 4993013 ~ 4993356 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location