CI01000046_05279865_05281709 (BAXA, BAX)


Basic Information

Item Value
gene id CI01000046_05279865_05281709
gene name BAXA, BAX
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000046
NCBI id null
chromosome length 7063170
location 5279865 ~ 5282127 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000046_05279865_05281709.mRNA
GCATTGGCAATGACCAGATACTTGCTTTGGGTTCTGCACTTCTCAATAACTTCATCTATGAGCGGGTTCGTCGCCATGGAGATGGTGATGCTGAAGTAACCCGGGATCAGTTGGGTGGCGTTGAGCTGTGTGACCCCAGCCATAAACGTCTTGCGCAGTGTTTGCAGCAGATCGGAGATGAGCTGGATGGAAATATGCAGCTGCAAAGGATGTTAAATGACTCTGCTCTTCAACCGACTCAAGATGTCTTCATGCGAGTGGCCCGCGAGATCTTCTCTGATGGGAAGTTCAACTGGGGCAGGGTGGTGGCGCTTTTCTACTTTGCGTGCCGGCTTGTCATCAAGGCTATTTCAACCAAGATTCCTGACATCATTAGAACCATCATTAGCTGGACTATGTCCTACATTCAGGAACATGTTATCAACTGGATCAGGGAACAGGGTGGATGGGAGGGAATCCGCTCTTATTTTGGGACCCCCACATGGCAAACCATCGGGGTTTTCCTGGCAGGAGTTCTCACCACAGTAGTGGTGATCCGCAAGATGTGAGAACGAGGACTGATAAGATGGTGGAGCGTGAGAGAAGAGAGAGTTGAGACAGTGAACAGAGGGTGAAACAGACCAGCAAAGGAGAATGGAAAGATGAGGGGGGAGCAGAAAGGGATTTGGAGTAAAGATATACAGAGAAAGACAAATAAGAGAGTTGAAAATGACATCAACTCACTGAAAGAGATAGTGAAGAGGAGGAAAGAGTGAGAGTCAAGCATGATGCAGATGTCTCGAGCCACTCTTGTTACTCCTGAGCCTGTGCCCTTTCTGATCTACAACTTCTAATATTTGCACTGAAAAATGAGAGATTAATGCGCAAGAGTTCAGGTTTAGGCATAATTTTAGCTATTTATTCTTAGTTATGGGTTATGGGTATCTAGGTTATATAAAAGACTGTACTGGTATTTGATTTAATTTA

Function

symbol description
baxa Predicted to enable channel activity; protein heterodimerization activity; and protein homodimerization activity. Acts upstream of or within several processes, including positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to cadmium ion; and response to methylmercury. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including digestive system; female organism; heart; immune system; and male organism. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Orthologous to human BAX (BCL2 associated X, apoptosis regulator).
bax Enables several functions, including BH3 domain binding activity; channel activity; and protein dimerization activity. Involved in several processes, including apoptotic signaling pathway; mitochondrion organization; and positive regulation of apoptotic process. Located in several cellular components, including endoplasmic reticulum membrane; mitochondrial outer membrane; and nuclear envelope. Part of BAK complex; BAX complex; and mitochondrial permeability transition pore complex. Colocalizes with cell periphery. Implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Biomarker of several diseases, including osteoarthritis; reproductive organ cancer (multiple); stomach cancer; teratoma; and urinary system cancer (multiple).

GO:

id name namespace
GO:0005741 mitochondrial outer membrane cellular_component

KEGG:

id description
K02159 BAX; apoptosis regulator BAX

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000046_05279865_05281709.mRNA True 966 mRNA 0.46 5 5279865 5282127

Neighbor

gene id symbol gene type direction distance location
CI01000046_04861221_04879259 MPP3A, MPP3 coding upstream 399196 4861221 ~ 4880669 (+)
CI01000046_04841558_04852685 NA coding upstream 426689 4841558 ~ 4853176 (+)
CI01000046_04811748_04819011 ZNF281A coding upstream 460497 4811610 ~ 4819368 (+)
CI01000046_04806234_04808207 NA coding upstream 471530 4805355 ~ 4808335 (+)
CI01000046_04694468_04701075 NA coding upstream 578612 4693655 ~ 4701253 (+)
CI01000046_05305482_05310465 NA coding downstream 23066 5305193 ~ 5310479 (+)
CI01000046_05315583_05316990 NA coding downstream 33058 5315185 ~ 5317089 (+)
CI01000046_05335886_05341205 GPATCH8 coding downstream 53759 5335886 ~ 5341888 (+)
CI01000046_05392316_05401559 ARF3A, ARF2B, ARF1L, ARF3, ARF2, ARF1, ARF3.S, ARF5, ARF2A, ARF5.L coding downstream 109856 5391983 ~ 5402075 (+)
CI01000046_05481838_05537970 NA coding downstream 199711 5481838 ~ 5538151 (+)
G197352 NA non-coding upstream 3412 5259318 ~ 5276453 (+)
G197393 NA non-coding upstream 23083 5249761 ~ 5256782 (+)
G197457 NA non-coding upstream 31283 5248350 ~ 5248582 (+)
G197456 NA non-coding upstream 32101 5247299 ~ 5247764 (+)
G197455 NA non-coding upstream 32612 5247045 ~ 5247253 (+)
G197391 NA non-coding downstream 6874 5289001 ~ 5326198 (+)
G197372 NA non-coding downstream 9844 5291971 ~ 5294407 (+)
G197383 NA non-coding downstream 98994 5381121 ~ 5384299 (+)
G197399 NA non-coding downstream 104343 5386470 ~ 5386716 (+)
G197466 NA non-coding downstream 108995 5391122 ~ 5391352 (+)
G196869 NA other upstream 858178 4415530 ~ 4421687 (+)
G197121 NA other upstream 908435 4371011 ~ 4371430 (+)
G197055 NA other upstream 1130085 4149423 ~ 4149780 (+)
CI01000046_03943890_03945302 ATP5J2 other upstream 1334365 3943794 ~ 3945500 (+)
G197528 NA other downstream 443994 5726121 ~ 5742684 (+)
CI01000046_06808895_06820945 GSPT1, ERF3B, GSPT1L other downstream 1537811 6808507 ~ 6821543 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location