XLOC_009386 (crppa)



Basic Information


Item Value
gene id XLOC_009386
gene name crppa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 34495056 ~ 34568705 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00018457
TTCATGCGCGCGCTTAAGGAGCGTCATAATAACGGTAACAATTCAGTTGTCTTGTCTCCGTCACATTCGCAAACTTTGCTTTTCTTGTCCATGGGAGGGCAGACGTCTCTTCAAAATGCTGTTACAGTTCCACCACGAGACGCAAAGGCCCTTGGACCCCGGGTGTCTCCTACCACAAGACGCCGAGCGGAGCGCCGACCAACCCGGGCGCGCGGTGGTGGATTTCCCGGTAGCTGCCGTTCTGCCCGCCGGAGGCTCCGGGGAGAGGATGGGACTGACCACACCGAAACAATTCTGCTCCATCTTTAACAGACCTCTGATAAGCTACACCATTCAAGCATTTGAGAGATTACCGTGGATCGTAATGGTTGTCGTTGTGGTTGCTAAGGATAATCATGACCTGATGCTGAATATTGTCCGAAAATTTAATCACACAAAGGTAAAAGTAGTCCACGGGGGTACCACCAGACACCGGTCCATCTACAACGGTCTTCAGGCCTTCAGCGACTCTACAGACTCATCGACACCCAAACCAAAAGTGGTCATCATACATGATGCAGTACGGCCATTTGTGGAAGAAGATCTTCTGCTGAAAATCACCCTAGCAGCTAAAGAACAAGggGCCTCAGGAGCGATTCGTCCTCTTGTGTCAACGGTCATTGCAACCACGTCAGAAAGTTACCTGGACCACTCGCTGGAGAGAGCCAAGTACCGGGCCAGTGAAATGCCTCAAGGATTTCTTTATGACATTATTTTCCAAGCCTACCAGCGGTGCAGTGAATTTGACTTAGAGTTTGGCACCGAGTGTCTACATTTGGCCCTGCAGTACTGTGGCACGAATGCCAGGCTCATAGAGGGACCACCGACTCTGTGGAAAGTAACATACAAGCGAGATCTAGCAGCTGCAGAGGCTATTATTAAAGAGACTCTTTCGGTGTCAGCCTGTATCATCGCAGAAGCTGAAGAAGAAGCTGTTGAGTTGGCCAAAACCCTTCAGAAAAATCTGAACATGatgGAGACAGACGTCATTCCATGTGGAAAGGAGAGCAATGTGCAGTACCTGTCCAAAACCCGAAACTTTATTCACATATCTGCGAGTGCATCAAGCTCCTTGTGGGTGctggaaatggtgaaatgttTTGAAGACATCGACCATGCTCGTTTATACCCAGTAGTTATTGTTTGGGTACAGCTGAGCATGACAAAGCAGTCGGCTGACAGCCAAGAAACAGACGAGTTCATGGCTCTGGCCTCAGAAGTCAAACAGCGAAACGTTCTGCTCTATGGAATTAAGATCGATCACTCAAAGGAGCTGGAGCAATGGCAGAGATCACTGGAGAGACTCGGTCAGATCACACTCGTCCTCATCAGAGACAGAAACATGGCTCTCACTGGACAGATGCTTCATGTCTGAACACCAGCAGAAGCAAGCACAGCAGCTTACCATATCAGCACTGAAACAACATCTCACAGATATTCAGCCTTTTCAGTATGAAATAAACGACAGACTGTGAGTGATGGTGGTGAGGTCAGACCCTCAGCATTTGGATTGAAAGCTTGATTGTGTTTCTTTAGATTGCAAGGTAAGCGGTTTCAAATGCAAAGCTAGTTTCAAGACCAATTAAAACACTACACTGAATCTTTGACCATCTTTATATGTGAAAAATGAAtgttgtttaataaaacaaagttaTTGCTCTGC
>TCONS_00018458
AATTGATAAACCCTGTCGAAATGAGTCAAATGCCCACATTTGACACACGTTAACGTCAGAccgtgatttttttaaattgaatattACTTGAATAAACAGTAAACGATTCTTTGCGAAGTGCGATAGTTCAGACCGCCACAGCTGCTGCGGTCCCATGATGGGTGCTGGACAGGCAGCGTCTGATAGAGTTACCGGGGAAAGCTGCAACATTACCGCCACAAACTCCGTTTCACCCCCACCAATCACGCAGAATGCAGGTTAACAGGTTCTTCACATGAATACGGCTGCCACAAATGCGGAGTTAATTGAAACCAAGGAAAAAATGCAGCAAGAGCGCTGTTCTTCCTCCGACAGGCCCTTGGACCCCGGGTGTCTCCTACCACAAGACGCCGAGCGGAGCGCCGACCAACCCGGGCGCGCGGTGGTGGATTTCCCGGTAGCTGCCGTTCTGCCCGCCGGAGGCTCCGGGGAGAGGATGGGACTGACCACACCGAAACAATTCTGCTCCATCTTTAACAGACCTCTGATAAGCTACACCATTCAAGCATTTGAGAGATTACCGTGGATCGTAATGGTTGTCGTTGTGGTTGCTAAGGATAATCATGACCTGATGCTGAATATTGTCCGAAAATTTAATCACACAAAGGTAAAAGTAGTCCACGGGGGTACCACCAGACACCGGTCCATCTACAACGGTCTTCAGGCCTTCAGCGACTCTACAGACTCATCGACACCCAAACCAAAAGTGGTCATCATACATGATGCAGTACGGCCATTTGTGGAAGAAGATCTTCTGCTGAAAATCACCCTAGCAGCTAAAGAACAAGggGCCTCAGGAGCGATTCGTCCTCTTGTGTCAACGGTCATTGCAACCACGTCAGAAAGTTACCTGGACCACTCGCTGGAGAGAGCCAAGTACCGGGCCAGTGAAATGCCTCAAGGATTTCTTTATGACATTATTTTCCAAGCCTACCAGCGGTGCAGTGAATTTGACTTAGAGTTTGGCACCGAGTGTCTACATTTGGCCCTGCAGTACTGTGGCACGAATGCCAGGCTCATAGAGGGACCACCGACTCTGTGGAAAGTAACATACAAGCGAGATCTAGCAGCTGCAGAGGCTATTATTAAAGAGACTCTTTCGGTGTCAGCCTGTATCATCGCAGAAGCTGAAGAAGAAGCTGTTGAGTTGGCCAAAACCCTTCAGAAAAATCTGAACATGatgGAGACAGACGTCATTCCATGTGGAAAGGAGAGCAATGTGCAGTACCTGTCCAAAACCCGAAACTTTATTCACATATCTGCGAGTGCATCAAGCTCCTTGTGGGTGctggaaatggtgaaatgttTTGAAGACATCGACCATGCTCGTTTATACCCAGTAGTTATTGTTTGGGTACAGCTGAGCATGACAAAGCAGTCGGCTGACAGCCAAGAAACAGACGAGTTCATGGCTCTGGCCTCAGAAGTCAAACAGCGAAACGTTCTGCTCTATGGAATTAAGATCGATCACTCAAAGGAGCTGGAGCAATGGCAGAGATCACTGGAGAGACTCGGTCAGATCACACTCGTCCTCATCAGAGACAGAAACATGGCTCTCACTGGACAGATGCTTCATGTCTGAACACCAGCAGAAGCAAGCACAGCAGCTTACCATATCAGCACTGAAACAACATCTCACAGATATTCAGCCTTTTCAGTATGAAATAAACGACAGACTGTGAGTGATGGTGGTGAGGTCAGACCCTCAGCATTTGGATTGAAAGCTTGATTGTGTTTCTTTAGATTGCAAGGTAAGCGGTTTCAAATGCAAAGCTAGTTTCAAGACCAATTAAAACACTACACTGAATCTTTGACCATCTTTATATGTGAAAAATGAAtgttgtttaataaaacaaagttaTTGCTC

Function


symbol description
crppa Predicted to enable D-ribitol-5-phosphate cytidylyltransferase activity and protein homodimerization activity. Involved in protein O-linked mannosylation. Acts upstream of or within brain morphogenesis; muscle cell development; and regulation of protein glycosylation. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Used to study Walker-Warburg syndrome. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2U and congenital muscular dystrophy-dystroglycanopathy A7. Orthologous to human CRPPA (CDP-L-ribitol pyrophosphorylase A).

GO:

id name namespace
GO:0048747 muscle fiber development biological_process
GO:0035269 protein O-linked mannosylation biological_process
GO:0048854 brain morphogenesis biological_process
GO:0008299 isoprenoid biosynthetic process biological_process
GO:0060049 regulation of protein glycosylation biological_process
GO:0005829 cytosol cellular_component
GO:0005737 cytoplasm cellular_component
GO:0047349 D-ribitol-5-phosphate cytidylyltransferase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0016779 nucleotidyltransferase activity molecular_function
GO:0070567 cytidylyltransferase activity molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-061110-16 Predicted to enable D-ribitol-5-phosphate cytidylyltransferase activity and protein homodimerization activity. Involved in protein O-linked mannosylation. Acts upstream of or within brain morphogenesis; muscle cell development; and regulation of protein glycosylation. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Used to study Walker-Warburg syndrome. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2U and congenital muscular dystrophy-dystroglycanopathy A7. Orthologous to human CRPPA (CDP-L-ribitol pyrophosphorylase A).

Ensembl:

ensembl_id ENSDARG00000005034

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00018457 False 1702 mRNA 0.47 11 34495056 34568705
TCONS_00018458 True 1906 mRNA 0.47 10 34495059 34558579

Neighbor


gene id symbol gene type direction distance location
XLOC_009385 meox2a coding downstream 16608 34428308 ~ 34478448 (-)
XLOC_009384 agmo coding downstream 76531 34334722 ~ 34418525 (-)
XLOC_009382 dgkb coding downstream 168595 34215796 ~ 34326461 (-)
XLOC_009383 FP017158.1 coding downstream 215521 34279421 ~ 34279535 (-)
XLOC_009381 etv1 coding downstream 280616 34172371 ~ 34214440 (-)
XLOC_009388 ankmy2a coding upstream 4606 34573311 ~ 34590820 (-)
XLOC_009389 NA coding upstream 33817 34602522 ~ 34607406 (-)
XLOC_009390 bag6 coding upstream 49655 34618360 ~ 34668485 (-)
XLOC_009391 gabbr1a coding upstream 148809 34717514 ~ 34845414 (-)
XLOC_009392 sh3bp5la coding upstream 285320 34854025 ~ 34866219 (-)
XLOC_009376 CR855379.2 non-coding downstream 607389 33868661 ~ 33887667 (-)
XLOC_009377 NA non-coding downstream 617725 33869579 ~ 33877331 (-)
XLOC_009371 NA non-coding downstream 813378 33665924 ~ 33681678 (-)
XLOC_009370 CT027778.1 non-coding downstream 831884 33663055 ~ 33663172 (-)
XLOC_009404 CR848683.2 non-coding upstream 845761 35414466 ~ 35661368 (-)
XLOC_009405 CR848683.1 non-coding upstream 872035 35440740 ~ 35468800 (-)
XLOC_009406 NA non-coding upstream 1045529 35614234 ~ 35675985 (-)
XLOC_009407 NA non-coding upstream 1192976 35761681 ~ 35886373 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000095_02282657_02292145 ISPD coding CI01000095 null 2282156 ~ 2292145 (-)