XLOC_009591 (cdkal1)



Basic Information


Item Value
gene id XLOC_009591
gene name cdkal1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 39498 ~ 53136 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00019288
cAGGAGATGTCCCGTATCCTGCAGCACCCGCGCGTCTTCTCCTTCCTGCATGTGCCGCTGCAGTCTGCGTCTGACAGTGTGCTGATGGAGATGCGGAGGGAGTACTGCTGCGCCGACTTCACACACCTGGTGGACTACCTGAAGGAGAGGGTTCCAGGCATCACCATAGCGACAGACATCATTTGTGGTTTCCCGGGAGAGACGGATGAGGACTTCGAGCAGACGCTGGCGCTGGTGCGGCGCTACCGCTTCCCCAGCCTGTTCATCAACCAGTTCTACCCGCGACCGGGCACCCCGGCGGCCCTGATGCAGCAGCTGCCCGCGCACGTGAAGAAACAAAGAACCAAAGAACTGTCGGCGCTCTTCCACTCCTACAGGCCCTACGACCACAAGATGGGCGAGCAGCAGCAGGTTCTGGTCACTGAGGAGTCCTTTGATTCGCAGTATTACGTCGCACACAACAAGTTCTATGAGCAGgtgctggTGCCCAAGCGGCCTGAGTATCTGGGTAAGATGGTCCAGGTGGAGGTGTACGAGTGCGGGAAACACTACATGAAGGGCCGACCACTGGAGGAGGCGCCACTGCGCACCGCATACACCACTGCACCACTGCTGAAGGGACAGGTGTCGGGACACACacagGCCGGTGTGTGTGAGCCGCAGTGCTGGATGCCGGACGGGATGAGGATTCTGGCTGTGGTTCTGCTTCTGTCTGCGGTTCTGCTGGCGTTACTGATGGAGAAACTGCTCTGATCATCCTCCGGGACTCCTCTGCTCCGGCTCTGGTGAAGCGGCACCAGTAGAGACTGGTCTTTTAACCGTGGACTGAAGACTCTGCTTCAGGGTTTATTTTAGCGTGTGGAGCGGCTGTGCTgcggctgtgtttgtgtgttctgtttaAGCCCGCtcctcttttcttcttcttcttcttctgttgtCTCGGGCTGGGTCTGGCTGTGCTCTGAGCTCCAGACTCGGCCTGGTTTTGTTCTCCACATAAAGCGGTTTAATAAAGCAGTCTCGGTCTCCTGC

Function


symbol description
cdkal1 Predicted to enable N6-threonylcarbomyladenosine methylthiotransferase activity. Acts upstream of or within pancreas regeneration and type B pancreatic cell development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in diabetes mellitus; gestational diabetes; and type 2 diabetes mellitus. Orthologous to human CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1).

GO:

id name namespace
GO:0031018 endocrine pancreas development biological_process
GO:0006400 tRNA modification biological_process
GO:0035600 tRNA methylthiolation biological_process
GO:1990798 pancreas regeneration biological_process
GO:0008033 tRNA processing biological_process
GO:0003323 type B pancreatic cell development biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016740 transferase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0061712 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase molecular_function
GO:0035596 methylthiotransferase activity molecular_function
GO:0035598 N6-threonylcarbomyladenosine methylthiotransferase activity molecular_function
GO:0051536 iron-sulfur cluster binding molecular_function
GO:0051539 4 iron, 4 sulfur cluster binding molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko03016 Transfer RNA biogenesis

ZFIN:

id description
ZDB-GENE-040426-1443 Predicted to enable N6-threonylcarbomyladenosine methylthiotransferase activity. Acts upstream of or within pancreas regeneration and type B pancreatic cell development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in diabetes mellitus; gestational diabetes; and type 2 diabetes mellitus. Orthologous to human CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1).

Ensembl:

ensembl_id ENSDARG00000104848

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00019288 True 1032 mRNA 0.58 6 39498 53136

Neighbor


gene id symbol gene type direction distance location
XLOC_009590 CABZ01090785.1 coding upstream 35253 1471 ~ 4245 (+)
XLOC_009592 sox4b coding downstream 14933 68069 ~ 71108 (+)
XLOC_009593 NA coding downstream 67888 121024 ~ 122041 (+)
XLOC_009594 NA coding downstream 74299 127435 ~ 129026 (+)
XLOC_009595 si:ch211-201o1.1 coding downstream 99046 152182 ~ 168150 (+)
XLOC_009596 NA coding downstream 133438 186574 ~ 190975 (+)
XLOC_009598 LO017841.1 non-coding downstream 366986 420122 ~ 513158 (+)
XLOC_009599 NA non-coding downstream 379834 432970 ~ 457475 (+)

Expression



Co-expression Network