XLOC_000096 (smcr8b)


Basic Information

Item Value
gene id XLOC_000096
gene name smcr8b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 8534698 ~ 8540050 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000189
ACATACTTGGGTTCATCTCATGttgaattttaaatatattttcactgTTTGTAGTTCTGTAACAAGTCAGTcaagaatgtttatttatttatttatttatttaaaaagtaataatttaaatgttctttaaatGCTGCTGATTAATCAATAAAGACATTAACAGTCTTGCTGAAGACTTTGAGGtagttaaatatataataattatatgtttACACAGTCCTCATACCTTTACCTGAATATCATTTCATAATACTTTTCACACCCTTGTCTGGTTTGTTAAAAACAATTCGTGCCACTATGATTGGGTCTCCAGACTTGGTAGCTTTCACCAAAGAAACAGATTTCAGTGAAATAACCACAGACTCTTCGGTACTTCCAGAGGATCTGTCTGTGCCCATGTATCCATACACTGGGGATGCCACCCCATGGTCCAAGATATCTAGTGCCAAGTTAAAGAAAGATTTCATCCTCATATCAGAGTTTTCAGAGCAAGTTGGCCCCCAGCCATTACTTACAGTTCCTCTTGAAACTAAAGCTTGTGGGACTTTTGATTTGAACTACTTCTCTCTTCGGATCATGTCAGTGGACTATCAGACTTCCCTGGCCGGCTCTCCAGGTTACGGTTCCTTCAAGCTGAACTTTGTAGAAGACTCAAAGGTGGTTTTAGCAGACTCAAGAGAAGGAGTATTTGCATATGTGCACCACCTGACCCTCTATGACCTGGAGGCTCGAGGTTTTGTGCGGCCTCTTTGTCTTGCCTATGTGTCGTCTGATGAAAATAAAATCATTCAACAATTCCAAAGGATTTCCACAGAATTCAACAAAGTCTCAGAATGTCTGAAAACTGGAAACAGGAAGAACTTTGCGAATGAACTGGAGGTAAAGCTTAGAGATTTGGAGTATACAAGAGTCGTGTTACAGAAAGAGTTAAATACTGTGTCTGTAAAGTGCAGCAGTGAAAGGGAACCAATATTAAATGGTGTACATTCATTTGAGAGGAATGCAGATGAGGTGAAACTGAACGAGAAATCCTCTCACACAGATGAAATCTCACCGCAAGAGAAAGACGGATGTGGGAATTCTAGAAAGGTGGAAGTGAAGCTTGAAAATGAGAATAGGTCACATTTTGAACTTGAACAGTACGGGAAACAAAGAAAGGACAAACCGGATAAAACATCATGTCCAATGCCTTTGGCTAACAAAAATGATGAGTTGGCCAGTGTAGAAAAACTGATTCAAGACTATAAAAGCCTTCTAAAGCAGGTCACTTGTTACCCAACTAGAAAGCTTAGAGACTCTGAATACTCCCCTTATGAACCTGATGACCTCCCTCAGTCTTTTGACCTCGACCTGGACAGTCAGTTTTCCGGGCCAATGCTAGAATGCAGTGTTTTTACTTATACAAACACACCCTCACAAACTCTGCAGCAGATTAACTCCACGTCATCCAGCCGATTTGACAAGCGTCTGAAAACTCTCGAGGAATTGTGTGATGACTACTTCTACCAACAAGCACTGCAGCAACTGTACTCTATCGAGAGAACGTTCAGAGGTGACGCCTGCTATCTCTACACTCAACAACTCTGCCGAAATCTCCTCCGCAACCTCAAATCTACTAATTTCTTGTTTGAGGATCTGTGCGACCTGAACGATGATGTAGGGTTACAGATTGGGCAAAGCACAATCCAGCAAACATCCTTTCTTCCTGCACCCTCATTTCTAAGTGGACCGGTCAGTCTTGAGTCATACGCATCTTGTGTTGAAATGGTGCCAATAAAACTTGAGTTGGGTGGATCCAGCCAATCTCAAGTTCAACATAGCACTTTAAATACACCTTCAGAGGACAACCGACCCCAAGTAGCAGACAAATCCCCAGCAGAGGTTGAGATGAAAGATGAGATCATTTCAGCTCCAGATTGTCAAGGAAATGTGGAAAGTGTCTCGAATTTGATGAAAACCAGTATTAGTAGTGGAGACAGTATTGAGGTGTTGGGAACAGAGAGGTCATTTAGATCCCAGGGGGCAAATACGCCAGTGGAAACAGCAATGCACAGACCTCCACCTTTGTCTAGTGCCACTGCACTGGAAGGTCTAAAGCAAGGAAGGGTGCCTACCAGACGAACATGCAGTGAAGACAGCATTGAGGTGCTTTGCATAACAGAATCCATCTTACCTGATGAACTGCGTGCCTCATACCCCTGCGCAATTGATGAAGAAAGCCCAGAGCAAGAGACTGATGAGAAAAACTCGTCTCAATATCAAGAAGACAACAATGAAAAGAGTATATATGTTCAGGGAAAGATCTCTGCAGATCATGAAAATGCATGTTTGAAAAAGCTACATCCATCAGTCACTGTAACCCCACCAGACTGCCCTTTGACTCTAGAAGAAACAAGCTTTCAAGACTCTTGTCAAGCAACAGAATCAGCCACTATGTTGTTGTTAGATGAGCCCAGCCGGATGGTACCTGACGATTTATCAGACTGCTTCAGCTATCGGAGCACCACTGCATCCACGACCTCCGAATGCACTTTCCCTGCGTGTCTTCCCAAGGACAAAAGAGAAGGTGGGACCAGACGGAGACGAGGCAGAGTAGGAAGAGCAGCACTTCAGTTCATGCGGCAGTTTCCCTTTGCAGTGCATGCAGTGTTTAGCCTTCTAAGTGGCCGAACATTGGTGGTACTAGGAAGTGAGGAGGCTGCTGTGAGACGACTAGTTACAGCACTGTCCGTGTACCTGCCACATCTGACTAAATACAAAGACAGCATCCAGCCTTGGACTTCAACACCACTGCAGCTTACGGACCTGCTCAACTGGAAACTCATTGGTTTTGACAGGATGTGCAGTTTTAATCCCTCAAGTCTGCCTCACTGCCTGGACCATTACAGCCGGTACCTCAGTATCCTAGATGTAGATCAAAAAACCCTGCACTGCCCGACCTACAGTGGTTCTCTCATCAACCTGCTGGTGGAACCCAAGAGCCACTTTAAACGTGGAAACACCTACTTCACATTCGCTCAAAGTGTGCAAAGCAAGCTCGTCACCAAAGCATTCCTCTTAACATTCTCACATGGTCACCCTTCACCCAGCAGGCCCCAGGGAAGCTCAGGGACAGAATGTTTTCTTTCTGAACTTCACACTGATGACAAGAAAATCCTTCGCTATTTATCTGAACTCATCAAACTGCACTTCATGGAGGTTACTCCCAATGTGCTCCTATTCAGCTACACCACAACATCCATCTTCAAACTGTGAAAGTCATTCACAAAAACTACTCAAAGATTTGTGCAATGTAGTGTTGTAATACTTGGCTTTGACTGCAGACACAAAGCTGTGTTGCTCAGCTTTAACATTATATTTACAGTTTCTGCATGTTGTGATATCTTGTTTACAAAAGGCACTTATACAGTAATTATGGCTTAATTGCTTGTGAAAAGTTCCCTGAGAATTGCAATCATTCACAAGCTTAAATGAGCTACTGTATAACAAAGCAATATTGAACAGCTCTGTATCAGTTGCATTTGAATCttaactatttatttacaataccacTAATGTTTAAAGACTTGAAACTCTGTTTGCTGAATATAACTGTGCAAATAACAAAATCAGCCTTATTAAaaagtataagaaataaaaaattgatCTTAACTACAATAAAA

Function

symbol description
smcr8b Predicted to enable protein kinase inhibitor activity. Predicted to be involved in negative regulation of macromolecule metabolic process; regulation of TOR signaling; and regulation of macroautophagy. Predicted to act upstream of or within autophagy. Predicted to be located in cytoplasm. Predicted to be part of guanyl-nucleotide exchange factor complex. Orthologous to human SMCR8 (SMCR8-C9orf72 complex subunit).

GO:

id name namespace
GO:0010629 negative regulation of gene expression biological_process
GO:0006914 autophagy biological_process
GO:1903432 regulation of TORC1 signaling biological_process
GO:1902902 negative regulation of autophagosome assembly biological_process
GO:1901098 positive regulation of autophagosome maturation biological_process
GO:0032008 positive regulation of TOR signaling biological_process
GO:0032045 guanyl-nucleotide exchange factor complex cellular_component
GO:0005634 nucleus cellular_component
GO:1990316 Atg1/ULK1 kinase complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function
GO:0004860 protein kinase inhibitor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-061122-1 Predicted to enable protein kinase inhibitor activity. Predicted to be involved in negative regulation of macromolecule metabolic process; regulation of TOR signaling; and regulation of macroautophagy. Predicted to act upstream of or within autophagy. Predicted to be located in cytoplasm. Predicted to be part of guanyl-nucleotide exchange factor complex. Orthologous to human SMCR8 (SMCR8-C9orf72 complex subunit).

Ensembl:

ensembl_id ENSDARG00000015803

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000189 True 3662 mRNA 0.42 2 8534698 8540050

Neighbor

gene id symbol gene type direction distance location
XLOC_000095 mief2 coding upstream 2689 8521323 ~ 8532009 (+)
XLOC_000094 alkbh5 coding upstream 18103 8508753 ~ 8516595 (+)
XLOC_000093 myo15ab coding upstream 27468 8442071 ~ 8507230 (+)
XLOC_000092 cacna1hb coding upstream 130693 8304904 ~ 8404005 (+)
XLOC_000091 SLC5A10 coding upstream 371531 8110562 ~ 8163167 (+)
XLOC_000097 NA coding downstream 33727 8573777 ~ 8575057 (+)
XLOC_000098 AL928650.2 coding downstream 35257 8575307 ~ 8577274 (+)
XLOC_000099 AL928650.4 coding downstream 39147 8579197 ~ 8586066 (+)
XLOC_000100 NA coding downstream 47180 8587230 ~ 8590636 (+)
XLOC_000101 si:ch211-160d14.15 coding downstream 53510 8593560 ~ 8597015 (+)
XLOC_000087 NA non-coding upstream 860469 7672121 ~ 7674229 (+)
XLOC_000084 NA non-coding upstream 1021936 7512529 ~ 7512762 (+)
XLOC_000082 CABZ01075319.1 non-coding upstream 1418784 7092273 ~ 7115914 (+)
XLOC_000081 CU929161.1 non-coding upstream 1470755 7063837 ~ 7063943 (+)
XLOC_000080 NA non-coding upstream 1544671 6956913 ~ 6990027 (+)
XLOC_000105 NA non-coding downstream 410824 8950874 ~ 8965939 (+)
XLOC_000106 NA non-coding downstream 427429 8967479 ~ 8976422 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000300_00390712_00395191 NA coding CI01000300 null 390611 ~ 395743 (+)