CI01000051_07470914_07489207 (LRP1AB, LRP1)


Basic Information

Item Value
gene id CI01000051_07470914_07489207
gene name LRP1AB, LRP1
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000051
NCBI id null
chromosome length 8436717
location 7470914 ~ 7489242 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000051_07470914_07489207.mRNA
AGGAGGAACCATTCCTTATCTTTGCGAACCGTTATTACCTGCGAAAACTCAACTTGGATGGCTCTAACTACACATTGATTAAACAGGGGCTCAATAACGCAGTGGCTCTGGACTATCATTACGCAGAGCAGATGATCTACTGGACAGACGTGACCACACAAGGCAGCATGATCCGTCGCATGAACATCAACGGCAGTAACGTGCAGGTGCTGCACAGAACCTCTCTGAGCAACCCTGACGGTCTCGCCGTGGACTGGGTTGGGGGAAACCTGTACTGGTGTGATAAGGGCAGAGACACAATTGAGGTATCCAAGCTGAACGGAGCTTACAGAAGTGTGCTGGTCAACAGCGGCCTGCGGGAGCCTAGAGCTGTGGCTGTGGATGTGAGGAATGGGTATCTGTATTGGTCAGACTGGGGTGACGTGCCACATATTGGCCGCATCGGCATGGATGGCACAGATCGTCACATCATCATTCAGGATAAGATCACATGGCCTAACGGCTTGACACTAGATTTTATTAATGACCGCATCTACTGGGCAGACGCTCGTGAAGACTACATTGCTTTTGCCAGCCTGGACGGATCCAACAGACACATTGTGCTGAATCATGACATCCCTCACATCTTTGCCATGACTCTGTTTGAGGAGTACATCTACTGGACCGACTGGGAGACCAAGTCCATCAACAGAGCTCACAAAACACTGGGCACCAACAAAACCATGTTGATCAGCACTCTGCACAGACCCATGGACATACACATCTATCATCCCTCCAGACAACCTGAGGTGTCAGGTCACCCGTGTCAGGAGGATAATGGTGGCTGCAGTAACCTGTGTTTGCTCTCTCCTGGAGGAGGCTACAAGTGTGCCTGTCCCACCAACTTCTATCTGGCTGCTGATGGAAAACAGTGCCTGTCCAACTGTACTGCCAGCCAGTTTGTCTGCAAGAATGATAAGTGCATTCCTTTCTGGTGGAAGTGTGATACTGAAGATGACTGCGGAGACCGCTCGGATGAGCCTGCTGATTGTCCTGAGTTTAAATGCAGACCAGGCCAGTTCCAGTGTGGCACGGGTCTCTGCACCAATCCAGCTTACATCTGTGATGGAGACAATGACTGCCAGGACAACTCTGATGAAGCCAACTGTGACATCCATGTTTGCCTGCCCAGTCAGTTTAAGTGCTCGCATCCAAGTCGCTGTATCCCTGGAATCTTGCGCTGTAACGGTCAGAACAACTGCGGCCAGGGAGAAGATGAGAAGGACTGTCCTGAGGTGACCTGTGCTCCTAACCAGTTCCAGTGTGCCATCACTAAACGCTGTATACCACGAGTCTGGGTGTGCGATAGAGACTACGACTGCGTTGATGAATCCGACGAACCAGCCAACTGCACTCAAATGAAGTGCGGTGTGGACGAGTTCCGCTGTAAGGACTCAGGCCGCTGTATCCCATCTCGCTGGACGTGTGATGGAGAGGACGACTGTGGCGACGCCTCAGATGAGCCCAAAGAGGAGTGCGATGAGAGAACATGTGAGCCATACCAATTCCGCTGCAAGAACAACCGCTGTGTGCCGGGCCGCTGGCAGTGTGACTATGACAATGACTGTGGCGATAACTCAGATGAGGAAAAGTGCGTGCCGCGTCAGTGCTCTGAGAGCGAGTTTGCCTGCAGTAATGGCCGTTGTATTGCTGGGAGGTGGAAGTGTGATGGAGATCATGACTGTTCAGATGGATCTGATGAGCACGGCTGTGATCTGAAGTGTGAGGAGGATCAGTTCCAGTGTAAGAACGGTCACTGTATCCCGCTCCGCTGGCGTTGTGACGCAGATGCTGACTGCATTGATGGCAGTGATGAAGAGAGTTGTGACATTTCTGTGGCACGGCACTGCCCCCAGGATGAGTTCCAGTGTAATAACACTCTGTGTAAACCACTGTCCTGGAAGTGTGATGGGGAGGATGACTGTGGCGATAACTCTGATGAGAACCCTGAGGAGTGCAGAAACTTCCAGTGCCCACCCACTAGAAATTTCCGTTGTCTGAATAATCGTGTCTGTCTCTGGAGTGGTAAGCGCTGCGATGGTGTGGACAACTGTGGGGACAATTCAGATGAGACTAACTGTGGAGACCACACATCCACATGCGATAAAGACCAGTTCAAGTGCAGCAATGGCAAATGCATCAGCGCAAACCTGCGGTGCAACTTCTTCAACGACTGTGAAGATTACGGCTCAGATGAGATCGGCTGCAAGACAGACACCATGCTAAATGACTGCAAGAGTAACAAATCTTTATGTGGAGATGGTGATGAGGCTCACTGTGTTTCCAACGGCACGGACACGTTCTGCTCCTGCAAACATGGTTTCCAGAGCGTTGGACACAACACCTGTGAAGATAAGAATGAGTGCAAGCAGTTTGGTATATGTTCTCACATATGTAACAACACCAAGGGCTCCTACAAGTGCAGCTGCCACAAATACTTCACCAGGATTAACCACACATGCAAGGCTGATGGTTTGACAAATAACCAACAGGTGCTCTACATTGCGGATGACAATGAGATCCGCAGTCTAAATCCTGGGATGGTTTACGAGCAGACATTCCAGGGCGACGCAAACGTGCGCATCGATGCCATGGACTTGCACGTCAAGACCAATCGCATTTACTGGACCAACTGGCACACCTCTGGCATTTCCTGCTTCCAGCTGCCTGCTCCATCCTCATCATCAGGTCCTACTTCCAACTCTCACCGCAACACGAGGCAAAGCGAGGGCAGCATCACCAACCTAGATATTTCAGGTTTGAAAATGCCACGTGGAATCGCGGTGGACTGGGTGGCTGGTAACCTCTACTGGACCGATTCAGGACGTGATGTGATCGAGGTTGCTCAGCTTACAGGCCAGCACAGAAAAACGCTAATTTCTGGCATGATTGACGAGCCTTACGCTATTGTAGTGGATCCTCAAAGAGGAACCATGTACTGGACAGACTGGGGTAATCATCCAAAGATTGAGATGGCAGCCATGGATGGCACTCTCAGACAAACCCTGGTCCATGAGAACATCCAGTGGCCCACAGGTCTTGCAGTAGACTACTTCAATGAGCGTCTGTACTGGGCAGATGTCAAACTTTCCATGATTGGCAGTGTGCGTCTGGATGGCTCTGACCCTGTTGTGGCTGTATCCAACATCAAAAACAATCTCCTCCACCCCTTCAGCATTGATATCTTTGAGGATTACATATATGGGGTTACCTACACCAATAACGTTGTCTTCCGAGTTAACAAGTTTGGTAAAGGCCAGGCAGAGAATCTGACCACTGGCATCAACCATGCCACTGACATAGCCCTCCATCACCGCTACAAACAGCCTGAGACCCCCACCTGTAACGTTCAGTGTCAGAATGGCGGCAGCTGTTTCCTCACTCCGTGGAACCAGCCCAAATGTCGCTGCCCCACCAGTTACAGTGGAGAACGCTGTGAAATCAACAAGTGCAGGGACTACTGTCAGAATGGAGGAACATGCTCCCCATCACGCACAGGTGCTCCTACCTGTCGCTGTCAGACTGGCTTCACCGGATCCAGATGTGAACAGCACACTTGTAATAACTACTGCCAGAATGAGGGCACCTGCACTGTCAGCCAGGGCAACCAGCCAACCTGTCGTTGTCCAAAAGGCTTCCTGGGTGACCAGTGCCAGTACCGTCAATGTGATGACTTCTGTAAGAATGAAGGTCTTTGTATGGAGATGATGAACGGCACTAAACAGTGCCACTGTAACGAGTCGTTCTTTGGTCCACAATGTGAGATGAACAAGTGTGAATACTGCGGCACGGGCAAGTGTGAAGTACTACGAACTGGAATAACATGCAAATGTGGTGATAACATCCAGCGTCCCACCTGTTACACCTGTGATGACTTCTGCATTGAGGGCCAGTGCTCTGTAGACCCTCATACTATGCTGCCACAGTGCAGATGTCACACAGGCTGGTCAGGTTTTCGCTGTGAGCTCAATATTGCCCCTGTTCAGAACCCAGACTCTGGAAATACTCCATCAGTGGTCATCCCAGTGATGTTACTGCTCTTACTTGCACTGTTAGTAGTTGGTGCCATCTTGTGGTACAAGAAGAGAATGCGTGGAGCTAAGGGATTCCAGCACCAGAGGATGACCAACGGAGCCATGAATGTTGAGATCGGGAACCCGGCATACAAGATTTATGAAGGAGAGCCCGATGATGATGCGGGGGAACTGCTGGACTCCGACTTCACCTTGGATCCAGATAAGAACCAGAGCCAGATGACGGAGGATGTGCATGAATTTGTTCTCTTGCTGCGTCAAGATCTCTGCAAACCTAGTGAAAACGATACCACTGAACAGAGCACTTTACTGCAAGGCTTTGGCCTTGTCGTCTTTGAAGAGGAAGATGAGGAAGACGAGGAGGGTGAAGTTGCTGACTTGAGCTCTATGAAATCATGTTGCTACCCAAATCCTAGTTACAGAGGACAGACGCTACACCTGCCAGAGCCTTTCCACATGACAGATAGCACATTAAAAGACAGTGACACAGAGTCCACATACAGAAATGGCCTGTTCTTTGAAACGAGAATCATTGAGAGTGATAAAACATCACTATAGTCTTGTCTGGTCTTGTTTGTGACGAGTTCTGACAA

Function

symbol description
lrp1ab Predicted to enable calcium ion binding activity. Acts upstream of or within regulation of vasculature development. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; keratosis pilaris atrophicans; myocardial infarction; and sciatic neuropathy. Orthologous to human LRP1 (LDL receptor related protein 1).
lrp1 Enables alpha-2 macroglobulin receptor activity; apolipoprotein binding activity; and clathrin heavy chain binding activity. Involved in several processes, including amyloid-beta clearance by cellular catabolic process; amyloid-beta clearance by transcytosis; and positive regulation of lysosomal protein catabolic process. Located in basolateral plasma membrane and early endosome. Part of receptor complex. Implicated in Alzheimer's disease; keratosis pilaris atrophicans; myocardial infarction; and sciatic neuropathy.

GO:

id name namespace
GO:0016020 membrane cellular_component

KEGG:

id description
K04550 LRP1, CD91; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000051_07470914_07489207.mRNA True 4666 mRNA 0.50 32 7470914 7489242

Neighbor

gene id symbol gene type direction distance location
CI01000051_07391277_07399712 ABCB11B, ABCB11 coding upstream 71128 7390634 ~ 7399786 (+)
CI01000051_07378590_07389158 ABCB11B, ABCB11 coding upstream 81344 7378590 ~ 7389570 (+)
CI01000051_07367270_07370738 ATP5B coding upstream 100036 7366852 ~ 7370878 (+)
CI01000051_07345863_07353841 MKNK1 coding upstream 115794 7345863 ~ 7355120 (+)
CI01000051_07337005_07340657 MOB3C, MOB3C.S, MOBKL2C coding upstream 130222 7336853 ~ 7340692 (+)
CI01000051_07507549_07530087 HOMER3 coding downstream 18307 7507549 ~ 7530087 (+)
CI01000051_07534938_07540104 NA coding downstream 43397 7532639 ~ 7540418 (+)
CI01000051_07542167_07549737 ARRDC2 coding downstream 52925 7542167 ~ 7550660 (+)
CI01000051_07611022_07612093 NA coding downstream 121207 7610449 ~ 7612093 (+)
CI01000051_07634084_07726089 NA coding downstream 144637 7633879 ~ 7726109 (+)
G221409 NA non-coding upstream 15377 7455331 ~ 7455537 (+)
G221408 NA non-coding upstream 18903 7451740 ~ 7452011 (+)
G221406 NA non-coding upstream 20024 7450479 ~ 7450890 (+)
G221336 NA non-coding upstream 45495 7422923 ~ 7425419 (+)
G221386 NA non-coding upstream 57907 7401175 ~ 7413007 (+)
G221333 NA non-coding downstream 315109 7804351 ~ 7840774 (+)
CI01000051_07806350_07831779 GRIN3B non-coding downstream 330455 7806350 ~ 7832334 (+)
G221530 NA non-coding downstream 506780 7996022 ~ 7996297 (+)
G221538 NA non-coding downstream 519673 8008915 ~ 8009351 (+)
G221539 NA non-coding downstream 527002 8016244 ~ 8016535 (+)
G221319 NA other upstream 128368 7342041 ~ 7342546 (+)
CI01000051_06825895_06830637 NA other upstream 637846 6825895 ~ 6830637 (+)
G219803 NA other upstream 2418881 4914974 ~ 5052033 (+)
CI01000051_04374052_04393328 NA other upstream 3095584 4372658 ~ 4393677 (+)
CI01000051_08211233_08214513 NA other downstream 616401 8209722 ~ 8214696 (+)
G222727 NA other downstream 853700 8342942 ~ 8343448 (+)

Expression


Co-expression Network